The coupling of water and fertilizer is the only way for high yield, efficiency, sugar on sugarcane. On sugarcane production, the spatial and temporal controlling technology of fertigation is an important direction of...The coupling of water and fertilizer is the only way for high yield, efficiency, sugar on sugarcane. On sugarcane production, the spatial and temporal controlling technology of fertigation is an important direction of the sustainable and healthy development of ecological agriculture in cane area of China. This paper reviews main achievements and advances on the coupling effect of water and fertilizer on sugarcane from time and space at home or abroad in recent years, analyzes the application prospects of the temporal and spatial coupling effect of water and fertilizer on sugarcane and puts forward some problems which need further research in future.展开更多
Land use plan serves as a leading role in land resource management, necessitating a powerful implementation guarantee system. The research concluded researches on guarantee system for land use plan from law, administr...Land use plan serves as a leading role in land resource management, necessitating a powerful implementation guarantee system. The research concluded researches on guarantee system for land use plan from law, administration, econo- my, society and technology. Finally, existing problems and suggestions were pro- posed.展开更多
OBJECTIVE To study the differential expression of COP9,JAK2,HSPS and NADH genes and their relationship with taxol resistance in ovarian carcinoma.METHODS The up-regulated genes for JAK2,HSPs and NADH,and the down-regu...OBJECTIVE To study the differential expression of COP9,JAK2,HSPS and NADH genes and their relationship with taxol resistance in ovarian carcinoma.METHODS The up-regulated genes for JAK2,HSPs and NADH,and the down-regulated COP9 gene,which have been demonstrated by a micro-array from our previous study,were examined by the reverse transcription-polymerase chain reaction(RT-PCR) and real-time-PCR in 33 tissue samples from ovarian cancer patients who previously had received taxol-based chemotherapy(Group1),and from 21 ovarian cancer cases who had never received chemotherapy before operation(Group2).RESULTS The expression rate of COP9 in Group 1 was shown to be markedly lower compared to Group 2(P = 0.000).However the expression rates of JAK2,HSPs and NADH in Group 1 were significantly higher than those in Group 2(all P = 0.000).The expression of COP9,HSPs and NADH showed no significant differences related to the histological grade.However,signifi cant higher expression of JAK2 was seen in Grade 3 compared to Grade 1～2(P = 0.000).We performed real-time PCR to conf irm the above fi ndings showing that the level of COP9 gene copies of Group 1 was much lower than that of Group 2(P = 0.007).Similarly,HSPs and NADH had significantly higher copy numbers in Group 1 compared to those patients who had not undergone chemotherapy(Group 2)(P = 0.018,P = 0.024,respectively).We also found that the JAK2 gene copy concentration in a TAX group was higher than in a non-TAX group(P = 0.001).In addition,we conf irmed a higher copy concentration of the JAK2 gene in Grade 3 compared to Grade 1～2 tumors(P = 0.000),though no signifi cant difference in the expression rates and gene copy concentrations of the 4 genes were seen among variable tumor types.CONCLUSION The down-regulation of COP9 and up-regulation of JAK2,HSPs,and NADH genes are related to the mechanism of drug-resistance in ovarian cancers.展开更多
Four mathematical models were systematically evaluated in describing responses of four different cropsat 7 rates of nitrogen application. Residual sum of squares and a total point ranking method were used toassess the...Four mathematical models were systematically evaluated in describing responses of four different cropsat 7 rates of nitrogen application. Residual sum of squares and a total point ranking method were used toassess the model fitting for crop responses to nitrogen application. Sparrow’s inverse quadratic polynomialmodel performed the best.展开更多
The use of Animal House Facilities of IPEN-CNEN/SP （Nuclear and Energetic Research Institute-National Nuclear Energy Commission/SP, Brazil） has provided rats and mice with controlled sanitary quality for research an...The use of Animal House Facilities of IPEN-CNEN/SP （Nuclear and Energetic Research Institute-National Nuclear Energy Commission/SP, Brazil） has provided rats and mice with controlled sanitary quality for research and quality control in the production of radiopharmaceuticals lots, produced at IPEN, following rules of CONCEA-Brazilian National Council for Animal Experimentation Control and approved in CEUA （Ethics Committee on the Use of Animals）, before they are sent to hospitals and clinics spread out in Brazil, for use in nuclear medicine. The production and the supply of high quality laboratory animals have fundamental importance for the accomplishment