Although research on a field investigation about quantification drawdown of ground water wells has hitherto been conducted with emphasis on Sana'a basin which is 3 200 km2 in area characterized by general hazard i...Although research on a field investigation about quantification drawdown of ground water wells has hitherto been conducted with emphasis on Sana'a basin which is 3 200 km2 in area characterized by general hazard in quantity and quality of water,there exist uncertainties about the size of the hazardous annual decline in the level of underground water. So the authors are trying to assess reliable hazard data on the depth of ground-water which were obtained by measuring static water level. The data set are twenty six wells from 9 regions which were selected to represent Sana'a basin and collected during the course of the 20 months groundwater monitoring survey from January 2008 to January 2009. The results show that the average drawdown during 20 months to be 3.22 m with an average 0.16 m per month and 2 m per year.展开更多
A recent developed Cycloconverter-IM haulage drive for underground mining is described in this paper. The control of this system is fully digitized. Six INTEL 8031 single-chip microprocessors are interconnected to per...A recent developed Cycloconverter-IM haulage drive for underground mining is described in this paper. The control of this system is fully digitized. Six INTEL 8031 single-chip microprocessors are interconnected to perform the functions of motor speed control,cycloconverter firing , fault diagnosis,etc. The implementations of the above functions are illustrated,and also a new method called "slip feedback control" for improving power factor of cycloconverter is put forward in this paper.展开更多
Sini Power（SP） is a famed traditional Chinese formula that has long been used to treat depression. Here, we investigated the effects and possible mechanisms of SP extract on an established model of depression： chro...Sini Power（SP） is a famed traditional Chinese formula that has long been used to treat depression. Here, we investigated the effects and possible mechanisms of SP extract on an established model of depression： chronic stressed tree shrew, which mimics the human condition of social stress. The animals were divided into 4 groups. Except for the na？ve group, the other animals were subjected to daily social defeat stress for 5 weeks, and during the last 4 weeks treated with SP extract（3.6 g/kg/d）, fluoxetine（15 mg/kg/d）, and vehicle, respectively. The results showed that SP extract could reverse body weight loss to a certain extent and reduce the levels of urine/serum cortisol that were initially increased by chronic social defeat. In addition, SP extract increased hippocampus norepinephrine concentrations. Our data suggested that SP extract had positive effects on the main depression symptoms in the chronic stressed tree shrew model and that it may be used to help control hypothalamic-pituitary-adrenal axis hyperactivity.展开更多
Objective：To study the expression changes of matrix metal loproteinases （MMPs） in traumatic deep vein thrombosis （TDVT） in a rat model with the aid of gene chip technology and to explore the roles of MMPs in TDVT...Objective：To study the expression changes of matrix metal loproteinases （MMPs） in traumatic deep vein thrombosis （TDVT） in a rat model with the aid of gene chip technology and to explore the roles of MMPs in TDVT.Methods：Totally 150 Sprague Dawley rats were randomly divided into control group （n=10） and model group （n=140）. Rat models of TDVT were established by clamping the femoral vein and fixing the bilateral hind limbs. Then fixation of the hip spica with plaster bandage was conducted.According to the observation phases and/or biological situations of the femoral vein thrombosis, the model rats were further divided into 7 groups. Vascular tissues were obtained from each group through noninvasive incision into the femoral vein at corresponding time points. We adopted the Trizoi one-step method for total RNA extraction,Affymetrix RAT 230 2.0 array for detection of RNA expressions and fold change （FC） analysis for changes of differential expressions of MMPs in each group. The main outcome parameters measured included expressions of MMP-2,MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11,MMP- 12, MMP-13, MMP- 14, MMP- 16, MMP-23 and MMP-24. Gene array data of these MMPs were analyzed by the Affymetrix Microarray Analysis software （Version 5.0）.Results：FC analysis showed differential expressions of MMPs in each group during the course of TDVT. At the initial period of thrombosis, MMP-2, MMP-3, MMP-7,MMP-8, MMP-9, MMP- 10, MMP-11, and MMP-24 had significantly high expression, while MMP-12, MMP-13,MMP-14, MMP-16 and MMP-23 had relatively low expression. MMPs were all highly expressed at the peak time of thrombosis. In the process of thrombus resolution,MMP-2, MMP-10, MMP-16 and MMP-24 have relatively low expression, while MMP-12, MMP-13, MMP-14,MMP-16 and MMP-23 have significantly high expression.Conclusion：MMPs may affect the process of TDVT through transcription regulation of the fibrinolysis-anti-fibrinolytic system during the course of thrombosis and thrombus resolution.展开更多
文摘Although research on a field investigation about quantification drawdown of ground water wells has hitherto been conducted with emphasis on Sana'a basin which is 3 200 km2 in area characterized by general hazard in quantity and quality of water,there exist uncertainties about the size of the hazardous annual decline in the level of underground water. So the authors are trying to assess reliable hazard data on the depth of ground-water which were obtained by measuring static water level. The data set are twenty six wells from 9 regions which were selected to represent Sana'a basin and collected during the course of the 20 months groundwater monitoring survey from January 2008 to January 2009. The results show that the average drawdown during 20 months to be 3.22 m with an average 0.16 m per month and 2 m per year.
