The integrated linkage control problem based on attack detection is solved with the analyses of the security model including firewall, intrusion detection system (IDS) and vulnerability scan by game theory. The Nash...The integrated linkage control problem based on attack detection is solved with the analyses of the security model including firewall, intrusion detection system (IDS) and vulnerability scan by game theory. The Nash equilibrium for two portfolios of only deploying IDS and vulnerability scan and deploying all the technologies is investigated by backward induction. The results show that when the detection rates of IDS and vulnerability scan are low, the firm will not only inspect every user who raises an alarm, but also a fraction of users that do not raise an alarm; when the detection rates of IDS and vulnerability scan are sufficiently high, the firm will not inspect any user who does not raise an alarm, but only inspect a fraction of users that raise an alarm. Adding firewall into the information system impacts on the benefits of firms and hackers, but does not change the optimal strategies of hackers, and the optimal investigation strategies of IDS are only changed in certain cases. Moreover, the interactions between IDS & vulnerability scan and firewall & IDS are discussed in detail.展开更多
We report a rare case of extramedullary plasmocytoma associated with a massive deposit of amyloid in the duodenum. A 72-year-old Japanese man was admitted to our hospital presenting with a 3-mo history of epigastric p...We report a rare case of extramedullary plasmocytoma associated with a massive deposit of amyloid in the duodenum. A 72-year-old Japanese man was admitted to our hospital presenting with a 3-mo history of epigastric pain, vomiting and weight loss. On computed tomography (CT) a wall thickening of the fourth part of the duodenum was observed. Multiple biopsies obtained from the lesion showed infiltration of plasma cells and lymphocytes, but they were not conclusive. The patient underwent resection of the lesion and, on histopathological examination, the lesion consisted of a dense and diffuse infiltrate of plasma cells and a few admixed lymphocytes with reactive follicles extending to the muscular propria. An extensive deposition of amyloid was also observed. Immunohistochemical stains revealed that a few plasmacytoid cells showed λ light chain staining, though most were κ: light chain positive. These cells also were positive for CD138 and CD56 but negative for CD20 and CD79. The findings were consistent with extramedullary plasmocytoma associated with a massive deposit of amyloid in duodenum. A subsequent workup for multiple myeloma was completely negative. The patient showed no signs of local recurrence or dissemination of the disease after 12 mo follow-up. Because of the association of plasmocytoma and amyloidosis, the patient must be followed up because of the possible systemic involvement of the neoplasm and amyloidosis in future.展开更多
AIM:To quantitatively assess the ability of double contrast-enhanced ultrasound(DCUS) to detect tumor early response to pre-operative chemotherapy.METHODS:Forty-three patients with gastric cancer treated with neoadjuv...AIM:To quantitatively assess the ability of double contrast-enhanced ultrasound(DCUS) to detect tumor early response to pre-operative chemotherapy.METHODS:Forty-three patients with gastric cancer treated with neoadjuvant chemotherapy followed by curative resection between September 2011 and February 2012 were analyzed.Pre-operative chemotherapy regimens of fluorouracil + oxaliplatin or S-1 + oxaliplatin were administered in 2-4 cycles over 6-12 wk periods.All patients underwent contrast-enhanced computed tomography(CT) scan and DCUS before and after two courses of pre-operative chemotherapy.The therapeutic response was assessed by CT using the response evaluation criteria in solid tumors(RECIST 1.1) criteria.Tumor area was assessed by DCUS as enhanced appearance of gastric carcinoma due to tumor vascularity during the contrast phase as compared to the normal gastric wall.Histopathologic analysis was carried out according to the Mandard tumor regression grade criteria and used as the reference standard.Receiver operating characteristic(ROC) analysis was used to evaluate the efficacy of DCUS parameters in differentiating histopathological responders from non-responders.RESULTS:The study population consisted of 32 men and 11 women,with mean age of 59.7 ± 11.4 years.Neither age,sex,histologic type,tumor site,T stage,nor N stage was associated with pathological response.The responders had significantly smaller mean tumor size than the non-responders(15.7 ± 7.4 cm vs 33.3 ± 14.1 cm,P < 0.01).According to Mandard's criteria,27 patients were classified as responders,with 11(40.7%) showing decreased tumor size by DCUS.In contrast,only three(18.8%) of the 16 non-responders showed decreased tumor size by DCUS(P < 0.01).The area under the ROC curve was 0.64,with a 95%CI of 0.46-0.81.The effects of several cut-off points on diagnostic parameters were calculated in the ROC curve analysis.By maximizing Youden's index(sensitivity + specificity-1),the best cut-off point for distinguishing responders from non-responders was determined,which had optimal sensitivity of 62.9% and specificity of 56.3%.Using this cut-off point,the positive and negative predictive values of DCUS for distinguishing responders from non-responders were 70.8% and 47.4%,respectively.The overall accuracy of DCUS for therapeutic response assessment was 60.5%,slightly higher than the 53.5% for CT response assessment with RECIST criteria(P = 0.663).Although the advantage was not statistically significant,likely due to the small number of cases assessed.DCUS was able to identify decreased perfusion in responders who showed no morphological change by CT imaging,which can be occluded by such treatment effects as fibrosis and edema.CONCLUSION:DCUS may represent an innovative tool for more accurately predicting histopathological response to neoadjuvant chemotherapy before surgical resection in patients with locally-advanced gastric cancer.展开更多
