Background It is debatable whether treating multimorbid nursing home patients with antihypertensive drugs produces beneficial effects. Most cardiovascular guidelines promote treatment; few have advice on how to depres...Background It is debatable whether treating multimorbid nursing home patients with antihypertensive drugs produces beneficial effects. Most cardiovascular guidelines promote treatment; few have advice on how to deprescribe when treatment may no longer be necessary. We investigated the effect of medication review on antihypertensive drug use and the association between cognition, blood pressure, and prescribing. Methods From August 2014 to December 2015, 765 patients from 72 units （clusters） in 32 Norwegian nursing homes were included in a 4-month, multicentre, cluster-randomized, controlled trial, with 9-month follow-up. Patients ≥ 65 years old with antihypertensive treatment （n = 295, 39%） were randomized to systematic medication review where the physician received support from peers （collegial mentoring） or were given care as usual （control condition）. Outcome measures were the number of antihypertensive drugs, systolic blood pressure, and pulse. We used hospitalizations and deaths as criteria to assess harm. Results At baseline, each patient used 9.2 ± 3.5 regular drugs, and 1.6 ± 0.7 antihypertensives. Mean blood pressure was 128/71 mmHg and 9% had a systolic pressure ≥ 160 mmHg. Between baseline and month four, antihypertensives were deprescribed to a significantly higher extent in the intervention group （n = 43, 32%） compared to control （n = 11, 10%）; Incidence Rate Ratio = 0.8, 95% CI = 0.7？0.9. In the intervention group, there was an immediate increase in systolic blood pressure when antihypertensives were reduced, from baseline 128 ± 19.5 mmHg to 143 ± 25.5 mmHg at month four. However, at month nine, the blood pressure had reverted to baseline values （mean 134 mmHg）. Deprescription did not affect pulse and systolic pressure. The number of hospitalizations was higher in control patients at month four （P = 0.031） and nine （P = 0.041）. Conclusion A systematic medication review supported by collegial mentoring significantly decreased the use of antihypertensive drugs in nursing home patients without an effect on the systolic blood pressure over time.展开更多
With the increase of network complexity,the flexibility of network control and management becomes a nontrivial problem.Both Software Defined Network(SDN) and Autonomic Network technologies are sophisticated technologi...With the increase of network complexity,the flexibility of network control and management becomes a nontrivial problem.Both Software Defined Network(SDN) and Autonomic Network technologies are sophisticated technologies for the network control and management.These two technologies could be combined together to construct a software defined self-managing solution for the future network.An autonomic QoS management mechanism in Software Defined Network(AQSDN) is proposed in this paper.In AQSDN,the various QoS features can be configured autonomically in an OpenFlow switch through extending the OpenFlow and OF-Config protocols.Based on AQSDN,a novel packet context-aware QoS model(PCaQoS) is also introduced for improving the network QoS.PCaQoS takes packet context into account when packet is marked and managed into forwarding queues.The implementation of a video application's prototype which evaluates the self-configuration feature of the AQSDN and the enhancement ability of the PCaQoS is presented in order to validate this design.展开更多
Base on the theory of energy minimization, a numerical algorithm is established to calculate load distribution, and the relationship curve of spur gear load distribution is obtained, and the load distribution ratio ch...Base on the theory of energy minimization, a numerical algorithm is established to calculate load distribution, and the relationship curve of spur gear load distribution is obtained, and the load distribution ratio changes from 033 to 067 in double contact zone. This theory is adopted to compute the load distribution of helical gear along time-varying contact line, and the load distribution varies with the instantaneous position of the meshing point and the length of contact line, and the maximum value of load appears at the pitch point. Compared with the load distribution results, the helical gear changes more smoothly than spur gear. The load distribution provides a basis for calculate tooth bending deformation and critical stress.展开更多
Permanent Magnet Synchronous Motor model can exhibit a variety of chaotic phenomena under some choices of system parameters and external input. Based on the property of passive system, the essential conditions were st...Permanent Magnet Synchronous Motor model can exhibit a variety of chaotic phenomena under some choices of system parameters and external input. Based on the property of passive system, the essential conditions were studied, by which Permanent Magnet Synchronous Motor chaotic system could be equivalent to passive system. Using Lyapunov stability theory, the convergence condition deciding the system's characters was discussed. In the convergence condition area, the equivalent passive system could be globally asymptotically stabilized by smooth state feedback.展开更多
