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断指再植后发生静脉危象患者外科治疗方法研究 被引量:2
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作者 陈益 王胜伟 李文东 《中国现代医生》 2017年第10期84-87,共4页
目的探讨两种静脉皮瓣修复术对断指再植后发生静脉危象患者的不同治疗作用。方法采用随机数字表的方法将于2015年1月~2016年3月来我院就诊的断指再植后发生静脉危象患者共50例随机分为两组,分别为A组(游离静脉皮瓣组)和B组(带蒂邻指静... 目的探讨两种静脉皮瓣修复术对断指再植后发生静脉危象患者的不同治疗作用。方法采用随机数字表的方法将于2015年1月~2016年3月来我院就诊的断指再植后发生静脉危象患者共50例随机分为两组,分别为A组(游离静脉皮瓣组)和B组(带蒂邻指静脉皮瓣组),每组各25例。两组患者采取不同手术治疗,术中记录各组手术时间;术后随访6个月,利用密歇根手调查问卷(MHQS)评定表对临床疗效进行判定,并且观察记录再植成活率。结果 A组手术时间明显长于B组,且差异显著;A组断指成活率为88.00%,B组成活率为96.00%,B组显著高于A组且差异具有统计学意义。B组临床治疗效果优良率略高于A组,但两组数据无显著性差异。结论采用带蒂邻指静脉皮瓣法治疗断指再植后发生静脉危象患者较好,这种修复方式采用了健康的相邻手指的皮肤作为供体,覆盖了损伤部位,因此对于术者的手术操作要求较低,让手术更加方便简单,且这种修复方式也能较好的防止再次发生静脉危象现象,提高断指的成活率。 展开更多
关键词 静脉皮瓣修复 指再生 静脉危象 临床观察
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人体应用的器官再生技术公告 被引量:3
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作者 徐荣祥 《中国烧伤创疡杂志》 2013年第4期241-248,共8页
希波克拉底在2500年前创立的现代医学,为人类的健康做出了巨大的贡献。治愈人体器官疾病是历代生命科学家、医学家一直向往攻克的难题。半个多世纪以来,纳税人将数千亿美元的研究经费用于探索人体器官疾病的治愈,但并没有得到回报。特... 希波克拉底在2500年前创立的现代医学,为人类的健康做出了巨大的贡献。治愈人体器官疾病是历代生命科学家、医学家一直向往攻克的难题。半个多世纪以来,纳税人将数千亿美元的研究经费用于探索人体器官疾病的治愈,但并没有得到回报。特别是人类基因之父沃森教授于2013年3月21日宣布基因应用研究没有价值后,人体器官疾病的攻克更是遥遥无期。2013年7月12日,我国生命科学家徐荣祥教授发布已实现奥巴马总统的"发展药物使损伤器官再生"生命科学决策目标的声明:在美国公布治愈器官疾病的专有器官再生科学技术,望政府尽快验证并使用,以造福人类。 展开更多
关键词 人体器官原位再生技术 再生营养物质 科学公告 指再生 再生还童
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Relationship between Living Rate of Bud and Emergence Rate of Ratoon Rice and Characteristics of the First Cropping Mid-season Hybrid Rice
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作者 张林 熊洪 +4 位作者 徐富贤 朱永川 郭晓艺 周兴兵 刘茂 《Agricultural Science & Technology》 CAS 2012年第9期1873-1876,1895,共5页
[Objective] The aim was to study the relationship of plant characters with bud living rate and mother stem emergence rate of ratoon rice before harvest. [Method] Eighteen mid-season hybrid rice cultivators approved re... [Objective] The aim was to study the relationship of plant characters with bud living rate and mother stem emergence rate of ratoon rice before harvest. [Method] Eighteen mid-season hybrid rice cultivators approved recently were taken as materials and relationship of plant characters including bud living rate and moth- er stem emergence rate of ratoon rice before harvest was explored, based on relat- ed data. [Result] The shorter rice with lower harvesting index is the main character of high emergence rate for first cropping rice; decline of plant height and increase of ear-bearing percentage would improve emergence of regenerative seedlings. [Conclusion] The research provided scientific reference for breeding of rice cultivars with high regenerative capacity. 展开更多
关键词 Mid-season hybrid rice Plant characters Bud living rate Emergencerate
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Expression of phosphatase regenerating liver 3 is an independent prognostic indicator for gastric cancer 被引量:8
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作者 Ni Dai Ai-Ping Lu +1 位作者 Cheng-Chao Shou Ji-You Li 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第12期1499-1505,共7页
