Microstructure evolution and dislocation configurations in nanostructured Al–Mg alloys processed by high pressure torsion （HPT） were analyzed by transmission electron microscopy （TEM） and high-resolution TEM （HR...Microstructure evolution and dislocation configurations in nanostructured Al–Mg alloys processed by high pressure torsion （HPT） were analyzed by transmission electron microscopy （TEM） and high-resolution TEM （HRTEM）. The results show that the grains less than 100 nm have sharp grain boundaries （GBs） and are completely free of dislocations. In contrast, a high density of dislocation as high as 1017 m^-2 exists within the grains larger than 200 nm and these larger grains are usually separated into subgrains and dislocation cells. The dislocations are 60° full dislocations with Burgers vectors of 1/2〈110〉and most of them appear as dipoles and loops. The microtwins and stacking faults （SFs） formed by the Shockley partials from the dissociation of both the 60° mixed dislocation and 0° screw dislocation in ultrafine grains were simultaneously observed by HRTEM in the HPT Al–Mg alloys. These results suggest that partial dislocation emissions, as well as the activation of partial dislocations could also become a deformation mechanism in ultrafine-grained aluminum during severe plastic deformation. The grain refinement mechanism associated with the very high local dislocation density, the dislocation cells and the non-equilibrium GBs, as well as the SFs and microtwins in the HPT Al-Mg alloys were proposed.展开更多
Novel 2×2 torsion-mirror optical switch arrays are fabricated by using the mixed micromachining based on the surface and bulk silicon microelectronics,then are investigated electromechanically in applied direct a...Novel 2×2 torsion-mirror optical switch arrays are fabricated by using the mixed micromachining based on the surface and bulk silicon microelectronics,then are investigated electromechanically in applied direct and alternating electric fields.When the thickness of the elastic torsion beams suspending the aluminum coated polysilicon micro-mirrors of the switches in the arrays is about 1μm,the electrostatic yielding voltages for driving the mirrors to achieve their ON-state are in the range of 270～290V,and the minimum holding voltages for mirrors ON-state are found as 55V or so.Theoretical analysis manifests that the yielding voltage is more sensitive to beam thickness than other design parameters do about the torsion-mirror switch structures.The lifetime can reach 10 8 times.The estimated shortest switching time of the switches at least lasts for less than 2ms.The force analysis on the two kinds of new fiber self-holding structures integrated monolithically in the chip of the optical switch arrays indicates that the structures can feature self-fixing and self-aligning of optical fibers.展开更多
With the many changes that have taken place in people＇s diet and lifestyle, colorectal cancer （CRC） has become a global concern. There were approximately 950000 new cases diagnosed and 500000 deaths recorded worldw...With the many changes that have taken place in people＇s diet and lifestyle, colorectal cancer （CRC） has become a global concern. There were approximately 950000 new cases diagnosed and 500000 deaths recorded worldwide in 2000. It is the second most common type of cancer in the Western world, and it is the third most common type of digestive tumor in China. It is reported that the morbidity of CRC is 4.08/100000 for men and 3.30/100000 for women in China. Despite the rate of improvements in surgery, radiotherapy and chemotherapy, the overall five-year survival is around 50%. Therefore, novel treatment need to be developed in order to add to the therapeutic armamentarium. RNA interference （RNAi） is a sequence-specific posttranscriptional gene silencing mechanism, which is triggered by double-stranded RNA （dsRNA） and causes degradation of mRNA homologous in sequence to the dsRNA.This new approach has been successfully adopted to inhibit virus replication and tumorigenicity. Recent reports have described DNA vector-based strategies for delivery of small interfering RNA （siRNA） into mammalian cells, further expanding the utility of RNAi. With the development of the RNAi technology and deeper understanding of this field, a promising new modality of treatment appeared, which can be used in combination with the existing therapies .We reviewed the proceedings on the actualities and advancement of RNAi technology for colorectal cancer therapeutics.展开更多
