Significant progress has been made in the formulation of the functional nanomaterials with microemulsion phase.Microemulsion phase can be considered as true nanoreactors,which can be used to synthesize nanomaterials.P...Significant progress has been made in the formulation of the functional nanomaterials with microemulsion phase.Microemulsion phase can be considered as true nanoreactors,which can be used to synthesize nanomaterials.Properties and the mechanism of nanoparticle formation with microemulsion phase are reviewed in this paper.Preparation of the various nanomaterials,such as metal nanomaterials,oxide nanomaterials,magnetic nanoparticles,inorganic and inorganic compounds nanomaterials,metallic-organic composite nanomaterials,and other composite nanomaterials,are investigated with different microemulsion phases.The possible formation mechanisms are presented with the schematic diagram.展开更多
Individual inorganic nanoparticles （NPs） have been widely used in the fields of drug delivery, cancer imaging and therapy. There are still many hurdles that limit the performance of individual NPs for these applicat...Individual inorganic nanoparticles （NPs） have been widely used in the fields of drug delivery, cancer imaging and therapy. There are still many hurdles that limit the performance of individual NPs for these applications. The utilization of highly ordered NP ensembles opens a door to resolve these problems, as a result of their new or advanced collective properties. The assembled NPs show several advantages over individual NP-based systems, such as improved cell internalization and tumor targeting, enhanced multimodality imaging capability, superior combination therapy arising from synergistic effects, possible complete clearance from the whole body by degradation of assemblies into original small NP building blocks, and so on. In this review, we discuss the potential of utilizing assembled NP ensembles for cancer imaging and treatment by taking plasmonic vesicular assemblies of Au NPs as an example. We first summarize the recent developments in the self-assembly of plasmonic vesicular structures of NPs from amphiphilic polymer-tethered NP building blocks. We further review the utilization of plasmonic vesicles of NPs for cancer imaging （e.g. multi-photon induced luminescence, photothermal, and photoacoustic imaging）, and cancer therapy （e.g., photothermal therapy, and chemotherapy）. Finally, we outline current challenges and our perspectives along this line.展开更多
文摘Significant progress has been made in the formulation of the functional nanomaterials with microemulsion phase.Microemulsion phase can be considered as true nanoreactors,which can be used to synthesize nanomaterials.Properties and the mechanism of nanoparticle formation with microemulsion phase are reviewed in this paper.Preparation of the various nanomaterials,such as metal nanomaterials,oxide nanomaterials,magnetic nanoparticles,inorganic and inorganic compounds nanomaterials,metallic-organic composite nanomaterials,and other composite nanomaterials,are investigated with different microemulsion phases.The possible formation mechanisms are presented with the schematic diagram.
文摘Individual inorganic nanoparticles （NPs） have been widely used in the fields of drug delivery, cancer imaging and therapy. There are still many hurdles that limit the performance of individual NPs for these applications. The utilization of highly ordered NP ensembles opens a door to resolve these problems, as a result of their new or advanced collective properties. The assembled NPs show several advantages over individual NP-based systems, such as improved cell internalization and tumor targeting, enhanced multimodality imaging capability, superior combination therapy arising from synergistic effects, possible complete clearance from the whole body by degradation of assemblies into original small NP building blocks, and so on. In this review, we discuss the potential of utilizing assembled NP ensembles for cancer imaging and treatment by taking plasmonic vesicular assemblies of Au NPs as an example. We first summarize the recent developments in the self-assembly of plasmonic vesicular structures of NPs from amphiphilic polymer-tethered NP building blocks. We further review the utilization of plasmonic vesicles of NPs for cancer imaging （e.g. multi-photon induced luminescence, photothermal, and photoacoustic imaging）, and cancer therapy （e.g., photothermal therapy, and chemotherapy）. Finally, we outline current challenges and our perspectives along this line.
