既往研究表明,缺血病变体积可能是预测缺血性卒中功能转归的有用替代指标,但应结合病变部位加以考虑。以往使用的感兴趣区域(region of interest, ROI)方法存在若干缺点。因此,荷兰特文特大学诊断和介入神经放射学系的Ernst等进行了一...既往研究表明,缺血病变体积可能是预测缺血性卒中功能转归的有用替代指标,但应结合病变部位加以考虑。以往使用的感兴趣区域(region of interest, ROI)方法存在若干缺点。因此,荷兰特文特大学诊断和介入神经放射学系的Ernst等进行了一项研究,旨在使用更精确的体素方法来测量缺血病变部位对功能转归的影响。他们使用了来自荷兰急性缺血性卒中血管内治疗多中心随机临床试验(Multicenter Randomized Clinical Trial of Endovascular Therapy for Acute Ischemic Stroke in the Netherlands, MR CLEAN)的急性缺血性卒中患者数据集。主要终点是通过卒中后3个月改良Rankin量表评估的功能转归。展开更多
目前缺血性脑卒中常用量表广泛应用于临床及科研中,了解和使用这些量表成为现在神经科医生不可缺少的工作内容。本文主要介绍目前临床常用的脑卒中相关量表,包括ABCD2评分、美国国立卫生研究院卒中量表(national institute of health st...目前缺血性脑卒中常用量表广泛应用于临床及科研中,了解和使用这些量表成为现在神经科医生不可缺少的工作内容。本文主要介绍目前临床常用的脑卒中相关量表,包括ABCD2评分、美国国立卫生研究院卒中量表(national institute of health stroke scale,NIHSS)、Rankin修订量表(mRS)和Barthel指数量表及其他卒中相关量表。展开更多
目的:评估SF-36量表用于国人脊髓型颈椎病(cervical spondylotic myelopathy,CSM)患者健康相关生活质量(quality of life,QOL)的信度,并验证术后疗效评价中,生活质量评价与神经功能评估的一致性。方法:本研究前瞻性收集了接受手术治疗...目的:评估SF-36量表用于国人脊髓型颈椎病(cervical spondylotic myelopathy,CSM)患者健康相关生活质量(quality of life,QOL)的信度,并验证术后疗效评价中,生活质量评价与神经功能评估的一致性。方法:本研究前瞻性收集了接受手术治疗的脊髓型颈椎病患者142例,男84例,女58例,年龄60.0±10.9岁。所有患者均接受手术治疗。分别于术前、术后3个月、术后1年和术后2年以上末次随访时分别使用改良日本骨科协会评分法(modified Japanese Orthopaedic Association,mJOA)评分和健康状况调查简表(SF-36量表)进行神经功能和生活质量评估,并与正常人群的常模进行对比。使用克隆巴赫系数(Cronbachα)分析SF-36量表八个维度的信度,并进一步分析在术后不同随访时间节点SF-36各维度与神经功能评价的相关性。根据患者各项评分的变化趋势,分析患者的康复峰值时间。结果:术前CSM患者SF-36量表8个维度中,除“精神健康”维度外,其余7各维度较健康成年人常模均存在显著功能缺陷。SF-36量表各维度的Cronbachα介于0.73~0.85之间(Cronbachα:生理功能=0.85、生理职能=0.83、躯体疼痛=0.80、整体健康=0.81、活力=0.81、社会功能=0.79、情感职能=0.73、精神健康=0.75)。术后3个月时,mJOA评分的改善仅与患者SF-36量表中生理功能和躯体疼痛两个维度得分有显著相关性(相关系数R:生理功能=0.32,躯体疼痛=0.20;P<0.05);术后1年时,mJOA评分的改善与SF-36量表中生理功能、整体健康、社会功能和情感职能四个维度有显著相关性(相关系数R:生理功能=0.39,整体健康=0.24,社会功能=0.22,情感职能=0.19;P<0.05);在术后2年以上末次随访时,mJOA评分的改善与SF-36量表中生理功能、活力和情感职能三个维度显著相关(相关系数R:生理功能=0.38,活力=0.20,情感职能=0.20;P<0.05)。SF-36量表的生理总评分和心理总评分分别在17.7个月和18.9个月达到峰值。结论:SF-36量表各维度的信度较高,是一项可靠的评估CSM患者健康相关生活质量的方法。在术后不同随访期的疗效评估中,SF-36量表各维度与神经功能改善评估的一致性不尽相同:在术后恢复早期,mJOA评分的改善与SF-36量表中的生理相关维度显著相关;随着术后恢复期延长,mJOA评分的改善则与生理、心理相关维度均显著相关。展开更多
目的:探讨分析更年期女性共病糖尿病患者围绝经期症状现状及其生活质量,并分析其围绝经期症状特征。方法:本研究采用方便随机抽样法选取于2023年8月至2024年10月在吴起县人民医院妇产科、内科住院部或门诊部就诊的更年期女性共病糖尿病...目的:探讨分析更年期女性共病糖尿病患者围绝经期症状现状及其生活质量,并分析其围绝经期症状特征。方法:本研究采用方便随机抽样法选取于2023年8月至2024年10月在吴起县人民医院妇产科、内科住院部或门诊部就诊的更年期女性共病糖尿病患者作为调查对象,选用一般资料调查表、改良Kupperman评分量表、围绝经期生存质量量表(MENQOL)进行调查。本研究一般资料中计数资料用频数与构成比((n) %)来描述,计量资料符合正态分布采用(X¯±s)描述;组间比较采用t检验或方差分析,t检验或方差分析更年期女性共病糖尿病患者围绝经期相关症状在一般资料和疾病相关资料上的差异及影响因素,更年期女性共病糖尿病患者生命质量影响因素采用多元线性回归分析,以P P Objective: To investigate the status quo and quality of life of perimenopausal female patients with comorbidity diabetes, and to analyze the characteristics of perimenopausal symptoms. Method: In this study, convenient random sampling method was used to select menopausal female patients with comorbiditic diabetes who were treated in the obstetrics and gynecology department, internal medicine inpatient department or outpatient department of Wuqi County People’s Hospital from August 2023 to October 2024 as the investigation objects, and general data questionnaire, modified Kupperman score scale and Perimenopausal Quality