of vanguard scientific research, with reproducibility and universality. The quality of those animals depends, largely, on the available facilities for their production and lodging, to assure the demanded sanitary control and animal＇s welfare, in agreement with the ethical principles that control the activity. Therefore, the facilities design is of vital importance so that the mentioned requirements can be reached. Nevertheless, pigs and miniature pigs have gained importance as large animal models in medicine. With their size, organ capacity, and physiology resembling in several aspects that of humans, pigs are well suited for preclinical experiments and long-term safety studies. Minipigs will be used for preclinical testing of radiopharmaceuticals and assays radioactive materials for cardiac tests. This paper describes the premises and preliminary activities that have been performed at IPEN for the design of new Animal House Facilities dedicated to keeping minipigs taking into account fundamental aspects such as： animal＇s welfare, sanitation, genetic, in agreement with the ethical principles that control the activity and environmental concerns.展开更多
The core purpose of impact study was to collect best practices learnings of project through the reflection of communities or end users. During analysis and interpretation of data, some touch of context is also given t...The core purpose of impact study was to collect best practices learnings of project through the reflection of communities or end users. During analysis and interpretation of data, some touch of context is also given to clear the picture of weakness and strengths of project theory in terms of context. The main objective of project under study was to provide alternative energy to the communities living inside forest to reduce wood cutting for domestic purpose. Though there were many short term surveys were conducted during project, such as, average wood consumption at household level, community motivation survey. Instead to all MRDS （Mehran Research ＆ Development Society） felt need to conduct a detailed impact evaluation to see overall impact of project implementation and review on the life of end users or communities. After three years of project exit, MRDS conducted a qualitative impact study of project in the end of 2014. There were three key questions to explore during study： What was the overall impact of project on end users？ What the best practices of project and why？ What are project learnings and how？展开更多
Earthquake Early Warning ( EEW) has come to attention,as earthquake prediction is still unreliable. The paper comprehensively illustrates the research status and important issues of EEW from the aspects of concept,com...Earthquake Early Warning ( EEW) has come to attention,as earthquake prediction is still unreliable. The paper comprehensively illustrates the research status and important issues of EEW from the aspects of concept,composition and method. By analyzing the status of EEW in China,we find that the essential requirements have been met for building earthquake early warning systems in the country in terms of government and social needs, network construction and basic research. The technical difficulties and non-technical challenges in implementing EEW in China are evaluated, and some suggestions are proposed regarding the relevant legal measures,public education and protection against earthquake disasters. so as to bring into full play the role of the EEW system in earthquake disaster prevention and reduction.展开更多
基金Supported by Open Fund of Key Laboratory of Plant Nutrition and Fertilizer,Ministry of Agriculture(2013-1)Guangxi Natural Science Foundation for Youths(2011GXNSFB018026)+2 种基金Guangxi Scientific Research and Technological Development Program(14125008-2-15)Scientific and Technological Development Fund for Youths of Guangxi Academy of Agricultural Sciences(2013YQ18,2013YF06)the State Key Program of National Natural Science of China(U1033004-06)~~
文摘The coupling of water and fertilizer is the only way for high yield, efficiency, sugar on sugarcane. On sugarcane production, the spatial and temporal controlling technology of fertigation is an important direction of the sustainable and healthy development of ecological agriculture in cane area of China. This paper reviews main achievements and advances on the coupling effect of water and fertilizer on sugarcane from time and space at home or abroad in recent years, analyzes the application prospects of the temporal and spatial coupling effect of water and fertilizer on sugarcane and puts forward some problems which need further research in future.
文摘Land use plan serves as a leading role in land resource management, necessitating a powerful implementation guarantee system. The research concluded researches on guarantee system for land use plan from law, administration, econo- my, society and technology. Finally, existing problems and suggestions were pro- posed.
