基于文献挖据的脑分水岭梗死中医证候要素研究

目的通过对文献的系统梳理,汇总脑分水岭梗死的证候类型,提炼分水岭梗死的证候要素,为该病临床证候研究提供标准化依据。方法在中国学术期刊全文数据库(CNKI)、万方数据资源系统(Wanfang Database)、中国生物医学文献数据库(CBM)上检索与脑分水岭梗死中医证候相关的文献,对证候及证候要素进行频数、频率的统计。结果通过文献挖掘,最后确定了脑分水岭梗死病性要素为:风、湿、火、内风、内湿、内火、气虚、血虚、气脱、血瘀、阴虚、阳亢、痰、气逆,共计14个,而病位要素责之心脑,与肝肾关系密切。结论通过证候要素提取及应证组合研究,对下一步研究规范脑分水岭梗死中医辨证分型及命名提供参考和依据。

Commonality and pattern analysis of acupoint selection in moxibustion treatment of asthma

Objective:To analyze and summarize the commonalities and patter ns in acupoi nt selectio n for moxibustio n treatme nt of asthma.Methods:Data retrieval was conducted using'moxibustion'and'asthma'as the keywords through China National Knowledge Infrastructure(CNKI),Wanfang Academic Journal Full-text Database(Wanfang)and Chongqing VIP Database(CQVIP).Excel 2010 was used to establish the major acupoint database for moxibustion prescript!ons in treatment of asthma;data mining methods in cludi ng associati on patter ns and clusteri ng were adopted to an a lyze the characteristics and patter ns in acupoi nt selecti on for moxibusti on treatment of asthma.Results:A total of 161 moxibustion prescriptions were recruited.The most commonly used acupoint was Feishu(BL 13),the most commonly used meridian was the Bladder Meridian of Foot Taiyang,and the most commonly treated region was the back.The association rule analysis showed that Feishu(BL 13)-Dazhui(GV 14)-Fengmen(BL 12)had the most significant correlation,and the clustering analysis discovered 5 effective acupoint clusters.Conclusion:In moxibustion treatment of asthma,topical acupoints Feishu(BL 13),Dazhui(GV 14)and Fengmen(BL 12)can be selected,along with the acupoints from the Bladder Meridian of Foot Taiyang and the back.

Exploration on acupoint-selection patterns based on data mining for the treatment of chronic atrophic gastritis

Objective:To analyze the features and patterns of acupoint selection in acupuncture-moxibustion treatment of chronic atrophic gastritis(CAG)by data mining technique.Methods:Relevant clinical studies published before 25 June,2017 were searched in databases including PubMed,EMBASE,Cochrane library,Chinese Biomedical Literature Database(CBM),China National Knowledge infrastructure(CNKI),and Wanfang Academic Journal Full-text Database(Wanfang).Results:A total of 122 papers were included,involving 69 points.It was found that the top three points on the frequency list were Zusanli(ST 36),Zhongwan(CV 12)and Weishu(BL 21).The points selected were distributed in 11 meridians,in which the Stomach Meridian of Foot Yangming,Conception Vessel,and Bladder Meridian of Foot Taiyang ranked the top and accounted for 74.0%of the total frequency.Of the involved specific points,Five Shu-Transmitting points,crossing points and Back-Shu points ranked the top,accounting for 47.1%.The analysis of association pattern has shown that Zusanli(ST 36)and Zhongwan(CV 12)won the highest support rate in the paired groups;Zusanli(ST 36),Weishu(BL 21)and Zhongwan(CV 12)had the highest support rate among the point groups.The Five Shu-Transmitting points and the Lower He-Sea points had the highest support rate among the specific point groups.Conclusion:The data mining results of the studies on acupuncture-moxibustion for CAG are substantially in line with the acupuncture-moxibustion treatment theories in traditional Chinese medicine.The results can reflect the acupoint selection patterns in treatment of CAG and provide reference for acupuncture-moxibustion treatment of CAG in clinic.

