To adapt to the change in the demand of the oil refining market,two hydrocracking catalysts,RHC-1 and RHC-5,were developed to improve the quality of tail oil.The catalysts were designed based on the theory of selectiv...To adapt to the change in the demand of the oil refining market,two hydrocracking catalysts,RHC-1 and RHC-5,were developed to improve the quality of tail oil.The catalysts were designed based on the theory of selective ring-opening.By selecting more acidic molecular sieves,the problem of poor selectivity of conventional materials can be solved to properly match up to the hydrogenation performance of catalysts.Compared with the performance of previous catalysts,the quality of the tail oil achieved by the said catalysts is better,and the BMCI is reduced by 1—2 units.In the long cycle operation of the petroleum industry,the good quality of the tail oil has been verified and the adaptability of the process conditions is good.When the RHC-1 catalyst is used to process heavy feed under medium pressure,a BMCI value of about12 can be obtained along with a nearly 60%yield of tail oil.The total yield of chemical raw material(steaming cracking feed+catalytic reforming feed)can exceed 80%,and the hydrogen consumption has dropped by nearly 50%as compared to the conventional hydrocracking conversion rate.When processing a mixed CGO and VGO feed with the full conversion mode under a hydrogen pressure of 13.0 MPa,the RHC-5 catalyst can yield about 68.4%of heavy naphtha with a potential aromatic content of up to 50.6,while the total yield of chemical raw materials can reach more than 98%.The results of industrial application of these catalysts show that more than 30%of high quality tail oil can be obtained via processing of inferior quality feed,and its BMCI value can reach 10.7.The total yield of chemical raw materials can reach more than65%.The industrial operation process has implemented two operating cycles totaling 8 years.展开更多
A major natural hazard associated with LGOM （Legnica-Glogow Copper Mining） mining is the dynamic phenomena occurrence, physically observed as seismic tremors. Some of them generate effects in the form of relaxations...A major natural hazard associated with LGOM （Legnica-Glogow Copper Mining） mining is the dynamic phenomena occurrence, physically observed as seismic tremors. Some of them generate effects in the form of relaxations or bumps. Long-term observations of the rock mass behaviour indicate that the degree of seismic hazard, and therefore also seismic activity in the LGOM area, is affected by the great depth of the copper deposit, high-strength rocks as well as the ability of rock mass to accumulate elastic energy. In this aspect, the effect of the characteristics of initial stress tensor and the orientation of considered mining panel in regards to its components must be emphasised. The primary objective of this study is to answer the question, which of the factors considered as ＂influencing＂ the dynamic phenomena occurrence in copper mines have a statistically significant effect on seismic activity and to what extent. Using the general linear model procedure, an attempt has been made to quantify the impact of different parameters, including the depth of deposit, the presence of goaf in the vicinity of operating mining panels and the direction of mining face advance, on seismic activity based on historical data from 2000 to 2010 concerned with the dynamic phenomena recorded in different mining panels in Rudna mine. The direction of mining face advance as well as the goaf situation in the vicinity of the mining panel are of the greatest interest in the case of the seismic activity in LGOM. It can be assumed that the appropriate manipulation of parameters of mining systems should ensure the safest variant of mining method under specific geological and mining conditions.展开更多
5-Aminolevulinic acid （ALA） is a common precursor for tetrapyrrole compounds in all kinds of organ isms and has wide applications in agriculture and medicines. In this study, a new strategy, i.e. short-term dissolve...5-Aminolevulinic acid （ALA） is a common precursor for tetrapyrrole compounds in all kinds of organ isms and has wide applications in agriculture and medicines. In this study, a new strategy, i.e. short-term dissolved oxygen （DO） shock during aerobic fermentation, was introduced to produce 5-aminolevulinic acid with a recombi-nant E. coli. Effects of duration time of DO shock operation on plasmid concentration, intracellular ALA synthase （ALAS） activity and ALA production were investigated in Erlenmeyer shake flasks. The results indicated that both ALAS activity and ALA yield were enhanced in an anaerobic operation of 45 rain in the early exponential phase during fermentation, while they decreased when the anaerobic operation time was further increased to 60 rain. The DO shock protocol was confirmed with the fed-batch fermentation in a 15 L fermenter and the ALA production achieved 9.4 g.L-1 （72 mmol.L-1）, which is the highest yield in the fermentation broth reported up to now.展开更多
