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含时滞营养再生的单种群赤潮生态数学模型 被引量:1
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作者 段美元 王寿松 《数理医药学杂志》 1999年第3期201-202,共2页
讨论了四种营养上升函数的性质。根据赤潮藻类以四种不同方式吸收营养.其快慢程度不同、定性分析了赤潮生态数学模型解的有界性和平衡点的稳定性,并企图将有关结论应用于赤潮研究。
关键词 营养上升函数 赤潮 单种群 生态效学模型 稳定性
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含移动副四杆机构运动仿真设计的数学模型 被引量:1
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作者 朱琦 《山西机械》 2003年第4期17-18,共2页
综述了计算机仿真连杆机构运动的技术特点,建立了曲柄滑块机构和导杆机构二种含移动副四杆机构运动仿真设计的数学模型。
关键词 曲柄滑块机构 仿真 效学模型 导杆机构 四杆机构
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GPS高程拟合模型确定 被引量:4
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作者 刘海燕 《内蒙古煤炭经济》 2007年第1期68-70,共3页
本文阐述了两种进行GPS水准拟合的数学模型:多项式拟合模型和多面函数曲面拟合模型。通过实例验证,结果满足四等几何水准的测量要求,并提出了GPS高程拟合模型确定的几点结论。
关键词 GPS 高程拟合 效学模型
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Research on Yield and Quality of Hybrid Rice under Efficient Application Amount of Phosphorus and Potassium 被引量:3
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作者 熊洪 徐富贤 +4 位作者 朱永川 张林 郭晓艺 刘茂 周兴兵 《Agricultural Science & Technology》 CAS 2012年第2期343-350,共8页
[Objective] Application of P and K was not reasonable in southwest rice producing area, with no effective method for guiding application of P and K. This study aimed to conduct experiments with the same N application ... [Objective] Application of P and K was not reasonable in southwest rice producing area, with no effective method for guiding application of P and K. This study aimed to conduct experiments with the same N application and different P and K application in different ecological points, to explore a scientific and efficient management method of P and K nutrients and provide guidance for application of P and K in rice production. [Method] Hybrid rice Chuanxiang9838 was used as experimental material to study the relationship among application amount of P and K, utilization rates of P and K, rice yield and rice quality in seven ecological points of four provinces (municipalities) including Sichuan, Chongqing, Yunnan and Guizhou. The application amount per hectare of P was 37.5, 75, 112.5 and 150 kg, respectively; the application amount per hectare of K was 45, 135 and 180 kg, respectively. A total of 10 treatments were set for split-plot design with three replications. [Result] Yield of Chuanxiang9838 significantly varied in different experimental locations and under different levels of P and K, interaction of ecological point and different P and K treatments varied significantly. Yield had reached the maximum in ecological point of Yunnan Binchuan and in treatment with application of N 150 kg P 75 kg K 90 kg. Efficient utilization rates of P and K varied in each ecological point, efficient application amount of P and K in Sichuan Dongpo, Sichuan Luxian, Guizhou Xiaohe and Chongqing Yongchuan was the same, while that in Sichuan Guanghan, Sichuan Zhongjiang and Yunnan Binchuan was different. The main objective of high-yield rice production was to increase the number of effective panicles per hectare and seed setting rate. Rice quality was clustered into 2 categories by locations and 6 categories by treatments. [Conclusion] Prediction models of efficient application of P and K in rice production were established, which provided guidance for high-yield rice production and rational and efficient utilization of P and K in southwest rice area. 展开更多
关键词 Phosphorus and potassium nutrients Efficient application amount Mathematic model Mid-season hybrid rice
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HYBRID APPROACH FOR ESTIMATING COUPLING EFFECT BETWEEN PROPELLANT SLOSHING DYNAMIC AND SPACECRAFT GNC
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作者 齐乃明 董锴 +1 位作者 李运迁 赵宝山 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI 2009年第2期137-146,共10页
An approach based on equivalent mechanics theory and computational fluid dynamics (CFD) technology is proposed to estimate dynamical influence of propellant sloshing on the spacecraft. A mechanical model is estab- l... An approach based on equivalent mechanics theory and computational fluid dynamics (CFD) technology is proposed to estimate dynamical influence of propellant sloshing on the spacecraft. A mechanical model is estab- lished by using CFD technique and packed as a "sloshing" block used in spacecraft guidance navigation and control (GNC) simulation loop. The block takes motion characteristics of the spacecraft as inputs and outputs of pertur- bative force and torques induced by propellant sloshing, thus it is more convenient for analyzing coupling effect between propellant sloshing dynamic and spacecraft GNC than using CFD packages. An example demonstrates the accuracy and the superiority of the approach. Then, the deducing process is applied to practical cases, and simulation results validate that the proposed approach is efficient for identifying the problems induced by sloshing and evaluating effectiveness of several typical designs of sloshing suppression. 展开更多
关键词 equivalent mechanical model computational fluid dynamics(CFD)technique propellant sloshing
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Bayesian analysis for mixed-effects model defined by stochastic differential equations