The selective laser melting(SLM)processed aluminum alloys have already aroused researchers’attention in aerospace,rail transport and petrochemical engineering due to the comprehensive advantages of low density,good c...The selective laser melting(SLM)processed aluminum alloys have already aroused researchers’attention in aerospace,rail transport and petrochemical engineering due to the comprehensive advantages of low density,good corrosion resistance and high mechanical performance.In this paper,an Al-14.1Mg-0.47Si-0.31Sc-0.17Zr alloy was fabricated via SLM.The characteristics of single track at different process parameters,and the influence of hatch spacing on densification,microstructural features and tensile properties of block specimens were systematically studied.The hatch spacing has an influence on the overlap ratio of single track,and further affects the internal forming quality of printed specimen.At a laser power of 160 W and scanning speed of 400 mm/s,the densification of block specimen increased first and then decreased with the increase of hatch spacing.The nearly full dense specimen(98.7%)with a tensile strength of 452 MPa was fabricated at a hatch spacing of 80μm.Typical characteristics of dimple and cleavage on the tensile fracture of the AlMgSiScZr alloy showed the mixed fracture of ductility and brittleness.展开更多
AIM:To improve the diagnosis of heterotopic pancreas by the use of contrastenhanced computed tomography(CT)imaging and CT virtual endoscopy(CTVE).METHODS:A total of six patients with heterotopic pancreas,as confirmed ...AIM:To improve the diagnosis of heterotopic pancreas by the use of contrastenhanced computed tomography(CT)imaging and CT virtual endoscopy(CTVE).METHODS:A total of six patients with heterotopic pancreas,as confirmed by clinical pathology and immunohistochemistry in the Sixth Affiliated People's Hospital of Shanghai Jiao Tong University,Shanghai,China,were included.Nonenhanced CT and enhanced CT scanning were performed,and the resulting images were reviewed and analyzed using threedimensional postprocessing software,including CTVE.RESULTS:Four males and two females were enrolled.Several heterotopic pancreas sites were involved;three occurred in the stomach,including the gastric antrum(n =2)and lesser curvature(n=1),and two were in the duodenal bulb.Only one case of heterotopic pancreas lesion occurred in the mesentery.Four cases had a solid yet soft tissue density that had a homogeneous pattern when viewed by enhanced CT.Additionally,their CT values were similar to that of the pancreas.The ducts of the heterotopic pancreas tissue,one of the characteristic CT features of heterotopic pancreas tissue,were detected in the CT images of two patients.CTVE images showed normal mucosa around the tissue,which is also an important indicator of a heterotopic pancreas.However,none of the CTVE images showed the typical signs of central dimpling or umbilication.CONCLUSION:CT,enhanced CT and CTVE techniques provide useful information about the location,growth pattern,vascularity,and condition of the gastrointestinal wall around heterotopic pancreatic tissue.展开更多
Plasma electrolytic oxidation(PEO) was developed as a bond coat for air plasma sprayed(APS) nanostructure ZrO2 as top coat to enhance the corrosion resistance and antibacterial activity of Mg alloy. Corrosion beha...Plasma electrolytic oxidation(PEO) was developed as a bond coat for air plasma sprayed(APS) nanostructure ZrO2 as top coat to enhance the corrosion resistance and antibacterial activity of Mg alloy. Corrosion behavior and antibacterial activities of coated and uncoated samples were assessed by electrochemical tests and agar diffusion method toward Escherichia coli(E. coli) bacterial pathogens, respectively. The lowest corrosion current density and the highest charge transfer resistance, phase angle and impedance modulus were observed for PEO/nano-ZrO2 coated sample compared with those of PEO coated and bare Mg alloys. Nano-ZrO2 top coat which has completely sealed PEO bond coat is able to considerably delay aggressive ions transportation towards Mg alloy surface and significantly enhances corrosion resistance of Mg alloy in simulated body fluid(SBF) solution. Moreover, higher antibacterial activity was also observed in PEO/nano-ZrO2 coating against bacterial strains than that of the PEO coated and bare Mg alloys. This observation was attributed to the presence of ZrO2 nanoparticles which decelerate E. coli growth as a result of E. coli membranes.展开更多
The doping effect of Cu on the self-assembly film of melamine on an Au(111) surface has been investigated with scanning tunneling microscopy (STM). The evaporated Cu adatoms occupy the positions underneath the ami...The doping effect of Cu on the self-assembly film of melamine on an Au(111) surface has been investigated with scanning tunneling microscopy (STM). The evaporated Cu adatoms occupy the positions underneath the amino groups and change the hydrogen bonding pat- tern between the melamine molecules. Accordingly, the self-assembly structure has changed stepwise from a well-defined honeycomb into a track-like and then a triangular structure depending on the amount of Cu adatoms. The interaction between Cu adatom and melamine is moderate thus the Cu adatoms can be released upon mild heating to around 100 ℃. These findings are different from previous observations of either the coordination assembly or the physically trapped metal adatoms.展开更多
