针灸与推拿治法联合治疗脑梗死临床疗效观察

目的:分析针灸与推拿治法联合治疗脑梗死临床疗效。方法:将2016年1月-2017年3月78例脑梗死患者作为研究对象并根据随机数字表分组,分别39例。A组采用针灸治疗,B组采用针灸与推拿治法联合治疗。比较两组脑梗死治疗总有效率;不良反应发生率;干预前后患者神经功能缺损评分、BI指数、肌力评分。结果:B组脑梗死治疗总有效率高于A组,P<0.05;B组不良反应发生率和A组相近,P>0.05;干预前两组神经功能缺损评分、BI指数、肌力评分相近,P>0.05;干预后B组神经功能缺损评分、BI指数、肌力评分优于A组,P<0.05。结论:针灸与推拿治法联合治疗脑梗死临床疗效确切,可有效改善患者神经组织功能和肢体运动功能,提升生活自理能力,无明显不良反应,值得推广。

针灸与推拿治法联合治疗脑梗死的效果观察及不良反应发生率影响分析

目的:研究针灸联合推拿治法对脑梗死患者的治疗效果及不良反应发生情况的影响.方法:此次研究起始与结束时间分别为2017年1月和2019年6月,在此期间内随机68例患者作为观察对象,患者均于研究时间内在我院就诊,确诊为脑梗死后均在我院接受治疗.将治疗方法为分组依据,以随机数字法对患者进行编号,单数患者纳入对照组,双数患者纳入观察组.对照组患者以针灸方法进行治疗,观察组患者以针灸联合推拿治法进行治疗,对比两组治疗前后FM(肢体运动功能量表)、ADL(生活能力量表)评分,同时统计两组患者在治疗期间不良反应的发生情况.结果:治疗前,患者组间FM、ADL评分不存在统计学差异(P>0.05),治疗结束后,均得到了显著改善,且观察组显著优于对照组(P<0.05);对照组2例患者出现皮肤发红的不良反应,发生率为5.88%,观察组3例患者出现不良反应,发生率为8.82%,观察组略高于对照组,但组间不存在统计学差异(P>0.05).结论:对于脑梗死患者的临床治疗来说,针灸联合推拿治法的实施有着较好的效果,并且不会导致患者出现严重的不良反应,因此,值得在临床上进行推广及应用.

Therapeutic efficacy observation of warm needling moxibustion plus spine subtle adjusting manipulation for cervical radiculopathy

Objective To observe the clinical efficacy of warm needling moxibustion plus spine subtle adjusting manipulation for cervical radiculopathy.Methods A total of 70 patients with cervical radiculopathy were randomized into an observation group and a control group,with 35 cases in each group.The observation group was treated with warm needling moxibustion plus spine subtle adjusting manipulation,while the control group was treated with warm needling moxibustion alone.The treatments were performed three times a week,and for four weeks in total.The visual analog scale(VAS)was scored before and after treatment.And the clinical efficacy of the two groups was compared after treatment.Results The total effective rate was 97.1%in the observation group,versus 88.6%in the control group.The difference between the two groups was statistically significant(P<0.05).After treatment,the VAS scores in both groups significantly decreased(P<0.01),and the score in the observation group was significantly lower than that in the control group(P<0.05).Conclusion Warm needling moxibustion plus spine subtle adjusting manipulation has a better effect in the treatment of cervical radiculopathy than warm needling moxibustion alone.

Treatment of 18 Cases of Chronic Prostatitis by Acupuncture plus Tuina Therapy

In the treatment of 18 cases of prostatitis by puncturing Shenshu （BL 23）,bilateral Sanyinjiao （SP 6） and Zusanli （ST 36） and by kneading the prostate via the anus after acupuncture, the results showed cure in 12 cases, improvement in 5 cases, failure in 1 case and the total effective rate in 94.4%.

