融合关系挖掘与协同过滤的物品冷启动推荐算法

针对新物品缺乏(非完全冷启动)或没有(完全冷启动)评分信息,协同过滤无法为新物品进行个性化推荐的问题,文中提出融合关系挖掘与协同过滤的推荐算法.首先,利用关系挖掘提取物品关系特征,根据属性之间的多种二元关系构建关系属性,丰富可用属性信息.然后,提出基于关系挖掘的近邻选取方法,增加邻近物品的多样性.最后,融合协同过滤方法,同时解决完全和非完全新物品冷启动问题,实现新物品的个性化推荐.在两个真实数据集上的实验表明,文中方法可以系统解决推荐系统中新物品的冷启动问题.

产品时效性感知的个性化推荐算法

在实际生活中,许多产品具有时效性,人们对于新产品和旧产品的选择通常会基于不同的理由.因此,在推荐中应该考虑这种差异.然而,目前的推荐算法中并没有考虑这种差异性.文中在分析产品时效性的基础上,提出一种时效性感知的个性化推荐方法,它采用了联合矩阵分解的算法,将产品按时效性划分为多个矩阵,再将其联合训练.这样既考虑到了时效性,又克服了产品的稀疏性,并且联合训练又可以得到产品的某种特征向量,挖掘划分成多个部分的时效性产品之间的内部联系.并将流行度作为正则化项.实验表明,该方法可以得到具备良好的推荐性能.

Prediction Method Study on the Remaining Useful Life of Plant New Varieties Rights Based on Weibull Survival Function and Gaussian Model——Taking Hybrid Rice Variety for Example

In view of the difficulty in determining remaining useful life of plant new variety right in economic analysis, Weibull Survival Analysis Method and Gaussian Model to were used to study how to accurately estimate the remaining useful life of plant new variety right. The results showed that the average life of the granted rice varieties was 10.013 years. With the increase of the age of plant variety rights, the probability of the same residual life Ttreaching x was smaller and smaller, the reliability lower and lower, while the probability of the variety rights becoming invalid became greater. The remaining useful life of a specific granted rice variety was closely related to the demonstration promotion age when the granted rice variety reached its maximum area and the appearance of alternative varieties, and when the demonstration promotion age of the granted rice variety reaching the one with the maximum area, the promotion area would be decreased once a new alternative variety appeared, correspondingly with the shortening of the remaining useful life of the variety. Therefore, Weibull Survival Analysis Method and Gaussian Model could describe the remaining useful life＇s time trend, as well as determine the remaining useful life of a concrete plant variety right, clarify the entire life time of varieties rights, and make the economic analysis of plant new varieties rights more accurate and reasonable.

The Analysis of the Influencing Factors on the Implementing Effects of Plant Breeders' Rights(PBR)System in China

The implementing effects of plant breeders＇ rights（PBR）system is influenced by many factors,such as knowledge of the PBR system,the expense of time for the application and approval,the cost of the applying case,etc..Statistical analysis was carried out based on the above influencing factors by means of questionnaire to find out specific reasons.The result suggests that weak propagandizing;inappropriate propagandizing patterns and obstructed approaches for new regulations are all negatively contributing to the PBR.Meanwhile,current PBR system in China which has been found with many irrational aspects affected the impractical design of regulatory operation and the examining efficiency.Lastly,several suggestions were offered on the base of the results.

Eualus heterodactylus sp.nov.,a new hippolytid shrimp from Chinese coast of the Yellow Sea(Crustacea,Decapoda,Caridea)

A new species from the caridean family Hippolytidae,Eualus heterodactylus sp.nov.is described and illustrated based on the specimens collected from Chinese coast of the Yellow Sea.The new species is a part of an informal species group characterized by the possession of epipods on the anterior three pairs of pereopods,and is distinguished from other species of this group by the dactyli of the third to fifth pereopods possessing distinctly stair-like flexor margins in males.

Advances in DUS Test Technique for Coconut

As great progress has been made in the field of protection of new plant varieties, more attention is paid to the standardization of DUS(Distinctness, Uniformity, and Stability) test procedure. For further studies of tropical plants as their importance in agriculture and germplasm, protection of coconut becomes more significant and thus DUS test technique of coconut is needed. In this essay, we analyzed the status quo of the DUS test guidelines by International Union for the Protection of New Varieties of Plants(UPOV proj.3) and national DUS test guidelines in China, and provided some suggestions or promotions for improving the guidelines of DUS test in coconut.

Breeding of New Japonica-indica Hybrid Rice Combination Chunyou 59

Chunyou 59 is a japonica-indica hybrid rice combination developed from Chunjiang 16A(a late japonica CMS line with dwarfness and early anthesis time)and CH59(an indicaclinous wide compatibility restorer line).It has the characteristics of strong heterosis,strong stem,good lodging resistance,large panicles,good cold tolerance,high yield and wide adaptability.It was registered and released by Jiangxi Provincial Crop Variety Appraisal Committee in March 2009.The breeding procedure,characteristics,major techniques of cultivation and seed production of Chunyou 59 were introduced in the paper.

