Olfactory ensheathing cells from the olfactory bulb and olfactory mucosa have been tbund to increase axonal sprouting and pathfinding and promote the recovery of vibrissae motor performance in facial nerve transection...Olfactory ensheathing cells from the olfactory bulb and olfactory mucosa have been tbund to increase axonal sprouting and pathfinding and promote the recovery of vibrissae motor performance in facial nerve transection injured rats. However, it is not yet clear whether olfactory ensheathing cells promote the reparation of facial nerve defects in rats. In this study, a collagen sponge and silicone tube neural conduit was implanted into the 6-mm defect of the buccal branch of the facial nerve in adult rats. Olfactory ensheathing cells isolated from the olfactory bulb of newborn Sprague-Dawley rats were injected into the neural conduits connecting the ends of tile broken nerves, the morphology and function of the regenerated nerves were compared between the rats implanted with olfactory ensheathing cells with the rats injected with saline. Facial paralysis was assessed. Nerve electrography was used to measure facial nerve-induced action potentials. Visual inspection, anatomical microscopy and hematoxylin-eosin staining were used to assess the histomorphology around the trans planted neural conduit and the morphology of the regenerated nerve. Using fluorogold retrograde tracing, toluidine blue staining and lead uranyl acetate staining, we also measured the number of neurons in the anterior exterior lateral f:acial nerve motor nucleus, the number of myelinated nerve fibers, and nerve fiber diameter and myelin sheath thickness, respectively. After surgery, olfactory ensheathing cells de- creased facial paralysis and the latency of the facial nerve-induced action potentials. There were no differences in the general morphology of the regenerating nerves between the rats implanted with olfactory ensheathing cells and the rats injected with saline. Between-group results showed that olfactory ensheathing cell treatment increased the number of regenerated neurons, improved nerve fiber morphology, and increased the number of myelinated nerve fibers, nerve fiber diameter, and myelin sheath thickness. In conclusion, implantation of olfactory ensheathing cells can promote regeneration and functional recovery after facial nerve damage in rats.展开更多
To improve the separation performance of a supersonic gas separation device for the treatment of gas mixture with a single heavy component, a novel structure with shorter settlement distance was constructed and a meth...To improve the separation performance of a supersonic gas separation device for the treatment of gas mixture with a single heavy component, a novel structure with shorter settlement distance was constructed and a method of droplet enlargement was applied. A series of experiments were carried out in the improved separation device under various conditions, using air-ethanol vapor as the medium and micro water droplets as nucleation cen- ters. The effects of the inlet pressure, temperature and relative humidity, the swirling intensity, and mass flow rate of water on the separation performance were investigated. The separation was improved by increasing the inlet pressure and relative humidity. With the decrease of swirling intensity and mass flow rate of water, the separation efficiency increased first and then decreased. The inlet temperature had a slight effect on the separation. The results showed that the separation performance was effectively improved using the proposed structure and method, and the best separation in this study was obtained with the ethanol removal rate about 55% and dew point depression 27 K. The addition of water had little pollution to the air-ethanol vapor system since the water carry-over rate was within the range of -2 %-0 in most cases.展开更多
The unsaturated undisturbed quaternary system middle pleistocene loess,a typical unsaturated soil,often occurs in the implementation of western development strategy.To obtain the shearing strength characteristics of t...The unsaturated undisturbed quaternary system middle pleistocene loess,a typical unsaturated soil,often occurs in the implementation of western development strategy.To obtain the shearing strength characteristics of this unsaturated undisturbed loess,based on the analysis of mineral composition,the triaxial shear test of undisturbed quaternary system middle pleistocene loess under different moisture contents is conducted with the specialized triaxial instrument for unsaturated soil.The test results show that the mainly mineral composition of undisturbed quaternary system middle pleistocene loess is quartz and albite.Under the same confining pressure,the matric suction increases with the decrease of moisture content.The smaller the moisture content,the larger the matric suction;the higher the moisture content,the lower the matric suction.Under the same moisture content,the matric suction increases with the confining pressure and reaches a maximum when the confining pressure is 100 kPa,and then decreases with the increase of confining pressure.This phenomenon is closely related to the grain contact tightness of soil mass under high confining pressure.According to the triaxial test of loess,the sample of loess experiences 4 stages from loading to failure:1) compaction stage;2) compression stage;3) microcrack developing stage;4) shear failure stage.The test sample is of brittle failure(weak softening)under low moisture content and confining pressure.With the decrease of matric suction and the increase of consolidated confining pressure,the stress-strain curve changes from softening type to ideal plastic type.In the shearing strength parameters of unsaturated undisturbed loess,the influence of moisture content on internal friction angle is small,but that on cohesive force is obvious.Therefore,the shearing strength of unsaturated undisturbed loess is higher than that of saturated undisturbed loess and varies with the moisture content.展开更多
