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基于脑肠轴理论概述中医药防治缺血性中风的研究 被引量:4
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作者 王馨扬 黄洁 +2 位作者 何宏盾 陈霞 祝美珍 《中医临床研究》 2022年第24期16-20,共5页
缺血性中风是指多种原因引起脑部血液供应障碍导致脑组织不可逆的损伤,近年来其患病率持续上升,严重危害人类的健康和生活质量。近年来研究发现缺血性中风的发生发展与脑肠轴的异常变化相关,脑肠轴在脑系疾病的防治研究中的作用逐步受... 缺血性中风是指多种原因引起脑部血液供应障碍导致脑组织不可逆的损伤,近年来其患病率持续上升,严重危害人类的健康和生活质量。近年来研究发现缺血性中风的发生发展与脑肠轴的异常变化相关,脑肠轴在脑系疾病的防治研究中的作用逐步受到重视。文章通过对脑肠轴通路中各个调控环节的研究现状、脑肠轴理论与中医理论二者之契合点以及中医药对缺血性中风防治的临床实验研究进行论述。当前中医药对脑缺血防治已取得很好的疗效,目前研究发现中药组方、中药单体、中药有效成分份和针灸治疗能有效调控脑肠轴通路,介导脑肠肽和下丘脑-垂体-肾上腺轴(HPA)的调节,有效维持肠道微生物群的生态平衡和保护脑肠屏障,从而对缺血性中风后的神经缺损、胃肠功能障碍具有良好的保护作用,并能减轻脑梗死体积、改善脑功能。中医认为脾胃失调,酝酿痰瘀,痰瘀互结而气血运行不畅是中风的病机,从藏象学说、经络走行、经方等多个角度均认为脑和胃肠之间存在相关通路,中风发生时改善胃肠脏腑气机升降以达醒神通窍之效,这也遵循上病下治的治则,符合脑肠轴理论。脑肠轴理论和中医理论二者结合为将来脑缺血的治疗方案研究提供有效的方向和理论参考。现将研究现况综述如下。 展开更多
关键词 脑肠轴 中医药 缺血性中风 科技期刊 数学化转型
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Mathematical models and expert system for grate-kiln process of iron ore oxide pellet production.Part Ⅱ:Rotary kiln process control 被引量:7
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作者 范晓慧 王祎 陈许玲 《Journal of Central South University》 SCIE EI CAS 2012年第6期1724-1727,共4页
Rotary kiln process for iron ore oxide pellet production is hard to detect and control.Construction of one-dimensional model of temperature field in rotary kiln was described.And the results lay a solid foundation for... Rotary kiln process for iron ore oxide pellet production is hard to detect and control.Construction of one-dimensional model of temperature field in rotary kiln was described.And the results lay a solid foundation for online control.Establishment of kiln process control expert system was presented,with maximum temperature of pellet and gas temperature at the feed end as control cores,and interval estimate as control strategy.Software was developed and put into application in a pellet plant.The results show that control guidance of this system is accurate and effective.After production application for nearly one year,the compressive strength and first grade rate of pellet are increased by 86 N and 2.54%,respectively,while FeO content is 0.05% lowered.This system can reveal detailed information of real time kiln process,and provide a powerful tool for online control of pellet production. 展开更多
关键词 mathematical model expert system one-dimensional temperature field rotary kiln iron ore oxide pellet
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A Mathematical Model of Renal Blood Distribution Coupling TGF,MR and Tubular System
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作者 GAO Ci-xiu YANG Lin +2 位作者 WANG Ke-qiang XU Shi-xiong DAI Pei-dong 《Chinese Journal of Biomedical Engineering(English Edition)》 2009年第1期9-20,共12页
Objective:To investigate the relationship between renal blood distribution and the physiological activities of the kidney. Methods:A mathematical model is developed based on response (MR) Hagan-Poiseuille law and ... Objective:To investigate the relationship between renal blood distribution and the physiological activities of the kidney. Methods:A mathematical model is developed based on response (MR) Hagan-Poiseuille law and mass transport, coupling mechanics of myogenic tubuloglomerular feedback (TGF) and the tubular system in the renal medulla. The model parameters, including the permeability coefficients, the vascular lumen radius and the solute concentration at the inlet of the tubes, are derived from the experimental results. Simulations of the blood and water flow in the loop of Henel, the collecting duct and vas rectum, are carried out by the model of the tubular system in the renal medulla, based on conservations of water and solutes for transmural transport. Then the tubular model is coupled with MR and TGF mechanics. Results:The results predict the dynamics of renal autoregulation on its blood pressure and flow, and the distributions are 88.5% in the cortex, 10.3% in the medulla, and 1.2% at papilla,respectively. The fluid flow and solute concentrations along the tubules and vasa recta are obtained. Conclusion :The present model could assess renal functions qualitatively and quantitatively and provide a methodological approach for clinical research. 展开更多
关键词 renal blood distribution mathematical modeling myogenic response MR tubuloglomerular feedback (TGF)
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SPECIAL ISSUE: ONLINE LITERATURE IN CHINA: PRESENT SITUATION AND THEORETICAL REFLECTIONS Chinese Literature's Transformation and Digital Existence in the New Century 被引量:1
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作者 Ouyang Youquan 《Social Sciences in China》 2011年第1期146-165,共20页
The reform ignited by digital media provided strong impetus to literary transformation at the turn of century in China. The market-led rise of online literature has destroyed the balance of traditional literature and ... The reform ignited by digital media provided strong impetus to literary transformation at the turn of century in China. The market-led rise of online literature has destroyed the balance of traditional literature and resulted in a fundamental digital readjustment of the overall literary structure. The fourth medium, with its irresistible technological force, has led to a large-scale literary shift towards "being digital," thereby changing literary traditions of existence and expression. Such being the case, we need to clarify digital media's dual function of"deconstruction" and "construction" in this literary shift so as to input new ideas from a different academic perspective into literary theory of the digital era, turn digital media's challenge to tradition into a chance for literary innovation and make the new media into a powerful driving force and effective resource for Chinese literature in the new century. 展开更多
关键词 Chinese literature turn-of-the-century transformation being digital
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