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从益气生脉摄脉探析糖尿病周围神经病变防治之理 被引量:3
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作者 张效科 袁有才 +2 位作者 邓翀 段玉红 王郁金 《四川中医》 2014年第12期26-28,共3页
本文以中医"益气生脉"、"益气摄脉"等有关"气血关系"为依据,从"脉络-血管系统"的同一性为出发点,较为系统的论述益气活血中药在防治糖尿病周围神经病变的作用及机理,重点阐述益气活血中药"... 本文以中医"益气生脉"、"益气摄脉"等有关"气血关系"为依据,从"脉络-血管系统"的同一性为出发点,较为系统的论述益气活血中药在防治糖尿病周围神经病变的作用及机理,重点阐述益气活血中药"益气生脉-血管新生"、"益气摄脉-血管神经屏障"等作用机理,为丰富和发展中医"益气生脉"、"益气摄脉"和"络病学说"等理论作出了有益的探索,并为中医药防治糖尿病神经血管病变提供方法学借鉴和科学依据。 展开更多
关键词 糖尿病 神经病变 益气生 摄脉
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0D-1D coupling model and 3D fluid-structure interaction model based on coronary CT angiography for displaying hemodynamic characteristics of coronary artery stenosis
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作者 LIU Shanfeng LU Xiaochen +1 位作者 TIAN Hao WU Huiqun 《中国医学影像技术》 CSCD 北大核心 2024年第8期1236-1241,共6页
Objective To observe value of 0D-1D coupling model and 3D fluid-structure interaction(FSI)model based on coronary CT angiography(CCTA)for displaying hemodynamic characteristics of coronary artery stenosis.Methods Base... Objective To observe value of 0D-1D coupling model and 3D fluid-structure interaction(FSI)model based on coronary CT angiography(CCTA)for displaying hemodynamic characteristics of coronary artery stenosis.Methods Based on CCTA data of the stenosed left anterior descending branch(LAD)in a patient with coronary heart disease,an 0D-1D coupling model and 3D FSI model were built,respectively.Then hemodynamic characteristic indexes,including the pressure,flow velocity and wall shear stress(WSS)were obtained in every 0.01 s during 1 s at 5 sampling points(i.e.sampling point 1—5)using these 2 models,respectively,and the consistencies of the results between models were evaluated with Spearman correlation coefficient r s.Results The time consuming for construction of 0D-1D coupling model and 3D FSI model was 0.033 min and 704 min,respectively.Both models showed basically distribution of the pressure,flow velocity and WSS of the stenosed LAD.For more details,the pressure at the stenosed segment of LAD and the proximal segment of stenosis were both higher,which gradually decreased at the distal segment of stenosis,and the flow velocity at the proximal segment of stenosis was in a relatively slow and uniform condition,with significantly increased flow velocity and WSS at the stenosed segment.Compared with 3D FSI model,0D-1D vascular coupling model was relatively unrefined and lack of distal flow lines when displaying blood flow velocity.For sampling point 2 at the stenosed segment of LAD,no significant consistency for pressure between 2 models was found(P=0.118),but strong consistency for the flow velocity and WSS(r s=0.730,0.807,both P<0.05).The consistencies of pressure,flow velocity and WSS between 2 models at the proximal and distal segment of stenosis,i.e.1,3—5 sampling points were week to moderate(r s=0.237—0.669,all P<0.05).Conclusion 0D-1D coupling model exhibited outstanding computational efficiency and might provide relatively reasonable results,while 3D FSI model showed higher accuracy for details and streamline when simulating LAD stenosis. 展开更多
关键词 coronary stenosis HEMODYNAMICS coronary angiography tomography X-ray computed
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Computed tomography perfusion in evaluating the therapeutic effect of transarterial chemoembolization for hepatocellular carcinoma 被引量:36
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作者 Guang Chen Da-Qing Ma Wen He Bao-Feng Zhang Li-Qin Zhao 《World Journal of Gastroenterology》 SCIE CAS CSCD 2008年第37期5738-5743,共6页
AIM: To prospectively assess the changes in parameters of computed tomography (CT) perfusion pre- and post-transarterial chemoembolization (TACE) of hepatocellular carcinoma (HCC) in different treatment respons... AIM: To prospectively assess the changes in parameters of computed tomography (CT) perfusion pre- and post-transarterial chemoembolization (TACE) of hepatocellular carcinoma (HCC) in different treatment response groups, and to correlate the changes with various responses of HCC to TACE. METHODS: Thirty-nine HCC patients underwent CT perfusion examinations pre-(1 d before TACE) and post-treatment (4 wk after TACE). The response evaluation criteria for solid tumors (RECIST) were referred to when treatment responses were distributed. Wilcoxon-signed ranks test was used to compare the differences in CT perfusion parameters pre- and post- TACE for different response groups. RESULTS: Only one case had treatment response to CR and the CT perfusion maps of post-treatment lesion displayed complete absence of signals. In the PR