Previous studies carried out in the East China Sea (ECS) mud area focused on long-term environmental changes in sedimentary records during the Holoeene, especially during the mid-Holocene high-stand water levels per...Previous studies carried out in the East China Sea (ECS) mud area focused on long-term environmental changes in sedimentary records during the Holoeene, especially during the mid-Holocene high-stand water levels period. These results indicate that sensitive grain size groups can be used as a sedimentary proxy to reconstruct the evolution of the East Asian Winter Monsoon (EAWM). The studies have been carried out mainly in the northern and middle portions of the Zhejiang-Fujian coastal mud, however, similar research in the southern portion and the comparison between sedimentary proxy and modern measured data of EAWM are lacking. In this paper, we focused on a sedimentary record of the past 100 years with an enhanced resolution of 1.8 years. Investigations of the southern end of the Zhejiang-Fujian coastal mud area were conducted on the basis of 21~Pb chronology, grain-size analysis and chemical element analysis. The correspondence between the mean grain size (Mz) of sediment sensitive grain size and the measured EAWM was confirmed for the first time. We found that during the recent 100 years, the variation of the mean grain size of the sensitive population in the southern portion of the Zhejiang-Fujian mud was mainly controlled by the EAWM intensity changes; and not directly related to changes in the sediment discharge from Datong station of the Changjiang River (DTSD). Finally, recent changes in the content of heavy metals in study area reflect the impact of human activities on the environment.展开更多
In order to establish the baseline finite element model for structural health monitoring,a new method of model updating was proposed after analyzing the uncertainties of measured data and the error of finite element m...In order to establish the baseline finite element model for structural health monitoring,a new method of model updating was proposed after analyzing the uncertainties of measured data and the error of finite element model.In the new method,the finite element model was replaced by the multi-output support vector regression machine(MSVR).The interval variables of the measured frequency were sampled by Latin hypercube sampling method.The samples of frequency were regarded as the inputs of the trained MSVR.The outputs of MSVR were the target values of design parameters.The steel structure of National Aquatic Center for Beijing Olympic Games was introduced as a case for finite element model updating.The results show that the proposed method can avoid solving the problem of complicated calculation.Both the estimated values and associated uncertainties of the structure parameters can be obtained by the method.The static and dynamic characteristics of the updated finite element model are in good agreement with the measured data.展开更多
With rapid development of PetroChina's Qinghai Oilfield, engineering construction quality becomes more and more important in infrastructure construction of the oilfield. Generally speaking, engineering construction q...With rapid development of PetroChina's Qinghai Oilfield, engineering construction quality becomes more and more important in infrastructure construction of the oilfield. Generally speaking, engineering construction quality is related both to national economic development and safety of people and assets. To turn a design map into a materialized object, the construction project involves a large number of elements, such as design, materials, machinery, landform, geological factors, meteorological factors, construction process, technological measures and supervision system. Therefore, quality control holds the key to a construction project.展开更多
Current observations indicate that 95% of the energy density in the universe is the unknown dark component.The dark component is considered composed of two fluids:dark matter and dark energy.Or it is a mixture of thes...Current observations indicate that 95% of the energy density in the universe is the unknown dark component.The dark component is considered composed of two fluids:dark matter and dark energy.Or it is a mixture of these two dark components,i.e.,one can consider it an exotic unknown dark fluid.With this consideration,the variable generalized Chaplygin gas(VGCG)model is studied with not dividing the unknown fluid into dark matter and dark energy parts in this paper.By using the Markov Chain Monte Carlo method,the VGCG model as the unification of dark sectors is constrained,and the constraint results on the VGCG model parameters are,n=0.00057+0.0001+0.0009-0.0006-0.0006,α=0.0015+0.0003+0.0017-0.0015-0.0015and B s=0.778+0.016+0.030-0.016-0.035,obtained by the cosmic microwave background data from the 7-year WMAP full data points,the baryon acoustic oscillation data from Sloan Digital Sky Survey(SDSS)and 2-degree Field Galaxy Redshift(2dFGRS)survey,and the Union2 type Ia supernova data with systematic errors.At last,according to the evolution of deceleration parameter it is shown that an expanded universe from deceleration to acceleration can be obtained in VGCG cosmology.展开更多
