AIM:To investigate the mucosal morphology in Barrett's oesophagus by chromo and magnifying endoscopy.METHODS:A prospective pilot study at a tertiary medical centre was conducted to evaluate the use of acetic acid ...AIM:To investigate the mucosal morphology in Barrett's oesophagus by chromo and magnifying endoscopy.METHODS:A prospective pilot study at a tertiary medical centre was conducted to evaluate the use of acetic acid pulverisation combined with virtual chromoendoscopy using Fujinon intelligent chromoendoscopy(FICE) for semiological characterization of the mucosal morphology in Barrett's oesophagus and its neoplastic complications.Upper endoscopy using high definition whitelight,2% acid acetic pulverisation and FICE with high definition videoendoscopy were performed in 20 patients including 18 patients who presented with aspects of Barrett's oesophagus at endoscopy examination.Two patients used as controls had normal endoscopy and histological results.Prospectively,videos were watched blind from histological results by three trained FICE technique endoscopists.RESULTS:The videos of patients with high-grade dysplasia showed an irregular mucosal pattern in 14% using high definition white light endoscopy and in 100% using acid acetic-FICE combined.Videos did not identify irregular vascular patterns using high definition white light endoscopy,while acid acetic-FICE combined visualised one in 86% of cases.CONCLUSION:Combined acetic acid and FICE is a promising method for screening high-grade dysplasia and early cancer in Barrett's oesophagus.展开更多
The local defect in rotating machine always gives rise to repetitive transients in the collected vibration signal. However, the transient signature is prone to be contaminated by strong background noises, thus it is a...The local defect in rotating machine always gives rise to repetitive transients in the collected vibration signal. However, the transient signature is prone to be contaminated by strong background noises, thus it is a challenging task to detect the weak transients for machine fault diagnosis. In this paper, a novel adaptive tunable Q-factor wavelet transform(TQWT) filter based feature extraction method is proposed to detect repetitive transients. The emerging TQWT possesses distinct advantages over the classical constant-Q wavelet transforms, whose Q-factor can be tuned to match the oscillatory behavior of different signals, but the parameter selection for TQWT heavily relies on prior knowledge. Within our adaptive TQWT filter algorithm, the automatic optimization techniques for three TQWT parameters are implemented to achieve an optimal TQWT basis that matches the transient components. Specifically, the decomposition level is selected according to a center frequency ratio based stopping criterion, and the Q-factor and redundancy are optimized based on the minimum energy-weighted normalized wavelet entropy.Then, the adaptive TQWT decomposition can be achieved in a sparse way and result in subband signals at various wavelet scales.Further, the optimum subband signal which carries transient feature information, is identified using a normalized energy to bandwidth ratio index. Finally, the single branch reconstruction signal from the optimum subband is obtained with transient signatures via inverse TQWT, and the frequency of repetitive transients is detected using Hilbert envelope demodulation. It has been verified via numerical simulation that the proposed adaptive TQWT filter based feature extraction method can adaptively select TQWT parameters and the optimum subband for repetitive transient detection without prior knowledge. The proposed method is also applied to faulty bearing vibration signals and its effectiveness is validated.展开更多
文摘AIM:To investigate the mucosal morphology in Barrett's oesophagus by chromo and magnifying endoscopy.METHODS:A prospective pilot study at a tertiary medical centre was conducted to evaluate the use of acetic acid pulverisation combined with virtual chromoendoscopy using Fujinon intelligent chromoendoscopy(FICE) for semiological characterization of the mucosal morphology in Barrett's oesophagus and its neoplastic complications.Upper endoscopy using high definition whitelight,2% acid acetic pulverisation and FICE with high definition videoendoscopy were performed in 20 patients including 18 patients who presented with aspects of Barrett's oesophagus at endoscopy examination.Two patients used as controls had normal endoscopy and histological results.Prospectively,videos were watched blind from histological results by three trained FICE technique endoscopists.RESULTS:The videos of patients with high-grade dysplasia showed an irregular mucosal pattern in 14% using high definition white light endoscopy and in 100% using acid acetic-FICE combined.Videos did not identify irregular vascular patterns using high definition white light endoscopy,while acid acetic-FICE combined visualised one in 86% of cases.CONCLUSION:Combined acetic acid and FICE is a promising method for screening high-grade dysplasia and early cancer in Barrett's oesophagus.
基金supported by the National Natural Science Foundation of China (Grant Nos. 51335006 & 51605244)
文摘The local defect in rotating machine always gives rise to repetitive transients in the collected vibration signal. However, the transient signature is prone to be contaminated by strong background noises, thus it is a challenging task to detect the weak transients for machine fault diagnosis. In this paper, a novel adaptive tunable Q-factor wavelet transform(TQWT) filter based feature extraction method is proposed to detect repetitive transients. The emerging TQWT possesses distinct advantages over the classical constant-Q wavelet transforms, whose Q-factor can be tuned to match the oscillatory behavior of different signals, but the parameter selection for TQWT heavily relies on prior knowledge. Within our adaptive TQWT filter algorithm, the automatic optimization techniques for three TQWT parameters are implemented to achieve an optimal TQWT basis that matches the transient components. Specifically, the decomposition level is selected according to a center frequency ratio based stopping criterion, and the Q-factor and redundancy are optimized based on the minimum energy-weighted normalized wavelet entropy.Then, the adaptive TQWT decomposition can be achieved in a sparse way and result in subband signals at various wavelet scales.Further, the optimum subband signal which carries transient feature information, is identified using a normalized energy to bandwidth ratio index. Finally, the single branch reconstruction signal from the optimum subband is obtained with transient signatures via inverse TQWT, and the frequency of repetitive transients is detected using Hilbert envelope demodulation. It has been verified via numerical simulation that the proposed adaptive TQWT filter based feature extraction method can adaptively select TQWT parameters and the optimum subband for repetitive transient detection without prior knowledge. The proposed method is also applied to faulty bearing vibration signals and its effectiveness is validated.