The Combinatorial Biosynthesis of＂Unnatural＂ Products with Polyketides

Polyketides have been widely used clinically due to their significant biological activities, but the needed structural and functional diversity cannot be achieved by common chemical synthetic methods. The tool of combinatorial biosynthesis provides the possibility to produce "unnatural" natural drugs, which has achieved initial success. This paper provides an overview for the strategies of combinatorial biosynthesis in producing the structural and functional diversity of polyketides, including the redesign of metabolic flow, polyketide synthase(PKS) engineering, and PKS post-translational modification. Although encouraging progress has been made in the last decade, challenges still exist regarding the rational combinatorial biosynthesis of polyketides. In this review, the perspectives of polyketide combinatorial biosynthesis are also discussed.

Some Thoughts on Science-based Botanical Garden Establishment

Through analysis of the historical and present development of botanical gardens, both domestic and international, with particular focus on botanical garden practices within the Chinese Academy of Sciences (CAS), the authors propose that science-based botanical gardens (which differ from common public gardens), should be founded on plant diversity inventory and ex-situ conservation of wild plant species. Efforts should be directed to rarer species from biodiversity-rich areas and biodiversity hotspots, utilizing cutting-edge technologies to effectively preserve germplasm in living collections. Science-based botanical garden management should be directed by sound scientific evaluation of plant resources and guaranteed by innovative operational mechanisms. Science-based botanical gardens should also emphasize the establishment of identifiable and specialized living collections, research platforms and recruitment of qualified experts. In addition to curating living specimens, science-based botanical gardens should pursue research and development of new plant varieties or patents based on their plant collections, thus providing continual support to bio-industry.

Erythropoietin： From a Biosimilar to Innovative Products Protected by Industrial Property Assets

Aim： EPO （erythropoietin） is a hormone that stimulates the erythropoiesis and is mainly produced by the kidneys. In the early 1990s among the emerging biotech drugs, the recombinant human EPO （rhEPO） was the best-selling product worldwide, reaching nearly three billion dollars annually. The CIM （center of molecular immunology） produced and sold the rhEPO as commercial strategy to recover the investment made in its new facilities. This work summarizes the inventions that protect the innovative products developed by three Cuban institutions, starting from rhEPO, and the industrial property strategy followed by them. Methods： The information was obtained from the United States Patent, Trademark Office （USPTO） database, Patentscope, Espacenet, patent databases of Center for Pharmaceutical Research and Drug Development （CIDEM） and Cuban Industrial Property Office. Conclusions： The manufacturing process of CIM＇s EPO has its own patent family. From a manufacturing by product an innovative formulation protected by patent was obtained. There is a patent family around the nasal formulation and it continues enlarging. From a biosimilar pharmaceutical innovative products impacting on human health have been obtained.

Tbio-Model of a Start-up with Focus in Biotechnological Solutions for Coffee Chain

Tbio is a start-up created to give support to commercialize the products of the biofactory installed in the Federal University of Lavras, Minas Gerais State, Brazil, part of the Innovation Program developed by this University. Its specialty is to innovate, through biological solutions with the vision of the future, once there is a strong demand of food and beverages free of chemical residues and with lower employing of these substances along the production chain by several consumers. The innovative products are generated from microorganisms tested regarding its capacity to promote yield protection, pests and disease control, acceleration of the desmucilage waste water treatment, and improvement of process of faster solubilization, that depends on natural phosphate fertilizers. The goal of this article is to approach the activities that have been developed in this start-up and the knowledge about biocontrol and natural antimicrobials produced by fungi resulting in innovative products to attend the world claim for products free of chemical residues of any kind and harmless to the consumers, environment and workers.

A Proposed New Product Development Process for Floor Coverings and Assessment of Its Applicability

Nowadays, the rapid changes in the marketing environment of construction products accelerate the shortening tendency of product life cycles which in return put pressure on companies to produce successful new products and adopt innovative strategies to survive and expand in the fast competitive environment. The success of the new construction products calls for a high-quality and well-managed product development process. Thus, this study aims at defining the basic steps of a NPD （new product development） process designed for floor coverings and evaluating its applicability. To this end, the product development methods of the leading companies in the construction sector in Turkey have been analyzed. Also, a questionnaire has been conducted to determine which of the steps of the proposed methodology are currently being realized and which are not or cannot be implemented. Finally, based on this information, certain suggestions have been made as to what can be done to enhance the NPD processes of the companies＇ subject to evaluation.

Urban Consumer Attitudes to Fresh Produce Safety in China

The objective of this study was to explain the determinants of the fresh vegetables purchase decision by Chinese urban consumers in Beijing including awareness and attitudes to food safety, and their willingness to pay （WTP） more for specific safety characteristics when buying fresh vegetables. The research rationale arises out of a history of food safety scares and scandals in China, and a national government response to promote quality assurance and safety through labelling. The primary hypothesis was that an understanding of food safety systems and product labelling, and trust in supply chain integrity would be key determinants in consumer willingness to purchase and pay more for safety assured vegetables. Based on a questionnaire survey of consumers in Beijing, the analysis found that the major factors underlying the purchase decision of fresh vegetables were product freshness, convenience and competitive price rather than assured product labelling. The decisions whether to purchase assurance-labelled vegetables and WTP more for chemical residue-free product were analysed by binomial and ordinal multinomial logit modelling respectively. It revealed a WTP moreof between 20% and 40%. Monthly household income was a key determinant of both quality assured product and WTP, together with degree of concern over residues, trust in retailer and assurance labels and place of purchase. The results suggest much still remains to be done to build trust though rigorous monitoring and enforcement of food safety standards to improve supply chain integrity and consumer confidence.