Supercapacitors are expected to bridge the gap between conventional electrostatic capacitors and batteries, but have not found significant application in primary energy devices, partly due to some unsolved problems in...Supercapacitors are expected to bridge the gap between conventional electrostatic capacitors and batteries, but have not found significant application in primary energy devices, partly due to some unsolved problems in the elec- trode materials. A wide range of novel materials such as novel carbons have been investigated to increase the energy den- sity of the electrodes and the volumetric merits of the materi- als need to be specifically considered and evaluated, towards the practical application of these novel materials. In obser- vation of the intense research activity to improve the volu- metric performance of carbon electrodes, the density or mass loading is particularly important and shall be further opti- mized, both for commercially applied activated carbons and in novel carbon electrode materials such as graphene. In this review, we presented a brief overview of the recent progress in improving the volumetric performance of carbon-based su- percapacitor electrodes, particularly highlighting the devel- opment of densified electrodes by various technical strategies including the controlled assembly of carbon building blocks, developing carbon based hybrid composites and constructing micro- supercapacitors.展开更多
The geographical and climatic patterning in craniofacial morphology among recent hominids has been regarded as relatively reliable evidence of environmental adaptation and natural selection,which is largely attributed...The geographical and climatic patterning in craniofacial morphology among recent hominids has been regarded as relatively reliable evidence of environmental adaptation and natural selection,which is largely attributed to thermoregulation.However,the relative influence of genetic and environmental factors on craniofacial features is unclear.Our study employed 3D laser scanning techniques to evaluate the association between geographical(latitude),climatic(annual temperature)factors,and 3D craniofacial measurements in 18 recent populations through bivariate correlation analysis.Significant correlations were found among braincase surface area,zygomatic bone surface area,cranial-facial index(facial surface area relative to braincase surface area)and local temperature,and a clear latitudinal gradient was also found in variation of braincase surface area.No significant correlations were found between zygomatic bone surface area,cranial-facial index and latitude.Our analysis supports the idea that the braincase functions as a radiator and is closely related to direct sunlight.We also suggest that absolute/relative craniofacial surface area varies consistently with predictions derived from Bergmann’s Rule.The mosaic craniofacial traits of American Indians may reflect retention of cold-derived,ancestral features,as well as a response to a slightly warmer climate.Because different craniofacial regions preserve environmental/genetic signatures differentially,caution is suggested when craniofacial anatomy is used for phylogenetic reconstruction and functional-morphological analysis.展开更多
基金supported by the Foundation for Military Medicine,China,No.BWS11J035(to JPF)the Key Disciplines Group Construction Project of Pudong Health Bureau of Shanghai of China,No.PWZxq2017-09(to XPC and JPF)
文摘Olfactory ensheathing cells from the olfactory bulb and olfactory mucosa have been tbund to increase axonal sprouting and pathfinding and promote the recovery of vibrissae motor performance in facial nerve transection injured rats. However, it is not yet clear whether olfactory ensheathing cells promote the reparation of facial nerve defects in rats. In this study, a collagen sponge and silicone tube neural conduit was implanted into the 6-mm defect of the buccal branch of the facial nerve in adult rats. Olfactory ensheathing cells isolated from the olfactory bulb of newborn Sprague-Dawley rats were injected into the neural conduits connecting the ends of tile broken nerves, the morphology and function of the regenerated nerves were compared between the rats implanted with olfactory ensheathing cells with the rats injected with saline. Facial paralysis was assessed. Nerve electrography was used to measure facial nerve-induced action potentials. Visual inspection, anatomical microscopy and hematoxylin-eosin staining were used to assess the histomorphology around the trans planted neural conduit and the morphology of the regenerated nerve. Using fluorogold retrograde tracing, toluidine blue staining and lead uranyl acetate staining, we also measured the number of neurons in the anterior exterior lateral f:acial nerve motor nucleus, the number of myelinated nerve fibers, and nerve fiber diameter and myelin sheath thickness, respectively. After surgery, olfactory ensheathing cells de- creased facial paralysis and the latency of the facial nerve-induced action potentials. There were no differences in the general morphology of the regenerating nerves between the rats implanted with olfactory ensheathing cells and the rats injected with saline. Between-group results showed that olfactory ensheathing cell treatment increased the number of regenerated neurons, improved nerve fiber morphology, and increased the number of myelinated nerve fibers, nerve fiber diameter, and myelin sheath thickness. In conclusion, implantation of olfactory ensheathing cells can promote regeneration and functional recovery after facial nerve damage in rats.
基金Supported by the Natural Science Foundation of Liaoning Province, China (20052193) and Ph.D. Programs Foundation of Ministry of Education o f China (20070141045).