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作者 言方荣 张萍 +1 位作者 陆涛 林金官 《Journal of Southeast University(English Edition)》 EI CAS 2014年第1期122-127,共6页
The nonlinear mixed-effects model with stochastic differential equations (SDEs) is used to model the population pharmacokinetic (PPK) data that are extended from ordinary differential equations (ODEs) by adding ... The nonlinear mixed-effects model with stochastic differential equations (SDEs) is used to model the population pharmacokinetic (PPK) data that are extended from ordinary differential equations (ODEs) by adding a stochastic term to the state equation. Compared with the ODEs, the SDEs can model correlated residuals which are ubiquitous in actual pharmacokinetic problems. The Bayesian estimation is provided for nonlinear mixed-effects models based on stochastic differential equations. Combining the Gibbs and the Metropolis-Hastings algorithms, the population and individual parameter values are given through the parameter posterior predictive distributions. The analysis and simulation results show that the performance of the Bayesian estimation for mixed-effects SDEs model and analysis of population pharmacokinetic data is reliable. The results suggest that the proposed method is feasible for population pharmacokinetic data. 展开更多
关键词 population pharmacokinetics mixed-effectsmodels stochastic differential equations Bayesian analysis
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A pharmacodynamic model of portal hypertension in isolated perfused rat liver 被引量:2
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作者 Tao Zhang Xue-Yan Xu +7 位作者 Hang Zhou Xin Zhao Meng Song Tao-Tao Zhang He Yin Ting Li Peng-Tao Li Da-Yong Cai 《World Journal of Gastroenterology》 SCIE CAS CSCD 2012年第5期472-478,共7页
AIM: To develop a pharmacodynamic model of porta hypertension from chronic hepatitis. METHODS: Pathological changes and collagen depositions were analyzed using morphometry to confirm CCI4-induced chronic hepatitis.... AIM: To develop a pharmacodynamic model of porta hypertension from chronic hepatitis. METHODS: Pathological changes and collagen depositions were analyzed using morphometry to confirm CCI4-induced chronic hepatitis. At do, d28, ds6 and d84 of the process, the portal perfused velocities (μL/min) in isolated rat livers were exactly controlled with a quanti-fied pump. The pressure (mmHg) was monitored with a Physiological System. The geometric concentrations of phenylephrine or acetylcholine were added to a fixed volume (300 mL) of the circulating perfusate. The equation, the median effective concentration and its 95% confidence intervals of phenylephrine or acetyl- choline were regressed with Prism-4 software in non-linear fit and various slopes. In the isolated perfused rat livers with chronic hepatitis, both median effective concentrations were defined as the pharmacodynamic model of portal hypertension.CONCLUSION: A pharmacodynamic model of portal hypertension in isolated perfused rat livers with chronic hepatitis was defined as the median effective concen- trations of phenylephrine and acetylcholine. 展开更多
关键词 Chronic hepatitis Isolated portal perfusedrat liver Pharmacodynamic model Portal hypertension
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Numerical Investigation on 1,3-Butadiene/Propyne Co-pyrolysis and Insight into Synergistic Effect on Aromatic Hydrocarbon Formation
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作者 李天宇 邹家标 +3 位作者 张言 曹创创 李伟 苑文浩 《Chinese Journal of Chemical Physics》 SCIE CAS CSCD 2017年第3期287-294,I0001,共9页
A numerical investigation on the co-pyrolysis of 1,3-butadiene and propyne is performed to explore the synergistic effect between fuel components on aromatic hydrocarbon formation. A detailed kinetic model of 1,3-buta... A numerical investigation on the co-pyrolysis of 1,3-butadiene and propyne is performed to explore the synergistic effect between fuel components on aromatic hydrocarbon formation. A detailed kinetic model of 1,3-butadiene/propyne co-pyrolysis with the sub-mechanism of aromatic hydrocarbon formation is developed and validated on previous 1,3-butadiene and propyne pyrolysis experiments. The model is able to reproduce both the single component pyrolysis and the co-pyrolysis experiments, as well as the synergistic effect between 1,3- butadiene and propyne on the formation of a series of aromatic hydrocarbons. Based on the rate of production and sensitivity analyses, key reaction pathways in the fuel decomposition and aromatic hydrocarbon formation processes are revealed and insight into the synergistic effect on aromatic hydrocarbon formation is also achieved. The synergistic effect results from the interaction between 1,3-butadiene and propyne. The easily happened chain initiation in the 1,3-butadiene decomposition provides an abundant radical pool for propyne to undergo the H-atom abstraction and produce propargyl radical which plays key roles in the formation of aromatic hydrocarbons. Besides, the 1,3-butadiene/propyne co-pyrolysis includes high concentration levels of C3 and C4 precursors simultaneously, which stimulates the formation of key aromatic hydrocarbons such as toluene and naphthalene. 展开更多
