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胆囊癌的手术治疗管理联合多柔比星治疗的效果分析
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作者 古再丽努尔.阿布力孜 林红玉 +1 位作者 戴志兵 范志勤 《肿瘤药学》 CAS 2018年第6期935-938,共4页
目的探究胆囊癌的手术治疗管理联合多柔比星治疗的效果及对患者生活质量的影响。方法选取我院收治的140例胆囊癌患者,按数字表法随机分为对照组(70例)和观察组(70例)。对照组患者在手术的基础上加强管理,观察组患者在手术联合多柔比星... 目的探究胆囊癌的手术治疗管理联合多柔比星治疗的效果及对患者生活质量的影响。方法选取我院收治的140例胆囊癌患者,按数字表法随机分为对照组(70例)和观察组(70例)。对照组患者在手术的基础上加强管理,观察组患者在手术联合多柔比星治疗的基础上加强管理。比较两组患者的治疗有效率、生活质量以及不良反应发生率。结果观察组患者治疗有效率显著高于对照组(P<0.05),不良反应发生率明显低于对照组(P<0.05),焦虑抑郁评分明显低于对照组(P<0.05)。治疗前,观察组患者社会功能、躯体功能、角色功能以及认知功能评分与对照组无明显差异(P>0.05),治疗后,观察组患者生活质量评分均明显高于对照组(P<0.05)。结论手术治疗管理联合多柔比星治疗胆囊癌的效果更佳,可显著改善患者生活质量,值得临床进一步推广应用。 展开更多
关键词 胆囊癌 手术治疗管理 多柔比星 治疗有效率 生活质量
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Iatrogenic bile duct injuries:Etiology,diagnosis and management 被引量:18
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作者 Beata Jab■ońska Pawe■ Lampe 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第33期4097-4104,共8页
Iatrogenic bile duct injuries (IBDI) remain an important problem in gastrointestinal surgery. They are most frequently caused by laparoscopic cholecystectomy which is one of the commonest surgical procedures in the wo... Iatrogenic bile duct injuries (IBDI) remain an important problem in gastrointestinal surgery. They are most frequently caused by laparoscopic cholecystectomy which is one of the commonest surgical procedures in the world. The early and proper diagnosis of IBDI is very important for surgeons and gastroenterologists, because unrecognized IBDI lead to serious complications such as biliary cirrhosis, hepatic failure and death. Laboratory and radiological investigations play an important role in the diagnosis of biliary injuries. There are many classifications of IBDI. The most popular and simple classification of IBDI is the Bismuth scale. Endoscopic techniques are recommended for initial treatment of IBDI. When endoscopic treatment is not effective, surgical management is considered. Different surgical reconstructions are performed in patients with IBDI. According to the literature, Roux- en-Y hepaticojejunostomy is the most frequent surgical reconstruction and recommended by most authors. In the opinion of some authors, a more physiological and equally effective type of reconstruction is end- to-end ductal anastomosis. Long term results are the most important in the assessment of the effectiveness of IBDI treatment. There are a few classifications for the long term results in patients treated for IBDI; the Terblanche scale, based on clinical biliary symptoms, is regarded as the most useful classification. Proper diagnosis and treatment of IBDI may avoid many serious complications and improve quality of life. 展开更多
关键词 Iatrogenic disease Biliary drainage Bile ducts CHOLECYSTECTOMY Roux-en-Y anastomosis Surgical injuries Surgical anastomosis
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Optimizing management of pancreaticopleural fistulas 被引量:7
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作者 Marek Wronski Maciej Slodkowski +2 位作者 Wlodzimierz Cebulski Daniel Moronczyk Ireneusz W Krasnodebski 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第42期4696-4703,共8页
AIM:To evaluate the management of pancreaticopleural fistulas involving early endoscopic instrumentation of the pancreatic duct.METHODS:Eight patients with a spontaneous pancre-aticopleural fistula underwent endoscopi... AIM:To evaluate the management of pancreaticopleural fistulas involving early endoscopic instrumentation of the pancreatic duct.METHODS:Eight patients with a spontaneous pancre-aticopleural fistula underwent endoscopic retrograde cholang iopancreatography(ERCP) with an intentionto stent the site of a ductal disruption as the primarytreatment. Imaging features and management were evaluated retrospectively and compared with outcome.RESULTS:In one case,the stent bridged the site of aductal disruption. The fistula in this patient closed with in3 wk. The main pancreatic duct in this case appearednormal,except for a leak located in the body of the pancreas. In another patient,the papilla of Vater couldnot be found and cannulation of the pancreatic ductfailed. This patient underwent surgical treatment. In the remaining 6 cases,it was impossible to insert a stentinto the main pancreatic duct properly so as to coverthe site of leakage or traverse a stenosis situated down-stream to the fistula. The placement of the stent failed because intraductal stones(n = 2) and ductal strictures(n = 2) precluded its passage or the stent was too short to reach the fistula located in the distal part of the pancreas(n = 2) . In 3 out of these 6 patients,the pancre-aticopleural fistula closed on further medical treatment.In these cases,the main pancreatic duct was normalor only mildly dilated,and there was a leakage at the body/tail of the pancreas. In one of these 3 patients,additional percutaneous drainage of the peripancre atic fluid collections allowed better control of the leakageand facilitated resolution of the fistula. The remaining3 