Aiming at the problem of on-line damage diagnosis in structural health monitoring （SHM）, an algorithm of feature extraction and damage alarming based on auto-regressive moving-average （ARMA） time series analysis i...Aiming at the problem of on-line damage diagnosis in structural health monitoring （SHM）, an algorithm of feature extraction and damage alarming based on auto-regressive moving-average （ARMA） time series analysis is presented. The monitoring data were first modeled as ARMA models, while a principalcomponent matrix derived from the AR coefficients of these models was utilized to establish the Mahalanobisdistance criterion functions. Then, a new damage-sensitive feature index DDSF is proposed. A hypothesis test involving the t-test method is further applied to obtain a decision of damage alarming as the mean value of DDSF had significantly changed after damage. The numerical results of a three-span-girder model shows that the defined index is sensitive to subtle structural damage, and the proposed algorithm can be applied to the on-line damage alarming in SHM.展开更多
A new approach to damage classification for health monitoring of a time-varylng system is presented. The functional-series time-dependent auto regressive moving average （FS-TARMA） time series model is applied to the...A new approach to damage classification for health monitoring of a time-varylng system is presented. The functional-series time-dependent auto regressive moving average （FS-TARMA） time series model is applied to the vibration signal observed in the time-varying system for estimating the TAR/TMA parameters and the innovation variance. These parameters are the functions of the time, represented by a group of projection coefficients on the certain functional subspace with specific basis functions. The estimated TAR/TMA parameters and the innovation variance are further used to calculate the latent components （LCs） as the more informative data for health monitoring evaluation, based on an eigenvalue decomposition technique. LCs are then combined and reduced to numerical values （NVs） as feature sets, which are input to a probabilistic neural network （PNN） for the damage classification. For the evaluation of the proposed method, numerical simulations of the damage classification for a tlme-varylng system are used, in which different classes of damage are modeled by the mass or stiffness reductions. It is demonstrated that the method can identify the damages in the course of operation and the change of parameters on the time-varying background of the system.展开更多
[Objective] To introduce an improved method for DNA extraction from the faeces of red deer. [Method] Based on the traditional method of CTAB lysis, we proposed an improved DNA extraction method according to the charac...[Objective] To introduce an improved method for DNA extraction from the faeces of red deer. [Method] Based on the traditional method of CTAB lysis, we proposed an improved DNA extraction method according to the characteristics of red deer faeces. [Result] This improved method extracted high-quality fecal DNA from Tianshan red deer and amplified the mitochondrial cytochrome b gene. With the muscle and fur DNA of red deer as the control, the sequencing results further con- firmed the reliability of the method. [Conclusion] The method requires no proteinase K in the process of extraction, and the extracted DNA can be used for PCR ampli- fication directly without the purification of DNA purification kit, thus, it is cost-saving.展开更多
This paper introduces a new concept of ＂State Representation Methodology （SRM）＂ which is a kind of bridge condition assessment method for structural health monitoring system （SHM）. There are many methods for sys...This paper introduces a new concept of ＂State Representation Methodology （SRM）＂ which is a kind of bridge condition assessment method for structural health monitoring system （SHM）. There are many methods for system identification from the simplicity comparison of damage index to the complicated statistical pattern recognition algorithms in SHM. In these methods, modal analysis and parameters identification or many defined indices are common-used for extracting the dynamic or static characteristics of a system. However, there is a common problem： due to the complexity of a large size system with high-order nonlinear characteristics and severe environment interference, it is impossible to extract and quantify exactly these modal parameters or system parameters or indices as the feature vectors of a system in damage detection in an easy way. The SRM considered a more general theory for the non-parametric description of system state.展开更多
SC （Saussurea costus） （Asteraceae） is a traditionally known and potent plant which is well considered for its medicinal uses in different indigenous Indian systems of medicine. This study was undertaken to investi...SC （Saussurea costus） （Asteraceae） is a traditionally known and potent plant which is well considered for its medicinal uses in different indigenous Indian systems of medicine. This study was undertaken to investigate the hepatoprotective effect of SC against liver injury induced by CC14 intoxication. Animals were divided into five groups. Group I, served as normal control. Group II received 2 mL CC14/kg b.w. diluted with olive oil, at 1：1 ratio on day 11. Groups III and IV were pre-treated orally respectively with 100 and 200 mg/kg b.w. aqueous roots extract of SC for 10 days followed by subcutaneous injection of CC14 （2 mL/kg b.w.）, once on day 11. Group V were orally given Liv-52 （100 mg/kg b.w.） once daily for 10 days followed by subcutaneous injection of CC14 （2 mL/kg b.w.）, once on day 11. Our results show that, the activity of serum hepatic enzymes （ALT, AST, and ALP） were significantly elevated in guinea pigs treated with CC14, while both the SC root extract and Liv-52 reduced significantly these enzymes activity. Also, the levels of glucose, urea and cholesterol were decreased when compared with intoxicated control. Histopathological examination of intoxicated animals showed dilation, hemorrhage, vacuolization, inflammation and necrosis indicating liver damage, while the animals received SC or Liv-52 that showed less pathological effects or normal liver when compared to animals treated with CC14 alone. Biochemical and histological results confirm the hepatoprotective effect of aqueous extract of SC.展开更多