of Life scale (MENQOL) were used Investigate. In the general data of this study, the counting data were described by frequency and component ratio ((n) %), and the measurement data conforming to normal distribution were described by (X¯±s). T test or analysis of variance were used for comparison between groups. T test or analysis of variance was used to analyze the differences and influencing factors of perimenopausal related symptoms in general data and disease-related data of menopausal female patients with comorbiditic diabetes, and there were statistical differences with P P < 0.05). Among the symptoms of perimenopausal syndrome, fatigue was the most common, followed by insomnia, irritability, depression and suspicion, vertigo, bone and joint pain, but in the symptoms of perimenopausal syndrome, urinary system infection, insomnia, sexual life symptoms accounted for a relatively large number of patients, accounting for 33.8%, 30.9%, 21.2% of the symptoms. Conclusion: In this study, the symptoms of perimenopausal syndrome were more serious and the quality of life was lower in menopausal women with comorbidities diabetes. The frequency and severity of perimenopausal syndrome increased with the increase of age, and the severity of perimenopausal syndrome also increased with the increase of disease course in female comorbidities. Fatigue is the most common symptom in this group, followed by insomnia, irritability, depression and suspicion, vertigo, osteoarthralgia side by side, but in the symptoms of perimenopausal syndrome, urinary system infection, insomnia, sexual life symptoms in severe patients accounted for a larger proportion, may be related to diabetic autonomic nervous dysfunction, the two symptoms superposition is the main factor affecting the quality of life in this group.展开更多
文摘既往研究表明,缺血病变体积可能是预测缺血性卒中功能转归的有用替代指标,但应结合病变部位加以考虑。以往使用的感兴趣区域(region of interest, ROI)方法存在若干缺点。因此,荷兰特文特大学诊断和介入神经放射学系的Ernst等进行了一项研究,旨在使用更精确的体素方法来测量缺血病变部位对功能转归的影响。他们使用了来自荷兰急性缺血性卒中血管内治疗多中心随机临床试验(Multicenter Randomized Clinical Trial of Endovascular Therapy for Acute Ischemic Stroke in the Netherlands, MR CLEAN)的急性缺血性卒中患者数据集。主要终点是通过卒中后3个月改良Rankin量表评估的功能转归。
文摘目前缺血性脑卒中常用量表广泛应用于临床及科研中,了解和使用这些量表成为现在神经科医生不可缺少的工作内容。本文主要介绍目前临床常用的脑卒中相关量表,包括ABCD2评分、美国国立卫生研究院卒中量表(national institute of health stroke scale,NIHSS)、Rankin修订量表(mRS)和Barthel指数量表及其他卒中相关量表。
文摘目的:评估SF-36量表用于国人脊髓型颈椎病(cervical spondylotic myelopathy,CSM)患者健康相关生活质量(quality of life,QOL)的信度,并验证术后疗效评价中,生活质量评价与神经功能评估的一致性。方法:本研究前瞻性收集了接受手术治疗的脊髓型颈椎病患者142例,男84例,女58例,年龄60.0±10.9岁。所有患者均接受手术治疗。分别于术前、术后3个月、术后1年和术后2年以上末次随访时分别使用改良日本骨科协会评分法(modified Japanese Orthopaedic Association,mJOA)评分和健康状况调查简表(SF-36量表)进行神经功能和生活质量评估,并与正常人群的常模进行对比。使用克隆巴赫系数(Cronbachα)分析SF-36量表八个维度的信度,并进一步分析在术后不同随访时间节点SF-36各维度与神经功能评价的相关性。根据患者各项评分的变化趋势,分析患者的康复峰值时间。结果:术前CSM患者SF-36量表8个维度中,除“精神健康”维度外,其余7各维度较健康成年人常模均存在显著功能缺陷。SF-36量表各维度的Cronbachα介于0.73~0.85之间(Cronbachα:生理功能=0.85、生理职能=0.83、躯体疼痛=0.80、整体健康=0.81、活力=0.81、社会功能=0.79、情感职能=0.73、精神健康=0.75)。术后3个月时,mJOA评分的改善仅与患者SF-36量表中生理功能和躯体疼痛两个维度得分有显著相关性(相关系数R:生理功能=0.32,躯体疼痛=0.20;P<0.05);术后1年时,mJOA评分的改善与SF-36量表中生理功能、整体健康、社会功能和情感职能四个维度有显著相关性(相关系数R:生理功能=0.39,整体健康=0.24,社会功能=0.22,情感职能=0.19;P<0.05);在术后2年以上末次随访时,mJOA评分的改善与SF-36量表中生理功能、活力和情感职能三个维度显著相关(相关系数R:生理功能=0.38,活力=0.20,情感职能=0.20;P<0.05)。SF-36量表的生理总评分和心理总评分分别在17.7个月和18.9个月达到峰值。结论:SF-36量表各维度的信度较高,是一项可靠的评估CSM患者健康相关生活质量的方法。在术后不同随访期的疗效评估中,SF-36量表各维度与神经功能改善评估的一致性不尽相同:在术后恢复早期,mJOA评分的改善与SF-36量表中的生理相关维度显著相关;随着术后恢复期延长,mJOA评分的改善则与生理、心理相关维度均显著相关。
