Analysis of the safety and efficacy of the currently marked oral anticoagulants was performed in patients after large joints arthroplasty. A total of 5025 patients after total knee arthroplasty and 5216 patients after...Analysis of the safety and efficacy of the currently marked oral anticoagulants was performed in patients after large joints arthroplasty. A total of 5025 patients after total knee arthroplasty and 5216 patients after total hip arthroplasty were examined. All patients were divided into groups by the prescribed anticoagulant. The duration of anticoagulant therapy was 35 days and 6 weeks after surgery, respectively. Ultrasonography of the lower extremities veins was performed in all patients prior to the surgery and 5 days after surgery. In patients receiving Dabigatran, the incidence of clinically significant deep vein thrombosis was lower compared with patients receiving Rivaroxaban and Apixaban; in contrast, the rate of postoperative hematomas in the last two groups was higher.展开更多
Objective： To evaluate the clinical application of the medial approach for repairing popliteal artery injuries. Methods： From 2002 to 2008, 11 cases ofpopliteal artery injuries had been repaired via the medial appr...Objective： To evaluate the clinical application of the medial approach for repairing popliteal artery injuries. Methods： From 2002 to 2008, 11 cases ofpopliteal artery injuries had been repaired via the medial approach. Of these cases, 8 had limb fractures, 1 had knee dislocation, and 2 had visceral injuries. Ten popliteal arteries were anastomosed directly while one was repaired with a great saphenous vein graft. Results： The operation time ranged from 3 to 4 hours （averaging 3.6 hours）. All the injured limbs survived. At the follow up, 8 legs recovered the full function, 2 had minor contracture, and 1 serious Volkmann＇s contracture without amputation. Conclusion： The medial approach for repair of the popliteal artery is effective, applicable, and more advantageous to the management of multi-injures.展开更多
OBJECTIVE:To observe the influence of different moxibustion durations on hypothalamic pro-opiomelanocortin(POMC)and prodynorphin(PDYN)mRNA expressions and plasmaβ-endorphin(β-EP)content in rheumatoid arthritis(RA)ra...OBJECTIVE:To observe the influence of different moxibustion durations on hypothalamic pro-opiomelanocortin(POMC)and prodynorphin(PDYN)mRNA expressions and plasmaβ-endorphin(β-EP)content in rheumatoid arthritis(RA)rats,to understand the mechanism of moxibustion analgesia and its dose-effect relationship.METHODS:Twelve male Wistar rats were randomly selected from 48 male Wistar rats as a normal control group.The RA model was created by raising rats in a windy(blowing with electric fan),cold(6℃±2℃),and wet(80%-90%humidity)environment for 20 days,12 h each day.This was followed byinjectionofFreund'scompleteadjuvant(0.15 mL)into the ankle.Then,rats were randomly divided into a model group,moxibustion groupⅠ,and moxibustion groupⅡ,with 12 rats in each group.In moxibustion groupsⅠandⅡ,moxibustion was given at Shenshu(BL 23)and Zusanli(ST 36)for 20and 40 min,respectively,once daily for 15 days.Hypothalamic POMC and PDYN mRNA expression levels and plasmaβ-EP content were determined.RESULTS:Compared with the normal group,the pressure pain threshold decreased,while the hypothalamic POMC and PDYN mRNA expression levels and plasmaβ-EP content increased in the moxibustion groups(P<0.01).Compared with the model group,the pressure pain threshold,hypothalamic POMC and PDYN mRNA expression levels and plasmaβ-EP content in the moxibustion groups increased significantly(P<0.01).Compared the moxibustion groupⅠ,the pain threshold,hypothalamic POMC and PDYN mRNA expression levels and plasmaβ-EP content in moxibustion groupⅡsignificantly increased(P<0.01).CONCLUSION:Moxibustion has an analgesic effect and increases hypothalamic POMC and PDYN mRNA expression levels and plasmaβ-EP content inRArats.TheanalgesiceffectinmoxibustiongroupⅡisbetterthanthatinmoxibustiongroupⅠ.展开更多
Objective： One of the most common joint dislocations presented to the emergency department （ED） is anterior shoulder dislocation （ASD）. Various techniques for the treatment of this abnormality have been suggested...Objective： One of the most common joint dislocations presented to the emergency department （ED） is anterior shoulder dislocation （ASD）. Various techniques for the treatment of this abnormality have been suggested. In this study, we evaluated the efficacy and success rate of modified scapular manipulation （MSM） as a painless procedure compared to traction-countertraction （TCT） for reduction of ASD. Methods： Patients with ASD who were presented to ED of Baqiyatallah Hospital, Tehran during 2011 were included. They were randomly divided into MSM group or TCT group and then pain at reduction, time of reduction, duration of hospitalization, and success rate were compared. In TCT group, reduction was performed using sedative and antipain medications. Results： Ninety seven patients （81.6% male） with a mean age of 34.15 years±13.48 years were studied. The reduction time between both groups showed a significant difference （470.88 seconds±227.59 seconds for TCT group, 79.35 seconds±82.49 seconds for MSM group, P〈0.001）. The success rate in MSM group in the first and second effort were 89% and 97% whereas 73% and 100% in the TCT group respectively （P〈0.001）. Conclusion： It seems that the manipulation technique can be more successful than the TCT method at the first effort whilst the second effort has the opposite results. Also MSM can be safer, cheaper and more acceptable for patients than TCT as a standard traditional method.展开更多
文摘Analysis of the safety and efficacy of the currently marked oral anticoagulants was performed in patients after large joints arthroplasty. A total of 5025 patients after total knee arthroplasty and 5216 patients after total hip arthroplasty were examined. All patients were divided into groups by the prescribed anticoagulant. The duration of anticoagulant therapy was 35 days and 6 weeks after surgery, respectively. Ultrasonography of the lower extremities veins was performed in all patients prior to the surgery and 5 days after surgery. In patients receiving Dabigatran, the incidence of clinically significant deep vein thrombosis was lower compared with patients receiving Rivaroxaban and Apixaban; in contrast, the rate of postoperative hematomas in the last two groups was higher.