关键词 1 3-BUTADIENE PROPYNE Kinetic model Synergistic effect Aromatic hydro-carbon formation
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Numerical method of slope failure probability based on Bishop model 被引量:3
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作者 苏永华 赵明华 张月英 《Journal of Central South University of Technology》 EI 2008年第1期100-105,共6页
Based on Bishop's model and by applying the first and second order mean deviations method, an approximative solution method for the first and second order partial derivatives of functional function was deduced acc... Based on Bishop's model and by applying the first and second order mean deviations method, an approximative solution method for the first and second order partial derivatives of functional function was deduced according to numerical analysis theory. After complicated multi-independent variables implicit functional function was simplified to be a single independent variable implicit function and rule of calculating derivative for composite function was combined with principle of the mean deviations method, an approximative solution format of implicit functional function was established through Taylor expansion series and iterative solution approach of reliability degree index was given synchronously. An engineering example was analyzed by the method. The result shows its absolute error is only 0.78% as compared with accurate solution. 展开更多
关键词 Bishop mechanical model failure probability of slope mean deviation method implicit function Taylor series dump of open-pit
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The single-machine scheduling problems with deteriorating jobs and learning effect 被引量:12
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作者 CHENG Ming-bao SUN Shi-jie 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 SCIE EI CAS CSCD 2006年第4期597-601,共5页
In this paper we consider a single-machine scheduling model with deteriorating jobs and simultaneous learning, and we introduce polynomial solutions for single machine makespan minimization, total flow times minimizat... In this paper we consider a single-machine scheduling model with deteriorating jobs and simultaneous learning, and we introduce polynomial solutions for single machine makespan minimization, total flow times minimization and maximum lateness minimization corresponding to the first and second special cases of our model under some agreeable conditions. However, corresponding to the third special case of our model, we show that the optimal schedules may be different from those of the classical version for the above objective functions. 展开更多
关键词 SCHEDULING SINGLE-MACHINE Learning effect Deteriorating jobs
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Maximum Effective Hole Mathematical Modei and Exact Solution for Commingled Reservoir 被引量:2
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作者 孙贺东 刘磊 +1 位作者 周芳德 高承泰 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2003年第5期550-554,共5页
The maximum effective hole-diameter mathematical modei describing the flow of slightly compressible fluid through a commingled reservoir was solved rigorously with consideration of wellbore storage and different skin ... The maximum effective hole-diameter mathematical modei describing the flow of slightly compressible fluid through a commingled reservoir was solved rigorously with consideration of wellbore storage and different skin factors. The exact solutions for wellbore pressure and the production rate obtained from layer j for a well production at a constant rate from a radial drainage area with infinite and constant pressure and no flow outer boundary condition were expressed in terms of ordinary Bessel functions. These solutions were computed numerically by the Crump's numerical inversion method and the behavior of systems was studied as a function of various reservoir parameters. The modei was compared with the real wellbore radii modei. The new modei is numerically stable when the skin factor is positive and negative, but the real wellbore radii modei is numerically stable only when the skin factor is positive. 展开更多
关键词 well-testing mathematical model effective hole diameter layered reservoir
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Compression behavior and constitutive model establishment of fly ash cenosphere/polyurethane aluminum alloy syntactic foam 被引量:2
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作者 XU Peng WANG Yonghuan 《Journal of Measurement Science and Instrumentation》 CAS CSCD 2021年第3期369-378,共10页