AIM: To investigate the prognostic significance of phosphatase regenerating liver 3 (PRL-3) protein expression in gastric cancer.METHODS: PRL-3 expression in paraffin-embedded tumor specimens from 293 patients wit... AIM: To investigate the prognostic significance of phosphatase regenerating liver 3 (PRL-3) protein expression in gastric cancer.METHODS: PRL-3 expression in paraffin-embedded tumor specimens from 293 patients with gastric cancer was studied retrospectively by immunohistochemistry. Nonoclonal antibody specifically against PRL-3, 3B6, was obtained with hybridoma technique.RESULTS: Positive PRL-3 expression was detected in 43.3% (227 of 293) of gastric cancer cases. High expression of PRL-3 was positively correlated with tumor size, depth of invasion, vascular/lymphatic invasion, lymph node metastasis, high TNM stage and tumor recurrence. Patients with positive PRL-3 expression had a significantly lower 5-year survival rate than those with negative expression (28.3% vs 52.9%, P 〈 0.0001). Patients who received curative surgery, and with positive PRL-3 expression had a significant shorter overall survival and disease-free disadvantage over patients with negative expression (hazard ratio of 16.7 and 16.6, respectively; P 〈 0.0001 for both). Multivariate analysis revealed that PRL-3 expression was an independent prognostic indicator for overall and disease-free survival of gastric cancer patients, particularly for survival in TNM stage Ⅲ patients. CONCLUSION: PRL-3 expression is a new independent prognostic indicator to predict the potential of recurrence and survival in patients with gastric cancer at the time of tumor resection, 展开更多
关键词 Phosphatase regenerating liver 3 Gastriccancer PROGNOSIS RECURRENCE ANTIBODY
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Study on the Flowering Regulator of the Paeonia suffruticosa "Hongdan Lan"
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作者 Min Deng Suping Gao Yang Guo 《Journal of Agricultural Science and Technology(B)》 2012年第7期824-834,共11页
In the study, Southwest peony varieties group of Paeonia suffruticosa "Hongdan Lan" were analyzed, test was mainly divided into two parts, one is the nature of the low temperature, through the external environment i... In the study, Southwest peony varieties group of Paeonia suffruticosa "Hongdan Lan" were analyzed, test was mainly divided into two parts, one is the nature of the low temperature, through the external environment is mainly (temperature, light) gibberellin and nutrition solution regulation, on the Tianpeng peony florescence control technological research. The second is to explore the flower forcing peony after anthesis regeneration technique. The main research results: comprehensive gibberellin peony flower induction of morphological and physiological indexes, such as gibberellin concentration of 150 mgFL and 200 mg/L the effect of flower induction was better than the other treatments; gibberelin (GA3) breaking the dormancy of the peony to blossom ahead of time has the promoter action, also has certain effect on nutritional growth; to premature flowering the abscisic acid (ABA) has opposite effect; whereas auxin (IAA) and corn (ZT) effect was not obvious; rejuvenation results showed that after a year of conservation and managemental measures, flower induction after the flower of peony played a very important role in the restoration. After the winter flower induction, peony flowerpot of soil hardening, through the soil replacement, repair of roots, flower peony recovery showed a very significant effect. 展开更多
关键词 TianPeng peony flowering regulation Gibberellin (GA3) nutrition solution accumulated temperature rejuvenation.