文摘Objective： To evaluate the clinical application of the medial approach for repairing popliteal artery injuries. Methods： From 2002 to 2008, 11 cases ofpopliteal artery injuries had been repaired via the medial approach. Of these cases, 8 had limb fractures, 1 had knee dislocation, and 2 had visceral injuries. Ten popliteal arteries were anastomosed directly while one was repaired with a great saphenous vein graft. Results： The operation time ranged from 3 to 4 hours （averaging 3.6 hours）. All the injured limbs survived. At the follow up, 8 legs recovered the full function, 2 had minor contracture, and 1 serious Volkmann＇s contracture without amputation. Conclusion： The medial approach for repair of the popliteal artery is effective, applicable, and more advantageous to the management of multi-injures.
基金Supported by 973 Program:the Research of Law and Principle of Moxibustion(No.2009CB522905)
文摘OBJECTIVE:To observe the influence of different moxibustion durations on hypothalamic pro-opiomelanocortin(POMC)and prodynorphin(PDYN)mRNA expressions and plasmaβ-endorphin(β-EP)content in rheumatoid arthritis(RA)rats,to understand the mechanism of moxibustion analgesia and its dose-effect relationship.METHODS:Twelve male Wistar rats were randomly selected from 48 male Wistar rats as a normal control group.The RA model was created by raising rats in a windy(blowing with electric fan),cold(6℃±2℃),and wet(80%-90%humidity)environment for 20 days,12 h each day.This was followed byinjectionofFreund'scompleteadjuvant(0.15 mL)into the ankle.Then,rats were randomly divided into a model group,moxibustion groupⅠ,and moxibustion groupⅡ,with 12 rats in each group.In moxibustion groupsⅠandⅡ,moxibustion was given at Shenshu(BL 23)and Zusanli(ST 36)for 20and 40 min,respectively,once daily for 15 days.Hypothalamic POMC and PDYN mRNA expression levels and plasmaβ-EP content were determined.RESULTS:Compared with the normal group,the pressure pain threshold decreased,while the hypothalamic POMC and PDYN mRNA expression levels and plasmaβ-EP content increased in the moxibustion groups(P<0.01).Compared with the model group,the pressure pain threshold,hypothalamic POMC and PDYN mRNA expression levels and plasmaβ-EP content in the moxibustion groups increased significantly(P<0.01).Compared the moxibustion groupⅠ,the pain threshold,hypothalamic POMC and PDYN mRNA expression levels and plasmaβ-EP content in moxibustion groupⅡsignificantly increased(P<0.01).CONCLUSION:Moxibustion has an analgesic effect and increases hypothalamic POMC and PDYN mRNA expression levels and plasmaβ-EP content inRArats.TheanalgesiceffectinmoxibustiongroupⅡisbetterthanthatinmoxibustiongroupⅠ.
文摘Objective： One of the most common joint dislocations presented to the emergency department （ED） is anterior shoulder dislocation （ASD）. Various techniques for the treatment of this abnormality have been suggested. In this study, we evaluated the efficacy and success rate of modified scapular manipulation （MSM） as a painless procedure compared to traction-countertraction （TCT） for reduction of ASD. Methods： Patients with ASD who were presented to ED of Baqiyatallah Hospital, Tehran during 2011 were included. They were randomly divided into MSM group or TCT group and then pain at reduction, time of reduction, duration of hospitalization, and success rate were compared. In TCT group, reduction was performed using sedative and antipain medications. Results： Ninety seven patients （81.6% male） with a mean age of 34.15 years±13.48 years were studied. The reduction time between both groups showed a significant difference （470.88 seconds±227.59 seconds for TCT group, 79.35 seconds±82.49 seconds for MSM group, P〈0.001）. The success rate in MSM group in the first and second effort were 89% and 97% whereas 73% and 100% in the TCT group respectively （P〈0.001）. Conclusion： It seems that the manipulation technique can be more successful than the TCT method at the first effort whilst the second effort has the opposite results. Also MSM can be safer, cheaper and more acceptable for patients than TCT as a standard traditional method.
