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^(99)Tc^(m)-O_(4)^(-)SPECT/CT放射性摄取靶区勾画方法的定量准确性分析 被引量:1
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作者 邓惠兴 吉婷 +1 位作者 王岐 杨爱民 《中国医学装备》 2021年第9期38-42,共5页
目的:比较CT和核医学(NM)阈值两种方法勾画高鍀酸盐(99Tcm-O4-)单光子发射型电子计算机断层扫描/CT(^(99)Tc^(m)-O_(4)^(-)SPECT/CT)放射性靶区,确定99Tcm-O4-SPECT/CT高摄取病灶的最佳NM阈值。方法:采用美国电气制造商协会与国际电工... 目的:比较CT和核医学(NM)阈值两种方法勾画高鍀酸盐(99Tcm-O4-)单光子发射型电子计算机断层扫描/CT(^(99)Tc^(m)-O_(4)^(-)SPECT/CT)放射性靶区,确定99Tcm-O4-SPECT/CT高摄取病灶的最佳NM阈值。方法:采用美国电气制造商协会与国际电工委员会(NEMA/IEC)图像质量模型,对直径分别为37 mm、28 mm、22 mm、17 mm、13 mm和10 mm的6个热球以及本底分别灌注126.54 kBq/ml和7.03 kBq/ml的99Tcm-O4-(球/本底比为18∶1),通过SPECT/CT进行断层图像采集和重建。于CT图像上采用球形工具勾画热球靶区感兴趣体积(VOI);并于SPECT图像上采用NM阈值方法勾画热球靶区VOI,阈值范围为10%~90%,间隔5%。以热球实际体积为“金标准”,确定最佳NM阈值。采用曲线拟合分析最佳NM阈值与热球大小之间的关系。结果:热球靶区VOI勾画的准确性和定量准确性受勾画方法和热球大小的影响。最佳NM阈值(热球直径由小到大)分别为80%、70%、60%、50%、45%和40%。与CT勾画方法比较,最佳NM阈值方法勾画热球VOI与实际体积更接近,误差为-5.9%~-16.7%。曲线拟合分析结果显示,最佳NM阈值与热球直径之间呈非线性相关,函数关系为幂函数形式,预估曲线模型为:y=2.8065x^(-0.546),R^(2)=0.99(P<0.001)。最佳NM阈值方法勾画的定量准确性更高,其平均恢复系数(RC_(mean))分别为0.29、0.55、0.72、0.82、0.89和0.93(热球直径由小到大)。结论:对于^(99)Tc^(m)-O_(4)^(-)SPECT/CT显像,与CT勾画方法比较,最佳NM阈值方法在靶区VOI测定和SPECT/CT定量方面是一种更为精确的测量方法,最佳NM阈值与病灶大小之间的函数关系为临床准确勾画病灶靶区VOI提供了可靠依据。 展开更多
关键词 单光子发射型电子计算机断层扫描(SPECT/CT) 感兴趣体积(VOI) 放射性摄取靶 勾画
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放射性地质区隧道勘测与辐射防护设计
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作者 谭天昆 《隧道建设》 1996年第3期11-14,共4页
对放射性地质区,线路一般均以绕避为原则。但因方案比选受诸多因素的制约,不能绕避且必须通过,而又能运用技术手段采取合理防护并不需付出昂贵代价和不致使施工、运营管理条件严重恶化时,可以在放射性地质区选择适当位置通过。尤其是以... 对放射性地质区,线路一般均以绕避为原则。但因方案比选受诸多因素的制约,不能绕避且必须通过,而又能运用技术手段采取合理防护并不需付出昂贵代价和不致使施工、运营管理条件严重恶化时,可以在放射性地质区选择适当位置通过。尤其是以隧道方案通过放射性地质区时,应充分发挥和利用隧道路线方案的优点,趋利避害。 展开更多
关键词 隧道 勘测 辐射防护 设计 放射性地质
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股骨头缺血性坏死的放射性核素骨显像诊断
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作者 许树元 庞祥俊 +1 位作者 孙中洋 梁鸿举 《医学影像学杂志》 1994年第1期30-63,共2页
股骨头缺血性坏死的早期诊断和治疗是保留和恢复髋关节功能的关键。核素骨显象对本病的早期诊断提供了灵敏可靠的手段。我院自1991年至1993年与山东医科大学核医学教研室合作对31例股骨头缺血性坏死患者行核素骨显象诊断和治疗后观察。... 股骨头缺血性坏死的早期诊断和治疗是保留和恢复髋关节功能的关键。核素骨显象对本病的早期诊断提供了灵敏可靠的手段。我院自1991年至1993年与山东医科大学核医学教研室合作对31例股骨头缺血性坏死患者行核素骨显象诊断和治疗后观察。现将有关资料分析如下: 展开更多
关键词 山东医科大学 医学教研室 放射性缺损 早期诊断 股骨颈骨折 骨坏死 骨盆正位片 右侧股骨 新骨形成 组织修复
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分泌AFP肿瘤、分泌CEA肿瘤和卵巢癌的放射免疫显象
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作者 朱晓鸣 王世真 +7 位作者 周前 杨梅芳 马惠珍 刘广大 胡秀凤 连利娟 刘文书 夏振民 《中国医学科学院学报》 CAS 1987年第2期140-143,共4页