An accurate one-dimensional, heterogeneous model taking account of axial dispersion and heat transfer to the reactor wall, and heat conduction through the reactor wall for methanol synthesis in a bench scale reactor u...An accurate one-dimensional, heterogeneous model taking account of axial dispersion and heat transfer to the reactor wall, and heat conduction through the reactor wall for methanol synthesis in a bench scale reactor under periodic reversal of flow direction is presented. Adjustable parameters in this model are the effectiveness factors for each of the three reactions occurring in the synthesis and a factor for the bed to wall heat transfer coefficient correlation. Experimental data were used to evaluate these parameters and reasonable values of these parameters were obtained. The model was found to closely predict the reactor performance under a wide range of operating conditions, such as carbon oxide concentrations, volumetric flow rate, and cyclic period.展开更多
For its complexity, engineering construction schedule design is limited by various factors.Simulation-based engineering construction schedule takes critical path method (CPM) network as frame and calls complex cyclic ...For its complexity, engineering construction schedule design is limited by various factors.Simulation-based engineering construction schedule takes critical path method (CPM) network as frame and calls complex cyclic operation network (CYCLONE) simulation model enclosed in advance for its simulation nodes. CYCLONE simulation model takes charge of simulating stochastic duration of activity and efficiency of resources, while CPM model performs project scheduling. This combination avoids the shortcomings of both models. Furthermore, geographic information system (GIS) technique is utilized to visualize the construction processes which are otherwise difficult to be understood by static results described. Application in practical project verifies the feasibility and advantage of the technique.展开更多
Epithelial ovarian cancer is primarily a disease of older women. Advanced age is risk factor for decreased survival. Optimal surgery and the safe and effective administration of chemotherapy are essential for prolonge...Epithelial ovarian cancer is primarily a disease of older women. Advanced age is risk factor for decreased survival. Optimal surgery and the safe and effective administration of chemotherapy are essential for prolonged progression-free and overall survival(OS). In this article, the available regimens in both the primary treatment and relapsed setting are reviewed.展开更多
基金the financial support from the SINOPEC(No.114016)
文摘To adapt to the change in the demand of the oil refining market,two hydrocracking catalysts,RHC-1 and RHC-5,were developed to improve the quality of tail oil.The catalysts were designed based on the theory of selective ring-opening.By selecting more acidic molecular sieves,the problem of poor selectivity of conventional materials can be solved to properly match up to the hydrogenation performance of catalysts.Compared with the performance of previous catalysts,the quality of the tail oil achieved by the said catalysts is better,and the BMCI is reduced by 1—2 units.In the long cycle operation of the petroleum industry,the good quality of the tail oil has been verified and the adaptability of the process conditions is good.When the RHC-1 catalyst is used to process heavy feed under medium pressure,a BMCI value of about12 can be obtained along with a nearly 60%yield of tail oil.The total yield of chemical raw material(steaming cracking feed+catalytic reforming feed)can exceed 80%,and the hydrogen consumption has dropped by nearly 50%as compared to the conventional hydrocracking conversion rate.When processing a mixed CGO and VGO feed with the full conversion mode under a hydrogen pressure of 13.0 MPa,the RHC-5 catalyst can yield about 68.4%of heavy naphtha with a potential aromatic content of up to 50.6,while the total yield of chemical raw materials can reach more than 98%.The results of industrial application of these catalysts show that more than 30%of high quality tail oil can be obtained via processing of inferior quality feed,and its BMCI value can reach 10.7.The total yield of chemical raw materials can reach more than65%.The industrial operation process has implemented two operating cycles totaling 8 years.
