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基于“方药量-效关系”研究大黄黄连泻心汤治疗糖尿病 被引量:5
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作者 杨霞 梁永林 +3 位作者 王志刚 柳荣 赵怡坤 周琦 《陕西中医药大学学报》 2023年第1期40-43,共4页
通过对大黄黄连泻心汤的药效物质基础及临床作用机制研究,发现大黄黄连泻心汤及其单味中药大黄、黄连、黄芩对糖尿病及其并发症均有一定的防治作用,可以显著改善胰岛素抵抗,具有降血糖、调血脂的功效,且可拮抗胰岛β细胞的损伤,促进β... 通过对大黄黄连泻心汤的药效物质基础及临床作用机制研究,发现大黄黄连泻心汤及其单味中药大黄、黄连、黄芩对糖尿病及其并发症均有一定的防治作用,可以显著改善胰岛素抵抗,具有降血糖、调血脂的功效,且可拮抗胰岛β细胞的损伤,促进β细胞再生及功能恢复,促进胰岛素的分泌。“中医不传之秘在于量”,方药剂量直接影响中医药临床疗效,由相同的药物组成的方剂,因剂量的不同而作用悬殊;单味中药在方中因剂量不同而发挥的作用差别也很大。大黄黄连泻心汤基于“方药量-效关系”治疗糖尿病的研究时,药物的用量与其在方中的功效具有密切相关性。 展开更多
关键词 大黄黄连泻心汤 方药量-效关系 糖尿病
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Survey of dose-effect relationship in Chinese materia medica
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作者 Hsiu-Ying Kao Yong Jiang 《TMR Modern Herbal Medicine》 2018年第4期249-258,共10页
The research on the dose-effect relationship in Chinese materia medica is delayed due to the complexity of its composition, multi-efficacy, multi-targeting and other factors. Many experts put forward re... The research on the dose-effect relationship in Chinese materia medica is delayed due to the complexity of its composition, multi-efficacy, multi-targeting and other factors. Many experts put forward relevant research ideas and methods and worked out more and more research results in literature, experimental and clinical categories because of the progress of statistical methods and scientific and technological means in recent years. In this paper, these results were preliminarily combed to show the basic situation of dose-effect relationship research in Chinese materia medica. 展开更多
关键词 Traditional Chinese Medicine Chinese medicinal Chinese materia medica Dose-effect relationship Research progress Research overview
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