基于Ⅲ级着陆标准的飞机抗偏流机动控制律设计与仿真

针对国际民航组织(ICAO)规定的Ⅲ级气象条件下飞机的自动着陆要求,在某型飞机自动着陆侧向控制系统的基础上,主要兼顾航迹跟踪精度和鲁棒性要求,设计了飞机自动着陆过程中抗偏流机动控制律。利用Matlab/Simulink建立所设计的自动着陆系统动态数学模型并进行仿真,同时对控制系统的稳定性和控制精度进行分析。仿真结果与分析表明,抗偏流机动控制律的设计使接地时的偏流角满足Ⅲ级着陆标准的技术要求,研究成果为获得该类运行的批准提供了重要参考。

图像序列的准三维运动目标自寻的跟踪算法

根据序列图像中的运动目标特征像点必须要满足在像平面里的约束条件,又要满足其空间三维运动规律,导出一套准三维运动模型。进而建立了连续非线性的系统动态模型和离散线性的量测模型,得到一套准三维自动寻的跟踪处理算法,利用二维观测结果就可以实现三维形式的智能跟踪。算法简单,易于实现,而且同样具有三维智能跟踪的优良特点,即抗丢失、抗机动和抗噪扰的鲁棒性能。模拟和真实图像序列的实验结果充分证明了该算法的优良性能。

基于经典控制理论的制导系统校正方法研究

针对空空导弹抗目标大机动时,制导系统持续增加的快速性需求,利用反馈/前馈控制信号可提高瞬态和频率响应的经典控制思想,以及在制导算法中引入导弹的实际加速度补偿量以改善制导回路性能的方法,设计了制导系统校正算法。然后,通过线性化模型对制导系统校正算法的性能进行了数字仿真,仿真结果表明系统校正算法能够降低目标机动时所产生的脱靶量。最后,在仿真环境中加入导引头测角噪声,对校正算法增加前后的制导控制系统性能进行仿真和对比分析,基于分析结果对噪声环境下的校正算法进行了优化。

Impedance force control for position controlled robotic manipulators under the constraint of unknown environments

A force control strategy for position controlled robotic manipulators is presented. On line force feedback data are employed to estimate the local shape of the unknown constraint. The estimated vectors are used to generate the virtual reference trajectory for the target impedance model that is driven by the force error to produce command position. By following the command position trajectory the robotic manipulator can follow the unknown constraint surface while keeping an acceptable force error in a manner depicted by the target impedance model. Computer simulation on a 3 linked planar manipulator and experimental studies on an Adept 3, an SCARA type robotic manipulator, are conducted to verify the force tracking capability of the proposed control strategy.

INFLUENCE OF AIRCRAFT DEICER ON FREEZE-THAW DURABILITY OF HIGH PERFORMANCE CONCRETE

The influence of glycol,the main composition of the most frequently used aircraft dicer,on the freeze-thaw durability of high performance concrete（HPC）is investigated.Freeze-thaw durability of HPC is tested by accelerated freeze-thaw test.Four kinds of the solution,i.e.,tap water,3.5% NaCl solution,glycol solutions,and a LBR-A type commercial aircraft deicer are employed.Results show that freeze-thaw durability of HPC exposed to glycol solutions is closely related to the solution concentrations.The failure of HPC exposed to 3.5% glycol solution is similar to that of those exposed to 3.5% NaCl solution,i.e.,serious surface scaling.While the damage of HPC exposed to 12.5%—25% glycol solutions is postponed.Compared with glycol solution,the commercial aircraft deicer has much more negative effects on HPC freeze-thaw durability compared with 3.5% NaCl solution.In the presence of commercial aircraft deicer for HPC subjected to freeze-thaw cycles,the deterioration is mainly due to scaling and spalling.

Setting up the Model of Xeno-graft Verse Host Disease

Objective: To observe human to mouse one way mixed lymphocyte(MLC); And to set up the xeno-grats verse host disease Xeno-graft host disease(XGVHD) model,probing its immunologic mechamism.Methods: Mouse splenic lymphocyte were collected in asepsis and treated by mitomycin as activating cell. Human Peripheral blood lymphocytes (hPBL)were separated and gathered as reacting cell; Mouse splenic lymphocyte and hPBL were mixed to incubate for a week. Destroying recipient (mouse) immune system by total body irradiation (TBI) and intraperitoneal injecting CTX、MTX; Separating and collecting hPBL; Injecting hPBL to mouse by caudal vein. Results; ①HPBL in the experiment groups(mixed mouse lymphocyte) proliferated obviously, the amount of 3H-TdR in corporation increased evidently(P<0.05); The mean percentage of CD 4、CD 8、IgG 、IgM positive cells rose markedly. ②Experiment groups,the hPBL were found in the spleen and kidney tissue, fas protein expressing, we occasionally discovered and apoptosis cells.Conclusion: The human to mouse one-way MLC has obvious lymphocyte proliferation. By these means,we succeed in inducing XGVHD and setting up a XGVHD model.