Analysis of acupoint-selection patterns in acupuncture-moxibustion treatment of polycystic ovarian syndrome based on data mining

Objective:To analyze the meridian and acupoint-selection patterns in acupuncture-moxibustion treatment of polycystic ovarian syndrome (PCOS) by data mining technique,for exploring acupoints that could be effective for PCOS and providing suggestion and reference in selecting acupoints for the acupuncture-moxibustion treatment of PCOS.Methods:Literatures related to the acupuncture-moxibustion treatment of PCOS published before April 2018 were collected.By a self-made data mining program developed using Microsoft Excel 2007,a database of acupuncture-moxibustion treatment of PCOS was then established.The correlation analysis was performed for the frequency of use of acupoints and acupoint groups.Cluster analysis was also conducted.Results:A total of 92 articles were recruited finally.Sanyinjiao (SP 6),Conception Vessel and chest-abdomen region ranked the top on the list of the most frequently used acupoints,meridians and regions,respectively.Correlation analysis showed that the acupoint group with the highest confidence was Sanyinjiao (SP 6) and Zusanli (ST 36),and the group with the highest support was Sanyinjiao (SP 6) and Guanyuan (CV 4).Cluster analysis revealed five effective clusters:Guanyuan (CV 4) and Sanyinjiao (SP 6);Zhongwan (CV 12) and Tianshu (ST 25);Zhongji (CV 3),Zusanli (ST 36) and Qihai (CV 6);Xuehai (SP 10),Shenshu (BL 23),Taichong (LR 3) and Guilai (ST 29);Ganshu (BL 18),Taixi (KI 3),Yinlingquan (SP 9) and Pishu (BL 20).Conclusion:According to the confidence and support report,Sanyinjiao (SP 6) and Zusanli (ST 36) or Sanyinjiao (SP 6) and Guanyuan (CV 4) are recommended in acupuncture-moxibustion treatment of PCOS,with adjunct points selected for different patterns,e.g.Zhongwan (CV 12) and Tianshu (ST 25) for tonifying spleen and expelling dampness;Zhongji (CV 3) and Qihai (CV 6) for supplementing qi and cultivating blood;Xuehai (SP 10),Shenshu (BL 23),Taichong (LR 3) and Guilai (ST 29) for tonifying kidney and dissolving stasis;Ganshu (BL 18),Taixi (KI 3),Yinlingquan (SP 9) and Pishu (BL 20) for tonifying kidney and spleen and regulating liver.

Clinical application of the second metacarpal bone lateral needling

Objective： To explore the rules of the second metacarpal bone lateral needling in clinical application and its characteristics so as to provide the guidance to clinical practice.Methods： Taking ＂the second metacarpal holographic acupuncture therapy＂ ＂the second metacarpal bone lateral needling＂ and ＂the second metacarpal bone＂ as the search terms, the papers on the second metacarpal bone lateral needling were retrieved from China National Knowledge Infrastructure（CNKI）and Wanfang database from January 1, 1974 to December 31, 2016 and were screened. Using the Excel2003, the database of the diseases treated by the second metacarpal bone lateral needling was set up.The indications, the acupoints selection rules and needling manipulation of this therapy were analyzed.Results： A total of 1103 papers were retrieved, of which, 446 papers were from CNKI and 657 from Wanfang database. According to the inclusion and exclusion criteria, 54 papers were included for analysis finally. It was found that the indications of the second metacarpal bone lateral needling were predominated by the soft tissue injuries, especially acute lumbar sprain, ankle sprain and knee joint injury. Regarding the acupoints selection rules of the second metacarpal bone lateral needling, the corresponding points and tender points were commonly selected. Regarding the needling manipulation, the strong stimulation was required after needle insertion and the patient was required to move the affected areas while keeping the strong needling sensation. The needles were inserted 20 mm in depth along the skin mainly.The even-needling technique was exerted and the needles were retained for 30 min mainly.Conclusion： The second metacarpal bone lateral needling is applied to the treatment of soft tissue injuries. It is applicable for some internal diseases. The strong needling sensation and the motion of the local affected area are required especially in treatment with this therapy.