The aluminum matrix syntactic foam was fabricated by pressure infiltration technique,and the filling material is syntactic foam material with fly ash cenosphere as the main component and polyurethane foam as the binde... The aluminum matrix syntactic foam was fabricated by pressure infiltration technique,and the filling material is syntactic foam material with fly ash cenosphere as the main component and polyurethane foam as the binder.Split Hopkinson pressure bar(SHPB)dynamic compression and quasi-static tests were carried out to examine the compressive response of syntactic foam in this study.Then the dynamic constitutive model was established.Results show that the compressive stress-strain curve of syntactic aluminum foam is similar to that of other metallic foam materials:both kinds of aluminum matrix syntactic foams have strain rate effect,and the syntactic foam has higher compressive strength and energy absorption than the same density aluminum foams.However,due to the different sizes of cenospheres,the dynamic compression results of two kinds of syntactic foams are different,and the energy absorption effect of syntactic foam with small size under dynamic impact is the best.In the range of strain rate and density studied experimentally,the curves of constitutive model fit well with the curves of experimental data. 展开更多
关键词 fly ash cenosphere POLYURETHANE composite foam aluminum strain rate effect mechanical property constitutive model
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Mathematical model analysis of new-type magnetic integrated CRT considering magnetic leakage
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作者 WANG Tiange TIAN Mingxing ZHANG Huiying 《Journal of Measurement Science and Instrumentation》 CAS CSCD 2022年第1期31-40,共10页
A novel magnetic integrated controllable reactor of transformer type(CRT)has the advantages of simple structure,flexible assembly,convenient maintenance and practicability.To analyze its operation characteristics accu... A novel magnetic integrated controllable reactor of transformer type(CRT)has the advantages of simple structure,flexible assembly,convenient maintenance and practicability.To analyze its operation characteristics accurately,we establish corresponding equivalent mathematical model considering magnetic leakage based on magnetic circuit and circuit dualistic transformation method.The distribution of magnetic leakage field of each winding is analyzed qualitatively,and the analytical calculation formulas of magnetizing inductance and leakage inductance of each winding are derived.Based on this,the analytical calculation formulas of short-circuit impedance and winding current of CRT under different working conditions are derived.The field-circuit coupling finite element model of the magnetic integrated CRT is established to simulate the current of each winding under different working conditions.The results show that the analytical calculation results of each winding current have good consistency with the finite element calculation results,indicating the validity of CRT equivalent mathematical model and correctness of the analytical formulas of leakage inductance,short-circuit impedance and winding current of CRT.The working winding current of CRT is increasing gradually with the operation of control winding in turn to realise the transition of CRT compensation capacity from zero to a rated value. 展开更多
关键词 controllable reactor of transformer type(CRT) magnetic integration technology equivalent mathematical model leakage inductance winding current
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Dynamic simulation and efficiency analysis of beam pumping system 被引量:3
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作者 邢明明 董世民 +2 位作者 童志雄 田然凤 陈慧玲 《Journal of Central South University》 SCIE EI CAS CSCD 2015年第9期3367-3379,共13页
An improved whole model of beam pumping system was built. In the detail, for surface transmission system(STS), a new mathematical model was established considering the influence of some factors on the STS's torsio... An improved whole model of beam pumping system was built. In the detail, for surface transmission system(STS), a new mathematical model was established considering the influence of some factors on the STS's torsional vibration, such as the time variation characteristic of equivalent stiffness of belt and equivalent rotational inertia of crank. For the sucker rod string(SRS), an improved mathematical model was built considering the influence of some parameters on the SRS's longitudinal vibration, such as the nonlinear friction of plunger, hydraulic loss of pump and clearance leakage. The dynamic response and system efficiency of whole system were analyzed. The results show that there is a jumping phenomenon in the amplitude frequency curve, and the system efficiency is sensitive to motor power, pump diameter, stroke number, ratio of gas and oil, and submergence depth. The simulation results have important significance for improving the efficiency of beam pumping system. 展开更多
关键词 beam pumping system surface transmission system(STS) sucker rod string(SRS) system efficiency dynamic simulation
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The Adsorption of Phenol by Lignite Activated Carbon 被引量:5
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作者 吕国诚 郝娇 +5 位作者 刘瑠 马鸿文 方勤方 吴丽梅 魏铭泉 张以河 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2011年第3期380-385,共6页
