[Objective]The aim was to study the sensitive response characteristics of the main agronomic traits of somaclonal and the variation of sensitive response of the lines of somaclonal to sowing date. [Method]The RITSD ch...[Objective]The aim was to study the sensitive response characteristics of the main agronomic traits of somaclonal and the variation of sensitive response of the lines of somaclonal to sowing date. [Method]The RITSD changing of agronomic traits was studied by using 24 rice somaclonal and its donor parent under two sowing dates. [Result]The average values of RITSD were higher （over one） for the traits of pant height （PH）,density of spikelets （DS）,filled spikelets per panicle （FSP）,spikelets per panicle （SP） and grain weight per plant （GWP）,but lower for days of sowing to heading （DSH）,effective panicles （EP）,panicle length （PL）,seed setting rate （SS） and 1 000-grain weight （1 000-GW）. These showed that PH,DS,FSP,SP and GWP were easily affected by sowing date and tended to higher with the later sowing; the RITSD of somaclonal changed with the agronomic traits. The frequency of RITSD＇ variation of DSH and PH was higher than that of PL. The RITSD＇ value of EP,PL,DS,FSP,SP and SS became higher,and higher or lower for DSH and GWP in different somaclonal; compared with the donor,20 of 24 was significantly different,and the frequency of RITSD variation was over 83. 3%,however,RITSD of the most lines （75%） changed only for 1-2 characters; cluster analysis showed that the RITSD of agronomic traits belonged to different combinations of somaclonal in rice. [Conclusion]the study had provided a theoretical basis for the screening and using of the somaclonal.展开更多
In the fight against cancer, controlled drug delivery systems have emerged to enhance the therapeutic efficacy and safety of anti-cancer drugs. Among these systems, mesoporous silica nanoparticles （MSNs） with a func...In the fight against cancer, controlled drug delivery systems have emerged to enhance the therapeutic efficacy and safety of anti-cancer drugs. Among these systems, mesoporous silica nanoparticles （MSNs） with a functional surface possess obvious advantages and were thus rapidly developed for cancer treatment. Many stimuli-responsive materials, such as nanopartides, polymers, and inorganic materials, have been applied as caps and gatekeepers to control drug release from MSNs. This review presents an overview of the recent progress in the production of pH-responsive MSNs based on the pH gradient between normal tissues and the tumor microenvironment. Four main categories of gatekeepers can respond to acidic conditions. These categories will be described in detail.展开更多
In frequency domain,the power spectrum of Low-rate denial of service(LDoS) attacks is totally spread into the spectrum of normal traffic.It is a challenging task to detect and filter LDoS attack flows from the normal ...In frequency domain,the power spectrum of Low-rate denial of service(LDoS) attacks is totally spread into the spectrum of normal traffic.It is a challenging task to detect and filter LDoS attack flows from the normal traffic.Based on the analysis of LDoS attack flows and legitimate TCP traffic in time and frequency domains,the periodicity of the TCP traffic and LDoS attack flows is explored to facilitate the research of network traffic processing.Hence,an approach of LDoS attack flow filtering based on frequency spectrum analysis is proposed.In this approach,the TCP traffic and LDoS attack flows are transformed from the time domain into the frequency domain.Then the round-trip time(RTT) is estimated by using frequency domain search method.Analysis of amplitude spectrum shows that TCP traffic energy is mainly concentrated on the points of n/RTT.Therefore,a comb filter using infinite impulse response(IIR) filter is designed to filter out the LDoS attack flows in frequency domain,while most legitimate TCP traffic energy at the points of n/RTT are pass through.Experimental results show that the maximum pass rate for legitimate TCP traffic reaches 92.55%,while the maximum filtration rate of LDoS attack flows reaches 81.36%.The proposed approach can effectively filter the LDoS attack flows while less impact on the legitimate TCP traffic.展开更多
A new sub-nanosecond pulse generator scheme is proposed in the opinion of frequency field in this paper. The filtering techniques used in the UWB (ultra-wideband) generator make the circuit simple and suitable for int...A new sub-nanosecond pulse generator scheme is proposed in the opinion of frequency field in this paper. The filtering techniques used in the UWB (ultra-wideband) generator make the circuit simple and suitable for integration. The theoretical analysis and simulation results show that monocycle form generated in the scheme have a good balance between positive and negative shape and small traipse by circuit parameter control and has improved the quality of UWB pulse form.展开更多
基金Supported by Chongqing Major Research Project "Innovation in Hybrid Rice Breeding and New Materials" ( CSTC, 2007, AA1019 )Sichuan Province Breeding Research Project (06yzgg-01)~~
文摘[Objective]The aim was to study the sensitive response characteristics of the main agronomic traits of somaclonal and the variation of sensitive response of the lines of somaclonal to sowing date. [Method]The RITSD changing of agronomic traits was studied by using 24 rice somaclonal and its donor parent under two sowing dates. [Result]The average values of RITSD were higher （over one） for the traits of pant height （PH）,density of spikelets （DS）,filled spikelets per panicle （FSP）,spikelets per panicle （SP） and grain weight per plant （GWP）,but lower for days of sowing to heading （DSH）,effective panicles （EP）,panicle length （PL）,seed setting rate （SS） and 1 000-grain weight （1 000-GW）. These showed that PH,DS,FSP,SP and GWP were easily affected by sowing date and tended to higher with the later sowing; the RITSD of somaclonal changed with the agronomic traits. The frequency of RITSD＇ variation of DSH and PH was higher than that of PL. The RITSD＇ value of EP,PL,DS,FSP,SP and SS became higher,and higher or lower for DSH and GWP in different somaclonal; compared with the donor,20 of 24 was significantly different,and the frequency of RITSD variation was over 83. 3%,however,RITSD of the most lines （75%） changed only for 1-2 characters; cluster analysis showed that the RITSD of agronomic traits belonged to different combinations of somaclonal in rice. [Conclusion]the study had provided a theoretical basis for the screening and using of the somaclonal.
