AIM:To evaluate whether total splenic artery embolization(TSAE) for patients with hypersplenism delivers better long-term outcomes than partial splenic embolization(PSE).METHODS:Sixty-one patients with hypersplenism e...AIM:To evaluate whether total splenic artery embolization(TSAE) for patients with hypersplenism delivers better long-term outcomes than partial splenic embolization(PSE).METHODS:Sixty-one patients with hypersplenism eligible for TSAE(n = 27,group A) or PSE(n = 34,group B) were enrolled into the trial,which included clinical and computed tomography follow-up.Data on technical success,length of hospital stay,white blood cell(WBC) and platelet(PLT) counts,splenic volume and complications were collected at 2 wk,6 mo,and 1,2,3,4 years postoperatively.RESULTS:Both TSAE and PSE were technically successful in all patients.Complications were significantly fewer(P = 0.001),and hospital stay significantly shorter(P = 0.007),in group A than in group B.Postprocedure WBC and PLT counts in group A were significantly higher than those in group B from 6 mo to 4 years(P = 0.001),and post-procedure residual splenic volume in group A was significantly less than that observed in group B at 1,2,3 and 4 years post-procedure(P = 0.001).No significant differences were observed in red blood cell counts and liver function parameters between the two groups following the procedure.CONCLUSION:Our results indicate that TSAE for patients with hypersplenism not only delivers a better longterm outcome,but is also associated with lower complication rates and a shorter hospital stay than PSE.展开更多
Objective： The aim of this study was to determine an optimal slice thickness that was efficient in revealing Iobulation of malignant solitary pulmonary nodules （SPNs） on multi-slice spiral computed tomography （MSC...Objective： The aim of this study was to determine an optimal slice thickness that was efficient in revealing Iobulation of malignant solitary pulmonary nodules （SPNs） on multi-slice spiral computed tomography （MSCT） images preliminarily. Methods： Fifty patients with malignant SPNs （diameter -〈 3 cm） underwent multidetector-row computed tomography of the chest in a single-breath-hold technique. The raw data were acquired with a collimation of 0.625 mm. Three sets of contiguous images were reconstructed with 1-, 2-, and 5-ram slice thickness, respectively. The Iobulation sign of SPNs on the computed tomography （CT） images presented in 1-, 2-, and 5-ram slice thickness was compared. Using the 1-mm sections as the gold standard, an optimal slice thickness in revealing Iobulation sign of SPNs was determined. Results： The 1-mm-thick images CT revealed 98 Iobulations （25 with chord distance 〈 1 ram; 30 with chord distance 1-2 ram; 43 with chord distance 〉 2 mm） of 45 malignant SPNs. 18 Iobulations with chord distance 〈 1 mm presented in 2-mm-thick sections were as same as those in I-ram-thick sections. Statistically significant difference in Iobulations number was found between that revealed in 2-ram-thick images and that in I-ram-thick images （P = 0.023 〈 0.05）. 16 Iobulations with chord distance 〈 1 mm presented in 5-mm-thick sections were as same as that in I-ram-thick sections. There was statistically significant difference in Iobulations number between that revealed in 5-mm-thick images and that in I-ram-thick images （P = 0.004 〈 0.05）. The 24 Iobulations with chord distance 1-2 mm presented in 2-ram-thick sections were as same as that in 1-mm-thick sections. No statistically significant difference in Iobulations number were found between that revealed in 2-mm-thick images and that in 1-mm-thick images （P = 0.261 〉 0.05）. 13 Iobulations with chord distance 1-2 mm presented in 5-ram-thick sections were as same as that in 1- mm-thick sections. There was statistically significant difference in Iobulations number between that revealed in 5-ram-thick images and that in I-ram-thick images （P = 0.003 〈 0.05）. 40 Iobulations with chord distance 〉 2 mm presented in 2-ram-thick sections were as same as that in I-ram-thick sections. No statistically significant difference in Iobulations number was found between that revealed in 2-ram-thick images and that in I-ram-thick images （P = 0.631 〉 0.05）. 36 Iobulations with chord distance 〉 2 mm presented in 5-mm-thick sections were as same as that in I-ram-thick sections. There was no statistically significant difference in Iobulations number between that revealed in 5-ram-thick images and that in I-ram-thick images （P = 0.264 〉 0.05）. Conclusion： It is suggested that the use of 1-mm slice thickness is suitable in revealing Iobulations with chord distance 〈 1 ram. A 2-mm slice thickness is suggested to be used in revealing Iobulafions with chord distance 1-2 mm and 5-mm slice thickness to be used in revealing Iobulations with chord distance 〉 2 mm.展开更多
