The current ulcerative colitis （UC） treatment algorithm involves a step-up therapeutic strategy, mainly aiming at inducing and maintaining its clinical remission. Although this therapeutic strategy may seem to be co...The current ulcerative colitis （UC） treatment algorithm involves a step-up therapeutic strategy, mainly aiming at inducing and maintaining its clinical remission. Although this therapeutic strategy may seem to be cost-efficient and reduce the risk of side effects, recent trials and case reports have shown that top-down therapy using infliximab induces a rapid clinical response, enhances patient quality of life, promotes mucosal healing, reduces surgeries and indirect cost of treatment for patients with severe UC. Moreover, since long-term treatment with infliximab is safe and well tolerated, early aggressive top-down therapeutic strategy may be a more effective approach, at least in a subgroup of severe extensive UC patients.展开更多
Energy saving is the crucial task of green architecture,energy-saving design and evaluation should be interactive.Low Energy Certificate(LEC),an interactive computer program for energy efficiency and certification of ...Energy saving is the crucial task of green architecture,energy-saving design and evaluation should be interactive.Low Energy Certificate(LEC),an interactive computer program for energy efficiency and certification of building envelope,is briefly introduced in this paper in aspects of certification standards,procedure,methods etc.Through the evaluation report of Innovation-pavilion PoI features,reference values of LEC are presented.展开更多
文摘The current ulcerative colitis （UC） treatment algorithm involves a step-up therapeutic strategy, mainly aiming at inducing and maintaining its clinical remission. Although this therapeutic strategy may seem to be cost-efficient and reduce the risk of side effects, recent trials and case reports have shown that top-down therapy using infliximab induces a rapid clinical response, enhances patient quality of life, promotes mucosal healing, reduces surgeries and indirect cost of treatment for patients with severe UC. Moreover, since long-term treatment with infliximab is safe and well tolerated, early aggressive top-down therapeutic strategy may be a more effective approach, at least in a subgroup of severe extensive UC patients.
文摘Energy saving is the crucial task of green architecture,energy-saving design and evaluation should be interactive.Low Energy Certificate(LEC),an interactive computer program for energy efficiency and certification of building envelope,is briefly introduced in this paper in aspects of certification standards,procedure,methods etc.Through the evaluation report of Innovation-pavilion PoI features,reference values of LEC are presented.