treatment response group, hepatic artery perfusion (HAP), hepatic arterial fracture (HAF) and hepatic blood volume (HBV) of viable tumors post-TACE were reduced compared with pre-TACE (P = 0.001, 0.030 and 0.001, respectively). In the SD group, all CT perfusion parameters were not significantly different pre- and post-TACE. In the PD group, HAP, HAl=, portal vein perfusion (PVP) and hepatic blood flow (HBF) of viable tumors post-TACE were significantly increased compared with pre-TACE (P = 0.005, 0.012, 0.035 and 0.005, respectively). CONCLUSION: Changes in CT perfusion parameters of viable tumors are correlated with different responses of HCC to TACE. Therefore, CT perfusion imaging is a feasible technique for monitoring response of HCC to TACE. 展开更多
关键词 Hepatocellular carcinoma Computed tomography Transarterial chemoembolization Digital subtraction arteriography Region of interest
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Spectral computed tomography in advanced gastric cancer: Can iodine concentration non-invasively assess angiogenesis? 被引量:57
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作者 Xiao-Hua Chen Ke Ren +3 位作者 Pan Liang Yaru Chai Kui-Sheng Chen Jian-Bo Gao 《World Journal of Gastroenterology》 SCIE CAS 2017年第9期1666-1675,共10页
AIM To investigate the correlation of iodine concentration(IC) generated by spectral computed tomography(CT) with micro-vessel density(MVD) and vascular endothelial growth factor(VEGF) expression in patients with adva... AIM To investigate the correlation of iodine concentration(IC) generated by spectral computed tomography(CT) with micro-vessel density(MVD) and vascular endothelial growth factor(VEGF) expression in patients with advanced gastric carcinoma(GC).METHODS Thirty-four advanced GC patients underwent abdominal enhanced CT in the gemstone spectral imaging mode. The IC of the primary lesion in the arterial phase(AP) and venous phase(VP) were measured, and were then normalized against that in the aorta to provide the normalized IC(nI C). MVD and VEGF were detected by immunohistochemical assays, using CD34 and VEGF-A antibodies, respectively. Correlations of nI C with MVD, VEGF, and clinical-pathological features were analyzed.RESULTS Both nI Cs correlated linearly with MVD and were higher in the primary lesion site than in the normal control site, but were not correlated with VEGF expression. After stratification by clinical-pathological subtypes, nI C-AP showed a statistically significant correlation with MVD, particularly in the group with tumors at stage T4, without nodular involvement, of a mixed Lauren type, where the tumor was located at the antrum site, and occurred in female individuals. nI C-VP showed a positive correlation with MVD in the group with the tumor at stage T4 and above, had nodular involvement, was poorly differentiated, was located at the pylorus site, of a mixed and diffused Lauren subtype, and occurred in male individuals. nI C-AP and nI C-VP showed significant differences in terms of histological differentiation and Lauren subtype.CONCLUSION The IC detected by spectral CT correlated with the MVD. n IC-AP and n IC-VP can reflect angiogenesis in different pathological subgroups of advanced GC. 展开更多
关键词 Micro-vessel density Iodine concentration Spectral computed tomography Vascular endothelial growth factor Gastric cancer
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Sixty-four-slice computed tomography in surgical strategy of portal vein cavernous transformation 被引量:9
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作者 Ming-Man Zhang Cong-Lun Pu Ying-Cun Li Chun-Bao Guo 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第38期4334-4338,共5页
AIM:To investigate the role of 64-slice computed tomography(CT) in portal vein cavernous transformation to determine surgical strategy.METHODS:The site of lesions and extent of collateral circulation in 12 pediatric c... AIM:To investigate the role of 64-slice computed tomography(CT) in portal vein cavernous transformation to determine surgical strategy.METHODS:The site of lesions and extent of collateral circulation in 12 pediatric cases of cavernous transformation of the portal vein with surgical treatment were analyzed.RESULTS:Eleven of 12 children had esophageal varices and were treated with lower esophageal and gastric devascularization and splenectomy,and the other case was only treated with splenectomy.There were eight cases with spontaneous spleen/stomach-renal shunt,four with Retzius vein opening,which was reserved during surgery.Three cases of lesions involving the intrahepatic portal vein(PV) were treated with living donor liver transplantation.One patient died from PV thrombosis after liver transplantation,and the rest had no significant complications.CONCLUSION:The PV,its branches and collateral circulation were clearly seen by 64-slice spiral CT angiography,which helped with preoperative surgical planning. 展开更多
