Recent technological advances in miniaturization have allowed for a confocal scanning microscope to be integrated into a conventional flexible endoscope,or into trans-endoscopic probes,a technique now known as confoca...Recent technological advances in miniaturization have allowed for a confocal scanning microscope to be integrated into a conventional flexible endoscope,or into trans-endoscopic probes,a technique now known as confocal endomicroscopy or confocal laser endomicroscopy.This newly-developed technology has enabled endoscopists to collect real-time in vivo histological images or "virtual biopsies" of the gastrointestinal mucosa during endoscopy,and has stimulated significant interest in the application of this technique in clinical gastroenterology.This review aims to evaluate the current data on the technical aspects and the utility of this new technology in clinical gastroenterology and its potential impact in the future,particularly in the screening or surveillance of gastrointestinal neoplasia.展开更多
A straightforward technique has been developed to quickly determine the wall contour of super/hypersonic nozzles working at multiply Mach number which share a common throat section.Mach number distribution along the c...A straightforward technique has been developed to quickly determine the wall contour of super/hypersonic nozzles working at multiply Mach number which share a common throat section.Mach number distribution along the centerline of the nozzle is specified in advance and divided into two sections,both of which are described by the b-spline function.The first section is shared by different exit Mach number nozzles.The nozzle contour is determined by the method of characteristics plus boundary layer correction.An example of this design method is employed to illustrate the technique with a computational fluid dynamics calculation.The simulation results indicate that desired Mach numbers are obtained at the nozzle exit,and the good flow quality is attained for different nozzles within δMa/Ma<±0.56% in the flow core region.This technique improves the design precision of the converging-diverging nozzle,cancels waves completely,and achieves nozzles with multiple Mach number exiting which share a common throat section.展开更多
文摘Recent technological advances in miniaturization have allowed for a confocal scanning microscope to be integrated into a conventional flexible endoscope,or into trans-endoscopic probes,a technique now known as confocal endomicroscopy or confocal laser endomicroscopy.This newly-developed technology has enabled endoscopists to collect real-time in vivo histological images or "virtual biopsies" of the gastrointestinal mucosa during endoscopy,and has stimulated significant interest in the application of this technique in clinical gastroenterology.This review aims to evaluate the current data on the technical aspects and the utility of this new technology in clinical gastroenterology and its potential impact in the future,particularly in the screening or surveillance of gastrointestinal neoplasia.
基金Project(11072264) supported by the National Natural Science Foundation of China
文摘A straightforward technique has been developed to quickly determine the wall contour of super/hypersonic nozzles working at multiply Mach number which share a common throat section.Mach number distribution along the centerline of the nozzle is specified in advance and divided into two sections,both of which are described by the b-spline function.The first section is shared by different exit Mach number nozzles.The nozzle contour is determined by the method of characteristics plus boundary layer correction.An example of this design method is employed to illustrate the technique with a computational fluid dynamics calculation.The simulation results indicate that desired Mach numbers are obtained at the nozzle exit,and the good flow quality is attained for different nozzles within δMa/Ma<±0.56% in the flow core region.This technique improves the design precision of the converging-diverging nozzle,cancels waves completely,and achieves nozzles with multiple Mach number exiting which share a common throat section.