Coal and shale are both unconventional gas reservoirs. Comparison of pore characteristics in shale and coal would help understand organic pore structure in shale and investigate co-exploration of shale gas and coalbed...Coal and shale are both unconventional gas reservoirs. Comparison of pore characteristics in shale and coal would help understand organic pore structure in shale and investigate co-exploration of shale gas and coalbed methane in coal bearing strata. In this study, five shale samples and three coal samples of Taiyuan Formation were collected from Qinshui Basin, China. High pressure mercury injection, scanning electronic microscopy, and fractal theory have been used to compare pore characteristics in shale and coal. The results show that pore volumes in coal are much larger than that in shale, especially pores 3-100 nm. In coal, there are many semi-closed pores in micro pores (〈10 nm) and transition pores (10-100 nm). On the contrary, micro pores and transition pores are mainly with open pores in shale. The fractal curves show that pores larger than 65 nm in coal and shale reservoir both have obvious self-similarity and the fractal dimension values in shale and coal are similar. But the fractal characteristics of pores smaller than 65 nm in shale reservoir are quite different from that in coal.展开更多
Carcinoids are tumors derived from neuroendocrine cells and often produce functional peptide hormones.Approximately 54.5% arise in the gastrointestinal tract and frequently metastasize to the liver.Primary hepatic car...Carcinoids are tumors derived from neuroendocrine cells and often produce functional peptide hormones.Approximately 54.5% arise in the gastrointestinal tract and frequently metastasize to the liver.Primary hepatic carcinoid tumors(PHCT) are extremely rare;only 95 cases have been reported.A 65-year-old man came to our attention due to occasional ultrasound findings in absence of clinical manifestations.His previous medical history,since 2003,included an echotomography of the dishomogeneous parenchymal area but no focal lesions.A computed tomography scan performed in 2005 showed an enhanced pseudonodular-like lesion of about 2 cm.Cholangio-magnetic resonance imaging identified the lesion as a possible cholangiocarcinoma.No positive findings were obtained with positron emission tomography.Histology suggested a secondary localization in the liver caused by a low-grade malignant neuroendocrine tumor.Immunohistochemistry was positive for anti chromogranin antibodies,Ki67 antibodies and synaptophysin.Octreoscan scintigraphy indicated intense activity in the lesion.Endoscopic investigations were performed to exclude the presence of extrahepatic neoplasms.Diagnosis of PHCT was established.The patient underwent left hepatectomy,followed by hormone therapy with sandostatine LAR.Two months after surgery he had a lymph nodal relapse along the celiac trunk and caudate lobe,which was histologically confirmed.The postoperative clinical course was uneventful,with a negative follow-up for hematochemical,clinical and radiological investigations at 18 mo post-surgery.Diagnosis of PHCT is based principally on the histopathological confi rmation of a carcinoid tumor and the exclusion of a non-hepatic primary tumor.Surgical resection is the recommended primary treatment for PHCT.Recurrence rate and survival rate in patients treated with resection were 18% and 74%,respectively.展开更多
We have investigated the self-assembly and light emission properties of organic α- sexithiophene (α-6T) molecules on Ag(100) under different coverage by scanning tunneling microscopy (STM). At very low coverag...We have investigated the self-assembly and light emission properties of organic α- sexithiophene (α-6T) molecules on Ag(100) under different coverage by scanning tunneling microscopy (STM). At very low coverage, the α-6T molecules form a unique enantiomer by grouping four molecules into a windmill supermolecular structure. As the coverage is increased,α-6T molecules tend to pack side by side into a denser stripe structure. Further increase of the coverage will lead to the layer-by-layer growth of molecules on Ag(100) with the lower-layer stripe pattern serving as a template. Molecular fluorescence for α-6T molecules on Ag(100) at a coverage of five monolayers has been detected by light excitations, which indicates a well decoupled electronic states for the top-layer α-6T molecules. However, the STM induced luminescent spectra for the same sample reveal only plasmonic-like emission. The absence of intramolecular fluorescence in this case suggests that the electronic decoupling is not a sufficient condition for generating photon emission from molecules. For intramolecular fluorescence to occur, the orientation of the dynamic dipole moment of molecules and the energy-level alignment at the molecule-metal interface are also important so that molecules can be effectively excited through efficient dipolar coupling with local plasmons and by injecting holes into the molecules.展开更多
