Molecular imaging(MI)can provide not only structural images using traditional imaging techniques but also functional and molecular information using many newly emerging imaging techniques.Over the past decade,the util...Molecular imaging(MI)can provide not only structural images using traditional imaging techniques but also functional and molecular information using many newly emerging imaging techniques.Over the past decade,the utilization of nanotechnology in MI has exhibited many significant advantages and provided new opportunities for the imaging of living subjects.It is expected that multimodality nanoparticles(NPs)can lead to precise assessment of tumor biology and the tumor microenvironment.This review addresses topics related to engineered NPs and summarizes the recent applications of these nanoconstructs in cancer optical imaging,ultrasound,photoacoustic imaging,magnetic resonance imaging(MRI),and radionuclide imaging.Key challenges involved in the translation of NPs to the clinic are discussed.展开更多
Objective: To investigate the role and clinical value of radionuclide imaging in hepatic impact injuries in rabbits. Methods: Rabbits were experimentally impacted on the liver with BIM IV bio impact machine. Liver ima...Objective: To investigate the role and clinical value of radionuclide imaging in hepatic impact injuries in rabbits. Methods: Rabbits were experimentally impacted on the liver with BIM IV bio impact machine. Liver imaging was performed with 99m Tc labeled sodium phytate. Liver blood pool imaging was performed with 99m Tc stannous pyrophosphate labeled red blood cells. The results of radionuclide imaging were compared with the anatomic results. Results: There was significant difference between the images of the injured liver and the control. Radio diminution and defect were shown in the injured liver areas. Various sorts of abnormal radioactivity distribution were observed with hepatic blood pool imaging. The results of the liver imaging and liver blood pool imaging were accorded with the results of the anatomic findings. Conclusions: Radionuclide imaging may well display the changes of hepatocellular structures and functions after injury, which is valuable in locating the concrete injured position and differentiating the injured degrees of liver.展开更多
文摘Molecular imaging(MI)can provide not only structural images using traditional imaging techniques but also functional and molecular information using many newly emerging imaging techniques.Over the past decade,the utilization of nanotechnology in MI has exhibited many significant advantages and provided new opportunities for the imaging of living subjects.It is expected that multimodality nanoparticles(NPs)can lead to precise assessment of tumor biology and the tumor microenvironment.This review addresses topics related to engineered NPs and summarizes the recent applications of these nanoconstructs in cancer optical imaging,ultrasound,photoacoustic imaging,magnetic resonance imaging(MRI),and radionuclide imaging.Key challenges involved in the translation of NPs to the clinic are discussed.
文摘Objective: To investigate the role and clinical value of radionuclide imaging in hepatic impact injuries in rabbits. Methods: Rabbits were experimentally impacted on the liver with BIM IV bio impact machine. Liver imaging was performed with 99m Tc labeled sodium phytate. Liver blood pool imaging was performed with 99m Tc stannous pyrophosphate labeled red blood cells. The results of radionuclide imaging were compared with the anatomic results. Results: There was significant difference between the images of the injured liver and the control. Radio diminution and defect were shown in the injured liver areas. Various sorts of abnormal radioactivity distribution were observed with hepatic blood pool imaging. The results of the liver imaging and liver blood pool imaging were accorded with the results of the anatomic findings. Conclusions: Radionuclide imaging may well display the changes of hepatocellular structures and functions after injury, which is valuable in locating the concrete injured position and differentiating the injured degrees of liver.