patients had a tight stenosis of the main pancreatic duct resistible to dilatation and the stent could not beinserted across the stenosis. Subsequent conservative treatment proved unsuccessful in these patients. Aftera failed the rapeutic ERCP,3 patients in our series developed superinfection of the pleural or peripancreatic fluid collections. Four out of 8 patients in our series required subsequent surgery due to a failed non-operative treat-ment. Distal pancreatectomy with splenectomy was performed in 3 cases. In one case,only external drainage of the pancreatic pseudocyst was done because of diffuse peripancreatic inflammatory infiltration precluding safe dissection. There were no perioperative mortalities.There was no recurrence of a pancreati copleural fistulain any of the patients.CONCLUSION:Optimal management of pancreaticopleural fistulas requires appropriate patient selection that should be based on the underlying pancreatic ductab normalities. 展开更多
关键词 Pancreaticopleural fistula PANCREATITIS SURGERY Endoscopic retrograde cholangiopancreatography Magnetic resonance cholangiopancreatography
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Incidental gallbladder cancer during laparoscopic cholecystectomy:Managing an unexpected finding 被引量:37
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作者 Andrea Cavallaro Gaetano Piccolo +5 位作者 Vincenzo Panebianco Emanuele Lo Menzo Massimiliano Berretta Antonio Zanghì Maria Di Vita Alessandro Cappellani 《World Journal of Gastroenterology》 SCIE CAS CSCD 2012年第30期4019-4027,共9页
AIM:To evaluate the impact of incidental gallbladder cancer on surgical experience.METHODS:Between 1998 and 2008 all cases of cholecystectomy at two divisions of general surgery,one university based and one at a publi... AIM:To evaluate the impact of incidental gallbladder cancer on surgical experience.METHODS:Between 1998 and 2008 all cases of cholecystectomy at two divisions of general surgery,one university based and one at a public hospital,were retrospectively reviewed.Gallbladder pathology was diagnosed by history,physical examination,and laboratory and imaging studies [ultrasonography and computed tomography(CT)].Patients with gallbladder cancer(GBC) were further analyzed for demographic data,and type of operation,surgical morbidity and mortality,histopathological classification,and survival.Incidental GBC was compared with suspected or preoperatively diagnosed GBC.The primary endpoint was diseasefree survival(DFS).The secondary endpoint was the difference in DFS between patients previously treated with laparoscopic cholecystectomy and those who had oncological resection as first intervention.RESULTS:Nineteen patients(11 women and eight men) were found to have GBC.The male to female ratio was 1:1.4 and the mean age was 68 years(range:45-82 years).Preoperative diagnosis was made in 10 cases,and eight were diagnosed postoperatively.One was suspected intraoperatively and confirmed by frozen sections.The ratio between incidental and nonincidental cases was 9/19.The tumor node metastasis stage was:pTis(1),pT1a(2),pT1b(4),pT2(6),pT3(4),pT4(2);five cases with stageⅠa(T1 a-b);two with stageⅠb(T2 N0);one with stage Ⅱa(T3 N0);six with stage Ⅱb(T1-T3 N1);two with stage Ⅲ(T4 Nx Nx);and one with stage Ⅳ(Tx Nx Mx).Eighty-eight percent of the incidental cases were discovered at an early stage(≤Ⅱ).Preoperative diagnosis of the 19 patients with GBC was:GBC with liver invasion diagnosed by preoperative CT(nine cases),gallbladder abscess perforated into hepatic parenchyma and involving the transversal mesocolon and hepatic hilum(one case),porcelain gallbladder(one case),gallbladder adenoma(one case),and chronic cholelithiasis(eight cases).Every case,except one,with a T1b or more advanced invasion underwent Ⅳb + Ⅴ wedge liver resection and pericholedochic/hepatoduodenal lymphadenectomy.One patient with stage T1b GBC refused further surgery.Cases with Tis and T1a involvement were treated with cholecystectomy alone.One incidental case was diagnosed by intraoperative frozen section and treated with cholecystectomy alone.Six of the nine patients with incidental diagnosis reached 5-year DFS.One patient reached 38 mo survival despite a port-site recurrence 2 years after original surgery.Cases with non incidental diagnosis were more locally advanced and only two patients experienced 5-year DFS.CONCLUSION:Laparoscopic cholecystectomy does not affect survival if implemented properly.Reoperation should have two objectives:R0 resection and clearance of the lymph nodes. 展开更多
关键词 Incidental gallbladder cancer Laparoscopic cholecystectomy Lymph nodes Hepatic resection Management Outcome
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Role of surgical intervention in managing gastrointestinal metastases from lung cancer 被引量:7
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作者 Po-Chu Lee Chiao Lo +2 位作者 Ming-Tsan Lin Jin-Tung Liang Been-Ren Lin 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第38期4314-4320,共7页