We report a case of surgically proved left-sided torsion of the greater omentum that caused secondary by untreated inguinal hernia. Case A 36-year-old man presented to our hospital with abdominal pain. He had been dia...We report a case of surgically proved left-sided torsion of the greater omentum that caused secondary by untreated inguinal hernia. Case A 36-year-old man presented to our hospital with abdominal pain. He had been diagnosed with a left inguinal hernia, but he had not received any treatments. Contrast-enhanced computed tomography （CT） of the abdomen showed a large fat density mass below the Sigmoid colon and left inguinal hernia with incarcerated fat. Exploratory laparotomy revealed torsion of the greater omentum with small bloody ascites. The greater omentum was twisted into one and a half circles and entered into a left inguinal hernia. An omentectomy with a repair of left inguinal hernia was performed. A resected omentum was submitted for pathological examination, which showed hemorrhagic infarction. Omental torsion is a rare cause of acute abdominal pain but should be included in the differential diagnoses of acute abdomen, especially in patients with untreated inguinal hernia.展开更多
Left-sided periappendiceal abscesses occur in association with two types of congenital anomaly: intestinal malrotation and situs inversus. It is diffi cult to obtain an accurate preoperative diagnosis of these abscess...Left-sided periappendiceal abscesses occur in association with two types of congenital anomaly: intestinal malrotation and situs inversus. It is diffi cult to obtain an accurate preoperative diagnosis of these abscesses due to the abnormal position of the appendix. We present an unusual case of a left-sided periappendiceal abscess in an adult with intestinal malrotation, the diagnosis of which was a challenge.展开更多
Due to the coaxial connection of engine, motor and pump, the dynamic characteristics of hybrid construction machinery are changed, which generates a new torsional vibration problem of multi-power sources. To reduce th...Due to the coaxial connection of engine, motor and pump, the dynamic characteristics of hybrid construction machinery are changed, which generates a new torsional vibration problem of multi-power sources. To reduce the torsional vibration of the hybrid construction machinery complex shafting, torsional vibration active control was proposed. The three-mass model of coaxial shafting of hybrid construction machinery was established. The PID control and the fuzzy sliding mode control were chosen to weaken torsional vibration by controlling the motor speed and torque. The simulation results show that the fuzzy sliding mode control has 12% overshoot of the PID control when the engine torque changes. The active control is effective and can realize smooth power switch.展开更多
This paper focuses on the state space modeling approach and output torques prediction of torsional vibrations for variable speed wind turbines. The multi-body system model under study is mainly comprised of a wind tur...This paper focuses on the state space modeling approach and output torques prediction of torsional vibrations for variable speed wind turbines. The multi-body system model under study is mainly comprised of a wind turbine, a three stage planetary gear box and an induction generator. The masses-springs approach of shaft system differential equations is developed from Newton＇s law and Lagrange formulas. For an easy comprehension for electrical engineers and tutorial purpose, an electrical equivalent circuit of the system is proposed by using mechanical and electrical components similarities. Extensive numerical simulations are performed to investigate system mechanical resonances and impacts of damping factors on the system dynamic and stability.展开更多
The hydraulic roll-bending device was studied, which was widely used in modem cold rolling mills to regulate the strip flatness. The loaded roll gap crown mathematic model and the strip crown mathematic model of the r...The hydraulic roll-bending device was studied, which was widely used in modem cold rolling mills to regulate the strip flatness. The loaded roll gap crown mathematic model and the strip crown mathematic model of the reversing cold rolling process were established, and the deformation model of roll stack system of the 6-high 1 250 mm high crown （HC） reversing cold rolling mill was built by slit beam method. The simulation results show that, the quadratic component of strip crown decreases nearly linearly with the increase of the work roll bending force, when the shifting value of intermediate roll is determined by the rolling process. From the first pass to the fifth pass of reversing rolling process, the crown controllability of bending force is gradually weakened. Base on analyzing the relationship among the main factors associated with roll-bending force in reversing multi-pass rolling, such as strip width and rolling force, a preset mathematic model of bending force is developed by genetic algorithm. The simulation data demonstrate that the relative deviation of flatness criterions in each rolling pass is improved significantly and the mean relative deviation of all five passes is decreased from 25.1% to 1.7%. The model can keep good shape in multi-pass reversing cold rolling process with the high prediction accuracy and can be used to guide the production process.展开更多
