议论文写作要有说服性

议论文是摆事实、讲道理的文章。议论文的基本特点是它的说服性。一、论点要正确。所谓论点,是作者在文章中对所论述的问题提出的见解、主张和表示的态度。它是整个论证的中心,确立论点的要求,一个是正确,一个是在正确基础上的深刻。二。

“人猿同祖论”

人类是从那里来的?许多世纪都一直是个哑谜。基督教的《圣经》说,人是上帝造的,而且编造了一大堆动听的神话。十九世纪五十年代,托马斯·赫胥黎根据进化论原理,以充分的科学论据证实人猿同祖,从而揭示了人类起源之谜,推翻了上帝造人的谎言。

Overview of immunosuppression in liver transplantation

Continued advances in surgical techniques and immunosuppressive therapy have allowed liver transplantation to become an extremely successful treatment option for patients with end-stage liver disease.Beginning with the revolutionary discovery of cyclosporine in the 1970s,immunosuppressive regimens have evolved greatly and current statistics confirm one-year graft survival rates in excess of 80%. Immunosuppressive regimens include calcineurin inhibitors,anti-metabolites,mTOR inhibitors,steroids and antibody-based therapies.These agents target different sites in the T cell activation cascade,usually by inhibiting T cell activation or via T cell depletion.They are used as induction therapy in the immediate periand post-operative period,as long-term maintenance medications to preserve graft function and as salvage therapy for acute rejection in liver transplant recipients. This review will focus on existing immunosuppressive agents for liver transplantation and consider newer medications on the horizon.

Radiotherapy in Non-Functioning Pituitary Macroadenoma： Mansoura Experience

OBJECTIVE The current retrospective study aims to evaluate the management of non-functioning the assessment of experience on pituitary macroadenoma through clinical, biochemical, radiological features, and treatment outcome of patients, and to identify prognostic factors affecting progression-free survival （PFS）. METHODS Data of 55 patients macroadenoma presented to the with non-functioning pituitary Clinical Oncology and Nuclear Medicine department between 1998 and 2009 were investigated. RESULTS The most common symptom was visual disturbance （38.2%） followed by headache （27.3%）. The presence of male predominance was observed （1.4：1）. Ten patients received radio-therapy （RT） only. Extrasellar extension was the more common treatment. The overall response rate was 72.8% with completed response at 16.4%. Memory and intellectual sequelae were the most common late complications of treatment （14%）. The ten-year PFS was at 84.6%. PFS was found to be significantly better with higher dose of RT （up to 54 Gy）, treatment by both surgery and RT, absence of visual field defect, and tumor localized to sella, whereas it was not significantly affected by age and sex. CONCLUSION The data confirmed that the prevalence of mass effect and hypopituitarism in patients with non-functioning pituitary macroadenoma is elevated. Conventional external RT up to 54 Gy is safe and effective in controlling non-functioning pituitary macro- adenoma with tolerable and acceptable morbidity.

Large-eddy Simulation of Ethanol Spray-Air Combustion and Its Experimental Validation

Large-eddy simulation of spray combustion is under its rapid development.Different combustion models were used by different investigators.However,these models are less validated by detailed experimental data.In this paper,large-eddy simulation(LES)of ethanol spray-air combustion was made using an Eulerian-Lagrangian approach,a subgrid-scale kinetic energy stress model,and a filtered finite-rate combustion model,neglecting the sub-grid scale reaction rate.The simulation results are compared with experimental dada in the literature and validated in detail.The LES obtained statistically averaged gas temperature is in much better agreement with the experimental results than Reynolds averaged(RANS)modeling using the most complex probability density function(PDF)equation combustion model.The instantaneous LES results show the coherent structures of the shear region near the high-temperature flame zone and the fuel vapor concentration map,indicating that the droplets are concentrated in this shear region.The instantaneous temperature,oxygen and carbon dioxide concentration maps show the close interaction between the coherent structures and the combustion reaction.