In this study, we designed and synthesized a novel battery-type electrode featuring three-dimensional(3D) hierarchical ZnO@Ni_xCo_(1-x)(OH)_y core/shell nanowire/nanosheet arrays arranged on Nifoam substrate via a two...In this study, we designed and synthesized a novel battery-type electrode featuring three-dimensional(3D) hierarchical ZnO@Ni_xCo_(1-x)(OH)_y core/shell nanowire/nanosheet arrays arranged on Nifoam substrate via a two-step protocol including a wet chemical process followed by electro-deposition. We then characterized its composition, structure and surface morphology by X-ray diff raction, energy-dispersive X-ray spectrometry(EDS), X-ray photoelectron spectroscopy, scanning electron microscopy(SEM), transmission electron microscopy, EDS elemental mapping. Our electrochemical measurements show that the ZnO@Ni_(0.67)Co_(0.33)(OH)_y electrode material exhibited a noticeably high specific capacity of as much as 255(mA ·h)/g at 1 A/g. Additionally, it demonstrated a superior rate capability, as well as an excellent cycling stability with 81.6% capacity retention over 2000 cycles at 5 A/g. This sample delivered a high energy density of 64 W·h/kg and a power density of 250 W/kg at a current density of 1 A/g. With such remarkable electrochemical properties, we expect the 3D hierarchical hybrid electrode material presented in this work to have promising applications for the next generation of energy storage systems.展开更多
The effects of different yaw angles on the aerodynamic performance of city electric multiple units(EMUs)were investigated in a wind tunnel using a 1:16.8 scaled model.Pressure scanning valve and six-component box-type...The effects of different yaw angles on the aerodynamic performance of city electric multiple units(EMUs)were investigated in a wind tunnel using a 1:16.8 scaled model.Pressure scanning valve and six-component box-type aerodynamic balance were used to test the pressure distribution and aerodynamic force of the head car respectively from the 1.5-and 3-coach grouping city EMU models.Meanwhile,the effects of the yaw angles on the pressure distribution of the streamlined head as well as the aerodynamic forces of the train were analyzed.The experimental results showed that the pressure coefficient was the smallest at the maximum slope of the main shape-line.The side force coefficient and pressure coefficient along the head car cross-section were most affected by crosswind when the yaw angle was 55°,and replacing a 3-coach grouping with a 1.5-coach grouping had obvious advantages for wind tunnel testing when the yaw angle was within 24.2°.In addition,the relative errors of lift coefficient C_(L),roll moment coefficient C_(Mx),side force coefficient C_(S),and drag coefficient C_(D) between the 1.5-and 3-coach cases were below 5.95%,which all met the requirements of the experimental accuracy.展开更多
The effect of thixoforming process on morphologies of silicon particles that affect fracture mode of A356 alloy was investigated.Microstructure and fracture surfaces of thixoformed samples were investigated by image a...The effect of thixoforming process on morphologies of silicon particles that affect fracture mode of A356 alloy was investigated.Microstructure and fracture surfaces of thixoformed samples were investigated by image analyzing technique and scanning electron microscopy.A new combination parameter, called silicon density ratio (SDR) index, was introduced.SDR index approximates the collective effects of morphological characteristics of silicon particles on microstructure transparency of alloy in crossing the dislocation.It is suggested that samples with lower SDR index have superior mechanical properties, especially elongation, and consequently intergranular fracture mode.On the contrary, samples with higher SDR index have inferior mechanical properties and fracture path tends to propagate along the cell boundaries leading to transgranular fracture.展开更多
Micro computed tomography (Micro-CT) was applied to obtain three-dimensional images of the microstructure of cement paste (water-to-cement mass ratio of 0.5) at different ages. By using the Amira software, component p...Micro computed tomography (Micro-CT) was applied to obtain three-dimensional images of the microstructure of cement paste (water-to-cement mass ratio of 0.5) at different ages. By using the Amira software, component phases of the cement paste such as pores, hydration products, and unhydrated clinker particles were segmented from each other based on their 3D image grey levels; their relative contents were also calculated with the software, and the data are 61.2%, 0% and 38.8% at the beginning of hydration and 11.8%, 78.5% and 9.7% at 28 d age, respectively. The hydration degree of cement paste at different ages was compared with the experimental data acquired by loss on ignition (LOI) tests. The results show that the calculated and measured data reasonably agree with each other, which indicates that micro-CT is a useful and reliable approach to characterize the micro structure evolution of hydrating cement paste.展开更多
基金The National Natural Science Foundation of China(No.71071033)the Innovation Project of Jiangsu Postgraduate Education(No.CX10B_058Z)
文摘The integrated linkage control problem based on attack detection is solved with the analyses of the security model including firewall, intrusion detection system (IDS) and vulnerability scan by game theory. The Nash equilibrium for two portfolios of only deploying IDS and vulnerability scan and deploying all the technologies is investigated by backward induction. The results show that when the detection rates of IDS and vulnerability scan are low, the firm will not only inspect every user who raises an alarm, but also a fraction of users that do not raise an alarm; when the detection rates of IDS and vulnerability scan are sufficiently high, the firm will not inspect any user who does not raise an alarm, but only inspect a fraction of users that raise an alarm. Adding firewall into the information system impacts on the benefits of firms and hackers, but does not change the optimal strategies of hackers, and the optimal investigation strategies of IDS are only changed in certain cases. Moreover, the interactions between IDS & vulnerability scan and firewall & IDS are discussed in detail.
