A new method for tile preparation of p-iodophenyl pentadecanoic acid (IPPA)has been developed. The synthesis are described, and physical properties of IPPA are characterized by IR, 1HNMR, elementary analysis and MS. 1...A new method for tile preparation of p-iodophenyl pentadecanoic acid (IPPA)has been developed. The synthesis are described, and physical properties of IPPA are characterized by IR, 1HNMR, elementary analysis and MS. 125I-IPPA can be easily prepared bytwo methods: direct labeling and solid-phase iodo-exchange labeling, and the yields of labelingare 80% and 65%, respectively. The radiochcnrical purities are higher than 98% after beingextracted with chloroform and he-cane.展开更多
文摘A new method for tile preparation of p-iodophenyl pentadecanoic acid (IPPA)has been developed. The synthesis are described, and physical properties of IPPA are characterized by IR, 1HNMR, elementary analysis and MS. 125I-IPPA can be easily prepared bytwo methods: direct labeling and solid-phase iodo-exchange labeling, and the yields of labelingare 80% and 65%, respectively. The radiochcnrical purities are higher than 98% after beingextracted with chloroform and he-cane.
