浙图藏《九宫谱》版本与查继佐曲学思想考

《九宫谱定》十二卷《总论》一卷,清东山钓史、鸳湖逸者同辑,浙江省图书馆孤山馆区藏有完整版本,但破损较为严重,原书版本信息页和序文页均缺损不见,内文字迹亦多有模糊。经与郑振铎藏本、苏州图书馆藏金阊绿荫堂刻本对比分析,可以确定三者为同一刻本。《九宫谱定》最终完成于查继佐入粤期间的顺治十四年(1657)至顺治十六年(1659),最终刊行应在顺治十七年(1660)的四月到秋末。该曲谱上承沈璟《增定查补南九宫十三调谱》、王骥德《曲律》,在理论与舞台实践方面进行了有益的探索和尝试,有一定的创见,其曲学思想影响了《钦定曲谱》,张大复的《寒山堂曲谱》《九宫大成南北词宫谱》,吴梅的《南北词简谱》《曲学通论》,许之衡的《曲律易知》,王季烈的《螾庐曲谈》等曲谱的编排和对南曲格律方面的订正,因此,在南曲谱研究上应引起重视。

Correlation analysis between the HPLC fingerprints and in vitro antibacterial activity of ethyl acetate extracts from Radix isatidis

Aim To study the correlation between the HPLC fingerprints and in vitro antibacterial activities of EtOAc extracts of Radix isatidis from various sources. Methods Ten batches of Radix isatidis EtOAc extracts were analyzed with HPLC and the fingerprints were established. The influence of EtOAc extracts on the thermogenic curve of growth of Escherchia coli was obtained by microcalorimetry. The chemical differences of EtOAc extracts of Radix isatidis from various sources in the HPLC fingerprints were probed with hierarchical clustering analysis and similarity analysis. The correlation between the HPLC fingerprints and in vitro antibacterial activities was analyzed with multivafiant correlation analysis. Results Close correlation existed between the HPLC fingerprints and in vitro antibacterial activities of EtOAc extracts of Radix isatidis. Conlusion The combination of HPLC fingerprints and antibacterial activities can be used to discover principle components of Radix isatidis on bioactivity.