In this study, it shows how the main indicators of torsional vibrations of the crankshaft change when its materials change. In the study, the crankshaft of diesel engine with four cylinders in line was taken, in which...In this study, it shows how the main indicators of torsional vibrations of the crankshaft change when its materials change. In the study, the crankshaft of diesel engine with four cylinders in line was taken, in which the material is changing from steel to cast iron, due to the technological possibilities of production. For study of torsional vibration of crankshaft system, the construction of equivalent reduced scheme is carried. Reduced inertia moments of discs are determined for each crank of crankshaft, by receiving the impact of piston group and rod mass. Reduced rigidities of crank are determined by experimental method. The results show that the rigidity of crank for the same crankshaft varies up to 6%, while the change between crankshafts goes up 10%. At the end, frequency and vibration forms are calculated using Tole-Holxer method. From calculations, it results that the frequencies are 19% smaller, while the vibration forms varies slightly. In this case, the change of the materials leads to the first frequency in the area of engine rotations and it can worsen the level of torsional vibration, therefore, it should check the resonance areas and vibration amplitude.展开更多
An algorithm for computing the 3-D oscillating flow field of the blade passage under the torsional vibra-tion of the rotor is applied to analyze the stability in turbomachines. The induced fiow field responding to bla...An algorithm for computing the 3-D oscillating flow field of the blade passage under the torsional vibra-tion of the rotor is applied to analyze the stability in turbomachines. The induced fiow field responding to blade vibration is computed by Oscillating Fluid Mechanics Method and ParaInetric Polynomial Method. After getting the solution of the unsteady flow field, the work done by the unsteay aerody natnic force acting on the blade can be obtained. The negative or positive work is the criterion of the aeroelastic stability Numerical results indicate that there are instabilities of the torsional vibration in some boency bands.展开更多
基金Project(BK2012715)supported by the Basic Research Program(Natural Science Foundation)of Jiangsu Province,ChinaProject(14KJA430002)supported by the Key University Science Research Project of Jiangsu Province,China+3 种基金Project(50971087)supported by the National Natural Science Foundation of China,ChinaProjects(11JDG070,11JDG140)supported by the Senior Talent Research Foundation of Jiangsu University,ChinaProject(hsm1301)supported by the Foundation of the Jiangsu Province Key Laboratory of High-end Structural Materials,ChinaProject(Kjsmcx2011004)supported by the Foundation of the Jiangsu Province Key Laboratory of Materials Tribology,China
文摘Microstructure evolution and dislocation configurations in nanostructured Al–Mg alloys processed by high pressure torsion （HPT） were analyzed by transmission electron microscopy （TEM） and high-resolution TEM （HRTEM）. The results show that the grains less than 100 nm have sharp grain boundaries （GBs） and are completely free of dislocations. In contrast, a high density of dislocation as high as 1017 m^-2 exists within the grains larger than 200 nm and these larger grains are usually separated into subgrains and dislocation cells. The dislocations are 60° full dislocations with Burgers vectors of 1/2〈110〉and most of them appear as dipoles and loops. The microtwins and stacking faults （SFs） formed by the Shockley partials from the dissociation of both the 60° mixed dislocation and 0° screw dislocation in ultrafine grains were simultaneously observed by HRTEM in the HPT Al–Mg alloys. These results suggest that partial dislocation emissions, as well as the activation of partial dislocations could also become a deformation mechanism in ultrafine-grained aluminum during severe plastic deformation. The grain refinement mechanism associated with the very high local dislocation density, the dislocation cells and the non-equilibrium GBs, as well as the SFs and microtwins in the HPT Al-Mg alloys were proposed.
