The captopril/Chitosan-gelatin net-polymer microspheres(CTP/CGNPMs) were prepared using Chitosan(CTS) and gelatin(GT) by the methods of emulsification,cross-linked reagent alone or in combination and microcrystalline ...The captopril/Chitosan-gelatin net-polymer microspheres(CTP/CGNPMs) were prepared using Chitosan(CTS) and gelatin(GT) by the methods of emulsification,cross-linked reagent alone or in combination and microcrystalline cellulose(MCC) added in the process of preparation of microspheres,which aimed to eliminate dose dumping and burst phenomenon of microspheres for the improvement of the therapeutic efficiency and the decrease of the side effects of captopril(CTP). The results indicated that CTP/CGNPMs had a spherical shape,smooth surface and integral structure inside but no adhesive phenomena in the preparation. The size distribution ranged from 220 μm to 280 μm. The CTP release test in vitro demonstrated that CTP/CGNPMs played the role of retarding the release of CTP compared with ordinary CTP tablets. The release behaviors of CGNPMS were influenced by preparation conditions such as experimental material ratio(EMR) and composition of cross linking reagents. Among these factors,the EMR(1/4),CLR(FA+SPP) and 0.75% microcrystalline cellulose(MCC) added to the microspheres constituted the optimal scheme for the preparation of CTP/CGNPMs. The ER,DL and SR of CTP/CGNPMs prepared according to the optimal scheme were 46.23±4.51%,9.95±0.77% and 261±42%,respectively. The CTP/CGNPMs had the good characteristics of sustained release of drug and the process of emulsification and cross-linking were simple and stable. The CGNPMs are likely to be an ideal sustained release formulation for water-soluble drugs.展开更多
The waste dump of open-pit coal mine is remade of soil-rock mixture under the action of gravity,dynamic load of transportation equipment and earthquake,etc.By using artificial synthetic transparent soil,the developing...The waste dump of open-pit coal mine is remade of soil-rock mixture under the action of gravity,dynamic load of transportation equipment and earthquake,etc.By using artificial synthetic transparent soil,the developing process and migration law for soil-rock mixture are observed in the remade process.The mixture of fused quartz sand,liquid paraffin and n-tridecane is chosen as the material for synthetic transparent soil which is mixed with liquid paraffin and n-tridecane at a mass ratio of4.4at room temperature of17℃.Physical and mechanical properties of transparent soil are determined by physical test and compared with those in natural sandy soil.The results show that transparent soil and sandy soil have high similarity,in other words,transparent soil can be used for similar simulation experiments of soil-rock mixture.展开更多
Nowadays, lighting design is the modern attractive field of professional activity. Although its theoretical and methodological bases are in the initial stage of formulation. Though there are standards for regulating i...Nowadays, lighting design is the modern attractive field of professional activity. Although its theoretical and methodological bases are in the initial stage of formulation. Though there are standards for regulating illumination quantitatively, the science has never created a bridge to transfer illumination quantity into illumination quality. How to keep a day image of architectural object without imitating natural lighting？ How unrecognizably to change the image, to make it extraordinary and catchy？ This paper offers a solution in the form of external illumination designing principles. This paper proposes two conceptual ways of creating artificial lighting of buildings and constructions that pursue different goals： the principle of ＂tectonic＂ illumination and the principle of ＂decorative＂ illumination. These principles were developed based on the analysis of the state of the art experience of lighting architectural objects and author＇s empirical study. The latter contained measuring luminosity with luminance meter, processing the data, statistical survey （180 respondents） and lighting modeling in the laboratory of Moscow Architectural Institute.展开更多
We report Raman lasing and the optical analog of electromagnetically-induced-transparency(EIT) in a whispering-gallery-mode(WGM) microtoroid resonator embedded in a low refractive index polymer matrix together with a ...We report Raman lasing and the optical analog of electromagnetically-induced-transparency(EIT) in a whispering-gallery-mode(WGM) microtoroid resonator embedded in a low refractive index polymer matrix together with a tapered fiber coupler. The microtoroid resonator supports both single mode and multimode Raman lasing with low power thresholds. Observations of Fano and EIT-like phenomena in a packaged microresonator will enable high resolution sensors and can be used in networks where slow-light effect is needed. These results will open up new possibilities for portable, robust, and stable WGM microlasers and resonator-based sensors for applications in various environments.展开更多
＂Cultural feedback＂ （wenhua fanbu, literally ＂cultural reverse feeding＂）, an indigenous concept coined to facilitate the understanding of intergenerational relations in China＇s drastically changing society, foc...＂Cultural feedback＂ （wenhua fanbu, literally ＂cultural reverse feeding＂）, an indigenous concept coined to facilitate the understanding of intergenerational relations in China＇s drastically changing society, focuses on the subversion or reversal of conventional intergenerational relations in the light of changes triggered jointly by globalization and social transformation and views the extensive absorption of emerging cultural elements by the older generation from the young generation as a new mode of transmission. The process of the dissemination and selection of three kinds of modem artifacts-new foods, cell phones and computers--highlights the intergenerational tilt, the phenomenon of decentralization and the trend towards a digital divide. The subversion of conventional intergenerational relations in the process of the transmission of artifact civilization, as a significant part of Chinese psychological reactions to over three decades of reform and opening up, is indispensable to the psychological integrity of Chinese experience.展开更多
