AIM To investigate the prognostic value of preoperative fbri-nogen concentration （FIB） and D-dimer-fibrinogen ratio （DFR） in gastrointestinal stromal tumors （GISTs）.METHODS The purpose of this study was to retro...AIM To investigate the prognostic value of preoperative fbri-nogen concentration （FIB） and D-dimer-fibrinogen ratio （DFR） in gastrointestinal stromal tumors （GISTs）.METHODS The purpose of this study was to retrospectively ana-lyze 170 patients with GISTs who were admitted to our hospital from January 2010 to December 2015. The op-timal cutoff values of related parameters were estimated by receiver operating characteristic （ROC） curve analysis. The recurrence free survival （RFS） rate was evaluated using Kaplan-Meier curves. Univariate analysis and multivariate Cox regression models were used to analyze the prognostic factors of GISTs. The relationship between the FIB, D-dimer, DFR, platelet count （PLT）, and the clinicopathological features of GISTs was described by the chi-square test or nonparametric rank sum test （Mann-Whitney test）.RESULTS In ROC analysis, the optimal cutoff values of FIB, D-dimer, DFR, and PLT were 3.24 g/L, 1.24 mg/L, 0.354, and 197.5 （× 109/L）, respectively. Univariate analysis and the Kaplan-Meier survival curve showed that FIB, D-dimer, DFR, PLT,National Institutes of Health （NIH） risk category, tumor size, tumor location, and mitotic index were signifcantly relevant to the 3-year and 5-year survival rate of patients （ P 〈 0.05）. Cox multivariate regression analysis illustrated that FIB （RR： 0.108, 95%CI： 0.031-0.373）, DFR （RR： 0.319, 95%CI： 0.131-0.777）, and NIH risk category （ RR： 0.166, 95%CI： 0.047-0.589） were independent prognostic factors of the RFS rate （ P 〈 0. 05）. Moreover, FIB, D-dimer, DFR, and PLT were correlated with the clinical features of GISTs.CONCLUSIONFIB, D-dimer, DFR, and PLT are all related to the prognosis of GISTs. Moreover, FIB and DFR may be independent risk factors for predicting the prognosis of resectable GISTs.展开更多
This paper generally analyzes the current international and domestic brand evaluation theory on brand value. Starting from the most basic assessment of object analysis, it analyzes the current methods of brand evaluat...This paper generally analyzes the current international and domestic brand evaluation theory on brand value. Starting from the most basic assessment of object analysis, it analyzes the current methods of brand evaluation and its focus, and then analyzes the actual operation of the most authoritative international brand evaluation agencies - Interbrand, to conduct a detailed research and analysis. Based on this, combining with the current situation of China fashion brand market, it re-summaries the evaluation parameter respectively, from the short-term brand strength factors, to the long-term brand benefit and consumer factors, in order to establish a new evaluation frame fit for China fashion industry.展开更多
We study the initial value problem of the Davey-Stewartson systems for the elliptic-elliptic and hyperbolic-elliptic cases. The local and global existence and uniqueness of solutions in Hs is shown. Also, we prove tha...We study the initial value problem of the Davey-Stewartson systems for the elliptic-elliptic and hyperbolic-elliptic cases. The local and global existence and uniqueness of solutions in Hs is shown. Also, we prove that the scattering operator carries a band in Hs into Hs.展开更多
文摘AIM To investigate the prognostic value of preoperative fbri-nogen concentration （FIB） and D-dimer-fibrinogen ratio （DFR） in gastrointestinal stromal tumors （GISTs）.METHODS The purpose of this study was to retrospectively ana-lyze 170 patients with GISTs who were admitted to our hospital from January 2010 to December 2015. The op-timal cutoff values of related parameters were estimated by receiver operating characteristic （ROC） curve analysis. The recurrence free survival （RFS） rate was evaluated using Kaplan-Meier curves. Univariate analysis and multivariate Cox regression models were used to analyze the prognostic factors of GISTs. The relationship between the FIB, D-dimer, DFR, platelet count （PLT）, and the clinicopathological features of GISTs was described by the chi-square test or nonparametric rank sum test （Mann-Whitney test）.RESULTS In ROC analysis, the optimal cutoff values of FIB, D-dimer, DFR, and PLT were 3.24 g/L, 1.24 mg/L, 0.354, and 197.5 （× 109/L）, respectively. Univariate analysis and the Kaplan-Meier survival curve showed that FIB, D-dimer, DFR, PLT,National Institutes of Health （NIH） risk category, tumor size, tumor location, and mitotic index were signifcantly relevant to the 3-year and 5-year survival rate of patients （ P 〈 0.05）. Cox multivariate regression analysis illustrated that FIB （RR： 0.108, 95%CI： 0.031-0.373）, DFR （RR： 0.319, 95%CI： 0.131-0.777）, and NIH risk category （ RR： 0.166, 95%CI： 0.047-0.589） were independent prognostic factors of the RFS rate （ P 〈 0. 05）. Moreover, FIB, D-dimer, DFR, and PLT were correlated with the clinical features of GISTs.CONCLUSIONFIB, D-dimer, DFR, and PLT are all related to the prognosis of GISTs. Moreover, FIB and DFR may be independent risk factors for predicting the prognosis of resectable GISTs.
文摘This paper generally analyzes the current international and domestic brand evaluation theory on brand value. Starting from the most basic assessment of object analysis, it analyzes the current methods of brand evaluation and its focus, and then analyzes the actual operation of the most authoritative international brand evaluation agencies - Interbrand, to conduct a detailed research and analysis. Based on this, combining with the current situation of China fashion brand market, it re-summaries the evaluation parameter respectively, from the short-term brand strength factors, to the long-term brand benefit and consumer factors, in order to establish a new evaluation frame fit for China fashion industry.
基金the National Natural Science Foundation of China (Grant Nos. 19901007 and 19871020).
文摘We study the initial value problem of the Davey-Stewartson systems for the elliptic-elliptic and hyperbolic-elliptic cases. The local and global existence and uniqueness of solutions in Hs is shown. Also, we prove that the scattering operator carries a band in Hs into Hs.
