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推拿加温针灸对膝骨性关节炎患者IL-1β、TNF-α的影响及临床疗效观察 被引量:14
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作者 林远方 朱其广 +2 位作者 曹亚飞 佘瑞涛 李成日 《中国中医骨伤科杂志》 CAS 2012年第7期24-26,29,共4页
目的:观察推拿加温针灸对膝骨性关节炎患者血清IL-1β、TNF-α表达的影响及临床疗效,阐明其作用及机理,为临床提供客观依据。方法:采用单盲、随机、对照研究方法,将合格受试者随机分为治疗组及对照组各50例。治疗组采用推拿加温针灸治疗... 目的:观察推拿加温针灸对膝骨性关节炎患者血清IL-1β、TNF-α表达的影响及临床疗效,阐明其作用及机理,为临床提供客观依据。方法:采用单盲、随机、对照研究方法,将合格受试者随机分为治疗组及对照组各50例。治疗组采用推拿加温针灸治疗,对照组采用TDP灯照射加普通针刺治疗,观察两组患者治疗前后的Lequesne指数评分等多维效应指标,评价临床疗效及安全性;同时比较两组患者治疗前后的血清IL-1β、TNF-α的变化。结果:治疗组的总有效率高于对照组(P<0.05),痊愈率和愈显率亦明显高于对照组,治疗组的起效时间及平均治疗次数明显少于对照组(P<0.01),并且安全;治疗组与对照组治疗后的IL-1β、TNF-α水平均较治疗前降低(P<0.01和P<0.05),而治疗组下降尤为明显(P<0.01)。结论:推拿加温针灸是一种起效快、疗程短、效好且安全的治疗膝骨性关节炎的好方法,值得临床推广应用,其作用机制可能与降低IL-1β、TNF-α水平有关。 展开更多
关键词 IL-1β 血清 TNF-α 血清 膝关节骨性关节炎 推拿、温针灸 中医疗法 临床研究
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Therapeutic observation of warm needling moxibustion plus tuina for knee osteoarthritis due to cold-dampness blocking collaterals 被引量:9
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作者 Wang Feng Li Ming-gang +2 位作者 Liu Gang Zhao Kun Li Fei 《Journal of Acupuncture and Tuina Science》 CSCD 2017年第1期54-58,共5页
Objective: To observe the clinical efficacy of warm needling moxibustion plus tuina in treating knee osteoarthritis (KOA) due to cold-dampness blocking collaterals. Methods: Forty-eight KOA patients were randomize... Objective: To observe the clinical efficacy of warm needling moxibustion plus tuina in treating knee osteoarthritis (KOA) due to cold-dampness blocking collaterals. Methods: Forty-eight KOA patients were randomized into 2 groups by their visiting sequence, 24 cases in each group. The treatment group was intervened by warm needling moxibustion plus tuina, while the control group was treated with acupuncture plus tuina. The two groups were both treated once a day, 30 min for each session, 10 d as a treatment course, totally for 3 treatment courses. The visual analogue scale (VAS) and Lysholm knee scoring scale (LKSS) were observed before and after the treatment to evaluate the clinical efficacy. Results: After 3 treatment courses, the VAS and LKSS scores were significantly changed in the two groups (P〈0.01), and the between-group differences were also statistically significant (P〈0.01). The markedly-effective rate was 83.3% in the treatment group versus 66.7% in the control group, and the difference was statistically significant (P〈0.05). Conclusion: Warm needling moxibustion plus tuina can produce a more significant efficacy than acupuncture plus tuina in treating KOA due to cold-dampness blocking collaterals. 展开更多
关键词 Acupuncture Therapy Moxibustion Therapy Warm Needling Therapy TUINA MASSAGE Osteoarthritis Knee Visual Analog Scale Pain Measurement
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