The feasibility and adsorption effect of lignite activated carbon for phenol removal from aqueous solutions were evaluated and investigated. A series of tests were performed to look into the influence of various exper... The feasibility and adsorption effect of lignite activated carbon for phenol removal from aqueous solutions were evaluated and investigated. A series of tests were performed to look into the influence of various experimental parameters such as contact time, initial phenol concentration, temperature, and pH value on the adsorption of phenol by lignite activated carbon. The experimental data were fitted well with the pseudo-second-order kinetic model. The adsorption is an endothermic process and conforms to Freundlich thermodynamic model. The results indicate that the lignite activated carbon is suitable to be used as an adsorbent material for adsorption of phenol from aqueous solutions. 展开更多
关键词 ADSORPTION lignite activated carbon PHENOL
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Investigation of acoustic scale effects and boundary effects for the similitude model of underwater complex shell-structure 被引量:3
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作者 WANG San-de YANG De-sen LIU Ning 《Journal of Marine Science and Application》 2007年第1期31-35,共5页
In this paper, the acoustic scale effects and boundary effects for the similitude model of underwater complex shell-structure are investigated. The similitude conditions and relations between the similitude model and ... In this paper, the acoustic scale effects and boundary effects for the similitude model of underwater complex shell-structure are investigated. The similitude conditions and relations between the similitude model and its prototype were studied in the references. This paper investigates the acoustic scale effects for the similitude model, which are influenced by loss factor, shear and rotatory inertia. At the same time, the boundary effects which are influenced by surface sound reflection are investigated in the experiment of similitude model. The results show that the acoustic scale effects may be controlled with model designing, the boundary effects can be controlled with experimental designing between the similitude model and its prototype. 展开更多
关键词 acoustic scale effects acoustic boundary effects SIMILITUDE
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Stability analysis of the rotating tribological pair system on circular-disc end faces
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作者 Chen Long Zhang Jianrun 《Journal of Southeast University(English Edition)》 EI CAS 2020年第1期24-31,共8页
In order to study the stability of friction and contact of the rotating tribological pair system,considering the influence of the changeable factors on the stability,the system dynamics analysis model based on the Lag... In order to study the stability of friction and contact of the rotating tribological pair system,considering the influence of the changeable factors on the stability,the system dynamics analysis model based on the Lagrange equation is firstly established.The surface contact stiffness model is determined on the basis of the fractal theory.The model of the friction torque with velocities is created by using the Stribeck friction effect.The Lyapunov indirect method is employed to explore the eigenvalue problem of the system state equation.The effects of the applied load,the fractal dimension,the fractal scaling coefficient and the Stribeck coefficient on the system stability are investigated in detail.The numerical simulation results demonstrate that the tribological pair system is prone to causing system instability at low speed,and the system instability boundary value decreases when the Stribeck coefficient decreases.The fractal dimension and the fractal scaling coefficient impact the system stability slightly when fractal dimensions are large,and the system instability can be reduced by properly increasing the surface smoothness.Moreover,the system instability evidently increases with the increase in the applied load and the Stribeck coefficient.These achievements can provide a reference and theoretical support for the analysis of the dynamic performance of the tribological pair system. 展开更多
关键词 rotating tribological pair system contact stiffness Stribeck effect dynamic model stability
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An equivalent-tool theory for acoustic logging and applications 被引量:4
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作者 Su Yuan-Da Tang Xiao-Ming Hei Chuang Zhuang Chun-Xi 《Applied Geophysics》 SCIE CSCD 2011年第1期69-78,96,共11页
The influence of an acoustic logging tool on borehole guided wave propagation should be considered in the processing and inversion of the guided waves for formation acoustic property estimation. This study introduces ... The influence of an acoustic logging tool on borehole guided wave propagation should be considered in the processing and inversion of the guided waves for formation acoustic property estimation. This study introduces an equivalent-tool theory that models the tool response using an elastic rod with an effective modulus and applies the theory to multipole acoustic logging for both wireline and logging while drilling (LWD) conditions. The theory can be derived by matching the tool’s acoustic impedance/conductance to that of the multipole acoustic wavefield around the tool, assuming that tool radius is small compared to wavelength. We have validated the effectiveness and accuracy of the theory using numerical modeling and its practicality using field data. In field data applications, one can calibrate the tool parameters by fitting the theoretical dispersion curve to field data without having to consider the actual tool’s structure and composition. We use a dispersion correction example to demonstrate an application of the simple theory to field data processing and the validity of the processing result. 展开更多