文摘A recent developed Cycloconverter-IM haulage drive for underground mining is described in this paper. The control of this system is fully digitized. Six INTEL 8031 single-chip microprocessors are interconnected to perform the functions of motor speed control,cycloconverter firing , fault diagnosis,etc. The implementations of the above functions are illustrated,and also a new method called "slip feedback control" for improving power factor of cycloconverter is put forward in this paper.
基金National Basic Research Program of China(Grant No.2011CB505100)funded by the Ministry of Science and Technology of China
文摘Sini Power（SP） is a famed traditional Chinese formula that has long been used to treat depression. Here, we investigated the effects and possible mechanisms of SP extract on an established model of depression： chronic stressed tree shrew, which mimics the human condition of social stress. The animals were divided into 4 groups. Except for the na？ve group, the other animals were subjected to daily social defeat stress for 5 weeks, and during the last 4 weeks treated with SP extract（3.6 g/kg/d）, fluoxetine（15 mg/kg/d）, and vehicle, respectively. The results showed that SP extract could reverse body weight loss to a certain extent and reduce the levels of urine/serum cortisol that were initially increased by chronic social defeat. In addition, SP extract increased hippocampus norepinephrine concentrations. Our data suggested that SP extract had positive effects on the main depression symptoms in the chronic stressed tree shrew model and that it may be used to help control hypothalamic-pituitary-adrenal axis hyperactivity.
文摘Objective：To study the expression changes of matrix metal loproteinases （MMPs） in traumatic deep vein thrombosis （TDVT） in a rat model with the aid of gene chip technology and to explore the roles of MMPs in TDVT.Methods：Totally 150 Sprague Dawley rats were randomly divided into control group （n=10） and model group （n=140）. Rat models of TDVT were established by clamping the femoral vein and fixing the bilateral hind limbs. Then fixation of the hip spica with plaster bandage was conducted.According to the observation phases and/or biological situations of the femoral vein thrombosis, the model rats were further divided into 7 groups. Vascular tissues were obtained from each group through noninvasive incision into the femoral vein at corresponding time points. We adopted the Trizoi one-step method for total RNA extraction,Affymetrix RAT 230 2.0 array for detection of RNA expressions and fold change （FC） analysis for changes of differential expressions of MMPs in each group. The main outcome parameters measured included expressions of MMP-2,MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11,MMP- 12, MMP-13, MMP- 14, MMP- 16, MMP-23 and MMP-24. Gene array data of these MMPs were analyzed by the Affymetrix Microarray Analysis software （Version 5.0）.Results：FC analysis showed differential expressions of MMPs in each group during the course of TDVT. At the initial period of thrombosis, MMP-2, MMP-3, MMP-7,MMP-8, MMP-9, MMP- 10, MMP-11, and MMP-24 had significantly high expression, while MMP-12, MMP-13,MMP-14, MMP-16 and MMP-23 had relatively low expression. MMPs were all highly expressed at the peak time of thrombosis. In the process of thrombus resolution,MMP-2, MMP-10, MMP-16 and MMP-24 have relatively low expression, while MMP-12, MMP-13, MMP-14,MMP-16 and MMP-23 have significantly high expression.Conclusion：MMPs may affect the process of TDVT through transcription regulation of the fibrinolysis-anti-fibrinolytic system during the course of thrombosis and thrombus resolution.