基金supported by the Chinese Natural Science Foundation Project (Grant No. 30970784 and 81171455)a National Distinguished Young Scholars Grant (Grant No. 31225009) from the National Natural Science Foundation of China+5 种基金the National Key Basic Research Program of China (Grant No. 2009CB930200)the Chinese Academy of Sciences (CAS) ‘Hundred Talents Program’ (Grant No. 07165111ZX)the CAS Knowledge Innovation Program, and the State HighTech Development Plan (Grant No. 2012AA020804)the ‘Strategic Priority Research Program’ of the Chinese Academy of Sciences (Grant No. XDA09030301)NIH/NIMHD 8 G12 MD007597USAMRMC W81XWH-10-1-0767 grants
文摘In the fight against cancer, controlled drug delivery systems have emerged to enhance the therapeutic efficacy and safety of anti-cancer drugs. Among these systems, mesoporous silica nanoparticles （MSNs） with a functional surface possess obvious advantages and were thus rapidly developed for cancer treatment. Many stimuli-responsive materials, such as nanopartides, polymers, and inorganic materials, have been applied as caps and gatekeepers to control drug release from MSNs. This review presents an overview of the recent progress in the production of pH-responsive MSNs based on the pH gradient between normal tissues and the tumor microenvironment. Four main categories of gatekeepers can respond to acidic conditions. These categories will be described in detail.
基金supported in part by the National Natural Science Foundation under grant No.U1533107the Major Program of Natural Science Foundation of Tianjin under grant No.17JCZDJC30900+1 种基金the Fundamental Research Funds for the Central Universities of CAUC under grant No.3122016D003the graduate program of curriculum development project of Civil Aviation University of China(2050070515)
文摘In frequency domain,the power spectrum of Low-rate denial of service(LDoS) attacks is totally spread into the spectrum of normal traffic.It is a challenging task to detect and filter LDoS attack flows from the normal traffic.Based on the analysis of LDoS attack flows and legitimate TCP traffic in time and frequency domains,the periodicity of the TCP traffic and LDoS attack flows is explored to facilitate the research of network traffic processing.Hence,an approach of LDoS attack flow filtering based on frequency spectrum analysis is proposed.In this approach,the TCP traffic and LDoS attack flows are transformed from the time domain into the frequency domain.Then the round-trip time(RTT) is estimated by using frequency domain search method.Analysis of amplitude spectrum shows that TCP traffic energy is mainly concentrated on the points of n/RTT.Therefore,a comb filter using infinite impulse response(IIR) filter is designed to filter out the LDoS attack flows in frequency domain,while most legitimate TCP traffic energy at the points of n/RTT are pass through.Experimental results show that the maximum pass rate for legitimate TCP traffic reaches 92.55%,while the maximum filtration rate of LDoS attack flows reaches 81.36%.The proposed approach can effectively filter the LDoS attack flows while less impact on the legitimate TCP traffic.
文摘A new sub-nanosecond pulse generator scheme is proposed in the opinion of frequency field in this paper. The filtering techniques used in the UWB (ultra-wideband) generator make the circuit simple and suitable for integration. The theoretical analysis and simulation results show that monocycle form generated in the scheme have a good balance between positive and negative shape and small traipse by circuit parameter control and has improved the quality of UWB pulse form.