Effects of sinew-regulating bone-setting manipulations on chondrocytes,IL-1βand NO in rabbits with knee osteoarthritis

Objective To observe the therapeutic effect of sinew-regulating bone-setting manipulations for knee osteoarthritis(KOA)model rabbits and its impacts on the chondrocyte apoptosis rate and the levels of interleukin(IL)-1βand nitric oxide(NO).Methods According to the random number table method,30 New Zealand white rabbits were divided into a normal group(n=9)and a modeling group(n=21).Rabbits in the modeling group were used to establish KOA models with the modified Hulth method.At the 8th week,three rabbits were sacrificed to verify the model and the remaining 18 rabbits were randomly divided into a model group(n=9)and an intervention group(n=9).Rabbits in the normal group and model group were bred routinely without any intervention.Rabbits in the intervention group were treated with the sinew-regulating bone-setting manipulations,10 min/time,once every other day for a total of 20 times.The Lequesne MG knee function rating was used to evaluate the behavioral differences of the rabbits in each group.The Pelletier score was used to evaluate the general changes of the rabbits.The Mankin score was used to evaluate the pathology of knee cartilages.The enzyme-linked immunosorbent assay and nitrate reductase methods were used to determine the levels of IL-1βand NO in serum and synovial fluid of each group,respectively.In situ terminal deoxynucleotidyl transferase-mediated nick and labeling method was used to determine the apoptosis of chondrocytes in each group.Results Compared with the normal group,the scores of Lequesne MG,Pelletier and Mankin,and the levels of IL-1βand NO in the model group were increased(P<0.05),which indirectly indicated the success of the model.Compared with the model group,the scores of Lequesne MG,Pelletier and Mankin,IL-1βand NO levels,and chondrocyte apoptosis rate of the intervention group were decreased,and the differences were statistically significant(P<0.05).Conclusion The sinew-regulating bone-setting manipulations can reduce the levels of IL-1β,NO,and chondrocyte apoptosis rate,and delay the articular cartilage degeneration,therefore,having a good therapeutic effect on KOA.

Protocol-optimizing study of combining Tuina and horse-riding squat exercise for knee osteoarthritis

Objective To evaluate the efficacy of Tuina(Chinese therapeutic massage)manipulation plus horse-riding squat exercise in treating knee osteoarthritis(KOA)and optimize the combining protocol.Methods Based on a 2×2 factorial design,120 eligible KOA patients were randomized into a manipulation group(group A1B2),a manipulation plus horse-riding squat group(group A1B1),a sitting knee-adjustment group(group A2B2 group),and a sitting knee-adjustment plus horse-riding squat group(group A2B1),with 30 cases in each group.The intervention was conducted three times a week,lasting for four weeks.The Western Ontario and McMaster Universities osteoarthritis index(WOMAC)was taken as the major measure for efficacy evaluation(including three component scores,pain,stiffness,and daily function,and total score).Results The three component scores(pain,stiffness,and daily function)and the total score of WOMAC showed significant differences after the intervention in the four groups(P<0.05).There were significant inter-group differences in the WOMAC stiffness score amongst the four groups after the intervention(P<0.05).In group A1B1,the step length,stride,walking speed,and knee joint flexion angle changed significantly after treatment(P<0.05).After the intervention,the step length changed significantly in group A1B2(P<0.05),and the walking speed changed significantly in group A2B1(P<0.05).There were no significant differences in the step length,stride,walking speed,or knee joint flexion angle among the four groups(P>0.05).The extensor peak torque at 180°/s changed significantly in group A1B2 after treatment(P<0.05).Neither the intra-group nor the inter-group comparisons of the four groups revealed significant differences in the other isokinetic muscle strength parameters(P>0.05).The main effect of manipulation showed significant in affecting the WOMAC pain and total scores(P<0.05).The main effect of horse-riding squat exercise showed significant in affecting the WOMAC pain and stiffness scores(P<0.05).Conclusion The four treatment protocols all can improve the symptoms of KOA,for instance,relieving pain and stiffness,and enhancing daily function.Group A2B1 produces the most eminent effect in relieving joint stiffness.The main effects of both manipulation and horse-riding squat exercise are significant in reducing pain.Besides,the main effect of horse-riding squat exercise is significant in relieving joint stiffness.