基金a grant from Beijing Captial Medicine Development Fundation(No.ZD199915)
文摘OBJECTIVE To study the differential expression of COP9,JAK2,HSPS and NADH genes and their relationship with taxol resistance in ovarian carcinoma.METHODS The up-regulated genes for JAK2,HSPs and NADH,and the down-regulated COP9 gene,which have been demonstrated by a micro-array from our previous study,were examined by the reverse transcription-polymerase chain reaction(RT-PCR) and real-time-PCR in 33 tissue samples from ovarian cancer patients who previously had received taxol-based chemotherapy(Group1),and from 21 ovarian cancer cases who had never received chemotherapy before operation(Group2).RESULTS The expression rate of COP9 in Group 1 was shown to be markedly lower compared to Group 2(P = 0.000).However the expression rates of JAK2,HSPs and NADH in Group 1 were significantly higher than those in Group 2(all P = 0.000).The expression of COP9,HSPs and NADH showed no significant differences related to the histological grade.However,signifi cant higher expression of JAK2 was seen in Grade 3 compared to Grade 1～2(P = 0.000).We performed real-time PCR to conf irm the above fi ndings showing that the level of COP9 gene copies of Group 1 was much lower than that of Group 2(P = 0.007).Similarly,HSPs and NADH had significantly higher copy numbers in Group 1 compared to those patients who had not undergone chemotherapy(Group 2)(P = 0.018,P = 0.024,respectively).We also found that the JAK2 gene copy concentration in a TAX group was higher than in a non-TAX group(P = 0.001).In addition,we conf irmed a higher copy concentration of the JAK2 gene in Grade 3 compared to Grade 1～2 tumors(P = 0.000),though no signifi cant difference in the expression rates and gene copy concentrations of the 4 genes were seen among variable tumor types.CONCLUSION The down-regulation of COP9 and up-regulation of JAK2,HSPs,and NADH genes are related to the mechanism of drug-resistance in ovarian cancers.
文摘Four mathematical models were systematically evaluated in describing responses of four different cropsat 7 rates of nitrogen application. Residual sum of squares and a total point ranking method were used toassess the model fitting for crop responses to nitrogen application. Sparrow’s inverse quadratic polynomialmodel performed the best.
文摘The use of Animal House Facilities of IPEN-CNEN/SP （Nuclear and Energetic Research Institute-National Nuclear Energy Commission/SP, Brazil） has provided rats and mice with controlled sanitary quality for research and quality control in the production of radiopharmaceuticals lots, produced at IPEN, following rules of CONCEA-Brazilian National Council for Animal Experimentation Control and approved in CEUA （Ethics Committee on the Use of Animals）, before they are sent to hospitals and clinics spread out in Brazil, for use in nuclear medicine. The production and the supply of high quality laboratory animals have fundamental importance for the accomplishment of vanguard scientific research, with reproducibility and universality. The quality of those animals depends, largely, on the available facilities for their production and lodging, to assure the demanded sanitary control and animal＇s welfare, in agreement with the ethical principles that control the activity. Therefore, the facilities design is of vital importance so that the mentioned requirements can be reached. Nevertheless, pigs and miniature pigs have gained importance as large animal models in medicine. With their size, organ capacity, and physiology resembling in several aspects that of humans, pigs are well suited for preclinical experiments and long-term safety studies. Minipigs will be used for preclinical testing of radiopharmaceuticals and assays radioactive materials for cardiac tests. This paper describes the premises and preliminary activities that have been performed at IPEN for the design of new Animal House Facilities dedicated to keeping minipigs taking into account fundamental aspects such as： animal＇s welfare, sanitation, genetic, in agreement with the ethical principles that control the activity and environmental concerns.
文摘The core purpose of impact study was to collect best practices learnings of project through the reflection of communities or end users. During analysis and interpretation of data, some touch of context is also given to clear the picture of weakness and strengths of project theory in terms of context. The main objective of project under study was to provide alternative energy to the communities living inside forest to reduce wood cutting for domestic purpose. Though there were many short term surveys were conducted during project, such as, average wood consumption at household level, community motivation survey. Instead to all MRDS （Mehran Research ＆ Development Society） felt need to conduct a detailed impact evaluation to see overall impact of project implementation and review on the life of end users or communities. After three years of project exit, MRDS conducted a qualitative impact study of project in the end of 2014. There were three key questions to explore during study： What was the overall impact of project on end users？ What the best practices of project and why？ What are project learnings and how？
基金funded by Key Projects in the National Science & Technology Pillar Program ( Grant No. 2012BAK19B04)the National Natural Science Foundation ( Grant No. 41104023)the Science & Technology Development Project of Shandong Province ( Grant No. 2011GSF12004)
文摘Earthquake Early Warning ( EEW) has come to attention,as earthquake prediction is still unreliable. The paper comprehensively illustrates the research status and important issues of EEW from the aspects of concept,composition and method. By analyzing the status of EEW in China,we find that the essential requirements have been met for building earthquake early warning systems in the country in terms of government and social needs, network construction and basic research. The technical difficulties and non-technical challenges in implementing EEW in China are evaluated, and some suggestions are proposed regarding the relevant legal measures,public education and protection against earthquake disasters. so as to bring into full play the role of the EEW system in earthquake disaster prevention and reduction.