AIM:To investigate the clinicopathological characteristics of late-stage lung cancer patients with gastrointestinal(GI)-tract metastases,focusing on therapeutic options and outcomes.METHODS:Our institution(the Nationa... AIM:To investigate the clinicopathological characteristics of late-stage lung cancer patients with gastrointestinal(GI)-tract metastases,focusing on therapeutic options and outcomes.METHODS:Our institution(the National Taiwan University Hospital) diagnosed 8159 patients with lung cancer between 1987 and 2008,of which 21 developed symptomatic GI metastases.This study reviewed all of the patients' information,including survival data,pathological reports,and surgical notes.RESULTS:The most common histological type of lung cancer was adenocarcinoma,and 0.26% of patients with lung cancer developed GI metastases.The median duration from lung cancer diagnosis to GI metastases was three months(range,0-108 mo),and the average time from diagnosis of GI metastasis to death was 2.8 mo.Most patients with symptomatic gastric and/or duodenal metastases exhibited GI bleeding and were diagnosed by panendoscopy.In contrast,small bowel metastases typically presented as an acute abdomen and were not diagnosed until laparotomy.All patients with small bowel or colonic metastases underwent surgical intervention,and their perioperative mortality was 22%.Our data revealed a therapeutic effect in patients with solitary GI metastasis and a favorable palliative effect on survival when metastases were diagnosed preoperatively.In patients with multiple GI metastases,the presentation varied according to the locations of the metastases.CONCLUSION:Surgical treatment is worthwhile in a select group of patients with bowel perforation or obstruction.Physicians should be more alert to symptoms or signs indicating GI metastases. 展开更多
关键词 Gastrointestinal metastasis Lung cancer Palliative effect Prognosis Surgical intervention
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Long-term survival after intraluminal brachytherapy for inoperable hilar cholangiocarcinoma: A case report 被引量:7
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作者 Siu-Yin Chan Ronnie T. Poon +3 位作者 Kelvin K. Ng Chi-Leung Liu Raymond T. Chan Sheung-Tat Fan 《World Journal of Gastroenterology》 SCIE CAS CSCD 2005年第20期3161-3164,共4页
Surgical resection with a tumor-free margin is the onlycurative treatment for hilar cholangiocarcinoma (Klatskin tumor). However, over half of the patients present late with unresectable tumors. Radiotherapy using ext... Surgical resection with a tumor-free margin is the onlycurative treatment for hilar cholangiocarcinoma (Klatskin tumor). However, over half of the patients present late with unresectable tumors. Radiotherapy using external beamirradiation or intraluminal brachytherapy (ILBT) has been used to treat unresectable hilar cholangiocarcinoma with satisfactory outcome. We reported a patient with unresectable hilar cholangiocarcinoma surviving more than 6 years after combined external beam irradiation and ILBT. 展开更多
关键词 BRACHYTHERAPY Hilar cholangiocarcinoma
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Non-surgical treatment of esophageal achalasia 被引量:16
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作者 Vito Annese Gabrio Bassotti 《World Journal of Gastroenterology》 SCIE CAS CSCD 2006年第36期5763-5766,共4页
Esophageal achalasia is an infrequent motility disorder characterized by a progressive stasis and dilation of the oesophagus; with subsequent risk of aspiration, weight loss, and malnutrition. Although the treatment o... Esophageal achalasia is an infrequent motility disorder characterized by a progressive stasis and dilation of the oesophagus; with subsequent risk of aspiration, weight loss, and malnutrition. Although the treatment of achalasia has been traditionally based on a surgical approach, especially with the introduction of laparoscopic techniques, there is still some space for a medical approach. The present article reviews the non-surgical therapeutic options for achalasia. 展开更多
关键词 ACHALASIA Botulinum toxin Pneumatic dilatation
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Surgical treatment of giant esophageal leiomyoma 被引量:5
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作者 Bang-Chang Cheng Sheng Chang +4 位作者 Zhi-Fu Mao Mao-Jin Li Jie Huang Zhi-Wei Wang Tu-Sheng Wang 《World Journal of Gastroenterology》 SCIE CAS CSCD 2005年第27期4258-4260,共3页