For deep mining engineering, heat transfer of coal mass is a vital factor in the thermal environment of coal mines. In order to study the thermal conduction mechanism, we obtained gray images of coal mass microstructu...For deep mining engineering, heat transfer of coal mass is a vital factor in the thermal environment of coal mines. In order to study the thermal conduction mechanism, we obtained gray images of coal mass microstructure by scanning samples with a digital microscope. With the use of Matlab, these gray images were transformed into binary images, which were then transformed into a corresponding matrix consisting only of the values 0 and 1. According to the calculation method of box-counting dimension, we calculated the fractal dimension of the loose coal to be approximately 1.86. The thermal conductivity expressions of loose coal were derived based on the simulation method of thermal resistance. We calculated the thermal conductivity of loose coal by using a fractal model and compared the calculated values with our experimental data. The results show that the test data show an encourag-ing agreement with the calculated values. Hence fractal theory is a feasible method for studying thermal conductivity of loose coal.展开更多
We introduce a new algebraic approach dealing with the problem of computing the topology of an arrangement of a finite set of real algebraic plane curves presented implicitly. The main achievement of the presented met...We introduce a new algebraic approach dealing with the problem of computing the topology of an arrangement of a finite set of real algebraic plane curves presented implicitly. The main achievement of the presented method is a complete avoidance of irrational numbers that appear when using the sweeping method in the classical way for solving the problem at hand. Therefore, it is worth mentioning that the efficiency of the proposed method is only assured for low-degree curves.展开更多
Objective:Hepatocellular carcinoma (HCC) is among the most common and rapidly increasing cancers in Pakistan.There is currently no standard management for advanced HCC.The aim of the study was to assess response rate ...Objective:Hepatocellular carcinoma (HCC) is among the most common and rapidly increasing cancers in Pakistan.There is currently no standard management for advanced HCC.The aim of the study was to assess response rate and toxicity of concomitant gemcitabine and external radiation therapy (ERT) in locally advanced HCC.Methods:Sixty patients were enrolled.Gemcitabine,70 mg/m2 was given weekly during ERT.ERT was delivered with 60Co beam up to 30.6 Gy,1.8 Gy/fraction.Tumor response was assessed by computed tomography (CT) at eight weeks.Complete and partial response (CR and PR),progressive and stable disease (PD and SD) were assessed.Hematological,gastrointestinal and hepatic toxicities were assessed weekly.Results:No CR was seen.PR,SD and PD were seen in 33%,40% and 27% of patients respectively.Grade 3/4 toxicity for total leukocyte count and platelets was observed in 7% and 27% patients.Grade 3/4 toxicity for liver failure,bilirubin,aspartate aminotransferase,alanine aminotransferase and alkaline phosphatase was seen in 35%,28%,38%,24% and 43% patients respectively.Conclusion:The study showed that concomitant gemcitabine and ERT is a feasible option with moderate toxicity in advanced HCC.展开更多
The drawn copper wires have been analyzed by differential scanning calorimeter(DSC) and a new method, which uses DSC measurements to determine the Johnson-Mehl-Avrami-Kolmogorov(JMAK) exponent via introducing Arrheniu...The drawn copper wires have been analyzed by differential scanning calorimeter(DSC) and a new method, which uses DSC measurements to determine the Johnson-Mehl-Avrami-Kolmogorov(JMAK) exponent via introducing Arrhenius behavior and modifying the baseline of DSC curves, has been proposed. The results show that JMAK exponent and recrystallization activation energy of the drawn copper wires with a strain of 2.77 are about 2.39 and 125 k J/mol, respectively. The line linking the tangency points of DSC curve hypotenuse can be used as the baseline when calculating recrystallization fraction. The JMAK exponent obtained by the DSC method is in a good agreement with that obtained by microhardness measurements. Compared to traditional methods to measure the exponent, the proposed method is faster and less labor intensive.展开更多
This paper proposes the design and research on the high bandwidth linear frequency sweep signal source involved in the readout unit module of the wireless passive pressure sensor in high temperature based on the princ...This paper proposes the design and research on the high bandwidth linear frequency sweep signal source involved in the readout unit module of the wireless passive pressure sensor in high temperature based on the principle of mutual inductance coupling which is applied widely at present. The operating principle of the linear sweep frequency source based on the direct digital frequency synthesis （DDS） technology is introduced, and the implementation method of the hardware circuit and logic sequential control process required in our system has been realized utilizing this technology. Through the experiments under different conditions of the step value, the sweep range and other related design indicators, the influence on the extraction method of resonance frequency information, extraction accuracy, and others during the readout system of the mutual inductance coupling sensor are analyzed and studied. The design of the linear frequency sweep signal source is realized with a resonance frequency change resolution of 6 kHz, a minimum step value of 1 kHz, and a precision of frequency for 0.116 Hz within the sweep width of 1 MHz - 100MHz. Due to the use of the integrated commercial chip, the linear sweep frequency source is made small in size, high working frequency, high resolution and low step values for the readout unit modularized of a higher application value.展开更多