放射免疫显象技术的出现,为肿瘤的诊断、定位、预后和疗效判断以及随访提供了新的手段,是一项很有发展前途的新技术。国外对其研究正方兴未艾,在国内,我们首先报道了分泌AFP肿瘤放射免疫显象。本研究报告I标记抗CEA单克隆抗体在移植人... 放射免疫显象技术的出现,为肿瘤的诊断、定位、预后和疗效判断以及随访提供了新的手段,是一项很有发展前途的新技术。国外对其研究正方兴未艾,在国内,我们首先报道了分泌AFP肿瘤放射免疫显象。本研究报告I标记抗CEA单克隆抗体在移植人结肠癌裸鼠的体内定位,I标记抗AFP多克隆抗体、抗卵巢癌多克隆抗体和抗CEA单克隆抗体的临床应用。 展开更多
关键词 显象 放射性浓聚 卵巢上皮癌 标记抗体 AFP CEA 放射免疫 分泌 卵巢癌 卵巢恶性肿瘤 卵巢肿瘤
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^(131)I—HIPDM肺显像剂的初步临床应用
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作者 金稚奎 杨孙超 +3 位作者 曾琴 周鑫官 柯庆香 邵鹤生 《中国临床医学影像杂志》 CAS 1991年第3期154-156,共3页
<sup>131</sup>I—[N,N,N<sup>1</sup>—三甲基—N<sup>1</sup>—(2—羟基—3—甲基—5—碘苄基)—1,3—丙二胺]简称<sup>131</sup>I—HIPDM,为亲脂二胺类衍生物,作为一种脑灌注显... <sup>131</sup>I—[N,N,N<sup>1</sup>—三甲基—N<sup>1</sup>—(2—羟基—3—甲基—5—碘苄基)—1,3—丙二胺]简称<sup>131</sup>I—HIPDM,为亲脂二胺类衍生物,作为一种脑灌注显像剂早已成功地用于临床。随后日本Yamamoto相继在鼠和人用<sup>123</sup>I—HIPDM作胰腺显像获得成功。国内用<sup>123</sup>I—HIPDM作胰腺显像已有报导。由于<sup>131</sup> 展开更多
关键词 显像剂 HIPDM 临床应用 放射性缺损 Yamamoto 左肺门 放射性分布 放射性摄取 内皮细胞 淋巴结肿大
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晚期肺癌支气管动脉灌注化疗并不同剂量分割放疗近期疗效观察
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作者 王明龙 郭灵 +2 位作者 詹志光 梅泽高 陈应瑞 《实用医学杂志》 CAS 1994年第9期808-809,共2页
晚期肺癌支气管动脉灌注化疗并不同剂量分割放疗近期疗效观察广东省人民医院放疗科王明龙,郭灵,詹志光,梅泽高,陈应瑞晚期肺癌失去了手术机会,放射治疗和化疗虽有一定疗效,但以综合治疗为首选(1)。我院自1990年1月至19... 晚期肺癌支气管动脉灌注化疗并不同剂量分割放疗近期疗效观察广东省人民医院放疗科王明龙,郭灵,詹志光,梅泽高,陈应瑞晚期肺癌失去了手术机会,放射治疗和化疗虽有一定疗效,但以综合治疗为首选(1)。我院自1990年1月至1993年3月对120例晚期肺癌行支气... 展开更多
关键词 剂量分割 近期疗效观察 放射治疗 中央型肺癌 支气管动脉灌注 晚期肺癌患者 气管瘘 小细胞未分化癌 脑转移 放射性浓聚
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^(99m)Tm-MDP骨显像诊断多发性骨髓瘤2例报道 被引量:1
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作者 崔彬 王振辉 杨丽霞 《现代诊断与治疗》 CAS 2012年第12期2271-2271,共1页
总结99mTm-MDP骨显像诊断多发性骨髓瘤2例的经验。
关键词 多发性骨髓瘤 m)Tm-MDP骨显像 本周蛋白 放射性增高 溶骨性 胸锁关节 受照射剂量 myeloma 扁平骨 放射性摄取
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阿米巴肝脓肿误诊为原发性肝癌的原因分析
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作者 焦文举 李明荣 张磊 《黑龙江医药》 CAS 1989年第6期56-56,共1页
近年来,阿米巴肝脓肿的发病率在我省已显著下降。因此,许多临床医生对此病已逐渐失去了警惕性。对那些散发的阿米巴肝脓肿病例往往不能及时确诊,甚至造成误诊。本院自1978~1988年收治的阿米巴肝脓肿误诊为原发性肝癌5例,报道如下:临床... 近年来,阿米巴肝脓肿的发病率在我省已显著下降。因此,许多临床医生对此病已逐渐失去了警惕性。对那些散发的阿米巴肝脓肿病例往往不能及时确诊,甚至造成误诊。本院自1978~1988年收治的阿米巴肝脓肿误诊为原发性肝癌5例,报道如下:临床资料5例中男3例,女2例。平均年龄45岁。 展开更多
关键词 阿米巴肝脓肿 原发性肝癌 临床医生 病已 中男 肠阿米巴病 甲胎蛋白 临床资料 病例摘要 放射性缺损
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Marine and Inland Water Resources in Eneolithic Communities. New Data from Sardinia (Italy)
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作者 Maria Grazia Melis Marco Zedda Laura Manca 《Journal of Life Sciences》 2012年第6期679-693,共15页