Relationship between cultivated land use functions and land rental behavior of rural households:empirical evidence from different dominant functional regions in central China

This paper analyzes the relationship between the cultivated land use functions and the land rental decisions of rural households in three Dominant Functional Zones of Hubei, China. The results indicate that 41.10% of the rural households in the study areas participated in the land rental market. The land rental market in the Key Development Zone has both a higher participation rate and land rent; the Agricultural Production Zone has a higher participation rate but a lower land rent; and the land rental market in the Key Ecological Zone is underdeveloped. The difference in regional function and economic level leads to a significant difference in the spatial variation of the cultivated land use multifunction. Overall, the cultivated land function of rural households has a significant impact on their land transfer behavior. The higher the Functions of Economic Contribution, Food Production, and Pension & Employment, the more willing the rural households are to rent in the land, while the higher the Function of Inheritance and Retainment of the cultivated land use, the more likely the peasants are to retain their cultivated land resources. Furthermore, the correlation coefficient is significantly higher in the Key Development Zone than in the Key Ecological Zone.

Upper bound solutions for supporting pressures of shallow tunnels with nonlinear failure criterion

Linear failure criterion is widely used in calculation of earth pressure acting on shallow tunnels. However, experimental evidence shows that nonlinear failure criterion is able to represent fairly well the failure of almost all types of rocks, A nonlinear Hock-Brown failure criterion is employed to estimate the supporting pressures of shallow tunnels in limit analysis framework. Two failure mechanisms are proposed for calculating the work rate of extemal force and the internal energy dissipation. A tangential line to the nonlinear failure criterion is used to formulate the supporting pressure problem as a nonlinear programming problem. The objective function formulated in this way is minimized with respect to the failure mechanism and the location of tangency point. In order to assess the validity, the supporting pressures for the proposed failure mechanisms are calculated and compared with each other, and the present results are compared with previously published solutions when the nonlinear criterion is reduced to linear criterion. The agreement supports the validity of the proposed failure mechanisms. An experiment is conducted to investigate the influences of the nonlinear criterion on collapse shape and supporting pressures of shallow tunnels.

Determinants of workers'attitude toward low-carbon technology adoption:empirical evidence from Chinese firms

As the main contribution of China's carbon emissions, low-carbon production in industrial firms becomes an inevitable choice, and industrial firm employees' attitudes on low-carbon new technology directly influence the results of low-carbon production. Based on the Unified Theory of Acceptance and Use of Technology model, structural equation modeling was used to analyze the main factors influencing firm staff to accept low-carbon new technology. The study reveals that the employee's social impact, performance expectation, effort expectations and convenient conditions, and employee characteristics are all main factors affecting their acceptance attitudes on low-carbon new technology. And social influence has the largest effect on employees' acceptance attitudes toward low-carbon new technology. Accordingly, relevant policy recommendations are put forward for the future research direction.

Quantitative study on the urban fresh water consumption since Chinese rapid urbanization

The development of urbanization has a close relationship with fresh water resources, especially in the rapid urbanization period. By analyzing the course of the urhanization development and the experience of international urbanization development, the paper confirms the starting time of the rapid urbanization. Based on the ecotogical theory; urban fresh water consumption is composed of three types： the direct, the indirect and the induced water consumption. And the paper constructs calculation model of the indirect and the induced water consumption. Using the related statistics data, the paper makes an empirical research on the changes of the amount and structure of water consumption. Then it discusses the correlation between the water consumption and the amount of urban population, and the result shows that the amount of the water consumption arid the urban population have a remarkable correlation with the exception of the amount of the indirect water consumption, and the curves fake on quadratic functian form. Last, from the urban fimction point of view; the paper anatomizes the cause of the urban water consumption changes.

RNF13： a novel RING-type ubiquitin ligase over-expressed in pancreatic cancer

Protein ubiquitination by E3 ubiquitin ligases plays an important role in cancer development. In this study, we provide experimental evidence that a RING-finger-containing protein RNF13 is an ER/Golgi membrane-associated E3 ubiquitin ligase and its RING finger domain is required for the ubiquitin ligase activity. Immunohistochemical analysis of pancreatic ductal adenocarcinoma （PDAC） and paracancerous normal tissues from 72 patients documented RNF13 over-expression in 30 tumor samples （41.7%, 30/72）, and its expression was significantly associated with histological grading （P= 0.024）. In addition, RNF13 was detected in precancerous lesions： tubular complexes in chronic pancreatitis （CP） and pancreatic intraepithelial neoplasia （PanIN） （79.3%, 23/29 and 62.8%, 22/35, respectively）. Moreover, RNF13 staining was significantly correlated with Tenascin-C expression （P = 0.004） in PDAC samples, further supporting the role of RNF13 in cancer progression. Over-expression of wild type but not RING domain-mutant RNF13 in pancreatic MiaPaca-2 cancer cells increased invasive potential and gelatinolytic activity by matrix metalloproteinase-9. Taken together, these findings reveal that RNF13 is a novel E3 ubiquitin ligase involved in pancreatic carcinogenesis; ubiqui-tin-mediated modification of proteins by RNF13 may participate in pancreatic cancer development.