AIM: To summarize the operative experiences for giant leiomyoma of esophagus.METHODS: Eight cases of giant esophageal leiomyoma (GEL) whose tumors were bigger than 10 cm were treated surgically in our department f... AIM: To summarize the operative experiences for giant leiomyoma of esophagus.METHODS: Eight cases of giant esophageal leiomyoma (GEL) whose tumors were bigger than 10 cm were treated surgically in our department from June 1980 to March 2004.All of these cases received barium swallow roentgenography and esophagoscopy. Leiomyoma located in upper thirds of the esophagus in one case, middle thirds of the esophagus in five cases, lower thirds of the esophagus in two cases. Resection of tumors was performed successfully in all of these cases. Operative methods included transthoracic extramucosal enucleation and buttressing the muscular defect with pedicled great omental flap (one case), esophagectomy and esophagogastrostomy above the arch of aorta (three cases), total esophagectomy and esophageal replacement with colon (four cases). Histological examination confirmed that all of these cases were leiomyoma.RESULTS: All of the eight patients recovered approvingly with no mortality and resumed normal diet after operation. Vomiting during meals occurred in one patient with esophagogastrostomy, and remained 1 mo. Reflux esophagitis occurred in one patient with esophagogastrostomy and was alleviated with medication. Thoracic colon syndrome (TCS) occurred in one patient with colon replacement at 15 mo postoperatively. No recurrence occurred in follow-up from 6 mo to 8 years.CONCLUSION: Surgical treatment for GEL is both safe and effective. The choices of operative methods mainly depend on the location and range of lesions. We prefer to treat GEL via esophagectomy combined with esophagogastrostomy or esophagus replacement with colon. The long-time quality of life is better in the latter. 展开更多
关键词 Giant esophageal leiomyoma ESOPHAGUS Greater omentum Esophageal replacement with colon
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Surgical management in biliary restricture after Roux-en-Y hepaticojejunostomy for bile duct injury 被引量:6
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作者 Ji-Qi Yan Cheng-Hong Peng Jia-Zeng Ding Wei-Ping Yang Guang-Wen Zhou Yong-Jun Chen Zong-Yuan Tao Hong-Wei Li 《World Journal of Gastroenterology》 SCIE CAS CSCD 2007年第48期6598-6602,共5页
AIM: To discuss the surgical method and skill of biliary restricture after Roux-en-Y hepaticojejunostomy for bile duct injury. METHODS: From November 2005 to December 2006, eight patients with biliary restricture afte... AIM: To discuss the surgical method and skill of biliary restricture after Roux-en-Y hepaticojejunostomy for bile duct injury. METHODS: From November 2005 to December 2006, eight patients with biliary restricture after Roux-en-Y hepaticojejunostomy for bile duct injury were admitted to our hospital. Their clinical data were analyzed retrospectively. RESULTS: Bile duct injury was caused by cholecys- tectomy in the eight cases, including seven cases with laparoscopic cholecystectomy and one with mini- incision choleystectomy. According to the classification of Strasberg, type E1 injury was found in one patient, type E2 injury in three, type E3 injury in two and type E4 injury in two patients. Both of the type E4 injury patients also had a vascular lesion of the hepatic artery. Six patients received Roux-en-Y hepaticojejunostomy for the second time, and one of them who had type E4 injury with the right hepatic artery disruption received right hepatectomy afterward. One patient who had type E4 injury with the proper hepatic artery lesion underwent liver transplantation, and the remaining one with type E3 injury received external biliary drainage. All the patients recovered fairly well postoperatively. CONCLUSION: Roux-en-Y hepaticojejunostomy is still the main approach for such failed surgical cases with bile duct injury. Special attention should be paid to concomitant vascular injury in these cases. The optimal timing and meticulous and excellent skills are essential to the success in this surgery. 展开更多
关键词 Bile duct injury Biliary stricture Roux-en-Y hepaticojejunostomy Hepatic artery injury
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URETERAL INJURY DURING GYNECOLOGICAL LAPAROSCOPIC SURGERIES: REPORT OF TWELVE CASES 被引量:9
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作者 Jin-song Gao Jin-hua Leng Zhu-feng Liu Keng Shen Jing-he Lang 《Chinese Medical Sciences Journal》 CAS CSCD 2007年第1期13-16,共4页
Objective To investigate ureteral injury during gynecological laparoscopic surgeries.Methods From January 1990 to December 2005, 12868 gynecological laparoscopic surgeries were conducted in Peking Union Medical Colleg... Objective To investigate ureteral injury during gynecological laparoscopic surgeries.Methods From January 1990 to December 2005, 12868 gynecological laparoscopic surgeries were conducted in Peking Union Medical College Hospital with 12 ureteral injuries reported. The present study investigated several aspects, including surgical indications, uterine size, pelvic adhesion, operative procedures, symptoms, diagnostic time and methods, injury site and type, subsequent treatment, and prognosis. Results The incidence of ureteral injury was 0.093% (12/12868) in all cases, 0.42% (11/2586) in laparoscopic hysterectomy [laparoscopically assisted vaginal hysterectomy (LAVH) or total laparoscopic hysterectomy (TLH)], and 0.01% (1/10282) in non-LAVH surgeries. Enlarged uterus, pelvic adhesion, and endometrosis were risk factors associated with ureteral injury. Only one injury was found intraoperatively while others were found postoperatively. The injury sites were at the pelvic brim (2 cases) or the lower part of ureter (10 cases). Patients were treated with ureteral stenting (effective in 2 cases) or laparotomy and open repair. Prognoses were favorable in most cases. Conclusions Most laparoscopic ureteral injuries occur during laparoscopic hysterectomy. Further evaluation is required when ureteral injury is suspected, and surgical repair is the major treatment for ureteral injury. 展开更多
