关于中央大街城市景观的调研及思考

中央大街,北起松花江防洪纪念塔,南至经纬街,全长1450米,宽21.34米。其中车行方石路宽10.8米。全街建有欧式及仿欧式建筑71栋,其中保护性建筑13栋。1986年,哈尔滨市人民政府将中央大街确定为保护街路。1996年8月,市政府决定将其改造成步行街,并于1997年6月1日正式开通,是全国较早的步行街之一。步行街全长860米,设有休闲区6个,两侧人行道铺装广场砖近5000平方米,彩色步道板2500平方米,并在大安街至东风街路段铺设500米的轮椅通道。改建后的步行街环境优美,秩序井然。她以其独特的欧式建筑、精致典雅牌匾广告、欧式古典路灯、花团锦簇的休闲小区以及异彩纷呈的文化生活,成为哈尔滨市一道亮丽的风景线。

Appropriate kidney stone size for ureteroscopic lithotripsy:When to switch to a percutaneous approach

Flexible ureteroscopy(f URS) has become a more effective and safer treatment for whole upper urinary tract stones. Percutaneous nephrolithotomy(PNL) is currently the first-line recommended treatment for large kidney stones ≥ 20 mm and it has an excellent stone-free rate for large kidney stones. However, its invasiveness is not negligible considering its major complication rates. Staged f URS is a practical treatmentfor such large kidney stones because f URS has a minimal blood transfusion risk, short hospitalization and few restrictions on daily routines. However, as the stone size becomes larger, the stone-free rate decreases, and the number of operations required increases. Therefore, in our opinion, staged f URS is a practical option for kidney stones 20 to 40 mm. Miniaturized PNL combined with f URS should be considered to be a preferred option for stones larger than 40 mm. Moreover, URS is an effective treatment for multiple upper urinary tract stones. Especially for patients with a stone burden < 20 mm, URS is a favorable option that promises a high stone-free rate after a single session either unilaterally or bilaterally. However, for patients with a stone burden ≥ 20 mm, a staged operation should be considered to achieve stone-free status.

Strategies to optimizeshockwavelithotripsy outcome:Patient selection and treatment parameters

Shock wave lithotripsy(SWL) was introduced in 1980, modernizing the treatment of upper urinary tract stones, and quickly became the most commonly utilized technique to treat kidney stones. Over the past 5-10 years, however, use of SWL has been declining because it is not as reliably effective as more modern technology. SWL success rates vary considerably and there is abundant literature predicting outcome based on patient- and stone-specific parameters. Herein we discuss the ways to optimize SWL outcomes by reviewing proper patient selection utilizing stone characteristics and patient features. Stone size, number, location, density, composition, and patient body habitus and renal anatomy are all discussed. We also review the technical parameters during SWL that can be controlled to improve results further, including type of anesthesia, coupling, shock wave rate, focal zones, pressures, and active monitoring. Following these basic principles and selection criteria will help maximize success rate.

Urolithiasis in inflammatory bowel disease and bariatric surgery

AIM To analyse current literature focusing on pathogenesis and therapeutic aspects of urolithiasis with inflammatory bowel disease(IBD) and following bariatric surgery. METHODS A systematic literature search was performed using PubMed, supplemented with additional references. Studies assessing the association of IBD or bariatric surgery with renal stones in both paediatric and adulthood were included. RESULTS Certain types of stones are seen more frequently with IBD. Hyperoxaluria and hypocitraturia are the main metabolic changes responsible for urolithiasis. The incidence of renal stones in malabsorptive types of bariatric surgery such as gastric bypass is high; this is not as common in modern restrictive surgical methods. Preventative methods and urine alkalinisation have been shown to be beneficial.CONCLUSION Both conditions are associated with renal stones. Patients' counselling and prevention strategies are the mainstay of urolithiasis management in these patients.

Bone disease in pediatric idiopathic hypercalciuria

Idiopathic hypercalciuria （IH） is the leading metabolic risk factor for urolithiasis and affects all age groups without gender or race predominance. IH has a high morbidity with or without lithiasis and reduced bone mineral density （BMD）, as described previously in pe-diatric patients as well as in adults. The pathogenesis of IH is complex and not completely understood, given that urinary excretion of calcium is the end result of an interplay between three organs （gut, bone and kidney）, which is further orchestrated by hormones, such as 1,25 dihydroxyvitamin D, parathyroid hormone, calcitonin and fosfatonins （i.e., fbroblast growth-factor-23）. Usu-ally, a primary defect in one organ induces compensa-tory mechanisms in the remaining two organs, such as increased absorption of calcium in the gut secondary toa primary renal loss. Thus, IH is a systemic abnormality of calcium homeostasis with changes in cellular trans-port of this ion in intestines, kidneys and bones. Re-duced BMD has been demonstrated in pediatric patients diagnosed with IH. However, the precise mechanisms of bone loss or failure of adequate bone mass gain are still unknown. The largest accumulation of bone mass occurs during childhood and adolescence, peaking atthe end of the second decade of life. This accumulation should occur without interference to achieve the peak of optimal bone mass. Any interference may be a risk factor for the reduction of bone mass with increased risk of fractures in adulthood. This review will address the pathogenesis of IH and its consequence in bone mass.

Evaluation of Rock Fall Hazards Using Lidar Technology

Lidar （light detection and ranging） is a relatively new technology that is being used in many aspects of geology and engineering, including researching the potential for rock falls on highway rock cuts. At Missouri University of Science and Technology, we are developing methods for measuring joint orientations remotely and quantifying the raveling process. Measuring joint orientations remotely along highways is safer, more accurate and can result in larger and more accurate data sets, including measurements from otherwise inaccessible areas. Measuring the nature of rock raveling will provide the data needed to begin the process of modeling the rock raveling process. In both cases, terrestrial lidar scanning is used to generate large point clouds of coordinate triplets representing the surface of the rock cut. Automated algorithms have been developed to organize the lidar data, register successive images without survey control, and removal of vegetation and non-rock artifacts. In the first case, we look for planar elements, identify the plane and calculate the orientations. In the second case, we take a series of scans over time and use sophisticated change detection algorithms to calculate the numbers and volumes of rock that has fallen off the rock face.