识清假劣药面目斩断制售黑手

2008年，北京市药品监督管理局查处了一系列的重大案件，其中包括6．3瑞龙专案、6．11非法销售A型肉毒毒素案等轰动全国的重大、特大制假、售假案。全年共捣毁制假售假窝点20个，查扣假药品种121种，没收假药及用于制假的原料百余吨，用于制假的设备工具百余件，扣押用于从事制假售假的车辆12台，

腈纶拉断制条绕毛现象的探讨

本文对腈纶拉断制条过程中出现的绕毛现象进行了分类分析,总结出解决绕毛方法,可较大程度地提高生产效率。

化纤丝束的拉断法直接制条

聚丙烯睛纤维市场广泛分布于世界各地,过去的几十年中,生产国与消费国都发生了变化.纤维束的制造工艺已改善,同时,就其技术而言,牵切、再割、混合和前纺已逐渐进步,并且影响纤维的性能.

走“委办”妙棋 闯“买断”新路

江西省宜黄县电信局有员工53人,下辖14个电信所(其中代办所9个)、3个代办点,担负着全县12个乡镇、23万人的通信任务.由于该县地处革命老区,是个经济欠发达的山区小县,一定程度上制约了通信发展.此外,在计划经济体制和"官商"作风的影响下,农村分支机构管理中也存在不少问题:如思想观念陈旧,习惯于吃"大锅饭",部分员工中存在"吃拿卡要"等不良行为;监督不力,疏于管理,公话私收、损公肥私等情况时有发生,导致账款不清、欠费较多,造成企业收入流失;因机线维修不及时,多收、错收话费引发的用户申告不断等.

因企制宜 稳妥推进——盐城港口集团改制的作法

盐城港口集团是集装卸搬运、汽车货运、交通工业和商贸等业的综合体,所属中小企业达20多个。 去年以来,他们抱定“三个有利于”的宗旨,坚持从本港实际出发,对所属单位分别进行改制,整个集团出现了新的生机与活力。 为了稳步推进企业改制,做到有领导、有计划、有步骤地实施,集团成立企业改制领导小组。

地黄的保健作用

地黄的保健作用邵文杰，李顺发河南中医学院（４５０００３）邵巍河南中医学院二附院（４５０００２）主题词地黄／治疗应用，炮制地黄为常用中药，以产于河南的怀地黄为佳；最早的《诗经》就记载有地黄。《神农本草经》列为上品，谓其有补养健身之功。宋代《本草图经》首...

Bending properties and fracture mechanism of C/C composites with high density preform

C/C composites with banded structure pyrocarbon were fabricated by fast chemical vapor infiltration（CVI）,with C3H6 as carbon source,N2 as carrier gas,and three-dimensional（3D） 12K PAN-based carbon fabric with high density of 0.94 g/cm3 as preform.Experimental results indicated that the fracture characteristics of C/C composites were closely related to the frequency of high-temperature treatment（HTT） at the break of CVI process.According to the load？displacement curves,C/C composites showed a pseudoplastic fracture after twice of HTT.After three times of HTT,load？displacement curves tended to be stable with a decreasing bending strength at 177.5 MPa.Delamination failure and intrastratal fiber fracture were observed at the cross-section of C/C composites by scanning electronic microscope.Because the content of pyrocarbon and fibers has a different distribution in layers,the C/C composites show different fracture characteristics at various regions,which leads to good toughness and bending strength.

Study on Application of Microbial Ecological Agents, Replacements for Antibiotics, in Weaned Piglet Production

In order to investigate the appIication effects of microbial ecoIogical agents as repIacements for antibiotics in weaned pigIets, a total of 120 28 d oId healthy Duroc ＆#215;Landrace ＆#215;Large White weaned pigIets with simiIar bogy weights and body fats and cIose birth dates were seIected. They were randomIy divided into three groups, incIuding controI group （CK）, antibiotic group （A） and microbial ecoIogical agent group （MEA）. The growth performance, health status and economic benefits of the weaned pigIets were measured. The resuIts showed that the A and MEA groups couId better enhance the immunity of weaned pigIets and improve the economic benefits in the whoIe experimental period compared to the CK group （P〈0.01）. How-ever, there were no significant differences in pigIet immunity and economic benefits between the A and MEA groups （P〉0.05）. It is indicated that the Rujunbao, a mi-crobial ecoIogical agent, can be promoted in weaned pigIet production as a repIace-ment for antibiotic.

Fracture suppression at steel/concrete connection zones by ECC

In order to avoid brittle fracture failure, a ductile engineered cementitious composite （ECC） was attempted in steel/concrete connection zones to replace normal concrete. The influence of the ECC material ductility on connection failure modes and structural performance was investigated via the pushout test of stud/ECC connection, the pullout test of two-dimensional anchor bolt/ECC connection and the finite element modeling （FEM）. The experimental results suggest that the micromechanically designed ECC with a tensile ductility 300 times that of normal concrete switches the brittle fracture failure mode to a ductile one in steel connection zones. This modification in material behavior leads to higher load carrying capacity and structural ductility, which is also confirmed in FEM investigation. The enhancement in structural response through material ductility engineering is expected to be applicable to a wide range of engineering structures where steel and concrete come into contact.