Softening response under undrained compression following anisotropic consolidation

Experimental evidence has indicated that clay exhibits strain-softening response under undrained compression following anisotropic consolidation.The purpose of this work was to propose a modeling method under critical state theory of soil mechanics.Based on experimental data on different types of clay,a simple double-surface model was developed considering explicitly the location of critical state by incorporating the density state into constitutive equations.The model was then used to simulate undrained triaxial compression tests performed on isotropically and anisotropically consolidated samples with different stress ratios.The predictions were compared with experimental results.All simulations demonstrate that the proposed approach is capable of describing the drained and undrained compression behaviors following isotropic and anisotropic consolidations.

Diatomic Gaseous Sulfur Obtained at Low Temperature Catalytic Decomposition of Hydrogen Sulfide

Experimental evidences of occurrence of gaseous diatomic sulfur produced in the low temperature catalytic decomposition of hydrogen sulfide 2 H2S ←→ 2 H2 ＋ S2 （g） are summarized. The S2 molecule is suggested to be in the ground triplet state. Analysis of literature data allows concluding that the S2 metastable singlet state is realized in the thermal dissociation of hydrogen sulfide and solid sulfur. Arguments in favor of the hypothesis are been discussed.

Is the Chinese Renminbi Undervalued？ An Examination of the B-S Effect Using Diverse Datasets

In 2010, the debate over valuation of the Renminbi is again heating up and the Chinese currency has returned to appreciating against the dollar But is the Renminbi undervalued？ Drawing on the Balassa-Samuelson （B-S） effect on purchasing power parity, we conduct theoretical and empirical analyses of this issue. Theoretical analysis proves that a country＇s real exchange rate will appreciate with rising income, but the currencies of low-income countries tend to be undervalued. In order to avoid biased conclusions resulting from a single dataset or sampling method, we draw on three major publicly-available datasets to examine the B-S effect across 144 economies. Our results indicate that the degree of Renminbi misvaluation is highly dependent on the data source. Synthesizing analyses of diverse datasets, we estimate that the Renminbi was only undervalued by less than 8per cent in 2009. We conclude that China＇s external imbalance most probably results from deep-seated structural imbalances rather than Renminbi undervaluation.

Determinants on Rural-Urban Labor Migration in China:Empirical Analysis on the Effect of Rural Cooperate Medical Insurance based on Cross-Sectional and Longitudinal Data

This paper studies factors influencing rural-urban labor migration in China,particularly the implementation of rural cooperative medical insurance(RCMI) in the year 2003.With the support of data analysis from the year 2000,2004 and 2006,clear linear correlations are found between gender,income,health condition and rural-urban labor flow,whereas the impact of education and employment status are more complicated.More importantly,results from regression show that the establishment of RCMI in countryside of China not only inhibits rural residents from seeking employment outside the village,but also pulls back rural people who have already worked in cities.When regional dimension is concerned,the pure composite effect of RCMI on rural labor flow is less significant in coastal areas with better economic performance and medical service.

The Empirical Analysis of the Impacts of Income Distribution Gap on Consumption Demand:Based on the Statistic Data of Chinese Urban Residents in 2000-2010

This paper analyzes the impact of income distribution gap on consumption demand from a theoretical view,and draws the conclusion that there is an inverse relationship between income distribution gap and consumption demand.Then,the paper finds that the existing widening income distribution gap in China has a negative impact on consumption demand,but this is not the key factor for the insufficient consumption demand because of the low level of per capital income.At last,it suggests that governments should improve the income level of entire residents and adjust income distribution structure simultaneously.