文摘We report a rare case of extramedullary plasmocytoma associated with a massive deposit of amyloid in the duodenum. A 72-year-old Japanese man was admitted to our hospital presenting with a 3-mo history of epigastric pain, vomiting and weight loss. On computed tomography (CT) a wall thickening of the fourth part of the duodenum was observed. Multiple biopsies obtained from the lesion showed infiltration of plasma cells and lymphocytes, but they were not conclusive. The patient underwent resection of the lesion and, on histopathological examination, the lesion consisted of a dense and diffuse infiltrate of plasma cells and a few admixed lymphocytes with reactive follicles extending to the muscular propria. An extensive deposition of amyloid was also observed. Immunohistochemical stains revealed that a few plasmacytoid cells showed λ light chain staining, though most were κ: light chain positive. These cells also were positive for CD138 and CD56 but negative for CD20 and CD79. The findings were consistent with extramedullary plasmocytoma associated with a massive deposit of amyloid in duodenum. A subsequent workup for multiple myeloma was completely negative. The patient showed no signs of local recurrence or dissemination of the disease after 12 mo follow-up. Because of the association of plasmocytoma and amyloidosis, the patient must be followed up because of the possible systemic involvement of the neoplasm and amyloidosis in future.
基金Supported by National Science Foundation of China,No. 81101834Projects of the Health Bureau of Zhejiang Province, No.2009QN011 and 2011KYB037
文摘AIM:To quantitatively assess the ability of double contrast-enhanced ultrasound(DCUS) to detect tumor early response to pre-operative chemotherapy.METHODS:Forty-three patients with gastric cancer treated with neoadjuvant chemotherapy followed by curative resection between September 2011 and February 2012 were analyzed.Pre-operative chemotherapy regimens of fluorouracil + oxaliplatin or S-1 + oxaliplatin were administered in 2-4 cycles over 6-12 wk periods.All patients underwent contrast-enhanced computed tomography(CT) scan and DCUS before and after two courses of pre-operative chemotherapy.The therapeutic response was assessed by CT using the response evaluation criteria in solid tumors(RECIST 1.1) criteria.Tumor area was assessed by DCUS as enhanced appearance of gastric carcinoma due to tumor vascularity during the contrast phase as compared to the normal gastric wall.Histopathologic analysis was carried out according to the Mandard tumor regression grade criteria and used as the reference standard.Receiver operating characteristic(ROC) analysis was used to evaluate the efficacy of DCUS parameters in differentiating histopathological responders from non-responders.RESULTS:The study population consisted of 32 men and 11 women,with mean age of 59.7 ± 11.4 years.Neither age,sex,histologic type,tumor site,T stage,nor N stage was associated with pathological response.The responders had significantly smaller mean tumor size than the non-responders(15.7 ± 7.4 cm vs 33.3 ± 14.1 cm,P < 0.01).According to Mandard's criteria,27 patients were classified as responders,with 11(40.7%) showing decreased tumor size by DCUS.In contrast,only three(18.8%) of the 16 non-responders showed decreased tumor size by DCUS(P < 0.01).The area under the ROC curve was 0.64,with a 95%CI of 0.46-0.81.The effects of several cut-off points on diagnostic parameters were calculated in the ROC curve analysis.By maximizing Youden's index(sensitivity + specificity-1),the best cut-off point for distinguishing responders from non-responders was determined,which had optimal sensitivity of 62.9% and specificity of 56.3%.Using this cut-off point,the positive and negative predictive values of DCUS for distinguishing responders from non-responders were 70.8% and 47.4%,respectively.The overall accuracy of DCUS for therapeutic response assessment was 60.5%,slightly higher than the 53.5% for CT response assessment with RECIST criteria(P = 0.663).Although the advantage was not statistically significant,likely due to the small number of cases assessed.DCUS was able to identify decreased perfusion in responders who showed no morphological change by CT imaging,which can be occluded by such treatment effects as fibrosis and edema.CONCLUSION:DCUS may represent an innovative tool for more accurately predicting histopathological response to neoadjuvant chemotherapy before surgical resection in patients with locally-advanced gastric cancer.
