AIM： To prospectively assess the changes in parameters of computed tomography （CT） perfusion pre- and post-transarterial chemoembolization （TACE） of hepatocellular carcinoma （HCC） in different treatment respons...AIM： To prospectively assess the changes in parameters of computed tomography （CT） perfusion pre- and post-transarterial chemoembolization （TACE） of hepatocellular carcinoma （HCC） in different treatment response groups, and to correlate the changes with various responses of HCC to TACE. METHODS： Thirty-nine HCC patients underwent CT perfusion examinations pre-（1 d before TACE） and post-treatment （4 wk after TACE）. The response evaluation criteria for solid tumors （RECIST） were referred to when treatment responses were distributed. Wilcoxon-signed ranks test was used to compare the differences in CT perfusion parameters pre- and post- TACE for different response groups. RESULTS： Only one case had treatment response to CR and the CT perfusion maps of post-treatment lesion displayed complete absence of signals. In the PR treatment response group, hepatic artery perfusion （HAP）, hepatic arterial fracture （HAF） and hepatic blood volume （HBV） of viable tumors post-TACE were reduced compared with pre-TACE （P = 0.001, 0.030 and 0.001, respectively）. In the SD group, all CT perfusion parameters were not significantly different pre- and post-TACE. In the PD group, HAP, HAl=, portal vein perfusion （PVP） and hepatic blood flow （HBF） of viable tumors post-TACE were significantly increased compared with pre-TACE （P = 0.005, 0.012, 0.035 and 0.005, respectively）. CONCLUSION： Changes in CT perfusion parameters of viable tumors are correlated with different responses of HCC to TACE. Therefore, CT perfusion imaging is a feasible technique for monitoring response of HCC to TACE.展开更多
This paper will present the characteristics of flow behavior and thermal field of both free and impingement jet issued from a circular orifice nozzle at Re=8900.The flow behavior of a single round jet and impingement ...This paper will present the characteristics of flow behavior and thermal field of both free and impingement jet issued from a circular orifice nozzle at Re=8900.The flow behavior of a single round jet and impingement jet was observed by smoke flow visualization recorded by a high speed camera using 5000 frame per second.Heat transfer coefficient on the impingement surface was measured by means of infrared camera (TVS-8500,Avio) with a two-dimensional array of Indeum-Antimony (In Sb) sensors varying in the separation distance between the nozzle and the target plate.The heat transfer coefficient changes in time and spatial.Therefore,the root mean square distribution of the heat transfer was obtained from the data.As a result,it was confirmed that the longitudinal vortex was observed outside of the ring vortex,and then the longitudinal vortex was penetrated in the jet flow.Moreover,the high value of root mean square of the heat transfer coefficient has spread radially in stripy manner,which is caused as the results of the longitudinal vortexes flowing in the radial direction on the impingement plate.展开更多
基金The Science Technology Program of Beijing Education Committee: KM200810025002
文摘AIM： To prospectively assess the changes in parameters of computed tomography （CT） perfusion pre- and post-transarterial chemoembolization （TACE） of hepatocellular carcinoma （HCC） in different treatment response groups, and to correlate the changes with various responses of HCC to TACE. METHODS： Thirty-nine HCC patients underwent CT perfusion examinations pre-（1 d before TACE） and post-treatment （4 wk after TACE）. The response evaluation criteria for solid tumors （RECIST） were referred to when treatment responses were distributed. Wilcoxon-signed ranks test was used to compare the differences in CT perfusion parameters pre- and post- TACE for different response groups. RESULTS： Only one case had treatment response to CR and the CT perfusion maps of post-treatment lesion displayed complete absence of signals. In the PR treatment response group, hepatic artery perfusion （HAP）, hepatic arterial fracture （HAF） and hepatic blood volume （HBV） of viable tumors post-TACE were reduced compared with pre-TACE （P = 0.001, 0.030 and 0.001, respectively）. In the SD group, all CT perfusion parameters were not significantly different pre- and post-TACE. In the PD group, HAP, HAl=, portal vein perfusion （PVP） and hepatic blood flow （HBF） of viable tumors post-TACE were significantly increased compared with pre-TACE （P = 0.005, 0.012, 0.035 and 0.005, respectively）. CONCLUSION： Changes in CT perfusion parameters of viable tumors are correlated with different responses of HCC to TACE. Therefore, CT perfusion imaging is a feasible technique for monitoring response of HCC to TACE.
文摘This paper will present the characteristics of flow behavior and thermal field of both free and impingement jet issued from a circular orifice nozzle at Re=8900.The flow behavior of a single round jet and impingement jet was observed by smoke flow visualization recorded by a high speed camera using 5000 frame per second.Heat transfer coefficient on the impingement surface was measured by means of infrared camera (TVS-8500,Avio) with a two-dimensional array of Indeum-Antimony (In Sb) sensors varying in the separation distance between the nozzle and the target plate.The heat transfer coefficient changes in time and spatial.Therefore,the root mean square distribution of the heat transfer was obtained from the data.As a result,it was confirmed that the longitudinal vortex was observed outside of the ring vortex,and then the longitudinal vortex was penetrated in the jet flow.Moreover,the high value of root mean square of the heat transfer coefficient has spread radially in stripy manner,which is caused as the results of the longitudinal vortexes flowing in the radial direction on the impingement plate.