Clinical efficacy observation of spine subtle adjusting manipulation for postpartum low back pain

Objective To explore the clinical efficacy of spine subtle adjusting manipulation for postpartum low back pain(PLBP).Methods A total of 76 patients with PLBP were randomized into a control group and a treatment group,with 38 cases in each group.The control group was treated with core muscle strengthening exercises,and the treatment group was treated with spine subtle adjusting manipulation.After 3 weeks of treatment,the clinical efficacy was observed,and the visual analog scale(VAS)score and Oswestry disability index(ODI),and the changes of lumbar Cobb angle and pelvic rotation were compared between the two groups.Results The total effective rate of the treatment group was 92.1%,and that of the control group was 78.9%.The difference between the two groups was statistically significant(P<0.05).After treatment,the VAS score and ODI in both groups decreased,and the intra-group differences were all statistically significant(P<0.05).There were no intra-group statistical differences in the lumbar Cobb angle or pelvic rotation in the two groups(P>0.05).After treatment,there were no statistical differences in the lumbar Cobb angle or pelvic rotation between the two groups(P>0.05);the VAS score and ODI in the treatment group were significantly lower than those in the control group(P<0.05).Conclusion Spine subtle adjusting manipulation can effectively relieve the pain for patients with PLBP,and improve their daily activity function.

Efficacy of knee-balancing manipulation plus heat-sensitive moxibustion for knee osteoarthritis and its influence on CTX-Ⅰ,TRACP-5b,ADAMTS-4,and MMP-3

Objective To observe the efficacy of knee-balancing manipulation plus heat-sensitive moxibustion in treating knee osteoarthritis(KOA)and its impact on the expression of C-telopeptide of type I collagen(CTX-Ⅰ),tartrate-resistant acid phosphatase 5b(TRACP-5b),A disintegrin and metalloproteinase with thrombospondin motifs 4(ADAMTS-4),and matrix metalloproteinase 3(MMP-3).Methods A total of 134 unilateral KOA patients were randomized into a knee-balancing group,a heat-sensitive moxibustion group,and a joint intervention group.The knee-balancing group received knee-balancing Tuina(Chinese therapeutic massage)manipulation for treatment.The heat-sensitive moxibustion group received heat-sensitive moxibustion treatment.The joint intervention group received the heat-sensitive moxibustion in addition to the knee-balancing manipulation.The intervention period lasted for four weeks.After the treatment,and at the 2-week and 6-week follow-ups,the three groups were assessed using the visual analog scale(VAS)for knee joint pain and Western Ontario and McMaster Universities arthritis index(WOMAC),and clinical efficacy was also evaluated.The enzyme-linked immunosorbent assay was adopted to detect the expression levels of serum CTX-Ⅰ,TRACP-5b,ADAMTS-4,and MMP-3.Results The knee-balancing group had 44 participants,but one dropped out;there was no dropout case among the 44 participants in the heat-sensitive moxibustion group;among the 46 participants in the joint intervention group,two cases dropped out.After the treatment,and at the 2-week and 6-week follow-ups,the total effective rate was found higher in the joint intervention group than in the knee-balancing and heat-sensitive moxibustion groups(P<0.05).Compared with the baseline,the VAS and WOMAC scores and the serum levels of CTX-Ⅰ,TRACP-5b,ADAMTS-4,and MMP-3 decreased significantly in all three groups after treatment and at the 2-week and 6-week follow-ups(P<0.05).At the same three time points,the VAS and WOMAC scores and serum levels of CTX-Ⅰ,TRACP-5b,ADAMTS-4,and MMP-3 were lower in the joint intervention group than in the knee-balancing and heat-sensitive moxibustion groups(P<0.001).Conclusion Either used alone or combined,the knee-balancing manipulation and heat-sensitive moxibustion therapy can improve the symptoms and down-regulate the serum levels of CTX-Ⅰ,TRACP-5b,ADAMTS-4,and MMP-3 in KOA patients,producing durable efficacy;nevertheless,a more significant efficacy can be achieved by combining the two methods.