Ethanol extract of mixed algae--spirogyra and ulothrix was investigated to assess the effect on some biochemical parameters in UVB irradiated mice. The dorsal-thoracic region of mice were shaved and exposed to UVB rad...Ethanol extract of mixed algae--spirogyra and ulothrix was investigated to assess the effect on some biochemical parameters in UVB irradiated mice. The dorsal-thoracic region of mice were shaved and exposed to UVB radiation for 24 h for two consecutive weeks. Five groups of ten mice each were conducted： non-irradiated control and irradiated control. Mice treated with commercial cream （S.M.） at a dose of 0.1 mg/cm2 and mice treated with ethanol extract of mixed spirogyra and ulothrix at a dose of 0.1 mg/cm2 or 0.2 mg/cm2. Topical application was performed to all treated mice groups once a day for four consecutive weeks. Results showed significant differences between treated and control groups during the whole period of experiment. The clear potentiality of the ethanol extract was detected through body and skin weight, level of total protein, Superoxide Dismutase （SOD） and Catalase （CAT） activities in skin. However, UVB irradiated mice treated with 0.2 mg/cm2 exhibited the most significant effect when compared to control groups. That may be attributed to anti-inflammatory and anti-oxidant effects of algal extract.展开更多
Solanum incanum, a shrubby herb, is widely distributed and used as analgesic, antitoxic, and antispasmodic in folk medicine. In the present study, the protective effects of aqueous extract of S. incanum against acetam...Solanum incanum, a shrubby herb, is widely distributed and used as analgesic, antitoxic, and antispasmodic in folk medicine. In the present study, the protective effects of aqueous extract of S. incanum against acetaminophen induced acute liver damage were evaluated in guinea pigs. Animals were orally administered with S. incanum extract （50 and 100 mg/ kg bw） and silymarin （ 100 mg / kg bw） respectively for 6 days followed by acetaminophen administration （2 g / kg bw） at the 7th day. The results showed that the treatment with S. incanum extract significantly lowered the acetaminophen-induced serum levels of hepatic marker enzymes （AST, ALT, and ALP）, Liver histopathology also showed that S. incanum extract reduced the incidence of liver lesions including the swelling of hepatic cells, lymphocytes infiltration, nucleus condensation, and hepatic necrosis induced by acetaminophen treatment in guinea pigs. The S. incanum extract at a dose of 100 mg / kg bw was more effective in suppressing the oxidative damage than the extract at a dose of 50 mg / kg bw. Therefore, the results of this study suggest that S. incanum extract could protect liver against the acetaminophen-induced oxidative damage.展开更多
基金The National High Technology Research and Devel-opment Program of China (863Program) (No2006AA04Z416)the National Natural Science Foundation of China (No50538020)
文摘Aiming at the problem of on-line damage diagnosis in structural health monitoring （SHM）, an algorithm of feature extraction and damage alarming based on auto-regressive moving-average （ARMA） time series analysis is presented. The monitoring data were first modeled as ARMA models, while a principalcomponent matrix derived from the AR coefficients of these models was utilized to establish the Mahalanobisdistance criterion functions. Then, a new damage-sensitive feature index DDSF is proposed. A hypothesis test involving the t-test method is further applied to obtain a decision of damage alarming as the mean value of DDSF had significantly changed after damage. The numerical results of a three-span-girder model shows that the defined index is sensitive to subtle structural damage, and the proposed algorithm can be applied to the on-line damage alarming in SHM.
文摘A new approach to damage classification for health monitoring of a time-varylng system is presented. The functional-series time-dependent auto regressive moving average （FS-TARMA） time series model is applied to the vibration signal observed in the time-varying system for estimating the TAR/TMA parameters and the innovation variance. These parameters are the functions of the time, represented by a group of projection coefficients on the certain functional subspace with specific basis functions. The estimated TAR/TMA parameters and the innovation variance are further used to calculate the latent components （LCs） as the more informative data for health monitoring evaluation, based on an eigenvalue decomposition technique. LCs are then combined and reduced to numerical values （NVs） as feature sets, which are input to a probabilistic neural network （PNN） for the damage classification. For the evaluation of the proposed method, numerical simulations of the damage classification for a tlme-varylng system are used, in which different classes of damage are modeled by the mass or stiffness reductions. It is demonstrated that the method can identify the damages in the course of operation and the change of parameters on the time-varying background of the system.