AN INTRODUCTION TO NEW MULTIVARIATE DIAGNOSIS THEORY WITH TWO KINDS OF QUALITY AND ITS APPLICATIONS

In factory operations, the multi operation and multi index system is very common. In such a system, if we want to implement the quality control and diagnosis, we must consider the following two points, i.e. the influence on the preceding operation to the succeeding operation and the correlation among indices. Since these two points exist simultaneously, it makes the problem more complex. We need to use the new multivariate diagnosis theory with two kinds of quality proposed by Prof. Zhang Gongxu in 1996 to solve such complex problem. This paper presents its fundamental principles with practical applications which agree with the theory pretty well.

Plastic anisotropy and fracture behavior of AZ31 magnesium alloy

The effects of texture and abnormal large grains on the plastic anisotropy and fracture behavior of hot-rolled AZ31 magnesium alloy were investigated. Uniaxial tensile deformation behaviors of samples with tensile axis tilting 0°, 15°, 30°, 45°, 60°, 75° and 90° to normal direction （ND） respectively were addressed. Tensile deformation anisotropy was observed for samples with different angles to ND. The results show that the specimens with the angle from 0° to 30° exhibit relatively lower yielding strength due to the {1 012}extension twinning. However, basal slip and prismatic slip are the dominant deformation modes for the specimens with angles larger than 45°. Macro-fractures are parallel to the length direction of abnormal large grains in the specimens with angles less than 60°, while those are serrated fracture edge for specimens with angles 75° and 90°.

Application of Maximum Probability Approach to the Fault Diagnosis of a Servo System

In an actual control system, it is often difficult to find out where the faults are if only based on the outside fault phenomena, acquired frequently from a fault system. So the fault diagnosis by outside fault phenomena is considered. Based on the theory of fuzzy recognition and fault diagnosis, this method only depends on experience and statistical data to set up fuzzy query relationship between the outside phenomena (fault characters) and the fault sources (fault patterns). From this relationship the most probable fault sources can be obtained, to attain the goal of quick diagnosis. Based on the above approach, the standard fuzzy relationship matrix is stored in the computer as a system database. And experiment data are given to show the fault diagnosis results. The important parameters can be on line sampled and analyzed, and when faults occur, faults can be found, the alarm is given and the controller output is regulated.

ROBUST FAULT DIAGNOSIS FOR HELICOPTER FCS BASED ON LINEAR PARAMETERVARYING ADAPTIVE OBSERVER

Based on the linear parameter-varying （LPV） adaptive observer, the robust fault diagnosis for a class of LPV systems with external disturbances is studied. Since the flight control system （FCS） is nonlinear and time-varying, the LPV technique is used for FCS. And then the adaptive fault estimation algorithm based on the LPV adaptive observer is proposed to estimate the fault. To minimize the effect of disturbances on the fault estimation, the H~ robust performance index is introduced to design the LPV adaptive fault diagnosis observer and the fault estimation algorithm. The result shows that the method has good estimation performance and is robust to external disturbances. The design method is presented in terms of linear matrix inequalities （LMIs）. Finally, a helicopter LPV FCS model with the actuator fault is used to illustrate the effectiveness of the proposed method.

Knowledge Discovery in Maintenance Record of FMS Equipment for Diagnosing

To discover the knowledge of fault diagnosis in maintenance record of flexible manufacture system(FMS) equipment. An algorithm (process) was presented, which consists of ① preparatory phase in which some items in maintenance record are selected and decomposed into associated concepts and attributes, and ② discovering and establishing process, in which some possible relationships between the concepts and attributes can be established and knowledge is formulated. The rich diagnosis knowledge in maintenance record was captured through applying the method. An application of the method to the diagnosis system for FMS equipment showed that the approach is correct and effective.

High temperature mechanical behavior of alumina dispersion strengthened copper alloy with high content of alumina

The microstructure and its effects on the high temperature mechanical behavior of Cu-2.7%Al_2O_3 （volume fraction） dispersion strengthened copper （ADSC） alloy were investigated. The results indicate that fine alumina particles are uniformly distributed in the copper matrix, while a few coarse ones are distributed on the grain boundaries. Tensile tests results show that Hall-Petch mechanism is the main contribution to the yield strength of ADSC alloy at room temperature. Its high temperature strength is attributed to the strong pinning effects of alumina particles on the grain and sub-grain boundaries with dislocations. The ultimate tensile strength can reach 237 MPa and the corresponding yield strength reaches 226 MPa at 700℃. Tensile fracture morphology indicates that the ADSC alloy shows brittleness at elevated temperatures. Creep tests results demonstrate that the steady state creep rates at 400 ℃ are lower than those at 700 ℃. The stress exponents at 400 ℃ and 700℃ are 7 and 5, respectively, and the creep strain rates of the ADSC alloy are controlled by dislocation core diffusion and lattice diffusion.