关键词 Cavernous transformation Portal vein Co4-slicecomputed tomography Liver transplantation Portal hyper-tension Esophageal devascularization Gastric devascularization
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CORONARY ANGIOGRAPHY WITH DUAL SOURCE COMPUTED TOMOGRAPHY:INITIAL EXPERIENCE 被引量:4
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作者 Zhu-hua Zhang Zheng-yu Jin +12 位作者 Shu-yang Zhang Song-bai Lin Dong-jing Li Ling-yan Kong Yi-ning Wang Lan Song Yun Wang Wen-min Zhao Wen-bin Mou Li-ren Zhang Wen-ling Zhu Qi Miao Qi Fang 《Chinese Medical Sciences Journal》 CAS CSCD 2007年第4期205-210,共6页
Objective To explore the scan technique and image quality of coronary angiography with dual source computed tomography(CT) without oral metoprolol preparation.Methods Plain and enhanced dual source CT coronary angiogr... Objective To explore the scan technique and image quality of coronary angiography with dual source computed tomography(CT) without oral metoprolol preparation.Methods Plain and enhanced dual source CT coronary angiography without oral metoprolol preparation was prospectively performed in 600 patients.Calcium scoring with plain scan images as well as multi-planar reconstruction(MPR),maximum intensity projection(MIP),and volume rendering technique(VRT) reconstruction with enhanced scan images were performed in all cases.The scan technique and post-reconstruction experience was summarized.The image quality was classified as 1 to 4 points,and coronary segments classified according to the American Heart Association standards were evaluated.Results The average calcium score of the 600 cases was 213.6±298.7(0-3 216.5).The average heart rate of the enhanced scan was 82.1±16.2(47-139) bpm.The post-reconstruction methods with which coronary segments could be shown as best as possible consisted of single phase reconstruction method,two or more phases supplemented method,and electrocardiogram editing method.Altogether 8 457 coronary segments were evaluated,among which 97.2% were evaluated as point 1,1.7% point 2,0.5% point 3,and 0.6% point 4.The coronary segments in 261 cases were completely normal,while 360 segments were diagnosed with <50% stenosis and 625 segments with ≥50% stenosis.Conclusions Excellent coronary artery image can be obtained with dual source CT in patients with any heart rate without oral metoprolol preparation.Heart rate is not a major source of the artifact,coronary segments can be well shown with single or multiple-phase reconstruction method. 展开更多
关键词 computed tomography coronary angiography coronary heart disease
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Highly metabolic thrombus of the portal vein:^(18)F fluorodeoxyglucose positron emission tomography/computer tomography demonstration and clinical significance in hepatocellular carcinoma 被引量:7
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作者 Long Sun Yong-Song Guan +4 位作者 Wei-Ming Pan Gui-Bing Chen Zuo-Ming Luo Ji-Hong Wei Hua Wu 《World Journal of Gastroenterology》 SCIE CAS CSCD 2008年第8期1212-1217,共6页
AIM: To assess the ability of ^18F-fluorodeoxyglucose positron emission tomography/computer tomography (^18F-FDG PET/CT) to differentiate between benign and malignant portal vein thrombosis in hepatocellular carcin... AIM: To assess the ability of ^18F-fluorodeoxyglucose positron emission tomography/computer tomography (^18F-FDG PET/CT) to differentiate between benign and malignant portal vein thrombosis in hepatocellular carcinoma (HCC) patients.METHODS: Five consecutive patients who had HBV cirrhosis, biopsy-proven HCC, and thrombosis of the main portal vein and/or left/right portal vein on ultrasound (US), computer tomography (CT) or magnetic resonance imaging (MRI) were studied with ^18F-FDG PET/CT. The presence or absence of a highly metabolic thrombus on ^18F-FDG PET/CT was considered diagnostic for malignant or benign portal vein thrombosis, respectively. All patients were followed-up monthly with US, CT or MRI. Shrinkage of the thrombus or recanalization of the vessels on US, CT or MRI during follow-up was considered to be definitive evidence of the benign nature of the thrombosis, whereas enlargement of the thrombus, disruption of the vessel wall, and parenchymal infiltration over follow-up were considered to be consistent with malignancy. ^18SF-FDG PET/CT, and US, CT or MRI results were compared.RESULTS: Follow-up (1 to 10 mo) showed signs of malignant thrombosis in 4 of the 5 patients. US, CT or MRI produced a true-positive result for malignancy in 4 of the patients, and a false-positive result in 1. ^18F-FDG PET/CT showed a highly metabolic thrombus in 4 of the 5 patients. ^18F-FDG PET/CT achieved a true-positive result in all 4 of these patients, and a true-negative result in the other patient. No false-positive result was observed using ^18F-FDG PET/CT.CONCLUSION: ^18F-FDG PET/CT may be helpful in discriminating between benign and malignant portal vein thrombi. Patients may benefit from ^18F-FDG PET/CT when portal vein thrombi can not be diagnosed exactly by US, CT or MRI. 展开更多