This paper presents research aimed at identifying the methods with which prehistoric man interacted with marine and inland water environments. The objective is to determine the degree to which resources from these env... This paper presents research aimed at identifying the methods with which prehistoric man interacted with marine and inland water environments. The objective is to determine the degree to which resources from these environments influenced the socio-economic organization of these peoples. The coastline around Cagliari and its hinterland (southern Sardinia, Italy) were chosen as the subject, on the basis of the presence of both the sea and several ponds. The territory is noted as being home to both Neolithic and Eneolithic settlements. Among these the archaeological excavation of the village of Su Coddu/Canelles produced a large quantity of malacofauna. Data has been processed from part of the settlement that gave radiocarbon dating from the period between 3640 and 2900 cal. BC, and in which it was possible to carry out the level of sampling that was necessary to complete the research. In particular this interdisciplinary project, which aims to make an overall study of the settlement, the data relating to the geography of the area, the archaeological documentation, the fauna and shell artefacts will be extrapolated. Numerous methods are applied above all in reference to the marines and ponds resources. Additionally, the morphological anatomical-comparative analysis (in order to determine the typology of the faunal remains and to identify each individual species) and the technological analysis of the manufactured shells (so as to detect the selection and the transformation type of raw materials) are accomplished. The research has led to the identification of a settlement model in which agriculture formed the primary means of subsistence, that was complemented by the rearing of livestock, through hunting and gathering. The exploitation of marine and inland waters resources, as food source, have to be important because 99% of the faunal remains are shells. Different shell species are recognized, among those the Ostrea edulis provides the raw material to produce bevelled objects, which are documented inside the settlement in considerable number. Some plant species, typical of the lagoon ecosystem, were used for building and craft production. 展开更多
关键词 SARDINIA Eneolithic PALEO-ENVIRONMENT archaeozoology production of shell artefacts resources of sea and inland waters.