Study on conveyor natural frequency and time intervalfor switching off resistances

A conveyor belt driven by wound rotor motors produces dynamic tension, velocity and accelerationduring starting. The terrible situation (such as resonance) in dynamic analysis and design is that system naturalfrequencies are equal to those for switching off electric resistances. This paper analyzes and determines systemnatural frequencies based on a modeling method of receptances with the analysis of sub-systems model and of theprinciple of their addition and conveyor loop closure. It also puts forward to calculate the time interval for switching off electric resistances. The starting of one conveyor is simulated by lumped-mass-spring-model software tofurther illustrate the influence of time interval for switching off electric resistances on conveyor dynamic behavior. Two methods are also compared. The receptance model is proved to be an excellent alternative.

Research on steel-fibber polymer concrete machine tool structure

Researched on the design and manufacturing of machine tool bed made by Steel-fibber Polymer Concrete(SFPC),which analyzed the static,dynamic and thermal performances of the bed.The results of study prove that machine tool bed made with SFPC is much more superiority than made in cast iron in dynamic and thermal perform- ances,and is more superiority then made in Polymer Concrete (PC) in static perform- ances.It can be concluded that the static,dynamic and thermal properties of machine tool can be improved by manufacturing machine tool bed with SFPC.Also SFPC machine tool bed posses some other advantages in the following: short development time,simple pro- duction process,reducing cost cost,saving energy,iron and steel.

Phage displaying peptides mimic schistosoma antigenic epitopes selected by rat natural antibodies and protective immunity induced by their immunization in mice

AIM: To obtain the short peptides mimic antigenic epitopes selected by rat natural antibodies to schistosomes, and to explore their immunoprotection against schistosomiasis in mice.METHODS: Adults worm antigens (AWA) were analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and enzyme-linked transferred immunoblotting methods with normal SD rat sera (NRS). The killing effects on schistosomula with fresh and heat-inactivated sera from SD rats were observed. Then the purified IgG from sera of SD rats was used to biopan a phage random peptide library and 20 randomly selected positive clones were detected by ELISA and 2 of them were sequenced.Sixty female mice were immunized thrice with positive phage clones (0, 2nd, 4th wk). Each mouse was challenged with 40 cercariae, and all mice were killed 42 d after challenge. The worms and the liver eggs were counted. RESULTS: NRS could specifically react to the molecules of 75 000, 47 000, 34 500 and 23 000 of AWA. Sera from SD rats showed that the mortality rate of schistosomula was 76.2%, and when the sera were heat-inactivated in vitro, the mortality rate was decreased to 41.0% after being cultured for 48 h. The specific phages bound to IgG were enriched about 300-folds after three rounds of biopanning. Twenty clones were detected by ELISA, 19 of them bound to the specific IgG of rat sera. Immunization with these epitopes was carried out in mice. Compared with the control groups, the mixture of two mimic peptides could induce 34.9% (P = 0.000) worm reduction and 67.6% (P = 0.000) total liver egg reduction in mice. Two different mimic peptides could respectively induce 31.0% (P = 0.001), 14.5% (P = 0.074) worm reduction and 61.2% (P = 0.000), 35.7% (P = 0.000) total liver egg reduction. The specific antibody could be induced by immunization of the mimic peptides, and the antibody titer in immunized mice reached more than 1:6 400 as detected by ELISA.CONCLUSION: Specific peptides mimic antigenic molecules can be obtained by biopanning the phage random peptide library and a partially protective immunity against schistosome infection can be stimulated by these phage epitopes in mice.

Hydraulic cylinder control of injection molding machine based on differential evolution fractional order PID

Injection molding machine,hydraulic elevator,speed actuators belong to variable speed pump control cylinder system.Because variable speed pump control cylinder system is a nonlinear hydraulic system,it has some problems such as response lag and poor steady-state accuracy.To solve these problems,for the hydraulic cylinder of injection molding machine driven by the servo motor,a fractional order proportion-integration-diferentiation(FOPID)control strategy is proposed to realize the speed tracking control.Combined with the adaptive differential evolution algorithm,FOPID control strategy is used to determine the parameters of controller on line based on the test on the servo-motor-driven gear-pump-controlled hydraulic cylinder injection molding machine.Then the slef-adaptive differential evolution fractional order PID controller(SADE-FOPID)model of variable speed pump-controlled hydraulic cylinder is established in the test system with simulated loading.The simulation results show that compared with the classical PID control,the FOPID has better steady-state accuracy and fast response when the control parameters are optimized by the adaptive differential evolution algorithm.Experimental results show that SADE-FOPID control strategy is effective and feasible,and has good anti-load disturbance performance.