文摘To improve the separation performance of a supersonic gas separation device for the treatment of gas mixture with a single heavy component, a novel structure with shorter settlement distance was constructed and a method of droplet enlargement was applied. A series of experiments were carried out in the improved separation device under various conditions, using air-ethanol vapor as the medium and micro water droplets as nucleation cen- ters. The effects of the inlet pressure, temperature and relative humidity, the swirling intensity, and mass flow rate of water on the separation performance were investigated. The separation was improved by increasing the inlet pressure and relative humidity. With the decrease of swirling intensity and mass flow rate of water, the separation efficiency increased first and then decreased. The inlet temperature had a slight effect on the separation. The results showed that the separation performance was effectively improved using the proposed structure and method, and the best separation in this study was obtained with the ethanol removal rate about 55% and dew point depression 27 K. The addition of water had little pollution to the air-ethanol vapor system since the water carry-over rate was within the range of -2 %-0 in most cases.
基金Project(51108485)supported by the National Natural Science Foundation of ChinaProject(20110191120033)supported by the Specialized Research Fund for the Doctoral Program of Higher Education of China+1 种基金Projects(106112013CDJZR200001,CDJZR12200012)supported by the Fundamental Research Funds for the Central Universities,ChinaProject(cstc2013jcyjA30005)supported by the Natural Science Foundation of Chongqing,China
文摘The unsaturated undisturbed quaternary system middle pleistocene loess,a typical unsaturated soil,often occurs in the implementation of western development strategy.To obtain the shearing strength characteristics of this unsaturated undisturbed loess,based on the analysis of mineral composition,the triaxial shear test of undisturbed quaternary system middle pleistocene loess under different moisture contents is conducted with the specialized triaxial instrument for unsaturated soil.The test results show that the mainly mineral composition of undisturbed quaternary system middle pleistocene loess is quartz and albite.Under the same confining pressure,the matric suction increases with the decrease of moisture content.The smaller the moisture content,the larger the matric suction;the higher the moisture content,the lower the matric suction.Under the same moisture content,the matric suction increases with the confining pressure and reaches a maximum when the confining pressure is 100 kPa,and then decreases with the increase of confining pressure.This phenomenon is closely related to the grain contact tightness of soil mass under high confining pressure.According to the triaxial test of loess,the sample of loess experiences 4 stages from loading to failure:1) compaction stage;2) compression stage;3) microcrack developing stage;4) shear failure stage.The test sample is of brittle failure(weak softening)under low moisture content and confining pressure.With the decrease of matric suction and the increase of consolidated confining pressure,the stress-strain curve changes from softening type to ideal plastic type.In the shearing strength parameters of unsaturated undisturbed loess,the influence of moisture content on internal friction angle is small,but that on cohesive force is obvious.Therefore,the shearing strength of unsaturated undisturbed loess is higher than that of saturated undisturbed loess and varies with the moisture content.
基金Supported by the National Natural Science Foundation of China(No.41030856)the Taishan Scholar Project
文摘Previous studies carried out in the East China Sea (ECS) mud area focused on long-term environmental changes in sedimentary records during the Holoeene, especially during the mid-Holocene high-stand water levels period. These results indicate that sensitive grain size groups can be used as a sedimentary proxy to reconstruct the evolution of the East Asian Winter Monsoon (EAWM). The studies have been carried out mainly in the northern and middle portions of the Zhejiang-Fujian coastal mud, however, similar research in the southern portion and the comparison between sedimentary proxy and modern measured data of EAWM are lacking. In this paper, we focused on a sedimentary record of the past 100 years with an enhanced resolution of 1.8 years. Investigations of the southern end of the Zhejiang-Fujian coastal mud area were conducted on the basis of 21~Pb chronology, grain-size analysis and chemical element analysis. The correspondence between the mean grain size (Mz) of sediment sensitive grain size and the measured EAWM was confirmed for the first time. We found that during the recent 100 years, the variation of the mean grain size of the sensitive population in the southern portion of the Zhejiang-Fujian mud was mainly controlled by the EAWM intensity changes; and not directly related to changes in the sediment discharge from Datong station of the Changjiang River (DTSD). Finally, recent changes in the content of heavy metals in study area reflect the impact of human activities on the environment.
基金Project(50678052) supported by the National Natural Science Foundation of China
文摘In order to establish the baseline finite element model for structural health monitoring,a new method of model updating was proposed after analyzing the uncertainties of measured data and the error of finite element model.In the new method,the finite element model was replaced by the multi-output support vector regression machine(MSVR).The interval variables of the measured frequency were sampled by Latin hypercube sampling method.The samples of frequency were regarded as the inputs of the trained MSVR.The outputs of MSVR were the target values of design parameters.The steel structure of National Aquatic Center for Beijing Olympic Games was introduced as a case for finite element model updating.The results show that the proposed method can avoid solving the problem of complicated calculation.Both the estimated values and associated uncertainties of the structure parameters can be obtained by the method.The static and dynamic characteristics of the updated finite element model are in good agreement with the measured data.