关键词 ureteral injury LAPAROSCOPY iatrogenic complication
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Current management strategy of hepatocellular carcinoma 被引量:50
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作者 Bernardino Rampone Beniamino Schiavone +2 位作者 Antonio Martino Carmine Viviano Giuseppe Confuorto 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第26期3210-3216,共7页
Hepatocellular carcinoma (HCC) still remains a considerable challenge for surgeons.Surgery,including liver transplantation,is the most important therapeutic approach for patients with this disease.HCC is frequently di... Hepatocellular carcinoma (HCC) still remains a considerable challenge for surgeons.Surgery,including liver transplantation,is the most important therapeutic approach for patients with this disease.HCC is frequently diagnosed at advanced stages and has a poor prognosis with a high mortality rate even when surgical resection has been considered potentially curative.This brief report summarizes the current status of the management of this malignancy and includes a short description of new pharmacological approaches in HCC treatment. 展开更多
关键词 Hepatocellular carcinoma Locoregional procedures Liver transplantation Surgical resection Systemic treatment
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Perianal Crohn's disease: Is there something new? 被引量:3
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作者 Cesare Ruffolo Marilisa Citton +4 位作者 Marco Scarpa Imerio Angriman Marco Massani Ezio Caratozzolo Nicolò Bassi 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第15期1939-1946,共8页
Perianal lesions are common in patients with Crohn's disease, and display aggressive behavior in some cases. An accurate diagnosis is necessary for the optimal management of perianal lesions. Treatment of perianal... Perianal lesions are common in patients with Crohn's disease, and display aggressive behavior in some cases. An accurate diagnosis is necessary for the optimal management of perianal lesions. Treatment of perianal Crohn's disease includes medical and/or surgical options. Recent discoveries in the pathogenesis of this disease have led to advances in medical and surgical therapy with good results. Perianal lesions in Crohn's disease remain a challenging aspect for both gastroenterologists and surgeons and lead to a greatly impaired quality of life for all patients affected by this disease. A multidisciplinary approach is mandatory to obtain the best results. 展开更多
关键词 Crohn disease DIAGNOSIS Biologic therapy SURGERY Rectal fistula
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A comparative study of the therapeutic effect in two protocols: video-assisted thoracic surgery combined with laparoscopy versus right open transthoracic esophagectomy for esophageal cancer management 被引量:3
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作者 Ming Guo Baiyi Xie +3 位作者 Xiaoyan Sun Meng Hu Qingjie Yang Yunhong Lei 《The Chinese-German Journal of Clinical Oncology》 CAS 2013年第2期68-71,共4页
Objective: The aim was to evaluate the best intra-thoracoscopic surgery technique between video-assisted thoracic surgery (VATS) combined with laparoscopy and right open transthoracic esophagectomy, in patients with e... Objective: The aim was to evaluate the best intra-thoracoscopic surgery technique between video-assisted thoracic surgery (VATS) combined with laparoscopy and right open transthoracic esophagectomy, in patients with esophageal cancer. Methods: From November 2006 to May 2008, 221 patients with esophageal cancer were enrolled in this study, prospective randomized in two groups. 111 patients were performed the VATS technique (Experimental group), whereas in the other 110 patients esophagectomy was adopted by thoracotomy (Control group). Results: The time consuming of Experimental group was 272.3 min in average with a standard deviation(std) of 57.9, and it was 218.7 min in average with std of 91.0 in the control group (P=0.000). The operative blood loss was 219.7±194.4 mL in the Experimental group, compared with 590.0±324.4 mL in the control group, with significant difference (P=0.000). Postoperative hospital stay of Experimental group was 9.6±1.7d, and it was 11.4±2.3d in the control group (P=0.000). There was no-delayed union of incision in the Experimental group, but 6.36% in the control group (P=0.007). The disorder of gastric emptying occurred 0.9% in the Experimental group, whereas 6.4% in the Control group. There was no significant difference in survival curves and rates (P=0.555). Conclusion: There were several advantages of VATS technique, such as reduced hemorrhage, better recovery, few complications, and great number of lymph node dissection, although there was no significant difference in long-term survival rate. Thus the VATS combined with laparoscopy technique was worthy of generalization in esophageal surgery with good prospects. 展开更多
