目的：观察苯巴比妥高血浓度长期治疗急性脑炎伴难控制和反复发作癫痫（acuteencephalitis with refractory，repetitive partial seizures，AERRPS）患者的安全性。方法：2003年7月至2008年9月期间入院的脑炎患者，符合Sakuma于2001年...目的：观察苯巴比妥高血浓度长期治疗急性脑炎伴难控制和反复发作癫痫（acuteencephalitis with refractory，repetitive partial seizures，AERRPS）患者的安全性。方法：2003年7月至2008年9月期间入院的脑炎患者，符合Sakuma于2001年提出的AERRPS诊断标准的患者入组，给药方法：200mg苯巴比妥静脉推注或肌内注射后，再以1—1．5mg／（kg·h）静脉滴注或200mg肌内注射或静脉推注，每2—4h1次，每日总量在1．2～2．4g，使苯巴比妥血浓度在24h左右达到100μg/ml。维持时间24～100d。观察苯巴比妥高血浓度治疗时患者的血压、心率及心律、呼吸、皮肤反应、意识、瞳孔、癫痫发作情况，并进行血常规检查、生化分析及长程脑电图监测。预后观察至少6个月。结果：苯巴比妥高血浓度维持期间，5例患者均处于昏迷状态，格拉斯哥昏迷评分（GCS）3～5分，脑电图监测未见爆发-抑制模式。脑干反射大部分保留。自主呼吸全部消失。3例窦性心动过速，2例室性或室上性心动过速。2例血压下降至64～86／40—55mmHg。5例患者的ALT57～385IU／L，AST38—365IU／L，γ-GT54～542IU／L，血氨升高至103．7μmoL／L，皮肤不良反应很轻。肾功能未受影响。当苯巴比妥血浓度降至50μg/ml以下时，患者意识和自主呼吸恢复，不良反应基本消退。结论：苯巴比妥高血浓度长期治疗可能致严重不良反应，因此AERRPS患者使用苯巴比妥高血浓度长期治疗期间必须使用人工辅助呼吸，严密监测，并及时处理出现的不良反应，以利于患者安全。展开更多
Generally, Lock and Unlock statements are primitives that should be wholly imple- mented,i.e.,the test of lock state and the operation of locking must be executed continuously without being interrupted. Different f...Generally, Lock and Unlock statements are primitives that should be wholly imple- mented,i.e.,the test of lock state and the operation of locking must be executed continuously without being interrupted. Different from nmormal lock operations, the lock and Unlock algorithm Presented in this paper can be interrupted anywhere by other processes The value of the algorithm in the implementation of concurrent control and mutually-exclusive operations was elucidated with one application of the algorithm in a heterogeneous datedbase united system.展开更多
In order to effectively control the dust in the underground coal mine,this study proposes and develops a new technology for dust control by foam,and briefly demonstrates the advantage of the foam technology for dust c...In order to effectively control the dust in the underground coal mine,this study proposes and develops a new technology for dust control by foam,and briefly demonstrates the advantage of the foam technology for dust control,such as the good isolation performance,large contact area,high wetting ability,strong adhesion and so on.Besides,the details of the technology are introduced,including the foam agent,foam generator,and foam production process.Then the paper studies the relationship between the foaming agent concentration and liquid surface tension,and explains the principle of the foam generator.The technology is applied in heading face.The application results show that the foam has a remarkable effect on dust control in underground coal mines.展开更多
Purpose： This study aimed to investigate whether workload intensity modulates exercise-induced effect on reaction time （RT） performances, and more specifically to clarify whether cognitive control that plays a cruc...Purpose： This study aimed to investigate whether workload intensity modulates exercise-induced effect on reaction time （RT） performances, and more specifically to clarify whether cognitive control that plays a crucial role in rapid decision making is altered. Methods： Fourteen participants performed a Simon Task while cycling 20 min at a light （first ventilatory threshold, VT~ - 20%）, moderate （VTI）, or very hard （VTj ＋ 20%） level of exercise. Results： After 15 min of cycling, RTs are faster than during the first 5 min of exercise. This benefit does not fluctuate with the intensity of exercise and enlarges as RT lengthens. Despite a numerical difference suggesting a greater facilitation during moderate exercise （-16 ms） than during a light exercise （-10 ms）, the benefit is not statistically different. Interestingly, we did not observe any signs of worsening on RT or on accuracy during very hard exercise. Conclusion： Cognitive control is extremely robust and appears not to be affected by the intensity of exercise. The selective inhibition and the between-trials adjustments are effective from the beginning to the end of exercise, regardless of the workload output.展开更多