关键词 ^ 18F-fluorodeoxyglucose Positron emission tomography/computer tomography Hepatocellular carcinoma Portal vein tumor thrombus Portal vein blood thrombus
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Double aortic arch and nasogastric tubes: A fatal combination
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作者 Julia Massaad Kelly Crawford 《World Journal of Gastroenterology》 SCIE CAS CSCD 2008年第16期2590-2592,共3页
Double aortic arch is a common form of complete vascular ring that encircles both the trachea and the esophagus, and presents with various respiratory and esophageal symptoms, usually in the pediatric population. We p... Double aortic arch is a common form of complete vascular ring that encircles both the trachea and the esophagus, and presents with various respiratory and esophageal symptoms, usually in the pediatric population. We present a case of double aortic arch in an adult patient that manifested as massive upper gastrointestinal bleeding after prolonged nasogastric intubation. 展开更多
关键词 Nasogastric tubes Aortoesophageal fistula Gastrointestinal bleeding Double aortic arch Vasculardngs
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Design of ERT system 被引量:1
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作者 朱建平 王保良 +1 位作者 黄志尧 李海青 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 SCIE EI CAS CSCD 2005年第12期1446-1448,共3页
A new electrical resistance tomography (ERT) system, based on the bi-directional current pulse technique, is de- veloped. Polarization effects at the electrodes are eliminated. During each half cycle of the excitation... A new electrical resistance tomography (ERT) system, based on the bi-directional current pulse technique, is de- veloped. Polarization effects at the electrodes are eliminated. During each half cycle of the excitation process, direct current (DC) is used as the excitation source and filtering is not needed. Moreover, using optimized data collection protocol, the number of current injections for a 16-electrode system is reduced to 14 for 104 independent readings of an image. Experimental results showed that the system is effective using the sensitivity coefficient algorithm for image reconstruction. 展开更多
关键词 Electrical resistance tomography (ERT) Direct current (DC) EXCITATION RECONSTRUCTION
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张锡纯论治妇科杂病学术思想探析
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作者 钱虹 《云南中医中药杂志》 2017年第11期102-103,共2页
近代名医张锡纯在《医学表中参西录》中对妇科杂病之论治,首重冲脉之调摄,恒以调摄冲脉为首务,深究治法,精研方药;论证用药,颇具特色;方论之后,必附验案,以供后学师法。其重视冲脉,调摄冲脉论治妇科杂病的学术思想和临证经验,值得借鉴,... 近代名医张锡纯在《医学表中参西录》中对妇科杂病之论治,首重冲脉之调摄,恒以调摄冲脉为首务,深究治法,精研方药;论证用药,颇具特色;方论之后,必附验案,以供后学师法。其重视冲脉,调摄冲脉论治妇科杂病的学术思想和临证经验,值得借鉴,对于后学临证,颇具指导意义。 展开更多
关键词 张锡纯 《医学表中参西录》 论治妇科杂病
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Segmental radiofrequency ablation of pulmonary vein ostia for patients with refractory paroxysmal atrial fibrillation using multi-slice spiral computed tomography guidance 被引量:6
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作者 JIANG Chen-yang(蒋晨阳) +7 位作者 WANG Jian-an(王建安) HE Hong(何红) SUN Yong(孙勇) ZHOU Bin-quan(周斌全) 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2005年第12期1153-1156,共4页
Objective: To evaluate the safety and clinical efficacy of segmental radiofrequency ablation of pulmonary vein (PV) ostia for patients with refractory paroxysmal atrial fibrillation (AF) under multi-slice spiral ... Objective: To evaluate the safety and clinical efficacy of segmental radiofrequency ablation of pulmonary vein (PV) ostia for patients with refractory paroxysmal atrial fibrillation (AF) under multi-slice spiral computed tomography (MSCT) guidance before the procedure. Methods: A series of 58 consecutive patients with refractory paroxysmal AF were enrolled to undergo segmental radiofrequency ablation ofPV ostia. The 36 male and 22 female patients with mean age of (57.4±9.5) (32-79) years and no obvious organic heart disease. Before ablation, patients received MSCT to generate 3-dimentional image of the left