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Experimental Studies on Penetration of Pulverized Clay-Based Grout
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作者 T. Fujita Y. Sugita M. Toida 《Journal of Energy and Power Engineering》 2011年第5期419-427,共9页
For the geological disposal of high level radioactive wastes, an excavation damaged zone (EDZ) having high hydraulic conductivity resulting from the development of fractures in the rock adjacent to the tunnels will ... For the geological disposal of high level radioactive wastes, an excavation damaged zone (EDZ) having high hydraulic conductivity resulting from the development of fractures in the rock adjacent to the tunnels will be one of the potential pathways for radioactive contaminant transport. The potential pathways will be sealed by closure components, that is, a combination of tunnel plug, backfill and grout, the latter material being a clay-based mixture in consideration of the need for long-term stability of the seals. Clay-based grout is one of the effective candidate materials that can be used to interrupt the migration of radionuclides through an EDZ. Laboratory testing of clay-based grout using pulverized bentonite, with the objective of improvement in grout penetration into a rockmass, was conducted. The results showed that the pulverization of clay-based grout had a positive effect on filtration. 展开更多
关键词 High-level radioactive waste geological disposal repository sealing GROUT clay-based bentonite pulverization.
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“光明杀手”——世纪未的话题
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作者 每文 《健康》 1999年第5期5-7,共3页
人们总是希冀着世界一片光明。可真要那样的话,世界也就大祸临头了。上古时代,天空突然出现了十个太阳,一时之间,到处明晃晃一片,开无分昼夜,人脚下无影,大地热浪滚滚,人人惶恐不安。这时出现了一位大英雄后羿。他用强弓一连射下了九个... 人们总是希冀着世界一片光明。可真要那样的话,世界也就大祸临头了。上古时代,天空突然出现了十个太阳,一时之间,到处明晃晃一片,开无分昼夜,人脚下无影,大地热浪滚滚,人人惶恐不安。这时出现了一位大英雄后羿。他用强弓一连射下了九个太阳,才把人们从水深火热之中拯救出来。光明太多了,不见得就是件好事。在古希腊,有一次敌人庞大的舰队来犯,城市里只剩下些妇孺。天才的物理学家阿基米德便让全城的妇女集中到海岸边,用她们手里的梳妆镜把阳光聚集到敌船的风帆上。敌船着火,不战自乱,全城这才逃过一场大难。如此看来,阳光亦有杀伤力。 展开更多
关键词 玻璃幕墙 光污染 霓虹灯 日光 金属钻 心理情绪 放射性区 繁华城 焦点温度 太阳
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^((99)~m)锝闪烁扫描对小儿肠重复畸形致消化道出血的诊断
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作者 白国卿 刘丹 李心元 《中国实用儿科杂志》 1988年第2期-,共1页
小儿肠重复畸形在临床上并非少见,由于它在肠道的发生部位、形态、大小及种类不同,临床表现极其复杂,其中小管状肠重复畸形主要表现为下消化道出血,临床确定诊断十分困难。我院从1984年以来采用99m锝肠扫描,有7例下消化道出血病儿确诊... 小儿肠重复畸形在临床上并非少见,由于它在肠道的发生部位、形态、大小及种类不同,临床表现极其复杂,其中小管状肠重复畸形主要表现为下消化道出血,临床确定诊断十分困难。我院从1984年以来采用99m锝肠扫描,有7例下消化道出血病儿确诊为肠重复畸形,并经手术及病理检查证实。我们认为99m锝扫描对肠重复畸形有一定诊断意义,现报告如下。 展开更多
关键词 肠重复畸形 放射性浓聚 小儿
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肺栓塞的诊断
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作者 王文中 《中国医师进修杂志》 1989年第7期32-33,共2页
肺栓塞指栓子阻塞肺动脉造成的病理过程,为一常见肺部疾患。是内、外、妇产等科均可遇到的一种严重并发症。有关诊断的检测技术如肺血或造影等开展很少,故难能确诊。为提高诊断,恰当防治,本文对国内外有关肺栓塞诊断近况加以复习。一、... 肺栓塞指栓子阻塞肺动脉造成的病理过程,为一常见肺部疾患。是内、外、妇产等科均可遇到的一种严重并发症。有关诊断的检测技术如肺血或造影等开展很少,故难能确诊。为提高诊断,恰当防治,本文对国内外有关肺栓塞诊断近况加以复习。一、临床表现在诊断中的意义临床表现与病理过程通常较为一致。从病理上看,栓子可以是单个巨大血栓,或是广泛微小血栓、瘤栓。栓子可以阻塞一支大动脉,或骑跨阻塞两支较大动脉,也可广泛阻塞许多细小动脉。由于肺循环血供丰富,肺组织供氧来源亦丰富,它接受(1)肺动脉系,(2)支气管动脉系, 展开更多
关键词 肺栓塞 栓子阻塞 支气管动脉 瘤栓 肺梗塞 血供 小动脉 肺部疾患 放射性缺损 动脉系
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Underestimated ^(14)C-based chronology of late Pleistocene high lake-level events over the Tibetan Plateau and adjacent areas: Evidence from the Qaidam Basin and Tengger Desert 被引量:13
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作者 LONG Hao SHEN Ji 《Science China Earth Sciences》 SCIE EI CAS CSCD 2015年第2期183-194,共12页
