The exact solution of Sehrodinger equation corresponding to a baryonic system is the main interest in the present work. We take into account both quadratic and Coulomb terms in the potential relation. Next, after pres...The exact solution of Sehrodinger equation corresponding to a baryonic system is the main interest in the present work. We take into account both quadratic and Coulomb terms in the potential relation. Next, after presenting an exact solution, we have calculated the spin and isospin effects in both ground and excited states. The results are comparable with experimental data.展开更多
Berberine hydrochloride is commonly used to treat bacterial dysentery,gastroenteritis and other diseases.Many manufacturers are available on the market today,while the production process and formulation are quite diff...Berberine hydrochloride is commonly used to treat bacterial dysentery,gastroenteritis and other diseases.Many manufacturers are available on the market today,while the production process and formulation are quite different,which may directly affect the therapeutic effect of the drug.To this end,11 different production producers of berberine hydrochloride tablets were collected according to the pharmacopeia berberine hydrochloride dissolution method(basket method).In addition the dissolution process was carried out in four elution media with different pH,and the difference was similar(f2).Factors were calculated to evaluate in vitro dissolution requirements,and in vitro dissolution of different manufacturers of berberine hydrochloride tablets was determined by high performance liquid chromatography(HPLC).The method was verified by linearity,precision,stability and robustness.Based on the f2 value,there was a significant difference in the dissolution behavior of the formulations of most berberine hydrochloride tablet brands.This research provided the basis for further in-depth research in the later period.Although the drug specifications(0.1 g)were the same,the dissolution curve was different.This phenomenon may be attributed to the fact that the excipients and crystal form of the tablets affected the release and dissolution of the tablets in vitro.展开更多
This article presents a general form of the estimator for identifying dispersion effects from unreplicated two-level factorial experiments,and shows that the widely used estimators such as the BH,MH,and AMH estimators...This article presents a general form of the estimator for identifying dispersion effects from unreplicated two-level factorial experiments,and shows that the widely used estimators such as the BH,MH,and AMH estimators are all special cases of the proposed one,designated as the G estimator.The unbiased condition of the G estimator is proved,and a lower bound of variance of the G estimator is provided.A simulation based on a realistic design illustrates the variation of the variance and MSE(mean square error) of the G estimator on different coefficients.This estimator may be more flexible and has better performance than other methods such as the BH and MH estimators by appropriately selecting the coefficients.展开更多
文摘The exact solution of Sehrodinger equation corresponding to a baryonic system is the main interest in the present work. We take into account both quadratic and Coulomb terms in the potential relation. Next, after presenting an exact solution, we have calculated the spin and isospin effects in both ground and excited states. The results are comparable with experimental data.
基金National Institutes for Food and Drug Control(Grant No.017ZX09101001).
文摘Berberine hydrochloride is commonly used to treat bacterial dysentery,gastroenteritis and other diseases.Many manufacturers are available on the market today,while the production process and formulation are quite different,which may directly affect the therapeutic effect of the drug.To this end,11 different production producers of berberine hydrochloride tablets were collected according to the pharmacopeia berberine hydrochloride dissolution method(basket method).In addition the dissolution process was carried out in four elution media with different pH,and the difference was similar(f2).Factors were calculated to evaluate in vitro dissolution requirements,and in vitro dissolution of different manufacturers of berberine hydrochloride tablets was determined by high performance liquid chromatography(HPLC).The method was verified by linearity,precision,stability and robustness.Based on the f2 value,there was a significant difference in the dissolution behavior of the formulations of most berberine hydrochloride tablet brands.This research provided the basis for further in-depth research in the later period.Although the drug specifications(0.1 g)were the same,the dissolution curve was different.This phenomenon may be attributed to the fact that the excipients and crystal form of the tablets affected the release and dissolution of the tablets in vitro.
基金the National Natural Science Foundation of China(Nos.51709240 and 51579144)the High-Tech Ship Research Project Supported by Ministry of Industry and Information Technology(No.K24352)the Equipment Pre-research Project(No.41407010202)
基金supported by the National Natural Science Fund of China under Grant No.61503228Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi under Grant No.2015106
文摘This article presents a general form of the estimator for identifying dispersion effects from unreplicated two-level factorial experiments,and shows that the widely used estimators such as the BH,MH,and AMH estimators are all special cases of the proposed one,designated as the G estimator.The unbiased condition of the G estimator is proved,and a lower bound of variance of the G estimator is provided.A simulation based on a realistic design illustrates the variation of the variance and MSE(mean square error) of the G estimator on different coefficients.This estimator may be more flexible and has better performance than other methods such as the BH and MH estimators by appropriately selecting the coefficients.