Common misconceptions about 5-aminosalicylates and thiopurines in inflammatory bowel disease

Misconceptions are common in the care of patients with inflammatory bowel disease(IBD).In this paper,we state the most commonly found misconceptions in clinical practice and deal with the use of 5-aminosalicylates and thiopurines,to review the related scientificevidence,and make appropriate recommendations.Prevention of errors needs knowledge to avoid making such errors through ignorance.However,the amount of knowledge is increasing so quickly that one new danger is an overabundance of information.IBD is a model of a very complex disease and our goal with this review is to summarize the key evidence for the most common daily clinical problems.With regard to the use of 5-aminosalicylates,the best practice may to be consider abandoning the use of these drugs in patients withsmall bowel Crohn's disease.The combined approach with oral plus topical 5-aminosalicylates should be the first-line therapy in patients with active ulcerative colitis;once-daily treatment should be offered as a first choice regimen due to its better compliance and higher efficacy.With regard to thiopurines,they seem to be as effective in ulcerative colitis as in Crohn's disease.Underdosing of thiopurines is a form of undertreatment.Thiopurines should probably be continued indefinitely because their withdrawal is associated with a high risk of relapse.Mercaptopurine is a safe alternative in patients with digestive intolerance or hepatotoxicity due to azathioprine.Finally,thiopurine methyltransferase(TPMT)screening cannot substitute for regular monitoring because the majority of cases of myelotoxicity are not TPMT-related.

CFD Simulation and Experimental Validation of Fluid Flow in Pre-distributor

Liquid distributor is a very import intemal for distillation columns. Pre-distributor is usually set on the top of distributor for initial distribution. Fluid flow in pre-distributor is a complex system of variable mass flow with many orifices and sub-branches. Consequently, the two phase modeling of pre-distributors was carried out andthe homogeneous model with free surface model was applied. The numerical method was validated by comparing with experimental data. Using the simulated results for different pre-distributors, the impacts of inflow rate, location and orientation uoon the outflow distribution were investigated. Furthermore, influences of the outflow distribution for pre-distributor on liquid uniformity in trough were also analyzed, The conclusions can De aaoptea for me structural design of liquid distributor and pre-distributor of large scale.

An Empirical Research on Mixed- Ownership Reform and SOE Innovation： Evidence from China＇s Industrial Enterprises

Using the microscopic data of China＇s industrial enterprises, this paper measures innovation efficiency by the sales revenue of new products as a share in total sales revenue, and examines SOE mixed ownership reform＇s innovation efficiency effect using PSM method under a ＂quasi-natural experiment＂ theoretical framework. Results indicate that： Mixed-ownership reform can significantly increase corporate innovation efficiency. Reformed SOEs are more efficient at innovation than foreign-funded firms, private firms and firms invested by Hong Kong, Macao and Taiwan. This paper provides robust evidence for evaluating SOt？ innovation performance after mixed-ownership reform, and offers policy implications for promoting SOE mixed-ownership reform.

A Pilot Study on the Effects of Temperature on the Blooms of the Benthic Mucilage-Forming Microalga Chrysophaeum taylorii

C. taylorii （Chrysophaeum taylorii） Lewis and Bryan （Pelagophyceae） are benthic mucilage-producing microalgae recently recorded in the Mediterranean Sea, where its summer blooms are having detrimental effects on benthic communities, fisheries and tourism, especially along the Sardinian coasts （western Mediterranean Sea）. Although few informations on the bloom dynamics of this microalga are available in literature jet, recent studies have hypothesized that sea water temperature plays a major role in determining the distribution and abundance of C. taylorii. The goal of this pilot study was to verify the above-mentioned statement providing experimental evidence for it. To this purpose, C. taylorii presence and abundance were investigated along a temperature gradient near the powerhouse of Torre Valdaliga （Latium coasts）, where a stream of hot water is continuously pumped out from the powerhouse into the sea. The obtained data showed that C. taylorii abundance was significantly higher in the study sites nearer to the powerhouse and a positive correlation between water temperature and cell densities was found, thus confirming that water temperature is one of the environmental variables directly influencing the bloom dynamics of this microalga in the Mediterranean Sea.

Energy intensity and its determinants in China:an empirical study based on ARDL-VECM approach

The present study aims to better understand the relationship between energy intensity and its determinants including energy price, technological progress, economic structure, and energy mix using the autoregressive distributed lag(ARDL) bounds approach and vector error correction model technique. Based on China's time series over 1985-2014, the ARDL bounds approach yields empirical evidence that confirms the existence of long run relationship between energy price, technological progress, economic structure, energy mix, and energy intensity. The results show that technological progress is an important driver for the declining energy intensity in short and long run. Energy price has not been demonstrated as an important role in decreasing energy intensity in the short run. The high share of coal use in total energy use may be responsible for China's high energy intensity.However, the relative change in economic sectors plays a minor role in energy intensity reduction during the past years. In the long run, technological progress, energy mix and energy prices Granger cause energy intensity, but not vice versa except for the energy mix.