The palaeolake evolution across the Tibetan Plateau and adjacent areas has been extensively studied, but the timing of late Pleistocene lake highstands remains controversial. Robust dating of lacustrine deposits is of... The palaeolake evolution across the Tibetan Plateau and adjacent areas has been extensively studied, but the timing of late Pleistocene lake highstands remains controversial. Robust dating of lacustrine deposits is of importance in resolving this issue. This paper presents 14 C or optically stimulated luminescence(OSL) age estimates from two sets of late Quaternary lacustrine sequences in the Qaidam Basin and Tengger Desert(northeastern Tibetan Plateau). The updated dating results show:(1) the radiocarbon dating technique apparently underestimated the age of the strata of >30 ka BP in Qaidam Basin;(2) although OSL and 14 C dating agreed with each other for Holocene age samples in the Tengger Desert area, there was a significant offset in dating results of sediments older than ~30 ka BP, largely resulting from radiocarbon dating underestimation;(3) both cases imply that most of the published radiocarbon ages(e.g., older than ~30 ka BP) should be treated with caution and perhaps its geological implication should be revaluated; and(4) the high lake events on the Tibetan Plateau and adjacent areas, traditionally assigned to MIS 3a based on 14 C dating, are likely older than ~80 ka based on OSL chronology. 展开更多
关键词 dating Plateau Desert Tibetan older Pleistocene Holocene lacustrine dated quartz
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广角镜
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《兵器知识》 1994年第4期19-19,共1页
泄露军机的玩具美国隐形战斗机F-117A自1983年交付使用后,对外界一直保密。直到1988年11月,军方才公布了它的外形照片,使该机初露庐山真面目。但在1986年举行的玩具博览会上,美一家公司推出了一种自称是F-19隐形战斗机的玩具模型,当即... 泄露军机的玩具美国隐形战斗机F-117A自1983年交付使用后,对外界一直保密。直到1988年11月,军方才公布了它的外形照片,使该机初露庐山真面目。但在1986年举行的玩具博览会上,美一家公司推出了一种自称是F-19隐形战斗机的玩具模型,当即引起原苏联等国的兴趣,他们纷纷派人购买。美国情报机构看后大吃一惊,因为该玩具竟与F-117A真实飞机极其相似。美军以涉嫌国家机密为由进行了追究。原来,该模型的设计者是一位当过飞行员的工程师。他声称。 展开更多
关键词 情报机构 导弹工业 日本爱知 地对空导弹 多国部队 放射性沾染 小牧 日本三菱重工 大城市 导弹研制
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科技前沿
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《军事文摘》 2016年第12期18-21,共4页
中国小白菜要到天上种植国际空间站要种中国的小白菜啦!目前,白菜种子已于2016年4月8日前被送往国际空间站。在国际空间站上培育蔬菜是NASA(美国国家航空航天局)空间站计划的一部分,旨在准备时间更长更远的太空飞行,同时也是为了丰富乘... 中国小白菜要到天上种植国际空间站要种中国的小白菜啦!目前,白菜种子已于2016年4月8日前被送往国际空间站。在国际空间站上培育蔬菜是NASA(美国国家航空航天局)空间站计划的一部分,旨在准备时间更长更远的太空飞行,同时也是为了丰富乘员的饮食。NASA在选择植物时所遵循的原则是。 展开更多
关键词 国际空间站 准备时间 白菜种子 科技前沿 太空飞行 矮星系 放射性沾染 纳米材料 激光切割技术 星系团
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Estimating Soil Erosion in Northeast China Using ^(137)Cs and ^(210)Pbex 被引量:14
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作者 YANG Yu-Hong YAN Bai-Xing ZHU Hui 《Pedosphere》 SCIE CAS CSCD 2011年第6期706-711,共6页
Evaluation of soil erosion in agricultural fields is valuable to develop conservation practices for reducing agricultural nonpoint source pollution. Soil erosion rates were quantified using the fallout radionuclide tr... Evaluation of soil erosion in agricultural fields is valuable to develop conservation practices for reducing agricultural nonpoint source pollution. Soil erosion rates were quantified using the fallout radionuclide tracer technique in Mojiagou Basin located on the outskirts of Changchun in Northeast China. The calculated soft erosion rates in the study area were 1.99 and 1.85 mm year-1 using 137Cs and excess 210pb (210Pbex) measurements, respectively. Both fallout radionuclides showed a similar tendency at downslope sites. All measured sites have experienced net erosion during the past 50 to 100 years. 137Cs and 210Pbex measurements were useful to quantify soil erosion rates on field and small basin scales. At this rate of erosion, the current fertile topsoil layer would be entirely removed within 70 years. 展开更多
