AIM:To evaluate survival and recurrence after salvage liver transplantation(SLT) for the treatment of hepatocellular carcinoma(HCC) compared with primary liver transplantation(PLT) using a meta-analysis.METHODS:Litera...AIM:To evaluate survival and recurrence after salvage liver transplantation(SLT) for the treatment of hepatocellular carcinoma(HCC) compared with primary liver transplantation(PLT) using a meta-analysis.METHODS:Literature on SLT versus PLT for the treatment of HCC published between 1966 and July 2011 was retrieved.A meta-analysis was conducted to estimate pooled survival and disease-free rates.A fixed or random-effect model was established to collect the data.RESULTS:The differences in overall survival and disease-free survival rates at 1-year,3-year and 5-year survival rates were not statistically significant between SLT group and PLT group(P > 0.05).After stratifying the various studies by donor source and Milan criteria,we found that:(1) Living donor liver transplantation recipients had significantly higher 1-year survival rate,lower 3-year and 5-year survival rates compared with deceased-donor liver transplantation(DDLT) recipients.And in DDLT recipients they had better 1-year and 5-year disease-free survival rate in SLT group;and(2) No difference was seen in 1-year,3-year and 5-year survival rates between two groups who beyond Milan criteria at the time of liver transplantation.CONCLUSION:SLT can be effectively performed for patients with recurrence or deterioration of liver function after hepatectomy for HCC.It does not increase the perioperative mortality and has a similar long-term survival rates compared to PLT.展开更多
Since different underground engineering contains different geological conditions,structure and excavation methods,their disturbing degree on the ground also differs,but ground surface settlement caused by excavation h...Since different underground engineering contains different geological conditions,structure and excavation methods,their disturbing degree on the ground also differs,but ground surface settlement caused by excavation has one common point that they will form a ground surface settlement curve.Based on data statistical analysis,the article puts forward the relationship between point of inflection in digging tunnels with shallowburied method and the span of tunnel excavation against typical geological conditions in Changchun so as to predict the impact of tunnel excavation and improve reasonable ground surface settlement control standard.Research result will be useful for study on ground surface control standard in digging tunnels with shallow-buried method and setting settlement standard.展开更多
文摘AIM:To evaluate survival and recurrence after salvage liver transplantation(SLT) for the treatment of hepatocellular carcinoma(HCC) compared with primary liver transplantation(PLT) using a meta-analysis.METHODS:Literature on SLT versus PLT for the treatment of HCC published between 1966 and July 2011 was retrieved.A meta-analysis was conducted to estimate pooled survival and disease-free rates.A fixed or random-effect model was established to collect the data.RESULTS:The differences in overall survival and disease-free survival rates at 1-year,3-year and 5-year survival rates were not statistically significant between SLT group and PLT group(P > 0.05).After stratifying the various studies by donor source and Milan criteria,we found that:(1) Living donor liver transplantation recipients had significantly higher 1-year survival rate,lower 3-year and 5-year survival rates compared with deceased-donor liver transplantation(DDLT) recipients.And in DDLT recipients they had better 1-year and 5-year disease-free survival rate in SLT group;and(2) No difference was seen in 1-year,3-year and 5-year survival rates between two groups who beyond Milan criteria at the time of liver transplantation.CONCLUSION:SLT can be effectively performed for patients with recurrence or deterioration of liver function after hepatectomy for HCC.It does not increase the perioperative mortality and has a similar long-term survival rates compared to PLT.
文摘Since different underground engineering contains different geological conditions,structure and excavation methods,their disturbing degree on the ground also differs,but ground surface settlement caused by excavation has one common point that they will form a ground surface settlement curve.Based on data statistical analysis,the article puts forward the relationship between point of inflection in digging tunnels with shallowburied method and the span of tunnel excavation against typical geological conditions in Changchun so as to predict the impact of tunnel excavation and improve reasonable ground surface settlement control standard.Research result will be useful for study on ground surface control standard in digging tunnels with shallow-buried method and setting settlement standard.