文摘目的：观察苯巴比妥高血浓度长期治疗急性脑炎伴难控制和反复发作癫痫（acuteencephalitis with refractory，repetitive partial seizures，AERRPS）患者的安全性。方法：2003年7月至2008年9月期间入院的脑炎患者，符合Sakuma于2001年提出的AERRPS诊断标准的患者入组，给药方法：200mg苯巴比妥静脉推注或肌内注射后，再以1—1．5mg／（kg·h）静脉滴注或200mg肌内注射或静脉推注，每2—4h1次，每日总量在1．2～2．4g，使苯巴比妥血浓度在24h左右达到100μg/ml。维持时间24～100d。观察苯巴比妥高血浓度治疗时患者的血压、心率及心律、呼吸、皮肤反应、意识、瞳孔、癫痫发作情况，并进行血常规检查、生化分析及长程脑电图监测。预后观察至少6个月。结果：苯巴比妥高血浓度维持期间，5例患者均处于昏迷状态，格拉斯哥昏迷评分（GCS）3～5分，脑电图监测未见爆发-抑制模式。脑干反射大部分保留。自主呼吸全部消失。3例窦性心动过速，2例室性或室上性心动过速。2例血压下降至64～86／40—55mmHg。5例患者的ALT57～385IU／L，AST38—365IU／L，γ-GT54～542IU／L，血氨升高至103．7μmoL／L，皮肤不良反应很轻。肾功能未受影响。当苯巴比妥血浓度降至50μg/ml以下时，患者意识和自主呼吸恢复，不良反应基本消退。结论：苯巴比妥高血浓度长期治疗可能致严重不良反应，因此AERRPS患者使用苯巴比妥高血浓度长期治疗期间必须使用人工辅助呼吸，严密监测，并及时处理出现的不良反应，以利于患者安全。
文摘Generally, Lock and Unlock statements are primitives that should be wholly imple- mented,i.e.,the test of lock state and the operation of locking must be executed continuously without being interrupted. Different from nmormal lock operations, the lock and Unlock algorithm Presented in this paper can be interrupted anywhere by other processes The value of the algorithm in the implementation of concurrent control and mutually-exclusive operations was elucidated with one application of the algorithm in a heterogeneous datedbase united system.
基金The financial support by the National Natural Science Foundation of China (No.51104153)the Fundamental Research Fundsfor the Central Universities (No.2011QNB11)
文摘In order to effectively control the dust in the underground coal mine,this study proposes and develops a new technology for dust control by foam,and briefly demonstrates the advantage of the foam technology for dust control,such as the good isolation performance,large contact area,high wetting ability,strong adhesion and so on.Besides,the details of the technology are introduced,including the foam agent,foam generator,and foam production process.Then the paper studies the relationship between the foaming agent concentration and liquid surface tension,and explains the principle of the foam generator.The technology is applied in heading face.The application results show that the foam has a remarkable effect on dust control in underground coal mines.
基金supported by a grant from the French Research Agency (ANR 2013-069)
文摘Purpose： This study aimed to investigate whether workload intensity modulates exercise-induced effect on reaction time （RT） performances, and more specifically to clarify whether cognitive control that plays a crucial role in rapid decision making is altered. Methods： Fourteen participants performed a Simon Task while cycling 20 min at a light （first ventilatory threshold, VT~ - 20%）, moderate （VTI）, or very hard （VTj ＋ 20%） level of exercise. Results： After 15 min of cycling, RTs are faster than during the first 5 min of exercise. This benefit does not fluctuate with the intensity of exercise and enlarges as RT lengthens. Despite a numerical difference suggesting a greater facilitation during moderate exercise （-16 ms） than during a light exercise （-10 ms）, the benefit is not statistically different. Interestingly, we did not observe any signs of worsening on RT or on accuracy during very hard exercise. Conclusion： Cognitive control is extremely robust and appears not to be affected by the intensity of exercise. The selective inhibition and the between-trials adjustments are effective from the beginning to the end of exercise, regardless of the workload output.