Clinical observation of acupuncture combined with sitting-position knee-adjustment manipulations for patellofemoral arthritis

Objective To observe the efficacy of acupuncture combined with sitting-position knee-adjustment manipulations in treating patellofemoral osteoarthritis.Methods Ninety-two patients with patellofemoral osteoarthritis were randomized into an observation group and a medication group,with 46 cases in each group.The observation group received acupuncture and sitting-position knee-adjustment manipulations,and the medication group received oral celecoxib capsules.After 8-week treatment,changes in the short-form McGill pain questionnaire(SF-MPQ)and Lysholm knee scoring scale(LKSS)scores were observed,and the clinical efficacy was compared.Results The total effective rate was 87.0%in the observation group and 63.0%in the control group;the between-group difference was statistically significant.Before treatment,there were no significant differences in the SF-MPQ score or LKSS score(P>0.05).After 8-week treatment,the SF-MPQ[including pain rating index(PRI),visual analog scale(VAS),and present pain intensity(PPI)]and LKSS scores showed notable changes in both groups(P<0.05);the SF-MPQ and LKSS scores in the observation group were significantly different from those in the control group(P<0.05).Conclusion Combining acupuncture and sitting-position knee-adjustment manipulations can reduce pain and ameliorate joint function in patients with patellofemoral osteoarthritis,producing more significant efficacy than oral celecoxib capsules.

Research on clinical application of manual therapy to tumor-related adverse reactions

Objective To analyze the clinical application of manual therapy(MT)to tumor-related adverse reactions via summarizing the research at home and abroad,in order to provide more theoretical evidence for the clinical promotion of MT.Methods We searched 7 Chinese and English databases,including China National Knowledge Infrastructure(CNKI),Wanfang Academic Journal Full-text Database(Wanfang),Chongqing VIP Database(CQVIP),PubMed,Excerpta Medica Database(EMBASE),Ovid and EBSCO.The publication date was between the establishment date of the database and December 31,2020.We screened the literature according to the inclusion and exclusion criteria,and then sorted and analyzed the selected information.Results A total of 46 papers were analyzed.Most studies focused on the adverse reactions in breast cancer patients.MT interventions demonstrated the best efficacy for fatigue,followed by pain,depression and anxiety.In different MT interventions,Tuina(Chinese therapeutic massage)was mainly adopted for fatigue,pain,anxiety,depression,and limb dysfunctions.Acupoint pressing was mainly adopted for gastrointestinal and psychological problems such as abdominal bloating,insomnia,depression and anxiety.The application of reflexotherapy was similar to that of Tuina.Conclusion MT can alleviate various adverse reactions by effectively relieving patients’somatic symptoms and improving their psychological states and overall functions.It can be popularized as a significant non-drug therapy.Currently,however,the clinical application of MT is neither extensive nor has sufficient basic research.Consequently,we should attach importance to this application.

Effects of Tuina on serum creatine kinase and skeletal muscle mitochondria in delayed onset muscle soreness model rats

Objective To observe the effect of Tuina(Chinese therapeutic massage)on creatine kinase(CK),mitochondrial Ca^(2+)concentration,and ultrastructure of skeletal muscle in delayed onset muscle soreness(DOMS)model rats.Methods A total of 130 healthy male Sprague-Dawley rats were randomly divided into a blank group,an exercise control group,a pre-exercise Tuina group,and a post-exercise Tuina group.According to the time points for sample collection,the exercise control group was divided into a 0 h exercise control group,a 24 h exercise control group,a 48 h exercise control group,and a 72 h exercise control group;the pre-exercise Tuina group was further divided into a 0 h pre-exercise Tuina group,a 24 h pre-exercise Tuina group,a 48 h pre-exercise Tuina group,and a 72 h pre-exercise Tuina group;and the post-exercise Tuina group was divided into a 0 h post-exercise Tuina group,a 24 h post-exercise Tuina group,a 48 h post-exercise Tuina group,and a 72 h post-exercise Tuina group.Rats in all groups except for the blank group received DOMS modeling.Professionals performed Nie-Pinching manipulation and finger Nian-Twisting manipulation on the lower limbs of the rats.The samples were collected at 0 h,24 h,48 h,or 72 h after exhaustive exercise for each pre-exercise Tuina group.The samples were collected at 0 h,24 h,48 h,or 72 h after Tuina for each post-exercise Tuina group.The changes in serum CK,skeletal muscle mitochondrial Ca^(2+)concentration,and Ca^(2+)-adenosine triphosphatase(ATPase)were determined.The ultrastructure changes of skeletal muscles in each group were observed by a transmission electron microscope.Results The electron microscope showed that compared with the exercise control group,the skeletal muscle structures of the pre-exercise Tuina group and the post-exercise Tuina group were significantly improved,and the overall performance of skeletal muscle in the pre-exercise Tuina group was more similar to that of the blank group.The level of serum CK in the pre-exercise Tuina group and the post-exercise Tuina group was significantly lower than that in the exercise control group(P<0.01).The Ca^(2+)concentration of skeletal muscle in the 24 h,48 h,and 72 h pre-exercise Tuina groups was lower than that in the post-exercise Tuina group at the same time point(P<0.01).The Ca^(2+)-ATPase concentration of skeletal muscle in the 24 h and 72 h pre-exercise Tuina groups was lower than that in the post-exercise Tuina group at the same time point(P<0.05).Conclusion Tuina effectively prevents muscle damage caused by heavy exercise and long-term exercise,which may be related to the increase of skeletal muscle Ca^(2+)-ATPase activity and mitochondrial Ca^(2+)transport.