基金Supported by the National Natural Science Foundation of China(31060152)the Natural Science Foundation of the Xinjiang Uygur Autonomous Region,China(2010211A02)the Key Program for Animal Sciences of Xinjiang University,China~~
文摘[Objective] To introduce an improved method for DNA extraction from the faeces of red deer. [Method] Based on the traditional method of CTAB lysis, we proposed an improved DNA extraction method according to the characteristics of red deer faeces. [Result] This improved method extracted high-quality fecal DNA from Tianshan red deer and amplified the mitochondrial cytochrome b gene. With the muscle and fur DNA of red deer as the control, the sequencing results further con- firmed the reliability of the method. [Conclusion] The method requires no proteinase K in the process of extraction, and the extracted DNA can be used for PCR ampli- fication directly without the purification of DNA purification kit, thus, it is cost-saving.
文摘This paper introduces a new concept of ＂State Representation Methodology （SRM）＂ which is a kind of bridge condition assessment method for structural health monitoring system （SHM）. There are many methods for system identification from the simplicity comparison of damage index to the complicated statistical pattern recognition algorithms in SHM. In these methods, modal analysis and parameters identification or many defined indices are common-used for extracting the dynamic or static characteristics of a system. However, there is a common problem： due to the complexity of a large size system with high-order nonlinear characteristics and severe environment interference, it is impossible to extract and quantify exactly these modal parameters or system parameters or indices as the feature vectors of a system in damage detection in an easy way. The SRM considered a more general theory for the non-parametric description of system state.
文摘SC （Saussurea costus） （Asteraceae） is a traditionally known and potent plant which is well considered for its medicinal uses in different indigenous Indian systems of medicine. This study was undertaken to investigate the hepatoprotective effect of SC against liver injury induced by CC14 intoxication. Animals were divided into five groups. Group I, served as normal control. Group II received 2 mL CC14/kg b.w. diluted with olive oil, at 1：1 ratio on day 11. Groups III and IV were pre-treated orally respectively with 100 and 200 mg/kg b.w. aqueous roots extract of SC for 10 days followed by subcutaneous injection of CC14 （2 mL/kg b.w.）, once on day 11. Group V were orally given Liv-52 （100 mg/kg b.w.） once daily for 10 days followed by subcutaneous injection of CC14 （2 mL/kg b.w.）, once on day 11. Our results show that, the activity of serum hepatic enzymes （ALT, AST, and ALP） were significantly elevated in guinea pigs treated with CC14, while both the SC root extract and Liv-52 reduced significantly these enzymes activity. Also, the levels of glucose, urea and cholesterol were decreased when compared with intoxicated control. Histopathological examination of intoxicated animals showed dilation, hemorrhage, vacuolization, inflammation and necrosis indicating liver damage, while the animals received SC or Liv-52 that showed less pathological effects or normal liver when compared to animals treated with CC14 alone. Biochemical and histological results confirm the hepatoprotective effect of aqueous extract of SC.
文摘Ethanol extract of mixed algae--spirogyra and ulothrix was investigated to assess the effect on some biochemical parameters in UVB irradiated mice. The dorsal-thoracic region of mice were shaved and exposed to UVB radiation for 24 h for two consecutive weeks. Five groups of ten mice each were conducted： non-irradiated control and irradiated control. Mice treated with commercial cream （S.M.） at a dose of 0.1 mg/cm2 and mice treated with ethanol extract of mixed spirogyra and ulothrix at a dose of 0.1 mg/cm2 or 0.2 mg/cm2. Topical application was performed to all treated mice groups once a day for four consecutive weeks. Results showed significant differences between treated and control groups during the whole period of experiment. The clear potentiality of the ethanol extract was detected through body and skin weight, level of total protein, Superoxide Dismutase （SOD） and Catalase （CAT） activities in skin. However, UVB irradiated mice treated with 0.2 mg/cm2 exhibited the most significant effect when compared to control groups. That may be attributed to anti-inflammatory and anti-oxidant effects of algal extract.
文摘Solanum incanum, a shrubby herb, is widely distributed and used as analgesic, antitoxic, and antispasmodic in folk medicine. In the present study, the protective effects of aqueous extract of S. incanum against acetaminophen induced acute liver damage were evaluated in guinea pigs. Animals were orally administered with S. incanum extract （50 and 100 mg/ kg bw） and silymarin （ 100 mg / kg bw） respectively for 6 days followed by acetaminophen administration （2 g / kg bw） at the 7th day. The results showed that the treatment with S. incanum extract significantly lowered the acetaminophen-induced serum levels of hepatic marker enzymes （AST, ALT, and ALP）, Liver histopathology also showed that S. incanum extract reduced the incidence of liver lesions including the swelling of hepatic cells, lymphocytes infiltration, nucleus condensation, and hepatic necrosis induced by acetaminophen treatment in guinea pigs. The S. incanum extract at a dose of 100 mg / kg bw was more effective in suppressing the oxidative damage than the extract at a dose of 50 mg / kg bw. Therefore, the results of this study suggest that S. incanum extract could protect liver against the acetaminophen-induced oxidative damage.