文摘A major natural hazard associated with LGOM （Legnica-Glogow Copper Mining） mining is the dynamic phenomena occurrence, physically observed as seismic tremors. Some of them generate effects in the form of relaxations or bumps. Long-term observations of the rock mass behaviour indicate that the degree of seismic hazard, and therefore also seismic activity in the LGOM area, is affected by the great depth of the copper deposit, high-strength rocks as well as the ability of rock mass to accumulate elastic energy. In this aspect, the effect of the characteristics of initial stress tensor and the orientation of considered mining panel in regards to its components must be emphasised. The primary objective of this study is to answer the question, which of the factors considered as ＂influencing＂ the dynamic phenomena occurrence in copper mines have a statistically significant effect on seismic activity and to what extent. Using the general linear model procedure, an attempt has been made to quantify the impact of different parameters, including the depth of deposit, the presence of goaf in the vicinity of operating mining panels and the direction of mining face advance, on seismic activity based on historical data from 2000 to 2010 concerned with the dynamic phenomena recorded in different mining panels in Rudna mine. The direction of mining face advance as well as the goaf situation in the vicinity of the mining panel are of the greatest interest in the case of the seismic activity in LGOM. It can be assumed that the appropriate manipulation of parameters of mining systems should ensure the safest variant of mining method under specific geological and mining conditions.
基金Supported by the National Natural Science Foundation of China （20306026 and 20876141） and the National Basic Research program of China （2007CB707805）.
文摘5-Aminolevulinic acid （ALA） is a common precursor for tetrapyrrole compounds in all kinds of organ isms and has wide applications in agriculture and medicines. In this study, a new strategy, i.e. short-term dissolved oxygen （DO） shock during aerobic fermentation, was introduced to produce 5-aminolevulinic acid with a recombi-nant E. coli. Effects of duration time of DO shock operation on plasmid concentration, intracellular ALA synthase （ALAS） activity and ALA production were investigated in Erlenmeyer shake flasks. The results indicated that both ALAS activity and ALA yield were enhanced in an anaerobic operation of 45 rain in the early exponential phase during fermentation, while they decreased when the anaerobic operation time was further increased to 60 rain. The DO shock protocol was confirmed with the fed-batch fermentation in a 15 L fermenter and the ALA production achieved 9.4 g.L-1 （72 mmol.L-1）, which is the highest yield in the fermentation broth reported up to now.
基金The authors are grateful for financial support from the National Natural Science Foundation of China (No. 29476223) and the Ministry of Chemical Industry of China (No. 95-23-01).
文摘An accurate one-dimensional, heterogeneous model taking account of axial dispersion and heat transfer to the reactor wall, and heat conduction through the reactor wall for methanol synthesis in a bench scale reactor under periodic reversal of flow direction is presented. Adjustable parameters in this model are the effectiveness factors for each of the three reactions occurring in the synthesis and a factor for the bed to wall heat transfer coefficient correlation. Experimental data were used to evaluate these parameters and reasonable values of these parameters were obtained. The model was found to closely predict the reactor performance under a wide range of operating conditions, such as carbon oxide concentrations, volumetric flow rate, and cyclic period.
基金Supported by National Natural Science Foundation of China( No. 50179023).
文摘For its complexity, engineering construction schedule design is limited by various factors.Simulation-based engineering construction schedule takes critical path method (CPM) network as frame and calls complex cyclic operation network (CYCLONE) simulation model enclosed in advance for its simulation nodes. CYCLONE simulation model takes charge of simulating stochastic duration of activity and efficiency of resources, while CPM model performs project scheduling. This combination avoids the shortcomings of both models. Furthermore, geographic information system (GIS) technique is utilized to visualize the construction processes which are otherwise difficult to be understood by static results described. Application in practical project verifies the feasibility and advantage of the technique.
文摘Epithelial ovarian cancer is primarily a disease of older women. Advanced age is risk factor for decreased survival. Optimal surgery and the safe and effective administration of chemotherapy are essential for prolonged progression-free and overall survival(OS). In this article, the available regimens in both the primary treatment and relapsed setting are reviewed.