CT perfusion at early stage of hepatic diffuse disease

AIM: To determine the validity of the non-invasive method of CT perfusion (CTP) in rat model of hepatic diffuse disease. METHODS: Twenty-eight Wistar rats were divided into two groups. Liver diffuse lesions were induced by diethyln-itrosamine in 14 rats of test group. Rats in control group were bred with pure water. From the 1st to 12th wk after the test group was intervened, both groups were studied every week with CTP. CTP parameters of liver parenchyma in different periods and pathologic changes in two groups were compared and analyzed. RESULTS: The process of hepatic diffuse lesions in test groups was classified into three stages or periods according to the pathologic alterations, namely hepatitis, hepatic fibrosis, and cirrhosis. During this period, hepatic artery flow (HAF) of control group declined slightly, mean transit time (MTT), blood flow (BF) and volume (BV) increased, but there were no significant differences between different periods. In test group, HAF tended to increase gradually, MTT prolonged obviously, BV and BF decreased at the same time. The results of statistical analysis revealed that the difference in the HAF ratio of test group to control group was significant. The ratio of BV and BF in test group to control group in stage of hepatitis and hepatic cirrhosis, hepatic fibrosis and early stage of hepatic cirrhosis was significantly different, but there was no significant difference between hepatitis and hepatic fibrosis. The main pathological changes in stage of hepatitis were swelling of hepatic cells, while sinusoid capillarization and deposition of collagen aggravated gradually in the extravascular Disse's spaces in stage of fibrosis and early stage of cirrhosis. CONCLUSION: The technique could reflect some early changes of hepatic blood perfusion in rat with liver diffuse disease and is valuable for their early diagnosis.

Improvement of Electrical Performance of SOI-LIGBT by Resistive Field Plate

The electrical performance including breakdown voltage and turn-off speed of SOI-LIGBT is improved by incorporating a resistive field plate (RFP) and a p-MOSFET.The p-MOSFET is controlled by a signal detected from a point of the RFP.During the turning-off of the IGBT,the p-MOSFET is turned on,which provides a channel for the excessive carriers to flow out of the drift region and prevents the carriers from being injected into the drift region.At the same time,the electric field affected by the RFP makes the excessive carriers flow through a wider region,which almost eliminates the second phase of the turning-off of the SOI-LIGBT caused by the substrate bias.Faster turn-off speed is achieved by above two factors.During the on state of the IGBT,the p-MOSFET is off,which leads to an on-state performance like normal one.At least,the increase of the breakdown voltage for 25% and the decrease of the turn-off time for 65% can be achieved by this structure as can be verified by the numerical simulation results.

Effect of rapid cold stamping on fracture behavior of long strip S′phase in Al−Cu−Mg alloy

High-angle annular dark-field scanning transmission electron microscopy and selected area electron diffraction techniques were used to study the mechanism that underlies the influence of rapid cold-stamping deformation on the fracture behavior of the elongated nanoprecipitated phase in extruded Al−Cu−Mg alloy.Results show that the interface between the long strip-shaped S′phase and the aluminum matrix in the extruded Al−Cu−Mg alloy is flat and breaks during rapid cold-stamping deformation.The breaking mechanisms are distortion and brittle failure,redissolution,and necking.The breakage of the long strip S′phase increases the contact surface between the S′phase and the aluminum matrix and improves the interfacial distortion energy.This effect accounts for the higher free energy of the S′phase than that of the matrix and creates conditions for the redissolution of solute atoms back into the aluminum matrix.The brittle S′phase produces a resolved step during rapid cold-stamping deformation.This step further accelerates the diffusion of solute atoms and promotes the redissolution of the S′phase.Thus,the S′phase necks and separates,and the long strip-shaped S′phase in the extruded Al−Cu−Mg alloy is broken into a short and thin S′phase.

Numerical simulation on effect of heterogeneity on modeΙfracture characteristics of rock

Rock is more sensitive to tensile loading than compressive loading,since the tensile strength of rock is much lower than compressive strength.The fracture characteristics of rock in the tensile state are of great significance to the understanding of rock failure mechanisms.To this end,we have conducted numerical simulation researches on modeⅠcracking process of rock with varying homogeneity,using the Realistic Failure Process Analysis program.With the increase of homogeneity,cracks are concentrating to the ligament area with a decreasing number of crack bifurcations,and the main crack path is becoming smooth.Crack behaviors and mechanical properties are influenced significantly when the homogeneity index is in the range of 1.5 to 5.When the homogeneity index is greater than 30,they are not affected by rock homogeneity and the rock can be considered as essentially homogeneous.It is considered that the global and local strengths are affected by the distribution of rock mechanical properties at mesoscale,which influence the crack behaviors and mechanical characteristics.

Design and development of WLAN access point based on Bluetooth and uClinux

This paper describes the design and development of a wireless LAN (WLAN) access point based on Bluetooth and uClinux. To make the best use of high-speed serial communication capability, several methods such as modifying baud-rate of serial port driver, utilizing buffer area and adding flow-control were adopted. After analysis of scheduling and interruption handling, modifying the timer's parameters was put forward as a method to control the timer interrupt. In this way, data throughput and system stability were enhanced. Meanwhile, migration of the Bluetooth protocol stack was detailed and some successful applications of LAN access point were presented.