In order to solve the problem of artificial generation and low efficiency of test sequences for zone controller (ZC), a model-based automatic generation method of test sequence is proposed. Firstly, the timed automata...In order to solve the problem of artificial generation and low efficiency of test sequences for zone controller (ZC), a model-based automatic generation method of test sequence is proposed. Firstly, the timed automata model is established based on function analysis of the zone controller, and the correctness of the model is verified by UPPAAL. Then by parsing the timed automata model files, state information and transition conditions can be extracted to generate test case sets. Finally, according to the serialization conditions of test cases, the test cases are serialized into test sequences by using the improved depth first search algorithm. A case, the ZC controls the train running within its jurisdiction, shows that the method is correct and can effectively improve the efficiency of test sequence generation.展开更多
Most of data distribution mechanism in Opportunistic Networks is derived by Epidemic data distribution,and Epidemic data distribution means that when each node meets another node,it may copy its own messages and trans...Most of data distribution mechanism in Opportunistic Networks is derived by Epidemic data distribution,and Epidemic data distribution means that when each node meets another node,it may copy its own messages and transfer to another node.On the one hand,the copies improve the forwarding rate,and reduce the transmission delay.However,on the other hand,energy consumption increases and network survival time is reduced because the copies consume transmission resource.Therefore,copy number should be under control.In this paper,we first introduce the existing routing strategy based on Epidemic briefly,and present the Epidemic routing protocol analysis model and copy control mechanism based on the limited Epidemic in Opportunistic Networks.Then based on the limited copies scheme(LCS),we propose an energy balance scheme(EBS),the results show that EBS can improve the network survival time.展开更多
Although the modeling technologies for open robot controllers have been discussed widely, not much literature is devoted to the actual general modeling principles and strategies. The reason is that many researches foc...Although the modeling technologies for open robot controllers have been discussed widely, not much literature is devoted to the actual general modeling principles and strategies. The reason is that many researches focus on specific application fields. This paper accommodates for this lacuna and provides some general modeling principles and strategies. At last, the actual new modeling method Hierarchical Object Oriented Petri net (HOONet) which has been proved to be an effective modeling methodology, is used to illustrate the modeling strategies.展开更多
Taking a specific production process as an example, this paper introduces the design of multi slot and unequal temperature PID controller based on single chip microcomputer. The mathematical implementation method...Taking a specific production process as an example, this paper introduces the design of multi slot and unequal temperature PID controller based on single chip microcomputer. The mathematical implementation method of PID algorithm and the design method of the hardware and software are discussed, The principle diagram of the hardware circuit implementing the control algorithm and the features of the software possessed are also presented.展开更多
Public security emergency is a public crisis event, and we cannot anticipate the specific time, actual scale, specific situation and influence depth of emergencies. If the emergencies are not under control, the crisis...Public security emergency is a public crisis event, and we cannot anticipate the specific time, actual scale, specific situation and influence depth of emergencies. If the emergencies are not under control, the crisis will get worse and its destructive energy will be released quickly.Structure box is an invisible closed system which is constructed by local politics, economy, and culture. Namely, structure box is local social ecological environment. Structure box is a closed area which is full of anger. Therefore, in such environment with too much pressure, we need an outlet to release pressure. Anger is the social and psychological basis of the emotional resonance of onlooker, when the fuse incident occurred, so that the widespread anger in structure box will find the spotlight. The words and actions of the leaders in the informal group will produce a great social infection and circulatory response, and groups’ stirring will cause emotional resonance which is easy to burst. Thus, irrational behavior may caused by people. This processcan use five links to describe： occurrence of fuse events, information diffusion, emotional resonance, situational catalysis, control failure, and occurrence of public security emergency. This is the occurrence mechanism of public security emergency.展开更多