文摘AIM:To evaluate whether total splenic artery embolization(TSAE) for patients with hypersplenism delivers better long-term outcomes than partial splenic embolization(PSE).METHODS:Sixty-one patients with hypersplenism eligible for TSAE(n = 27,group A) or PSE(n = 34,group B) were enrolled into the trial,which included clinical and computed tomography follow-up.Data on technical success,length of hospital stay,white blood cell(WBC) and platelet(PLT) counts,splenic volume and complications were collected at 2 wk,6 mo,and 1,2,3,4 years postoperatively.RESULTS:Both TSAE and PSE were technically successful in all patients.Complications were significantly fewer(P = 0.001),and hospital stay significantly shorter(P = 0.007),in group A than in group B.Postprocedure WBC and PLT counts in group A were significantly higher than those in group B from 6 mo to 4 years(P = 0.001),and post-procedure residual splenic volume in group A was significantly less than that observed in group B at 1,2,3 and 4 years post-procedure(P = 0.001).No significant differences were observed in red blood cell counts and liver function parameters between the two groups following the procedure.CONCLUSION:Our results indicate that TSAE for patients with hypersplenism not only delivers a better longterm outcome,but is also associated with lower complication rates and a shorter hospital stay than PSE.
文摘Objective： The aim of this study was to determine an optimal slice thickness that was efficient in revealing Iobulation of malignant solitary pulmonary nodules （SPNs） on multi-slice spiral computed tomography （MSCT） images preliminarily. Methods： Fifty patients with malignant SPNs （diameter -〈 3 cm） underwent multidetector-row computed tomography of the chest in a single-breath-hold technique. The raw data were acquired with a collimation of 0.625 mm. Three sets of contiguous images were reconstructed with 1-, 2-, and 5-ram slice thickness, respectively. The Iobulation sign of SPNs on the computed tomography （CT） images presented in 1-, 2-, and 5-ram slice thickness was compared. Using the 1-mm sections as the gold standard, an optimal slice thickness in revealing Iobulation sign of SPNs was determined. Results： The 1-mm-thick images CT revealed 98 Iobulations （25 with chord distance 〈 1 ram; 30 with chord distance 1-2 ram; 43 with chord distance 〉 2 mm） of 45 malignant SPNs. 18 Iobulations with chord distance 〈 1 mm presented in 2-mm-thick sections were as same as those in I-ram-thick sections. Statistically significant difference in Iobulations number was found between that revealed in 2-ram-thick images and that in I-ram-thick images （P = 0.023 〈 0.05）. 16 Iobulations with chord distance 〈 1 mm presented in 5-mm-thick sections were as same as that in I-ram-thick sections. There was statistically significant difference in Iobulations number between that revealed in 5-mm-thick images and that in I-ram-thick images （P = 0.004 〈 0.05）. The 24 Iobulations with chord distance 1-2 mm presented in 2-ram-thick sections were as same as that in 1-mm-thick sections. No statistically significant difference in Iobulations number were found between that revealed in 2-mm-thick images and that in 1-mm-thick images （P = 0.261 〉 0.05）. 13 Iobulations with chord distance 1-2 mm presented in 5-ram-thick sections were as same as that in 1- mm-thick sections. There was statistically significant difference in Iobulations number between that revealed in 5-ram-thick images and that in I-ram-thick images （P = 0.003 〈 0.05）. 40 Iobulations with chord distance 〉 2 mm presented in 2-ram-thick sections were as same as that in I-ram-thick sections. No statistically significant difference in Iobulations number was found between that revealed in 2-ram-thick images and that in I-ram-thick images （P = 0.631 〉 0.05）. 36 Iobulations with chord distance 〉 2 mm presented in 5-mm-thick sections were as same as that in I-ram-thick sections. There was no statistically significant difference in Iobulations number between that revealed in 5-ram-thick images and that in I-ram-thick images （P = 0.264 〉 0.05）. Conclusion： It is suggested that the use of 1-mm slice thickness is suitable in revealing Iobulations with chord distance 〈 1 ram. A 2-mm slice thickness is suggested to be used in revealing Iobulafions with chord distance 1-2 mm and 5-mm slice thickness to be used in revealing Iobulations with chord distance 〉 2 mm.
