8头颈癌患者放化疗和放疗后的感觉神经性耳聋：文献系统评价
Sensorineural hearing loss in patients with head and neck cancer after chemoradiotherapy and radiotherapy： A systematic review of the literature. Theunissen E...8头颈癌患者放化疗和放疗后的感觉神经性耳聋：文献系统评价
Sensorineural hearing loss in patients with head and neck cancer after chemoradiotherapy and radiotherapy： A systematic review of the literature. Theunissen EA,Bosma SC,Zuur CL,et al. Head Neck, 2013 Nov 7.
头颈癌患者放疗（RT）和以顺铂为主的放化疗（CRT）可以引起感觉神经性耳聋fSNHL）。该文旨在回顾CRT与RT引起的SNHL，并作进一步探究。以“放疗”，“耳毒性”，“头颈鳞癌”及其同义词为关键词，在Medline和Embase进行检索。展开更多
目的：评价在中高危息龋风险患者中使用氯己定漱口液中减少致龋菌的有效性。材料与方法：利用Cochrane Library、Embase、PubMed、Scopus和Web of Science完成文献系统评价。检索截止到2017年1月发表的英语、西班牙语和葡萄牙语文章。根...目的：评价在中高危息龋风险患者中使用氯己定漱口液中减少致龋菌的有效性。材料与方法：利用Cochrane Library、Embase、PubMed、Scopus和Web of Science完成文献系统评价。检索截止到2017年1月发表的英语、西班牙语和葡萄牙语文章。根据PICO策略设计检索问题。利用Cochrane干预系统评价手册的指南做偏倚风险评估。结论：所有作者都发现了在使用氯己定漱口液过程中及之后，变异链球菌水平有统计上的显著差异。尽管这些结果有启发性,但是仍有必要开展新的高质量长随访周期的研究以评估这些结果能否转化用于减缓龋齿的发展，从而评估这些产品是否应纳入防龋方案。展开更多
In Pakistan more than 10 million people are living with Hepatitis C virus (HCV), with high morbidity and mortality. This article reviews the prevalence, genotypes and factors associated with HCV infection in the Pakis...In Pakistan more than 10 million people are living with Hepatitis C virus (HCV), with high morbidity and mortality. This article reviews the prevalence, genotypes and factors associated with HCV infection in the Pakistani population. A literature search was performed by using the keywords; HCV prevalence, genotypes and risk factors in a Pakistani population, in Pubmed, PakMediNet and Google scholar. Ninetyone different studies dating from 1994 to May 2009 were included in this study, and weighted mean and standard error of each population group was calculated. Percentage prevalence of HCV was 4.95% ± 0.53% in the general adult population, 1.72% ± 0.24% in the pediatric population and 3.64% ± 0.31% in a young population applying for recruitment, whereas a very high 57% ± 17.7% prevalence was observed in injecting drug users and 48.67% ± 1.75% in a multi-transfused population. Most prevalent genotype of HCV was 3a. HCV prevalence was moderate in the general population but very high in injecting drug users and multi-transfused populations. This data suggests that the major contributing factors towards increased HCV prevalence include unchecked blood transfusions and reuse of injection syringes. Awareness programs are required to decrease the future burden of HCV in the Pakistani population.展开更多
文摘8头颈癌患者放化疗和放疗后的感觉神经性耳聋：文献系统评价
Sensorineural hearing loss in patients with head and neck cancer after chemoradiotherapy and radiotherapy： A systematic review of the literature. Theunissen EA,Bosma SC,Zuur CL,et al. Head Neck, 2013 Nov 7.
头颈癌患者放疗（RT）和以顺铂为主的放化疗（CRT）可以引起感觉神经性耳聋fSNHL）。该文旨在回顾CRT与RT引起的SNHL，并作进一步探究。以“放疗”，“耳毒性”，“头颈鳞癌”及其同义词为关键词，在Medline和Embase进行检索。
文摘目的：评价在中高危息龋风险患者中使用氯己定漱口液中减少致龋菌的有效性。材料与方法：利用Cochrane Library、Embase、PubMed、Scopus和Web of Science完成文献系统评价。检索截止到2017年1月发表的英语、西班牙语和葡萄牙语文章。根据PICO策略设计检索问题。利用Cochrane干预系统评价手册的指南做偏倚风险评估。结论：所有作者都发现了在使用氯己定漱口液过程中及之后，变异链球菌水平有统计上的显著差异。尽管这些结果有启发性,但是仍有必要开展新的高质量长随访周期的研究以评估这些结果能否转化用于减缓龋齿的发展，从而评估这些产品是否应纳入防龋方案。
基金Supported by Higher Education Commission of Pakistan Grant No.829Pak-US Science and Technology Cooperative Program,entitled "HCV management in Pakistan"
文摘In Pakistan more than 10 million people are living with Hepatitis C virus (HCV), with high morbidity and mortality. This article reviews the prevalence, genotypes and factors associated with HCV infection in the Pakistani population. A literature search was performed by using the keywords; HCV prevalence, genotypes and risk factors in a Pakistani population, in Pubmed, PakMediNet and Google scholar. Ninetyone different studies dating from 1994 to May 2009 were included in this study, and weighted mean and standard error of each population group was calculated. Percentage prevalence of HCV was 4.95% ± 0.53% in the general adult population, 1.72% ± 0.24% in the pediatric population and 3.64% ± 0.31% in a young population applying for recruitment, whereas a very high 57% ± 17.7% prevalence was observed in injecting drug users and 48.67% ± 1.75% in a multi-transfused population. Most prevalent genotype of HCV was 3a. HCV prevalence was moderate in the general population but very high in injecting drug users and multi-transfused populations. This data suggests that the major contributing factors towards increased HCV prevalence include unchecked blood transfusions and reuse of injection syringes. Awareness programs are required to decrease the future burden of HCV in the Pakistani population.