关键词 Equivalent theory acoustic tool modeling impedance match guided wave
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Exploring the Low-Temperature Oxidation Chemistry of Cyclohexane in a Jet-Stirred Reactor:an Experimental and Kinetic Modeling Study 被引量:3
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作者 Jia-biao Zou Wei Li +4 位作者 Li-li Ye Xiao-yuan Zhang Yu-yang Li Jiu-zhong Yang Fei Qi 《Chinese Journal of Chemical Physics》 SCIE CAS CSCD 2018年第4期537-546,615,共11页
We report the investigation on the low-temperature oxidation of cyclohexane in a jet-stirred reactor over 500-742 K. Synchrotron vacuum ultraviolet photoionization mass spectrometry (SVUV-PIMS) was used for identify... We report the investigation on the low-temperature oxidation of cyclohexane in a jet-stirred reactor over 500-742 K. Synchrotron vacuum ultraviolet photoionization mass spectrometry (SVUV-PIMS) was used for identifying and quantifying the oxidation species. Major products, cyclic olefins, and oxygenated products including reactive hydroperoxides and high oxygen compounds were detected. Compared with n-alkanes, a narrow low-temperature window (-80 K) was observed in the low-temperature oxidation of cyclohexane. Besides, a kinetic model for cyclohexane oxidation was developed based on the CNRS model [Combust. Flame 160, 2319 (2013)], which can better capture the experimental results than previous models. Based on the modeling analysis, the 1,5-H shift dominates the crucial isomerization steps of the first and second O2 addition products in the low-temperature chain branching process of cyclohexane. The negative temperature coefficient behavior of cyclohexane oxidation results from the reduced chain branching due to the competition from chain inhibition and propagation reactions, i.e. the reaction between cyclohexyl radical and O2 and the de- composition of cyclohexylperoxy radical, both producing cyclohexene and HO2 radical, as well as the decomposition of cyclohexylhydroperoxy radical producing hex-5-en-l-al and OH radical. 展开更多
关键词 CYCLOHEXANE Low-temperature oxidation Synchrotron vacuum ultravioletphotoionization mass spectrometry Kinetic rnodel Negative temperature coefficient behavior
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Inverted Simulations Demonstrating Strong Ecological Fallacies in Cohort Studies
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作者 Shankar Srinivasan 《Journal of Mathematics and System Science》 2018年第5期119-139,共21页
We start with a description of the statistical inferential framework and the duality between observed data and the true state of nature that underlies it. We demonstrate here that the usual testing of dueling hypothes... We start with a description of the statistical inferential framework and the duality between observed data and the true state of nature that underlies it. We demonstrate here that the usual testing of dueling hypotheses and the acceptance of one and the rejection of the other is a framework which can often be faulty when such inferences are applied to individual subjects. This follows from noting that the statistical inferential framework is predominantly based on conclusions drawn for aggregates and noting that what is true in the aggregate frequently does not hold for individuals, an ecological fallacy. Such a fallacy is usually seen as problematic when each data record represents aggregate statistics for counties or districts and not data for individuals. Here we demonstrate strong ecological fallacies even when using subject data. Inverted simulations, of trials rightly sized to detect meaningful differences, yielding a statistically significant p-value of 0.000001 (1 in a million) and associated with clinically meaningful differences between a hypothetical new therapy and a standard therapy, had a proportion of instances of subjects with standard therapy effect better than new therapy effects close to 30%. A ―winner take all‖ choice between two hypotheses may not be supported by statistically significant differences based on stochastic data. We also argue the incorrectness across many individuals of other summaries such as correlations, density estimates, standard deviations and predictions based on machine learning models. Despite artifacts we support the use of prospective clinical trials and careful unbiased model building as necessary first steps. In health care, high touch personalized care based on patient level data will remain relevant even as we adopt more high tech data-intensive personalized therapeutic strategies based on aggregates. 展开更多
关键词 Ecological fallacies P-VALUES cohort studies case-control studies inverted simulation hypothesis testing aggregate statistics publication bias correlation machine learning personalized care and therapy.
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