The simple dynamic model is often adopted to deal with control questions in research on semi-active suspension. The model has more theoretic meanings than authentic ones because of difference between practical and phy...The simple dynamic model is often adopted to deal with control questions in research on semi-active suspension. The model has more theoretic meanings than authentic ones because of difference between practical and physical models. The virtual prototype has remarkable advantages in its application simulation processes. It is not only faster and more veracious, but also of better visualization of the simulation results.展开更多
This study focused on the automatic versus controlled nature of the underlying cognitive processes of ERPs （Event-Related Potentials） effects during speech perception. ERPs to the final word of sentences （half bein...This study focused on the automatic versus controlled nature of the underlying cognitive processes of ERPs （Event-Related Potentials） effects during speech perception. ERPs to the final word of sentences （half being semantically incongruent with the sentence and half congruent） were presented to French natives under 4 levels of degradation： no degradation, mild degradation （2 levels）, and strong degradation. Under mild degradation allowing controlled sentence-level processing according to behavioral data, the N400 effect （i.e., the N400 to incongruent words minus the N400 to congruent words） and a late positive complex were delayed and the latter effect was reduced. Under strong degradation allowing only automatic sentence processing according to behavioral data, no ERP effects remained. These results suggest that, unlike contextual effect found with single words （e.g., using word-pair or word-list paradigms）, ERP effects elicited by more complex contexts such as full sentences are generated by controlled but not by automatic mechanisms of speech processing.展开更多
Nowadays the flexible configuration of manufacturing cells becomes to an important requirement especially at small and medium sized companies. This method can make the production fast and effective at small series or ...Nowadays the flexible configuration of manufacturing cells becomes to an important requirement especially at small and medium sized companies. This method can make the production fast and effective at small series or frequent manufacturing changes. The shop-floor control method, presented in this paper, offers a solution for the facing problem of fast and easy reconfiguration. The hardware of the controller designed modular with software components for online configuration. This solution allows sensor integration on different levels for every part of the manufacturing cell. With unified programming language and the machine specific controllers （post-processing） the cells can be defined easily by different types of human-machine interaction. The shop-floor control architecture is implemented and validated on an Adept SCARA （selective compliance assembly robot arm） robot. The robot is driven by standalone, low-level, interchangeable, software and hardware components.展开更多
文摘Background It is debatable whether treating multimorbid nursing home patients with antihypertensive drugs produces beneficial effects. Most cardiovascular guidelines promote treatment; few have advice on how to deprescribe when treatment may no longer be necessary. We investigated the effect of medication review on antihypertensive drug use and the association between cognition, blood pressure, and prescribing. Methods From August 2014 to December 2015, 765 patients from 72 units （clusters） in 32 Norwegian nursing homes were included in a 4-month, multicentre, cluster-randomized, controlled trial, with 9-month follow-up. Patients ≥ 65 years old with antihypertensive treatment （n = 295, 39%） were randomized to systematic medication review where the physician received support from peers （collegial mentoring） or were given care as usual （control condition）. Outcome measures were the number of antihypertensive drugs, systolic blood pressure, and pulse. We used hospitalizations and deaths as criteria to assess harm. Results At baseline, each patient used 9.2 ± 3.5 regular drugs, and 1.6 ± 0.7 antihypertensives. Mean blood pressure was 128/71 mmHg and 9% had a systolic pressure ≥ 160 mmHg. Between baseline and month four, antihypertensives were deprescribed to a significantly higher extent in the intervention group （n = 43, 32%） compared to control （n = 11, 10%）; Incidence Rate Ratio = 0.8, 95% CI = 0.7？0.9. In the intervention group, there was an immediate increase in systolic blood pressure when antihypertensives were reduced, from baseline 128 ± 19.5 mmHg to 143 ± 25.5 mmHg at month four. However, at month nine, the blood pressure had reverted to baseline values （mean 134 mmHg）. Deprescription did not affect pulse and systolic pressure. The number of hospitalizations was higher in control patients at month four （P = 0.031） and nine （P = 0.041）. Conclusion A systematic medication review supported by collegial mentoring significantly decreased the use of antihypertensive drugs in nursing home patients without an effect on the systolic blood pressure over time.