文摘With rapid development of PetroChina's Qinghai Oilfield, engineering construction quality becomes more and more important in infrastructure construction of the oilfield. Generally speaking, engineering construction quality is related both to national economic development and safety of people and assets. To turn a design map into a materialized object, the construction project involves a large number of elements, such as design, materials, machinery, landform, geological factors, meteorological factors, construction process, technological measures and supervision system. Therefore, quality control holds the key to a construction project.
基金supported by the National Natural Science Foundation of China(Grant Nos.11147150,11205078,and 11275035)the Natural Science Foundation of Education Department of Liaoning Province(Grant No.L2011189)
文摘Current observations indicate that 95% of the energy density in the universe is the unknown dark component.The dark component is considered composed of two fluids:dark matter and dark energy.Or it is a mixture of these two dark components,i.e.,one can consider it an exotic unknown dark fluid.With this consideration,the variable generalized Chaplygin gas(VGCG)model is studied with not dividing the unknown fluid into dark matter and dark energy parts in this paper.By using the Markov Chain Monte Carlo method,the VGCG model as the unification of dark sectors is constrained,and the constraint results on the VGCG model parameters are,n=0.00057+0.0001+0.0009-0.0006-0.0006,α=0.0015+0.0003+0.0017-0.0015-0.0015and B s=0.778+0.016+0.030-0.016-0.035,obtained by the cosmic microwave background data from the 7-year WMAP full data points,the baryon acoustic oscillation data from Sloan Digital Sky Survey(SDSS)and 2-degree Field Galaxy Redshift(2dFGRS)survey,and the Union2 type Ia supernova data with systematic errors.At last,according to the evolution of deceleration parameter it is shown that an expanded universe from deceleration to acceleration can be obtained in VGCG cosmology.
基金supported by the Chinese Government 1000 Plan Talent Programthe Ministry of Education's Program for New Century Excellent Talents in the University+2 种基金the National Natural Science Foundation of China(51322204)the Fundamental Research Funds for Central Universities(WK2060140014 and WK2060140017)the funding from Hefei National Synchrotron Radiation Lab
文摘Supercapacitors are expected to bridge the gap between conventional electrostatic capacitors and batteries, but have not found significant application in primary energy devices, partly due to some unsolved problems in the elec- trode materials. A wide range of novel materials such as novel carbons have been investigated to increase the energy den- sity of the electrodes and the volumetric merits of the materi- als need to be specifically considered and evaluated, towards the practical application of these novel materials. In obser- vation of the intense research activity to improve the volu- metric performance of carbon electrodes, the density or mass loading is particularly important and shall be further opti- mized, both for commercially applied activated carbons and in novel carbon electrode materials such as graphene. In this review, we presented a brief overview of the recent progress in improving the volumetric performance of carbon-based su- percapacitor electrodes, particularly highlighting the devel- opment of densified electrodes by various technical strategies including the controlled assembly of carbon building blocks, developing carbon based hybrid composites and constructing micro- supercapacitors.
基金supported by the Chinese Academy of Sciences (Grant Nos. KZZD-EW-03, XDA05130100, GJHZ201314)the National Natural Science Foundation of China (Grant No. 41272034)
文摘The geographical and climatic patterning in craniofacial morphology among recent hominids has been regarded as relatively reliable evidence of environmental adaptation and natural selection,which is largely attributed to thermoregulation.However,the relative influence of genetic and environmental factors on craniofacial features is unclear.Our study employed 3D laser scanning techniques to evaluate the association between geographical(latitude),climatic(annual temperature)factors,and 3D craniofacial measurements in 18 recent populations through bivariate correlation analysis.Significant correlations were found among braincase surface area,zygomatic bone surface area,cranial-facial index(facial surface area relative to braincase surface area)and local temperature,and a clear latitudinal gradient was also found in variation of braincase surface area.No significant correlations were found between zygomatic bone surface area,cranial-facial index and latitude.Our analysis supports the idea that the braincase functions as a radiator and is closely related to direct sunlight.We also suggest that absolute/relative craniofacial surface area varies consistently with predictions derived from Bergmann’s Rule.The mosaic craniofacial traits of American Indians may reflect retention of cold-derived,ancestral features,as well as a response to a slightly warmer climate.Because different craniofacial regions preserve environmental/genetic signatures differentially,caution is suggested when craniofacial anatomy is used for phylogenetic reconstruction and functional-morphological analysis.