文摘The captopril/Chitosan-gelatin net-polymer microspheres(CTP/CGNPMs) were prepared using Chitosan(CTS) and gelatin(GT) by the methods of emulsification,cross-linked reagent alone or in combination and microcrystalline cellulose(MCC) added in the process of preparation of microspheres,which aimed to eliminate dose dumping and burst phenomenon of microspheres for the improvement of the therapeutic efficiency and the decrease of the side effects of captopril(CTP). The results indicated that CTP/CGNPMs had a spherical shape,smooth surface and integral structure inside but no adhesive phenomena in the preparation. The size distribution ranged from 220 μm to 280 μm. The CTP release test in vitro demonstrated that CTP/CGNPMs played the role of retarding the release of CTP compared with ordinary CTP tablets. The release behaviors of CGNPMS were influenced by preparation conditions such as experimental material ratio(EMR) and composition of cross linking reagents. Among these factors,the EMR(1/4),CLR(FA+SPP) and 0.75% microcrystalline cellulose(MCC) added to the microspheres constituted the optimal scheme for the preparation of CTP/CGNPMs. The ER,DL and SR of CTP/CGNPMs prepared according to the optimal scheme were 46.23±4.51%,9.95±0.77% and 261±42%,respectively. The CTP/CGNPMs had the good characteristics of sustained release of drug and the process of emulsification and cross-linking were simple and stable. The CGNPMs are likely to be an ideal sustained release formulation for water-soluble drugs.
基金Project(2015QNA40)supported by the Fundamental Research Funds for the Central Universities,China
文摘The waste dump of open-pit coal mine is remade of soil-rock mixture under the action of gravity,dynamic load of transportation equipment and earthquake,etc.By using artificial synthetic transparent soil,the developing process and migration law for soil-rock mixture are observed in the remade process.The mixture of fused quartz sand,liquid paraffin and n-tridecane is chosen as the material for synthetic transparent soil which is mixed with liquid paraffin and n-tridecane at a mass ratio of4.4at room temperature of17℃.Physical and mechanical properties of transparent soil are determined by physical test and compared with those in natural sandy soil.The results show that transparent soil and sandy soil have high similarity,in other words,transparent soil can be used for similar simulation experiments of soil-rock mixture.
文摘Nowadays, lighting design is the modern attractive field of professional activity. Although its theoretical and methodological bases are in the initial stage of formulation. Though there are standards for regulating illumination quantitatively, the science has never created a bridge to transfer illumination quantity into illumination quality. How to keep a day image of architectural object without imitating natural lighting？ How unrecognizably to change the image, to make it extraordinary and catchy？ This paper offers a solution in the form of external illumination designing principles. This paper proposes two conceptual ways of creating artificial lighting of buildings and constructions that pursue different goals： the principle of ＂tectonic＂ illumination and the principle of ＂decorative＂ illumination. These principles were developed based on the analysis of the state of the art experience of lighting architectural objects and author＇s empirical study. The latter contained measuring luminosity with luminance meter, processing the data, statistical survey （180 respondents） and lighting modeling in the laboratory of Moscow Architectural Institute.
基金supported by the US Army Research Office(ARO)(W911NF-12-1-0026 and W911NF1710189)
文摘We report Raman lasing and the optical analog of electromagnetically-induced-transparency(EIT) in a whispering-gallery-mode(WGM) microtoroid resonator embedded in a low refractive index polymer matrix together with a tapered fiber coupler. The microtoroid resonator supports both single mode and multimode Raman lasing with low power thresholds. Observations of Fano and EIT-like phenomena in a packaged microresonator will enable high resolution sensors and can be used in networks where slow-light effect is needed. These results will open up new possibilities for portable, robust, and stable WGM microlasers and resonator-based sensors for applications in various environments.
基金one of the results of "Chinese Experience in the Context of Globalization" which is sponsored by Nanjing University’s "Project 985," a reform project in the humanities and social sciences(Project No.: NJU985JD07)the "Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions"
文摘＂Cultural feedback＂ （wenhua fanbu, literally ＂cultural reverse feeding＂）, an indigenous concept coined to facilitate the understanding of intergenerational relations in China＇s drastically changing society, focuses on the subversion or reversal of conventional intergenerational relations in the light of changes triggered jointly by globalization and social transformation and views the extensive absorption of emerging cultural elements by the older generation from the young generation as a new mode of transmission. The process of the dissemination and selection of three kinds of modem artifacts-new foods, cell phones and computers--highlights the intergenerational tilt, the phenomenon of decentralization and the trend towards a digital divide. The subversion of conventional intergenerational relations in the process of the transmission of artifact civilization, as a significant part of Chinese psychological reactions to over three decades of reform and opening up, is indispensable to the psychological integrity of Chinese experience.