基金support for this study, provided by the National Natural Science Foundation of China (Nos50534040 and 50974117)the Research Fund of the State Key Laboratory of Coal Resources & Mine Safety, CUMT (No07KF10)
文摘For deep mining engineering, heat transfer of coal mass is a vital factor in the thermal environment of coal mines. In order to study the thermal conduction mechanism, we obtained gray images of coal mass microstructure by scanning samples with a digital microscope. With the use of Matlab, these gray images were transformed into binary images, which were then transformed into a corresponding matrix consisting only of the values 0 and 1. According to the calculation method of box-counting dimension, we calculated the fractal dimension of the loose coal to be approximately 1.86. The thermal conductivity expressions of loose coal were derived based on the simulation method of thermal resistance. We calculated the thermal conductivity of loose coal by using a fractal model and compared the calculated values with our experimental data. The results show that the test data show an encourag-ing agreement with the calculated values. Hence fractal theory is a feasible method for studying thermal conductivity of loose coal.
基金Project (No. MTM2005-08690-C02-02) partially supported by the Spanish Ministry of Science and Innovation Grant
文摘We introduce a new algebraic approach dealing with the problem of computing the topology of an arrangement of a finite set of real algebraic plane curves presented implicitly. The main achievement of the presented method is a complete avoidance of irrational numbers that appear when using the sweeping method in the classical way for solving the problem at hand. Therefore, it is worth mentioning that the efficiency of the proposed method is only assured for low-degree curves.
文摘Objective:Hepatocellular carcinoma (HCC) is among the most common and rapidly increasing cancers in Pakistan.There is currently no standard management for advanced HCC.The aim of the study was to assess response rate and toxicity of concomitant gemcitabine and external radiation therapy (ERT) in locally advanced HCC.Methods:Sixty patients were enrolled.Gemcitabine,70 mg/m2 was given weekly during ERT.ERT was delivered with 60Co beam up to 30.6 Gy,1.8 Gy/fraction.Tumor response was assessed by computed tomography (CT) at eight weeks.Complete and partial response (CR and PR),progressive and stable disease (PD and SD) were assessed.Hematological,gastrointestinal and hepatic toxicities were assessed weekly.Results:No CR was seen.PR,SD and PD were seen in 33%,40% and 27% of patients respectively.Grade 3/4 toxicity for total leukocyte count and platelets was observed in 7% and 27% patients.Grade 3/4 toxicity for liver failure,bilirubin,aspartate aminotransferase,alanine aminotransferase and alkaline phosphatase was seen in 35%,28%,38%,24% and 43% patients respectively.Conclusion:The study showed that concomitant gemcitabine and ERT is a feasible option with moderate toxicity in advanced HCC.
基金Projects(51171135,51371132,51471123) supported by the National Natural Science Foundation of ChinaProjects(2012K07-08,2013KJXX-61) supported by Key Science and Technology Program of Shaanxi Province,ChinaProject(2013JC14) supported by the Education Department Foundation of Shaanxi Province,China
文摘The drawn copper wires have been analyzed by differential scanning calorimeter(DSC) and a new method, which uses DSC measurements to determine the Johnson-Mehl-Avrami-Kolmogorov(JMAK) exponent via introducing Arrhenius behavior and modifying the baseline of DSC curves, has been proposed. The results show that JMAK exponent and recrystallization activation energy of the drawn copper wires with a strain of 2.77 are about 2.39 and 125 k J/mol, respectively. The line linking the tangency points of DSC curve hypotenuse can be used as the baseline when calculating recrystallization fraction. The JMAK exponent obtained by the DSC method is in a good agreement with that obtained by microhardness measurements. Compared to traditional methods to measure the exponent, the proposed method is faster and less labor intensive.
文摘This paper proposes the design and research on the high bandwidth linear frequency sweep signal source involved in the readout unit module of the wireless passive pressure sensor in high temperature based on the principle of mutual inductance coupling which is applied widely at present. The operating principle of the linear sweep frequency source based on the direct digital frequency synthesis （DDS） technology is introduced, and the implementation method of the hardware circuit and logic sequential control process required in our system has been realized utilizing this technology. Through the experiments under different conditions of the step value, the sweep range and other related design indicators, the influence on the extraction method of resonance frequency information, extraction accuracy, and others during the readout system of the mutual inductance coupling sensor are analyzed and studied. The design of the linear frequency sweep signal source is realized with a resonance frequency change resolution of 6 kHz, a minimum step value of 1 kHz, and a precision of frequency for 0.116 Hz within the sweep width of 1 MHz - 100MHz. Due to the use of the integrated commercial chip, the linear sweep frequency source is made small in size, high working frequency, high resolution and low step values for the readout unit modularized of a higher application value.