atrium (LA) and proximal PVs. Patients then underwent segmental radiofrequency ablation ofPV ostia using PV circular mapping catheter manipulated several times to ensure complete isolation between PVs and LA. Results: No complications occurred during the procedure. One patient developed delayed cardiac tamponade, which was drained percutaneously. The mean follow-up time was (17.1±9.3) months. Forty-one patients (95%) experienced improved quality of life one month after the procedure. Thirty-six patients (83%) showed stable sinus rhythm, while 10 patients (23%) required additional anti-arrhythmic drugs. AF returned≥1 time in 6 (14%) patients who underwent anti-arrhythmic drug therapy, but the number of episodes was less than that before the procedure. However, one patient experienced recurrent episodes of atrial flutter. Conclusion: It is safe and effective to perform segmental radiofrequency ablation of PV ostia for patients with refractory paroxysmal AF using MSCT guidance mappening. 展开更多
关键词 Atrial fibrillation Pulmonary vein Radiofrequency ablation Multi-slice spiral computed tomography
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Pulsed digital holography for recording ultra-fast events
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作者 ZHAI Hong-chen WANG Xiao-lei +1 位作者 WANG Yi MU Guo-guang 《Optoelectronics Letters》 EI 2005年第1期72-74,共3页
In this paper,spatially angular multiplexing technique in pulsed digital holography and an optical system based on this technique are introduced.Optical simulation and calculating analysis show that the designed syste... In this paper,spatially angular multiplexing technique in pulsed digital holography and an optical system based on this technique are introduced.Optical simulation and calculating analysis show that the designed system can be employed to record ultra-fast events of a time resolution in nanosecond. 展开更多
关键词 空间多路技术 冲调制 全息 光学模拟
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Detecting Singularities with Harmonic Wavelets
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作者 CATTANI Carlo 杨建国 《Journal of Donghua University(English Edition)》 EI CAS 2009年第5期544-548,共5页
A simple method,based on harmonic wavelet analysis is proposed for the decomposition of a given energy bounded signal into a periodic signal and a pulse.Alike a denoising method,the first part signal it might represen... A simple method,based on harmonic wavelet analysis is proposed for the decomposition of a given energy bounded signal into a periodic signal and a pulse.Alike a denoising method,the first part signal it might represent a smooth periodic function while the pulse is a singular unpredicted perturbation (taken as a fault).It will be shown that,under some general conditions,by a simple projection into two disjoint space of functions we can easily separate the periodic component of the signal from the fault (represented by the singular pulse). 展开更多
关键词 WAVELETS SIGNAL noise Fourier series
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An Experimental Study on the Motion of Droplets in Flue Gas Humidification Activator with Pulse Laser Sheet Photography
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作者 Ke Jiang Xuchang Xu Xuegui Shi(State Key Laboratory of Efficient and Clean Combustion of Coal, Department of Thermal Engineering,Tsinghua University, Beijing 100084, China) 《Journal of Thermal Science》 SCIE EI CAS CSCD 1994年第2期142-146,共5页
In this paper a technique is introduced on visualization of emulsified droplets in gas stream by pulse laser sheet photography. By this technique fairly clear photographs of the concentration and velocity profiles of ... In this paper a technique is introduced on visualization of emulsified droplets in gas stream by pulse laser sheet photography. By this technique fairly clear photographs of the concentration and velocity profiles of water droplets in an activation reactor were obtained. The results of the study show that with a venturi tube installed in the activator, the distribution of the droplets is more uniform than without it; the uniformity of the distribution of the droplets can improve the efficiency of the activation of the sorbent particles in the reactor. The picture of the collision of the droplets was obtained in the experiment, which could be used as basis for the study of the mechanism of humidified activation process. The results of the experimental study of the deposition of the droplets on the reactor walls is also described and discussed. 展开更多
关键词 HUMIDIFIER ACTIVATOR pulse laser sheet photography distribution of droplets deposition.
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