Observation of the efficacy and safety of the Song-Relaxing and Zhen-Vibrating abdomen manipulation for patients with prediabetes

Objective:To observe the safety of the Song-Relaxing and Zhen-Vibrating abdomen manipulation in treating patients with prediabetes and its effects on blood glucose and lipid metabolism.Methods:One hundred and two patients with prediabetes were divided into a manipulation group and a control group according to the random number table method,with 51 cases in each group.All patients received the general behavioral intervention for prediabetes,with additional Song-Relaxing and Zhen-Vibrating abdomen manipulation in the manipulation group and oral metformin hydrochloride tablets in the control group.Both groups received the intervention for six months.Results:Fourteen patients dropped out during the treatment,and a total of 88 patients completed the trial,including 45 cases in the manipulation group and 43 cases in the control group.After the treatment,the prediabetes control rate was 93.3%in the manipulation group and 74.4%in the control group,and the difference between the two groups was statistically significant(P<0.05);no patient in the manipulation group progressed to diabetes,while the rate of conversion to diabetes in the control group was 6.9%,with a significant difference between the two groups(P<0.05).After the treatment,the body mass index(BMI),glycosylated hemoglobin A1c(HbA1c),fasting plasma glucose(FPG),2-hour postload plasma glucose(2hPG)level during an oral glucose tolerance test(OGTT),fasting insulin(FINS),homeostasis model assessment-2 of insulin resistance(HOMA2-IR),total cholesterol(TC),and triglycerides(TG)decreased in both groups versus baseline,with significant differences within the groups;the levels of all indicators were lower in the manipulation group than in the control group(P<0.05),and the differences between the two groups were more prominent at the sixth month(P<0.01).At the sixth month,the high-density lipoprotein cholesterol(HDL-C)in the manipulation group was increased,while there was no significant change in the control group.In the control group,three patients reported mild gastrointestinal reactions at the initial dosing,which improved after medication adjustment.No other adverse events were observed in either group.Conclusion:Both metformin hydrochloride tablets and the Song-Relaxing and Zhen-Vibrating abdomen manipulation can improve blood glucose and lipid metabolism and reduce insulin resistance and clinical discomfort in patients with prediabetes,but the Song-Relaxing and Zhen-Vibrating abdomen manipulation has higher efficacy and safety.

Tuina plus Traction for Cervical Distortion in Teenagers:A Report of 40 Cases

Objective： To observe the clinical effect of tuina plus traction for cervical distortion in teenagers. Methods： Tuina plus traction was applied to 40 teenagers with cervical distortion once every other day, and 10 days make up 1 treatment course. The therapeutic effect was evaluated after 2 courses. Result： Significant changes occurred after the treatment： 15 cases got correction, 20 cases got substantial improvement and 5 cases got certain improvement. Conclusion： Tuina plus traction works effectively for abnormal cervical physiological curve in teenagers.