基金Project(51775481)supported by the National Natural Science Foundation of ChinaProject(E2019203418)supported by the Natural Science Foundation of Hebei Province,China。
文摘The selective laser melting(SLM)processed aluminum alloys have already aroused researchers’attention in aerospace,rail transport and petrochemical engineering due to the comprehensive advantages of low density,good corrosion resistance and high mechanical performance.In this paper,an Al-14.1Mg-0.47Si-0.31Sc-0.17Zr alloy was fabricated via SLM.The characteristics of single track at different process parameters,and the influence of hatch spacing on densification,microstructural features and tensile properties of block specimens were systematically studied.The hatch spacing has an influence on the overlap ratio of single track,and further affects the internal forming quality of printed specimen.At a laser power of 160 W and scanning speed of 400 mm/s,the densification of block specimen increased first and then decreased with the increase of hatch spacing.The nearly full dense specimen(98.7%)with a tensile strength of 452 MPa was fabricated at a hatch spacing of 80μm.Typical characteristics of dimple and cleavage on the tensile fracture of the AlMgSiScZr alloy showed the mixed fracture of ductility and brittleness.
基金Supported by Science and Technology Commission of Shanghai Municipality,Grant No.08411951200
文摘AIM:To improve the diagnosis of heterotopic pancreas by the use of contrastenhanced computed tomography(CT)imaging and CT virtual endoscopy(CTVE).METHODS:A total of six patients with heterotopic pancreas,as confirmed by clinical pathology and immunohistochemistry in the Sixth Affiliated People's Hospital of Shanghai Jiao Tong University,Shanghai,China,were included.Nonenhanced CT and enhanced CT scanning were performed,and the resulting images were reviewed and analyzed using threedimensional postprocessing software,including CTVE.RESULTS:Four males and two females were enrolled.Several heterotopic pancreas sites were involved;three occurred in the stomach,including the gastric antrum(n =2)and lesser curvature(n=1),and two were in the duodenal bulb.Only one case of heterotopic pancreas lesion occurred in the mesentery.Four cases had a solid yet soft tissue density that had a homogeneous pattern when viewed by enhanced CT.Additionally,their CT values were similar to that of the pancreas.The ducts of the heterotopic pancreas tissue,one of the characteristic CT features of heterotopic pancreas tissue,were detected in the CT images of two patients.CTVE images showed normal mucosa around the tissue,which is also an important indicator of a heterotopic pancreas.However,none of the CTVE images showed the typical signs of central dimpling or umbilication.CONCLUSION:CT,enhanced CT and CTVE techniques provide useful information about the location,growth pattern,vascularity,and condition of the gastrointestinal wall around heterotopic pancreatic tissue.
基金the Universiti Teknologi Malaysia (UTM) for providing research facilities and financial support under Grants No:(1)UTM-Research University Grant (RUG) (Q.J130000.2524.16H35),and (2)Nippon Sheet Glass (NSG) R.J130000.7324.4B300
文摘Plasma electrolytic oxidation(PEO) was developed as a bond coat for air plasma sprayed(APS) nanostructure ZrO2 as top coat to enhance the corrosion resistance and antibacterial activity of Mg alloy. Corrosion behavior and antibacterial activities of coated and uncoated samples were assessed by electrochemical tests and agar diffusion method toward Escherichia coli(E. coli) bacterial pathogens, respectively. The lowest corrosion current density and the highest charge transfer resistance, phase angle and impedance modulus were observed for PEO/nano-ZrO2 coated sample compared with those of PEO coated and bare Mg alloys. Nano-ZrO2 top coat which has completely sealed PEO bond coat is able to considerably delay aggressive ions transportation towards Mg alloy surface and significantly enhances corrosion resistance of Mg alloy in simulated body fluid(SBF) solution. Moreover, higher antibacterial activity was also observed in PEO/nano-ZrO2 coating against bacterial strains than that of the PEO coated and bare Mg alloys. This observation was attributed to the presence of ZrO2 nanoparticles which decelerate E. coli growth as a result of E. coli membranes.
基金This work was supported by the National Natural Science Foundation of China (No.91545128, No.21333001, No.91227117) and Ministry of Science and Technology of China (No.2011CB808702), the Fundamental Research Funds for the Central Universities and the Thousand Talent Program for Young Outstanding Scientists of the Chinese Government, and the "Strategic Priority Research Program" of the Chinese Academy of Sciences (XDB01020100).