基金This work was supported in part by the National High Technology Research and Development Program （863 Program） of China under Grant No. 2011AA01A101, No.2013AA013303, No.2013AA013301and National Natural science foundation of China No. 61370197 ＆ 61271041.
文摘With the increase of network complexity,the flexibility of network control and management becomes a nontrivial problem.Both Software Defined Network(SDN) and Autonomic Network technologies are sophisticated technologies for the network control and management.These two technologies could be combined together to construct a software defined self-managing solution for the future network.An autonomic QoS management mechanism in Software Defined Network(AQSDN) is proposed in this paper.In AQSDN,the various QoS features can be configured autonomically in an OpenFlow switch through extending the OpenFlow and OF-Config protocols.Based on AQSDN,a novel packet context-aware QoS model(PCaQoS) is also introduced for improving the network QoS.PCaQoS takes packet context into account when packet is marked and managed into forwarding queues.The implementation of a video application's prototype which evaluates the self-configuration feature of the AQSDN and the enhancement ability of the PCaQoS is presented in order to validate this design.
基金Sponsored by the Eleventh Five-years Drive for Basic Research Project
文摘Base on the theory of energy minimization, a numerical algorithm is established to calculate load distribution, and the relationship curve of spur gear load distribution is obtained, and the load distribution ratio changes from 033 to 067 in double contact zone. This theory is adopted to compute the load distribution of helical gear along time-varying contact line, and the load distribution varies with the instantaneous position of the meshing point and the length of contact line, and the maximum value of load appears at the pitch point. Compared with the load distribution results, the helical gear changes more smoothly than spur gear. The load distribution provides a basis for calculate tooth bending deformation and critical stress.
基金Project supported by the National Natural Science Foundation of China (No. 60374013) and the Natural Science Foundation of Zhejiang Province (No. M603217), China
文摘Permanent Magnet Synchronous Motor model can exhibit a variety of chaotic phenomena under some choices of system parameters and external input. Based on the property of passive system, the essential conditions were studied, by which Permanent Magnet Synchronous Motor chaotic system could be equivalent to passive system. Using Lyapunov stability theory, the convergence condition deciding the system's characters was discussed. In the convergence condition area, the equivalent passive system could be globally asymptotically stabilized by smooth state feedback.
文摘In order to solve the problem of artificial generation and low efficiency of test sequences for zone controller (ZC), a model-based automatic generation method of test sequence is proposed. Firstly, the timed automata model is established based on function analysis of the zone controller, and the correctness of the model is verified by UPPAAL. Then by parsing the timed automata model files, state information and transition conditions can be extracted to generate test case sets. Finally, according to the serialization conditions of test cases, the test cases are serialized into test sequences by using the improved depth first search algorithm. A case, the ZC controls the train running within its jurisdiction, shows that the method is correct and can effectively improve the efficiency of test sequence generation.