关键词 black soil fallout radionuclide tracer technique rainfall erosivity reference inventory soil loss
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A regional simulation study on dispersion of nuclear pollution from the damaged Fukushima Nuclear Power Plant 被引量:1
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作者 FEI JianFang WANG PengFei +2 位作者 CHENG XiaoPing HUANG XiaoGang WANG YiBai 《Science China Earth Sciences》 SCIE EI CAS 2014年第7期1513-1524,共12页
A nuclear accident involving the leaking of radioactive pollutants occurred at the Fukushima Nuclear Power Plant in Japan, following an earthquake and subsequent tsunami on March 11,2011. Using official Japanese data ... A nuclear accident involving the leaking of radioactive pollutants occurred at the Fukushima Nuclear Power Plant in Japan, following an earthquake and subsequent tsunami on March 11,2011. Using official Japanese data on pollutant emissions during the accident, this study simulates the dispersion of nuclear pollutants. The source term of the nuclear leakage of radioactive material is designed using PM2.5 as the tracer of radioactive pollutants, and the study considers dry and wet deposition processes. A coupled-model system is constructed from the air-quality model Models-3/CMAQ and the Weather Research and Forecasting atmospheric model. The transport path and distribution of radioactive pollutants over long and short distances are simulated with different model horizontal resolutions of 30 and 4 km respectively. The long-distance simulation shows that, following the Fukushima nuclear accident, under the effect of westerly winds, radioactive pollutants are transported generally towards the eastern Pacific and reach the American continent after 5 days, but their concentration is only about 10-7 times the concentration near the Fukushima Nuclear Power Plant. The time required for pollutants to reach the United States is basically consistent with measurements made in California on March 18. Because the upper westerly wind is faster than the lower westerly wind, the distribution of pollutants tilts eastward in terms of its vertical structure. The short-distance (local) highresolution simulation indicates that strong winds and precipitation associated with a cyclone can accelerate the deposition, dif- fusion and transport of pollutions, and local cyclonic circulation can change the transport path of pollutants, even resulting in repeated effects of pollution in some areas. Pollutants disperse to southeastern Honshu, Japan, on March 14, 2011, agreeing well with the timing of local observations of increases in the absorbed dose rate. Results also show that radioactive pollutants from the Fukushima nuclear accident are mainly transported and diffuse eastward, resulting in a relatively short-term impact on the Japanese mainland even under the influence of the cyclone system. Therefore, in terms of atmospheric conditions, the location of the Fukusbima Nuclear Power Plant is appropriate and could serve as a reference to site selection and protection of other nuclear facilities. 展开更多
关键词 radioactive pollutant FUKUSHIMA dispersion and transport numerical simulation
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