关键词 video-assisted thoracic surgery (VATS) LAPAROSCOPY esophageal cancer
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Hemorrhoids:From basic pathophysiology to clinical management 被引量:81
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作者 Varut Lohsiriwat 《World Journal of Gastroenterology》 SCIE CAS CSCD 2012年第17期2009-2017,共9页
This review discusses the pathophysiology,epidemiology,risk factors,classification,clinical evaluation,and current non-operative and operative treatment of hemorrhoids.Hemorrhoids are defined as the symptomatic enlarg... This review discusses the pathophysiology,epidemiology,risk factors,classification,clinical evaluation,and current non-operative and operative treatment of hemorrhoids.Hemorrhoids are defined as the symptomatic enlargement and distal displacement of the normal anal cushions.The most common symptom of hemorrhoids is rectal bleeding associated with bowel movement.The abnormal dilatation and distortion of the vascular channel,together with destructive changes in the supporting connective tissue within the anal cushion,is a paramount finding of hemorrhoids.It appears that the dysregulation of the vascular tone and vascular hyperplasia might play an important role in hemorrhoidal development,and could be a potential target for medical treatment.In most instances,hemorrhoids are treated conservatively,using many methods such as lifestyle modification,fiber supplement,suppositorydelivered anti-inflammatory drugs,and administration of venotonic drugs.Non-operative approaches include sclerotherapy and,preferably,rubber band ligation.An operation is indicated when non-operative approaches have failed or complications have occurred.Several surgical approaches for treating hemorrhoids have been introduced including hemorrhoidectomy and stapled hemorrhoidopexy,but postoperative pain is invariable.Some of the surgical treatments potentially cause appreciable morbidity such as anal stricture and incontinence.The applications and outcomes of each treatment are thoroughly discussed. 展开更多
关键词 Hemorrhoids Pathophysiology Treatment Management Outcome
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Surgical risk for patients with Chagasic achalasia and its correlation with the degree of esophageai dilation
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作者 José Garcia Neto Roberto de Cleva +1 位作者 Bruno Zilberstein Joaquim José Gama-Rodrigues 《World Journal of Gastroenterology》 SCIE CAS CSCD 2005年第37期5840-5844,共5页
AIM: To analyze the risk of cardiovascular complications in patients with indication for surgical treatment of Chagasic esophageal achalasia and to correlate the surgical risks with the degree of esophageal dilation,... AIM: To analyze the risk of cardiovascular complications in patients with indication for surgical treatment of Chagasic esophageal achalasia and to correlate the surgical risks with the degree of esophageal dilation, thereby proposing a risk scale index. METHODS: One hundred and twenty-four patients with Chagasic esophageal achalasia, who received surgical treatment at the Hospital das Clinicas of the Federal University of Goiás, were included in this study. The patients were mostly related to the postoperative complications due to the cardiovascular system. All the patients were submitted to: (1) clinical history to define the cardiac functional class (New York Heart Association); (2) conventional 12-lead electrocardiogram at rest; and (3) contrast imaging of the esophagus to determine esophageal dilatation according to Rezende's classification of Chagasic megaesophagus. RESULTS: An assessment of the functional classification (FC) of heart failure during the preoperative period determined that 67 patients (54.03%) were assigned functional class Ⅰ (FC Ⅰ), 46 patients (37.09%) were assigned functional class Ⅱ (FC Ⅱ), and 11 patients (8.87%) were assigned functional class Ⅲ (FC Ⅲ). None of the patients were assigned to functional class Ⅳ (FC Ⅳ). There was a positive correlation between the functional class and the postoperative complications (FC Ⅰ×FC Ⅱ: P〈0.001; FC Ⅰ×FC Ⅲ: P〈0.001). The ECG was normal in 44 patients (35.48%) and presented abnormalities in 80 patients (64.52%). There was a significant statistical correlation between abnormal ECG (arrhythmias and primary change in ventricular repolarization) and postoperative complications (P〈0.001). With regard to the classification of the Chagasic esophageal achalasia, the following distribution was observed: group Ⅱ, 53 patients (42.74%); group Ⅲ, 37 patients (29.83%); and group Ⅳ, 34 patients (27.41%). There was a positive correlation between the degree of esophageal dilation and the increase in postoperative complications (grade Ⅱ×grade Ⅲ achalasia: P〈0.001; grade Ⅱ×grade Ⅳ achalasia: P〈0.001; and grade Ⅲ×grade Ⅳ achalasia: P = 0.017). Analyzing these results and using a multivariate regression analysis associated with the probability decision analysis, a risk scale was proposed as follows: up to 21 points (mild risk); from 22 to 34 points (moderate risk); and more than 34 points (high risk). The scale had 82.4% accuracy for mild risk patients and up to 94.6% for the high risk cases. CONCLUSION: The preoperative evaluation of the cardiovascular system, through a careful anamnesis, an ECG and contrast imaging of the esophagus, makes possible to estimate the surgical risks for Chagas' disease patients who have to undergo surgical treatment for esophageal achalasia. 展开更多