Electrical bioimpedance gastric motility measurement based on an electrical-mechanical composite mechanism

AIM： To introduce a bioimpedance gastric motility mea- surement method based on an electrical-mechanical composite concept and a preliminary clinical application. METHODS： A noninvasive gastric motility measure- ment method combining electrogastrograrn （EGG） and impedance gastric motility （IGM） test was used. Prelim- inary clinical application studies of patients with func- tional dyspepsia （FD） and gastritis, as well as healthy controls, were carried out. Twenty-eight FD patients （mean age 40.9±9.7 years） and 40 healthy volun- teers （mean age 30.9±7.9 years） were involved. IGM spectrum was measured for both the healthy subjects and FD patients, and outcomes were compared in the FD patients before treatment and 1 wk and 3 wk after treatment. IGM parameters were obtained from 30 erosive gastritis patients （mean age 50.5±13.0 years） and 40 healthy adults, and IGM and EGG results were compared in the gastritis patients before treatment and 1 wk after treatment.RESULTS： There were significant differences in the IGM parameters between the FD patients and healthy subjects, and FD patients had a poorer gastric motility [percentage of normal frequency （PNF） 70.8±25.5 in healthy subjects and 28.3 =t= 16.9 in FD patients, P 〈 0.01]. After 1 wk administration of domperidone 10 mg, tid, the gastric motility of FD patients was not im- proved, although the EGG of the patients had returned to normal. After 3 wk of treatment, the IGM rhythm of the FD patients became normal. There was a significant difference in IGM parameters between the two groups （PNF 70.4：1：25.5 for healthy subjects and 36.1 4- 21.8 for gastritis patients, P 〈 0.05）. The EGG rhythm of the gastritis patients returned to normal （frequency insta- bility coefficient 2.22±0.43 before treatment and 1.77 ：t： 0.19 one wk after treatment, P 〈 0.05） after 1 wk of treatment with sodium rabeprazole tablets, 10 mg, qd, po, qm, while some IGM parameters showed a tenden- cy toward improvement but had not reached statistical significance. CONCLUSION： The electrical-mechanical composite measurement method showed an attractive clinical appli- cation prospect in gastric motility research and evaluation.

Mechanisms of inducible resistance against Bacillus thuringiensis endotoxins in invertebrates

Resistance in insect pests against the endotoxin of Bacillus thuringiensis （Berliner） （Bt） is a major threat to the usefulness of this biopesticide, both used as traditional formulations and in transgenic crops. A crucial requirement for the development of successful resistance management strategies is a molecular understanding of the nature and inheritance of resistance mechanisms. This information can be used to design management strategies that will delay or counteract Bt resistance. The best known Bt resistance mechanism is inactivation of brush border membrane receptors. This type of resistance has a largely recessive mode of inheritance, which has enabled the design of resistance management approaches involving high dose and refuge strategies. Recent observations suggest that other resistance mechanisms are possible, including a mechanism that sequesters the toxin in the gut lumen through inducible immune reactions. The elevated immune status associated with tolerance to the toxin can be transmitted to subsequent generations by a maternal effect, which has implications for resistance management in the field. The high dose/refuge strategy may not be appropriate for the management of these alternative resistance mechanisms and other strategies have to be developed if inducible dominant resistance or tolerance mechanisms occur frequently in the field.

Virus genomes and virus-host interactions in aquaculture animals

Over the last 30 years,aquaculture has become the fastest growing form of agriculture production in the world,but its development has been hampered by a diverse range of pathogenic viruses.During the last decade,a large number of viruses from aquatic animals have been identified,and more than 100 viral genomes have been sequenced and genetically characterized.These advances are leading to better understanding about antiviral mechanisms and the types of interaction occurring between aquatic viruses and their hosts.Here,based on our research experience of more than 20 years,we review the wealth of genetic and genomic information from studies on a diverse range of aquatic viruses,including iridoviruses,herpesviruses,reoviruses,and rhabdoviruses,and outline some major advances in our understanding of virus–host interactions in animals used in aquaculture.

Accelerated antibacterial red-carbon dots with photodynamic therapy against multidrug-resistant Acinetobacter baumannii

The emergence of antibiotic resistance in bacteria is a major public-health issue.Synthesis of efficient antibiotic-free material is very important for fighting bacterial infection-related diseases.Herein,red-carbon dots(R-CDs)with a broad range of spectral absorption(350–700 nm)from organic bactericides or intermediates were synthesized through a solvothermal route.The prepared R-CDs not only had intrinsic antibacterial activities,but also could kill multidrug-resistant bacteria(multidrug-resistant Acinetobacter baumannii(MRAB)and multidrug-resistant Staphylococcus aureus(MRSA))effectively by generating reactive oxygen species.Furthermore,R-CDs could eliminate and inhibit the formation of MRAB biofilms,while conferring few side effects on normal cells.A unique property of R-CDs was demonstrated upon in vivo treatment of antibiotic-sensitive MRABinduced infected wounds.These data suggested that this novel R-CDs-based strategy might enable the design of nextgeneration agents to fight drug-resistant bacteria.