文摘The doping effect of Cu on the self-assembly film of melamine on an Au(111) surface has been investigated with scanning tunneling microscopy (STM). The evaporated Cu adatoms occupy the positions underneath the amino groups and change the hydrogen bonding pat- tern between the melamine molecules. Accordingly, the self-assembly structure has changed stepwise from a well-defined honeycomb into a track-like and then a triangular structure depending on the amount of Cu adatoms. The interaction between Cu adatom and melamine is moderate thus the Cu adatoms can be released upon mild heating to around 100 ℃. These findings are different from previous observations of either the coordination assembly or the physically trapped metal adatoms.
基金The authors thank the National Science Foundation of China (41472135), the Research and Innovation Project for College Graduates of Jiangsu Province (KYLX15-1396), the Scientific Research Foundation of the Key Laboratory of Coalbed Methane Resources and Reservoir Formation Process, Ministry of Education (China University of Mining and Technology) (No. 2015-04) for the support of the research.
文摘Coal and shale are both unconventional gas reservoirs. Comparison of pore characteristics in shale and coal would help understand organic pore structure in shale and investigate co-exploration of shale gas and coalbed methane in coal bearing strata. In this study, five shale samples and three coal samples of Taiyuan Formation were collected from Qinshui Basin, China. High pressure mercury injection, scanning electronic microscopy, and fractal theory have been used to compare pore characteristics in shale and coal. The results show that pore volumes in coal are much larger than that in shale, especially pores 3-100 nm. In coal, there are many semi-closed pores in micro pores (〈10 nm) and transition pores (10-100 nm). On the contrary, micro pores and transition pores are mainly with open pores in shale. The fractal curves show that pores larger than 65 nm in coal and shale reservoir both have obvious self-similarity and the fractal dimension values in shale and coal are similar. But the fractal characteristics of pores smaller than 65 nm in shale reservoir are quite different from that in coal.
文摘Carcinoids are tumors derived from neuroendocrine cells and often produce functional peptide hormones.Approximately 54.5% arise in the gastrointestinal tract and frequently metastasize to the liver.Primary hepatic carcinoid tumors(PHCT) are extremely rare;only 95 cases have been reported.A 65-year-old man came to our attention due to occasional ultrasound findings in absence of clinical manifestations.His previous medical history,since 2003,included an echotomography of the dishomogeneous parenchymal area but no focal lesions.A computed tomography scan performed in 2005 showed an enhanced pseudonodular-like lesion of about 2 cm.Cholangio-magnetic resonance imaging identified the lesion as a possible cholangiocarcinoma.No positive findings were obtained with positron emission tomography.Histology suggested a secondary localization in the liver caused by a low-grade malignant neuroendocrine tumor.Immunohistochemistry was positive for anti chromogranin antibodies,Ki67 antibodies and synaptophysin.Octreoscan scintigraphy indicated intense activity in the lesion.Endoscopic investigations were performed to exclude the presence of extrahepatic neoplasms.Diagnosis of PHCT was established.The patient underwent left hepatectomy,followed by hormone therapy with sandostatine LAR.Two months after surgery he had a lymph nodal relapse along the celiac trunk and caudate lobe,which was histologically confirmed.The postoperative clinical course was uneventful,with a negative follow-up for hematochemical,clinical and radiological investigations at 18 mo post-surgery.Diagnosis of PHCT is based principally on the histopathological confi rmation of a carcinoid tumor and the exclusion of a non-hepatic primary tumor.Surgical resection is the recommended primary treatment for PHCT.Recurrence rate and survival rate in patients treated with resection were 18% and 74%,respectively.
基金Author to whom correspondence should be addressed. E-mail: zcdong@ustc.edu.cn, FAX: +86-551-3600103 This work was supported by the National Basic Research Program of China (No.2006CB922003 and No.2011CB921402), the Chinese Academy of Sciences (No.KJCX2.YW.H06), and the National Natural Science Foundation of China (No.91021004, No.10574117, and No.10974186).
文摘We have investigated the self-assembly and light emission properties of organic α- sexithiophene (α-6T) molecules on Ag(100) under different coverage by scanning tunneling microscopy (STM). At very low coverage, the α-6T molecules form a unique enantiomer by grouping four molecules into a windmill supermolecular structure. As the coverage is increased,α-6T molecules tend to pack side by side into a denser stripe structure. Further increase of the coverage will lead to the layer-by-layer growth of molecules on Ag(100) with the lower-layer stripe pattern serving as a template. Molecular fluorescence for α-6T molecules on Ag(100) at a coverage of five monolayers has been detected by light excitations, which indicates a well decoupled electronic states for the top-layer α-6T molecules. However, the STM induced luminescent spectra for the same sample reveal only plasmonic-like emission. The absence of intramolecular fluorescence in this case suggests that the electronic decoupling is not a sufficient condition for generating photon emission from molecules. For intramolecular fluorescence to occur, the orientation of the dynamic dipole moment of molecules and the energy-level alignment at the molecule-metal interface are also important so that molecules can be effectively excited through efficient dipolar coupling with local plasmons and by injecting holes into the molecules.