关键词 POSTOPERATIVE Chagas' disease Surgical risk Chagasic achalasia Cardiovascular risk
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Anaplastic carcinoma of pancreas:report of 6 cases and literature review
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作者 邵成浩 胡先贵 +4 位作者 高莉 唐岩 刘瑞 张怡杰 周颖奇 《Journal of Medical Colleges of PLA(China)》 CAS 2005年第3期186-190,共5页
Objective:To investigate clinicopathological features,diagnosis and treatment of anaplastic carcinoma of the pancreas and to review relevant literature on this entity. Methods:A retrospective clinical analysis was mad... Objective:To investigate clinicopathological features,diagnosis and treatment of anaplastic carcinoma of the pancreas and to review relevant literature on this entity. Methods:A retrospective clinical analysis was made in 6 cases of anaplastic pancreatic carcinomas admitted from 1989 to 2001. Results:Anaplastic pancreatic carcinoma was found in 5 men and 1 woman with a mean age of 61.5 years.Tumor location was in the head of the pancreas in 3 patients,body and tail in 3 cases.Tumors were surgically resected in all patients,by pancreaticoduodenectomy in 1,by pancreaticoduodenectomy combined resection and reconstruction of superior mesenteric vein(SMV) in 1,by pancreaticoduodenectomy combined resection and reconstruction of SMV and superior mesenteric artery(SMA) in 1,by distal pancreatectomy in 2,by distal pancreatectomy combined total gastrotectomy in 1.Liver metastasis was found in one patient.Follow-up suggested the prognosis was poor with a mean survival of 5.5 months after operation.All patients were dead with tumor recurrence and liver metastasis. Conclusion:Histologically,anaplastic pancreatic carcinoma is characterized by pleomorphic cell carcinoma consisting of pleomorphic giant/small cells and spindle cells,or osteoclast-like giant cell tumor composed of pleomorphic small cells,or pleomorphic giant cell carcinoma with osteoclastoid giant cells,and demonstrates aggressive biological behavior.Invasions to adjoined organ and metastasis are usual.The prognosis of this tumor appears to be very poor. 展开更多
关键词 pancreatic neoplasms anaplastic carcinoma PROGNOSIS
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Role of radiation therapy in the management of stage Ⅲ non-small cell lung cancers: current status and controversies
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作者 Wen Feng Xiaolong Fu 《The Chinese-German Journal of Clinical Oncology》 CAS 2015年第2期51-57,共7页
The treatment of stage Ⅲ non-small cell lung cancer(NSCLC) consisting of the heterogeneous stage subsets remains a challenge. Overall, it has been gradually recognized that radiation therapy(RT) plays a crucial role ... The treatment of stage Ⅲ non-small cell lung cancer(NSCLC) consisting of the heterogeneous stage subsets remains a challenge. Overall, it has been gradually recognized that radiation therapy(RT) plays a crucial role in the management of stage Ⅲ NSCLC. One superior sulcus tumors are the subset for which the trimodality treatments are clearly preferred. One subset of stage Ⅲ NSCLC has a minimal disease burden with microscopic p N2 disease or with discrete p N2 involvement identified preoperatively, thus technically could undergo a surgical resection. For the incidentally found p N2 disease after complete surgery(ⅢA-1, ⅢA-2), the value of postoperative radiotherapy(PORT) has been recognized by a reassessment based on new data. However, doubt persists regarding how to define the clinical target volume for PORT. For the discrete p N2 involvement identified preoperatively(a selected part of ⅢA-3), induction chemoradiation therapy(CRT) before surgery may yield a survival advantage, although the phase Ⅲ randomized trials in this issue are not conclusive. The other major subset of stage Ⅲ NSCLC is the infiltrative stage Ⅲ NSCLC with N2 or N3 nodal disease(ⅢA-3, ⅢA-4, and ⅢB), for which concurrent CRT is considered as the current standard of care. The potential role of radiation dose escalation/acceleration has been proposed; however, the optimal dose fractionation remains an important unresolved question. Additionally, the role of prophylactic cranial irradiation for stage Ⅲ patients with high risk of brain metastasis is worth of further assessment. Moreover, how to integrate molecular targeted therapy with RT, as well as whether they had a role in stage Ⅲ diseases, are other controversies actively under study in ongoing trials. This review specifically describes the updated role of RT in multimodal approach to treat stage Ⅲ NSCLC and the controversies regarding these results in various situations. 展开更多