文摘Novel 2×2 torsion-mirror optical switch arrays are fabricated by using the mixed micromachining based on the surface and bulk silicon microelectronics,then are investigated electromechanically in applied direct and alternating electric fields.When the thickness of the elastic torsion beams suspending the aluminum coated polysilicon micro-mirrors of the switches in the arrays is about 1μm,the electrostatic yielding voltages for driving the mirrors to achieve their ON-state are in the range of 270～290V,and the minimum holding voltages for mirrors ON-state are found as 55V or so.Theoretical analysis manifests that the yielding voltage is more sensitive to beam thickness than other design parameters do about the torsion-mirror switch structures.The lifetime can reach 10 8 times.The estimated shortest switching time of the switches at least lasts for less than 2ms.The force analysis on the two kinds of new fiber self-holding structures integrated monolithically in the chip of the optical switch arrays indicates that the structures can feature self-fixing and self-aligning of optical fibers.
文摘With the many changes that have taken place in people＇s diet and lifestyle, colorectal cancer （CRC） has become a global concern. There were approximately 950000 new cases diagnosed and 500000 deaths recorded worldwide in 2000. It is the second most common type of cancer in the Western world, and it is the third most common type of digestive tumor in China. It is reported that the morbidity of CRC is 4.08/100000 for men and 3.30/100000 for women in China. Despite the rate of improvements in surgery, radiotherapy and chemotherapy, the overall five-year survival is around 50%. Therefore, novel treatment need to be developed in order to add to the therapeutic armamentarium. RNA interference （RNAi） is a sequence-specific posttranscriptional gene silencing mechanism, which is triggered by double-stranded RNA （dsRNA） and causes degradation of mRNA homologous in sequence to the dsRNA.This new approach has been successfully adopted to inhibit virus replication and tumorigenicity. Recent reports have described DNA vector-based strategies for delivery of small interfering RNA （siRNA） into mammalian cells, further expanding the utility of RNAi. With the development of the RNAi technology and deeper understanding of this field, a promising new modality of treatment appeared, which can be used in combination with the existing therapies .We reviewed the proceedings on the actualities and advancement of RNAi technology for colorectal cancer therapeutics.
文摘We report a case of surgically proved left-sided torsion of the greater omentum that caused secondary by untreated inguinal hernia. Case A 36-year-old man presented to our hospital with abdominal pain. He had been diagnosed with a left inguinal hernia, but he had not received any treatments. Contrast-enhanced computed tomography （CT） of the abdomen showed a large fat density mass below the Sigmoid colon and left inguinal hernia with incarcerated fat. Exploratory laparotomy revealed torsion of the greater omentum with small bloody ascites. The greater omentum was twisted into one and a half circles and entered into a left inguinal hernia. An omentectomy with a repair of left inguinal hernia was performed. A resected omentum was submitted for pathological examination, which showed hemorrhagic infarction. Omental torsion is a rare cause of acute abdominal pain but should be included in the differential diagnoses of acute abdomen, especially in patients with untreated inguinal hernia.
文摘Left-sided periappendiceal abscesses occur in association with two types of congenital anomaly: intestinal malrotation and situs inversus. It is diffi cult to obtain an accurate preoperative diagnosis of these abscesses due to the abnormal position of the appendix. We present an unusual case of a left-sided periappendiceal abscess in an adult with intestinal malrotation, the diagnosis of which was a challenge.