基金supported by the National Basic Research Program of China ("973" Program, No. 2012CB720302)the National Key Research and Development Program of China (No 2016YFF0102503)
文摘In this study, we designed and synthesized a novel battery-type electrode featuring three-dimensional(3D) hierarchical ZnO@Ni_xCo_(1-x)(OH)_y core/shell nanowire/nanosheet arrays arranged on Nifoam substrate via a two-step protocol including a wet chemical process followed by electro-deposition. We then characterized its composition, structure and surface morphology by X-ray diff raction, energy-dispersive X-ray spectrometry(EDS), X-ray photoelectron spectroscopy, scanning electron microscopy(SEM), transmission electron microscopy, EDS elemental mapping. Our electrochemical measurements show that the ZnO@Ni_(0.67)Co_(0.33)(OH)_y electrode material exhibited a noticeably high specific capacity of as much as 255(mA ·h)/g at 1 A/g. Additionally, it demonstrated a superior rate capability, as well as an excellent cycling stability with 81.6% capacity retention over 2000 cycles at 5 A/g. This sample delivered a high energy density of 64 W·h/kg and a power density of 250 W/kg at a current density of 1 A/g. With such remarkable electrochemical properties, we expect the 3D hierarchical hybrid electrode material presented in this work to have promising applications for the next generation of energy storage systems.
基金Project(2020YFA0710903) supported by the National Key R&D Program of ChinaProjects(2020zzts111, 2020zzts117)supported by the Graduate Student Independent Innovation Project of Central South University,ChinaProject(202037)supported by Transport Department of Hunan Province Technology Innovation Project,China。
文摘The effects of different yaw angles on the aerodynamic performance of city electric multiple units(EMUs)were investigated in a wind tunnel using a 1:16.8 scaled model.Pressure scanning valve and six-component box-type aerodynamic balance were used to test the pressure distribution and aerodynamic force of the head car respectively from the 1.5-and 3-coach grouping city EMU models.Meanwhile,the effects of the yaw angles on the pressure distribution of the streamlined head as well as the aerodynamic forces of the train were analyzed.The experimental results showed that the pressure coefficient was the smallest at the maximum slope of the main shape-line.The side force coefficient and pressure coefficient along the head car cross-section were most affected by crosswind when the yaw angle was 55°,and replacing a 3-coach grouping with a 1.5-coach grouping had obvious advantages for wind tunnel testing when the yaw angle was within 24.2°.In addition,the relative errors of lift coefficient C_(L),roll moment coefficient C_(Mx),side force coefficient C_(S),and drag coefficient C_(D) between the 1.5-and 3-coach cases were below 5.95%,which all met the requirements of the experimental accuracy.
文摘The effect of thixoforming process on morphologies of silicon particles that affect fracture mode of A356 alloy was investigated.Microstructure and fracture surfaces of thixoformed samples were investigated by image analyzing technique and scanning electron microscopy.A new combination parameter, called silicon density ratio (SDR) index, was introduced.SDR index approximates the collective effects of morphological characteristics of silicon particles on microstructure transparency of alloy in crossing the dislocation.It is suggested that samples with lower SDR index have superior mechanical properties, especially elongation, and consequently intergranular fracture mode.On the contrary, samples with higher SDR index have inferior mechanical properties and fracture path tends to propagate along the cell boundaries leading to transgranular fracture.
基金Project(2009CB623201) supported by the National Basic Research Program of ChinaProjects(50902106, 51272193) supported by the National Natural Science Foundation of ChinaProject(NCET-10-0660) supported by New Century Excellent Talents in Universities of China
文摘Micro computed tomography (Micro-CT) was applied to obtain three-dimensional images of the microstructure of cement paste (water-to-cement mass ratio of 0.5) at different ages. By using the Amira software, component phases of the cement paste such as pores, hydration products, and unhydrated clinker particles were segmented from each other based on their 3D image grey levels; their relative contents were also calculated with the software, and the data are 61.2%, 0% and 38.8% at the beginning of hydration and 11.8%, 78.5% and 9.7% at 28 d age, respectively. The hydration degree of cement paste at different ages was compared with the experimental data acquired by loss on ignition (LOI) tests. The results show that the calculated and measured data reasonably agree with each other, which indicates that micro-CT is a useful and reliable approach to characterize the micro structure evolution of hydrating cement paste.