关键词 non-small cell lang cancer (NSCLC) stage RADIOTHERAPY CHEMORADIOTHERAPY
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Immediate Surgical Intervention for Penile Fracture: a Case Report and Literature Review
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作者 Jin Wen Han-zhong Li Zhi-gang Ji Hong-jun Li 《Chinese Medical Sciences Journal》 CAS CSCD 2011年第2期132-134,共3页
PENILE fracture is a critical urological emergency, which is caused by the rupture of the tunica albuginea of the corpus cavernosum following blunt trauma to the erect penis. Traumatic injuries of the penis often occu... PENILE fracture is a critical urological emergency, which is caused by the rupture of the tunica albuginea of the corpus cavernosum following blunt trauma to the erect penis. Traumatic injuries of the penis often occur in the erected state.1 Due to the possible embarrassment, this condition has been under- reported. Typically, the patient reports a snap or cracking sound accompanied by sharp pain and rapid penile detu- mescence, followed by immediate development of swelling and angulation.2 The common causes include direct injuries, forceful masturbation, or vigorous sexual intercourse.3 Most injuries to the penis need immediate surgical treatment. Here we report a case of penile fracture caused by traumatic injury. 展开更多
关键词 penile fracture surgical intervention
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Assessment of duodenal circular drainage operations to treat superior mesenteric artery syndrome
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作者 杨维良 张新晨 《China Medical Abstracts》 2006年第1期64-66,63,共4页
Objective To assess the clinical value of duodenal circular drainage operation to treat superior mesenterie artery syndrome(SMAS). Methods Forty two cases of SMAS were treated with duodenal circular drainage operati... Objective To assess the clinical value of duodenal circular drainage operation to treat superior mesenterie artery syndrome(SMAS). Methods Forty two cases of SMAS were treated with duodenal circular drainage operation from 1959 to 2001. Clinical data were analyzed retrospectively. Results In this group, 37 cases were treated with duodenal circular drainage operation,and had good effect after follow- up of 1-15 years, the other 5 cases were first treated with anterior repositioning of the duodenum ( 1 case), gastroieiunostomy ( 1 case), duodeojejunostomy (2 cases), subtotal gastrectomy and Billroth 11 gastrojejunostomy(1 case) ,but vomiting was not relieved until duodenal circular drainage operation was performed again. Follow - up of 9- 10 years revealed good effect. Conclusion In SMAS, if the reversed peristalsis is stronger and continuous, and vomiting appears frequently, the symptom can not be relieved even if the obstruction of duodenum is removed by operation. The key treatment is the relief of reversed peristalsis. Only the duodenal circular drainage operation could resolve the drainage direction of duodenal content and relieve the symptom of vomiting. 展开更多
关键词 DUODENUM superior mesenterlc artery syndrome circular drainage operation
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Complete palmer lunate enucleation -- is proximal row carpectomy or wrist arthrodesis the only choice?
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作者 Atin Jaiswal Naiman Deepak Kachchhap +2 位作者 Yashwant S Tanwar Masood Habib Birendra Kumar 《Chinese Journal of Traumatology》 CAS CSCD 2013年第5期298-300,共3页
Perilunate dislocations are rare injuries of the wrist and complete dislocation of the lunate is also rare. There is controversy in literature regarding the optimal management of such injuries. Complete lunate enuclea... Perilunate dislocations are rare injuries of the wrist and complete dislocation of the lunate is also rare. There is controversy in literature regarding the optimal management of such injuries. Complete lunate enucleation is associated with high rate of osteonecrosis of lunate thus wrist arthrodesis or proximal row carpectomy has been ad- vocated as primary treatment for such injuries. We report a case of transradial styloid complete palmar lunate enucle- ation in a 25-year-old male patient who sustained injury to the left wrist due to fall on outstretched hand. Carpal row salvage surgery initially by closed reduction and wrist distractor application followed by open reduction and in- ternal fixation with K-wires along with ligamentous repair resulted in restoration of normal wrist anatomy and good functional outcome. As many of these injuries are missed on initial presentation and outcome is poor for missed injuries, prompt diagnosis and early surgical management to restore vascularity of lunate is recommended. 展开更多
关键词 WRIST Lunate bone Dislocations
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