Objective： The aim of our study was to compare the risk of main postoperative complications of patients un- derwent total thyroidectomy （TT）, near total thyroidectomy （NTT） and subtotal thyroidectomy （ST） for t...Objective： The aim of our study was to compare the risk of main postoperative complications of patients un- derwent total thyroidectomy （TT）, near total thyroidectomy （NTT） and subtotal thyroidectomy （ST） for treating BMNG. Methods： Electronic databases including Cochrane Controlled Trials Register, EMbase, Medline, SCI Expanded-ISI, NTIS, SIGLE and CNKI were searched. Eligible studies were randomized controlled trials which compared the incidence of postoperative complications of TT with ST/NTT for treating BMNG. Data extraction was using predefined data fields and assessment of methodological quality with the GRADE approach. A ManteI-Haenszel random-effects model was used and the effect sizes were expressed by using relative risks and 95% confidence intervals. Results： Four studies including 881 participants that met inclusion criteria were analyzed. Compared with ST/NTT, TT was associated with increased risk of transient RLNI （recur- rent laryngeal nerve injuries） （relative risk 2.18, 95% confidence interval 1.08 to 4.42; P 〈 0.05） and transient hypocalcemia （3.79, 1.64 to 8.77; P 〈 0.05）, but there were no statistically significant differences in permanent RLNI （1.36, 0.31 to 6.02; P 〉 0.05） and permanent hypocalcemia （2.37, 0.35 to 15.97; P 〉 0.05）. The quality of evidence for each individual outcome was ultimately rated as moderate （permanent RLNI and permanent hypocalcemia）, low （transient RLNI and transient hypocalce- mia）. Conclusion： For treating BMNG with thyroidectomy, there were no statistically significant differences in postoperative complications between TT and ST/NTT on a long view.展开更多
We investigated the clinical features of soft-tissue recurrence in giant cell tumor of bone （GCTB）. Among 106 cases with GCTB in our hospital, there were 2 cases occurring soft-tissue recurrence which histories were...We investigated the clinical features of soft-tissue recurrence in giant cell tumor of bone （GCTB）. Among 106 cases with GCTB in our hospital, there were 2 cases occurring soft-tissue recurrence which histories were reported. These two soft-tissue recurrences occurred with the interval of 6.9 years and 2.5 years respectively from pdmary diagnosis. The clinical presentation was nonspecific masses in soft tissue. Radiographic ossification was not found at periphery or within the masses. Through pathological examination peripheral ossification was found in 1 case and malignant transformation occurred in the other case. Through retrieving and reviewing literatures in PubMed, 19 cases of soft-tissue recurrence with detailed materials were collected and analyzed. Soft-tissue recurrence of GCTB is a rare episode which reflects its locally aggressive nature, the reasons of which are tumor cells implantation and tumor residual. Ossification at periphery or in the masses can be considered as a pathognomonic character of this episode in radiographic and pathohistological examination. The prevention lies in determining tumor extension preoperatively, proper non-tumor manipulations, removing the tumor and irrigating operative wound as completely as possible.展开更多
文摘Objective： The aim of our study was to compare the risk of main postoperative complications of patients un- derwent total thyroidectomy （TT）, near total thyroidectomy （NTT） and subtotal thyroidectomy （ST） for treating BMNG. Methods： Electronic databases including Cochrane Controlled Trials Register, EMbase, Medline, SCI Expanded-ISI, NTIS, SIGLE and CNKI were searched. Eligible studies were randomized controlled trials which compared the incidence of postoperative complications of TT with ST/NTT for treating BMNG. Data extraction was using predefined data fields and assessment of methodological quality with the GRADE approach. A ManteI-Haenszel random-effects model was used and the effect sizes were expressed by using relative risks and 95% confidence intervals. Results： Four studies including 881 participants that met inclusion criteria were analyzed. Compared with ST/NTT, TT was associated with increased risk of transient RLNI （recur- rent laryngeal nerve injuries） （relative risk 2.18, 95% confidence interval 1.08 to 4.42; P 〈 0.05） and transient hypocalcemia （3.79, 1.64 to 8.77; P 〈 0.05）, but there were no statistically significant differences in permanent RLNI （1.36, 0.31 to 6.02; P 〉 0.05） and permanent hypocalcemia （2.37, 0.35 to 15.97; P 〉 0.05）. The quality of evidence for each individual outcome was ultimately rated as moderate （permanent RLNI and permanent hypocalcemia）, low （transient RLNI and transient hypocalce- mia）. Conclusion： For treating BMNG with thyroidectomy, there were no statistically significant differences in postoperative complications between TT and ST/NTT on a long view.
文摘We investigated the clinical features of soft-tissue recurrence in giant cell tumor of bone （GCTB）. Among 106 cases with GCTB in our hospital, there were 2 cases occurring soft-tissue recurrence which histories were reported. These two soft-tissue recurrences occurred with the interval of 6.9 years and 2.5 years respectively from pdmary diagnosis. The clinical presentation was nonspecific masses in soft tissue. Radiographic ossification was not found at periphery or within the masses. Through pathological examination peripheral ossification was found in 1 case and malignant transformation occurred in the other case. Through retrieving and reviewing literatures in PubMed, 19 cases of soft-tissue recurrence with detailed materials were collected and analyzed. Soft-tissue recurrence of GCTB is a rare episode which reflects its locally aggressive nature, the reasons of which are tumor cells implantation and tumor residual. Ossification at periphery or in the masses can be considered as a pathognomonic character of this episode in radiographic and pathohistological examination. The prevention lies in determining tumor extension preoperatively, proper non-tumor manipulations, removing the tumor and irrigating operative wound as completely as possible.