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吻合血管的游离拇甲瓣移植再造拇或示指15例报告
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作者 张功林 葛宝丰 +3 位作者 丘耀元 刘扣有 王立安 姜世平 《中华整形烧伤外科杂志》 CAS CSCD 北大核心 1989年第2期95-97,156-157,共3页
1986年元月至1987年6月,共应用吻合血管的拇甲瓣移植再造拇指13例,示指2例,都取得成功。作者认为,肋骨移植优于髂骨移植。讨论了移植技术的改进,并报告了2例典型病例。
关键词 拇甲瓣 指再生 吻合血管
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Evolution of Proinflammatory Cytokines in Hepatocellular Carcinoma Patients Undergoing Orthotopic Liver Transplantation
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作者 Yu-liang WANG Yu ZHANG +1 位作者 Zhi-jun ZHU Rui-fa HAN 《Clinical oncology and cancer researeh》 CAS CSCD 2011年第1期38-41,共4页
OBJECTIVE To analyze the expression and levels of serum proinflammatory cytokines including tumor necrosis factor alpha (TNF-α), and interleukin (IL)-6 in patients with hepatocellular carcinoma (HCC), who recei... OBJECTIVE To analyze the expression and levels of serum proinflammatory cytokines including tumor necrosis factor alpha (TNF-α), and interleukin (IL)-6 in patients with hepatocellular carcinoma (HCC), who received orthotopic liver transplantation (OLT).METHODS The blood samples of 20 consecutive HCC patients who underwent liver transplantation were detected and analyzed for the clinical serum biochemical parameters, TNF-α and IL-6.Blood samples were drawn from the radial artery at planned time points: preoperatively, intraoperatively, and postoperatively.Levels of serum TNF-α and IL-6 were detected with enzymelinked immunosorbent assay (ELISA).RESULTS The levels of serum TNF-αand IL-6 increased significantly at reperfusion phase compared with those detected preoperatively (P 〈 0.01), and the level of serum IL-6 remained significantly higher until the third day after the liver transplantation. There was a significant correlation between TNF-αand IL-6 (P〈0.001).CONCLUSION This research into the effects of the proinflammatory cytokines on liver transplantation has provided new insights into the mechanisms of ischemia and reperfusion injury to OLT. 展开更多
关键词 liver transplantation CARCINOMA HEPATOCELLULAR REPERFUSION CYTOKINES
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甲钴胺对指神经吻合后手指感觉功能恢复的疗效观察
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作者 邓勇 《按摩与康复医学》 2010年第3期19-20,共2页
目的:探讨甲钴胺(甲基维生素B12)对神经损伤的神经再生作用并对比不同剂量甲基维生素B12(甲钴胺)的神经再生作用。方法:将58例81指神经损伤术后的病例,根据病历号随机分为3组:A组:甲基维生素B12(甲钴胺)I500微克肌注每日一... 目的:探讨甲钴胺(甲基维生素B12)对神经损伤的神经再生作用并对比不同剂量甲基维生素B12(甲钴胺)的神经再生作用。方法:将58例81指神经损伤术后的病例,根据病历号随机分为3组:A组:甲基维生素B12(甲钴胺)I500微克肌注每日一次共一月后改500微克口服每日三次共四月;B组:维生素B12500微克肌注每日一次共一月后改500微克每日三次口服共四月;C组:阴性对照组。术后随访4~6月,平均随访5.6个月,定期测定手指指腹的30g压觉,2g触觉,5g痛觉以及两点辨别觉。结果:三组对照,实验组手指感觉恢复均明显优于阴性对照组,1500微克甲钴胺组感觉恢复优于500微克维生素组。结论:甲钴胺对指神经损伤的恢复有促进作用,且与药物的剂量呈正相关。 展开更多
关键词 神经再生 甲基维生素B12 甲钴胺
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Vascular endothelial growth factor promotes peripheral nerve regeneration after sciatic nerve transection in rat 被引量:1
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作者 Rahim Mohammadi Sima Ahsan +1 位作者 Masoume Masoumi Keyvan Amini 《Chinese Journal of Traumatology》 CAS CSCD 2013年第6期323-329,共7页
Objective:To evaluate the local effect of vascular endothelial growth factor (VEGF) on transected sciatic nerve regeneration.Methods:Sixty male white Wistar rats were divided into four experimental groups randomly... Objective:To evaluate the local effect of vascular endothelial growth factor (VEGF) on transected sciatic nerve regeneration.Methods:Sixty male white Wistar rats were divided into four experimental groups randomly (n=15).In transected group the left sciatic nerve was transected and the stump was fixed to adjacent muscle.In treatment group the defect was bridged using a silicone graft filled with 10μL VEGF.In silicone group the graft was filled with phosphate-buffered saline.In sham-operated group the sciatic nerve was exposed and manipulated.Each group was subdivided into three subgroups with five animals in each and nerve fibers were studied 4,8 and 12 weeks after operation.Results:Behavioral test,functional study of sciatic nerve,gastrocnemius muscle mass and morphometric indices confirmed a faster recovery of regenerated axons in VEGF group than in silicone group (P〈0.05).In immunohistochemical assessment,reactions to S-100 in VEGF group were more positive than that in silicone group.Conclusion:Local administration of VEGF will improve functional recovery and morphometric indices of sciatic nerve. 展开更多
关键词 Peripheral nerves Nerve regeneration Sciatic nerve Vascular endothelial growth factor
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