文摘目的:探讨分析更年期女性共病糖尿病患者围绝经期症状现状及其生活质量,并分析其围绝经期症状特征。方法:本研究采用方便随机抽样法选取于2023年8月至2024年10月在吴起县人民医院妇产科、内科住院部或门诊部就诊的更年期女性共病糖尿病患者作为调查对象,选用一般资料调查表、改良Kupperman评分量表、围绝经期生存质量量表(MENQOL)进行调查。本研究一般资料中计数资料用频数与构成比((n) %)来描述,计量资料符合正态分布采用(X¯±s)描述;组间比较采用t检验或方差分析,t检验或方差分析更年期女性共病糖尿病患者围绝经期相关症状在一般资料和疾病相关资料上的差异及影响因素,更年期女性共病糖尿病患者生命质量影响因素采用多元线性回归分析,以P P Objective: To investigate the status quo and quality of life of perimenopausal female patients with comorbidity diabetes, and to analyze the characteristics of perimenopausal symptoms. Method: In this study, convenient random sampling method was used to select menopausal female patients with comorbiditic diabetes who were treated in the obstetrics and gynecology department, internal medicine inpatient department or outpatient department of Wuqi County People’s Hospital from August 2023 to October 2024 as the investigation objects, and general data questionnaire, modified Kupperman score scale and Perimenopausal Quality of Life scale (MENQOL) were used Investigate. In the general data of this study, the counting data were described by frequency and component ratio ((n) %), and the measurement data conforming to normal distribution were described by (X¯±s). T test or analysis of variance were used for comparison between groups. T test or analysis of variance was used to analyze the differences and influencing factors of perimenopausal related symptoms in general data and disease-related data of menopausal female patients with comorbiditic diabetes, and there were statistical differences with P P < 0.05). Among the symptoms of perimenopausal syndrome, fatigue was the most common, followed by insomnia, irritability, depression and suspicion, vertigo, bone and joint pain, but in the symptoms of perimenopausal syndrome, urinary system infection, insomnia, sexual life symptoms accounted for a relatively large number of patients, accounting for 33.8%, 30.9%, 21.2% of the symptoms. Conclusion: In this study, the symptoms of perimenopausal syndrome were more serious and the quality of life was lower in menopausal women with comorbidities diabetes. The frequency and severity of perimenopausal syndrome increased with the increase of age, and the severity of perimenopausal syndrome also increased with the increase of disease course in female comorbidities. Fatigue is the most common symptom in this group, followed by insomnia, irritability, depression and suspicion, vertigo, osteoarthralgia side by side, but in the symptoms of perimenopausal syndrome, urinary system infection, insomnia, sexual life symptoms in severe patients accounted for a larger proportion, may be related to diabetic autonomic nervous dysfunction, the two symptoms superposition is the main factor affecting the quality of life in this group.