基金Project(51205415)supported by the National Natural Science Foundation of ChinaProject(14JJ3020)supported by the Natural Science Foundation of Hunan Province,China+2 种基金Project(2013M542129)supported by China Postdoctoral Science FoundationProject(2012QNZT014)supported by the Fundamental Research Funds for the Central Universities,ChinaProject supported by the Postdoctoral Foundation of Central South University,China
文摘Due to the coaxial connection of engine, motor and pump, the dynamic characteristics of hybrid construction machinery are changed, which generates a new torsional vibration problem of multi-power sources. To reduce the torsional vibration of the hybrid construction machinery complex shafting, torsional vibration active control was proposed. The three-mass model of coaxial shafting of hybrid construction machinery was established. The PID control and the fuzzy sliding mode control were chosen to weaken torsional vibration by controlling the motor speed and torque. The simulation results show that the fuzzy sliding mode control has 12% overshoot of the PID control when the engine torque changes. The active control is effective and can realize smooth power switch.
文摘This paper focuses on the state space modeling approach and output torques prediction of torsional vibrations for variable speed wind turbines. The multi-body system model under study is mainly comprised of a wind turbine, a three stage planetary gear box and an induction generator. The masses-springs approach of shaft system differential equations is developed from Newton＇s law and Lagrange formulas. For an easy comprehension for electrical engineers and tutorial purpose, an electrical equivalent circuit of the system is proposed by using mechanical and electrical components similarities. Extensive numerical simulations are performed to investigate system mechanical resonances and impacts of damping factors on the system dynamic and stability.
基金Project(20050311890) supported by the Science and Technology Development Foundation of University of Science and Technology Beijing,China
文摘The hydraulic roll-bending device was studied, which was widely used in modem cold rolling mills to regulate the strip flatness. The loaded roll gap crown mathematic model and the strip crown mathematic model of the reversing cold rolling process were established, and the deformation model of roll stack system of the 6-high 1 250 mm high crown （HC） reversing cold rolling mill was built by slit beam method. The simulation results show that, the quadratic component of strip crown decreases nearly linearly with the increase of the work roll bending force, when the shifting value of intermediate roll is determined by the rolling process. From the first pass to the fifth pass of reversing rolling process, the crown controllability of bending force is gradually weakened. Base on analyzing the relationship among the main factors associated with roll-bending force in reversing multi-pass rolling, such as strip width and rolling force, a preset mathematic model of bending force is developed by genetic algorithm. The simulation data demonstrate that the relative deviation of flatness criterions in each rolling pass is improved significantly and the mean relative deviation of all five passes is decreased from 25.1% to 1.7%. The model can keep good shape in multi-pass reversing cold rolling process with the high prediction accuracy and can be used to guide the production process.
文摘In this study, it shows how the main indicators of torsional vibrations of the crankshaft change when its materials change. In the study, the crankshaft of diesel engine with four cylinders in line was taken, in which the material is changing from steel to cast iron, due to the technological possibilities of production. For study of torsional vibration of crankshaft system, the construction of equivalent reduced scheme is carried. Reduced inertia moments of discs are determined for each crank of crankshaft, by receiving the impact of piston group and rod mass. Reduced rigidities of crank are determined by experimental method. The results show that the rigidity of crank for the same crankshaft varies up to 6%, while the change between crankshafts goes up 10%. At the end, frequency and vibration forms are calculated using Tole-Holxer method. From calculations, it results that the frequencies are 19% smaller, while the vibration forms varies slightly. In this case, the change of the materials leads to the first frequency in the area of engine rotations and it can worsen the level of torsional vibration, therefore, it should check the resonance areas and vibration amplitude.
文摘An algorithm for computing the 3-D oscillating flow field of the blade passage under the torsional vibra-tion of the rotor is applied to analyze the stability in turbomachines. The induced fiow field responding to blade vibration is computed by Oscillating Fluid Mechanics Method and ParaInetric Polynomial Method. After getting the solution of the unsteady flow field, the work done by the unsteay aerody natnic force acting on the blade can be obtained. The negative or positive work is the criterion of the aeroelastic stability Numerical results indicate that there are instabilities of the torsional vibration in some boency bands.