基金supported by the National Natural Science Foundation of China(61171097)Key Lab of Information Network Security, Ministry of Public Security(C14613)
文摘Most of data distribution mechanism in Opportunistic Networks is derived by Epidemic data distribution,and Epidemic data distribution means that when each node meets another node,it may copy its own messages and transfer to another node.On the one hand,the copies improve the forwarding rate,and reduce the transmission delay.However,on the other hand,energy consumption increases and network survival time is reduced because the copies consume transmission resource.Therefore,copy number should be under control.In this paper,we first introduce the existing routing strategy based on Epidemic briefly,and present the Epidemic routing protocol analysis model and copy control mechanism based on the limited Epidemic in Opportunistic Networks.Then based on the limited copies scheme(LCS),we propose an energy balance scheme(EBS),the results show that EBS can improve the network survival time.
文摘Although the modeling technologies for open robot controllers have been discussed widely, not much literature is devoted to the actual general modeling principles and strategies. The reason is that many researches focus on specific application fields. This paper accommodates for this lacuna and provides some general modeling principles and strategies. At last, the actual new modeling method Hierarchical Object Oriented Petri net (HOONet) which has been proved to be an effective modeling methodology, is used to illustrate the modeling strategies.
文摘Taking a specific production process as an example, this paper introduces the design of multi slot and unequal temperature PID controller based on single chip microcomputer. The mathematical implementation method of PID algorithm and the design method of the hardware and software are discussed, The principle diagram of the hardware circuit implementing the control algorithm and the features of the software possessed are also presented.
文摘Public security emergency is a public crisis event, and we cannot anticipate the specific time, actual scale, specific situation and influence depth of emergencies. If the emergencies are not under control, the crisis will get worse and its destructive energy will be released quickly.Structure box is an invisible closed system which is constructed by local politics, economy, and culture. Namely, structure box is local social ecological environment. Structure box is a closed area which is full of anger. Therefore, in such environment with too much pressure, we need an outlet to release pressure. Anger is the social and psychological basis of the emotional resonance of onlooker, when the fuse incident occurred, so that the widespread anger in structure box will find the spotlight. The words and actions of the leaders in the informal group will produce a great social infection and circulatory response, and groups’ stirring will cause emotional resonance which is easy to burst. Thus, irrational behavior may caused by people. This processcan use five links to describe： occurrence of fuse events, information diffusion, emotional resonance, situational catalysis, control failure, and occurrence of public security emergency. This is the occurrence mechanism of public security emergency.
文摘The simple dynamic model is often adopted to deal with control questions in research on semi-active suspension. The model has more theoretic meanings than authentic ones because of difference between practical and physical models. The virtual prototype has remarkable advantages in its application simulation processes. It is not only faster and more veracious, but also of better visualization of the simulation results.
文摘This study focused on the automatic versus controlled nature of the underlying cognitive processes of ERPs （Event-Related Potentials） effects during speech perception. ERPs to the final word of sentences （half being semantically incongruent with the sentence and half congruent） were presented to French natives under 4 levels of degradation： no degradation, mild degradation （2 levels）, and strong degradation. Under mild degradation allowing controlled sentence-level processing according to behavioral data, the N400 effect （i.e., the N400 to incongruent words minus the N400 to congruent words） and a late positive complex were delayed and the latter effect was reduced. Under strong degradation allowing only automatic sentence processing according to behavioral data, no ERP effects remained. These results suggest that, unlike contextual effect found with single words （e.g., using word-pair or word-list paradigms）, ERP effects elicited by more complex contexts such as full sentences are generated by controlled but not by automatic mechanisms of speech processing.
文摘Nowadays the flexible configuration of manufacturing cells becomes to an important requirement especially at small and medium sized companies. This method can make the production fast and effective at small series or frequent manufacturing changes. The shop-floor control method, presented in this paper, offers a solution for the facing problem of fast and easy reconfiguration. The hardware of the controller designed modular with software components for online configuration. This solution allows sensor integration on different levels for every part of the manufacturing cell. With unified programming language and the machine specific controllers （post-processing） the cells can be defined easily by different types of human-machine interaction. The shop-floor control architecture is implemented and validated on an Adept SCARA （selective compliance assembly robot arm） robot. The robot is driven by standalone, low-level, interchangeable, software and hardware components.
