CULTURAL and creative industries(CCI)are regarded as a positive force in promoting consumption,international trade,and employment,and also for strengthening social cohesion.This is because the CCI feature strong ind...CULTURAL and creative industries(CCI)are regarded as a positive force in promoting consumption,international trade,and employment,and also for strengthening social cohesion.This is because the CCI feature strong industrial integration,high added value,and are environment-friendly.展开更多
Floor diaphragms may provide an effective solution for reducing the seismic vulnerability of masonry buildings. Unfortunately, diaphragms are usually not present in historical building with wooden floors but often the...Floor diaphragms may provide an effective solution for reducing the seismic vulnerability of masonry buildings. Unfortunately, diaphragms are usually not present in historical building with wooden floors but often they are non present even in old R/C buildings where floors were made without shear reinforcement. A possible strengthening technique could be based on the application of a thin concrete plate reintbrced with a welded mesh. In order to reduce the thickness of the plate, some suitable solutions may be obtained by using Fiber Reinforced Concrete (FRC) since the minimum concrete cover is no longer required because the reinforcement (fibers) is spread all over the concrete matrix. The adoption of FRC floor diaphragms is proposed and discussed in this paper; the early results from a preliminary numerical study are analyzed in order to asses the feasibility of this new strengthening technique and better organize an experimental program that is currently in progress.展开更多
Objective: To investigate the association of XRCC4 polymorphic variants at G-1394T (rs6869366) with colorectal cancer susceptibility. Methods: In this hospital-based case-control study, the association of XRCC4 po...Objective: To investigate the association of XRCC4 polymorphic variants at G-1394T (rs6869366) with colorectal cancer susceptibility. Methods: In this hospital-based case-control study, the association of XRCC4 polymorphism with colorectal cancer risk in Chinese population was investigated. In total, 171 patients with colorectal cancer and 171 healthy individuals matched for age and gender were selected. The genomic DNAs of the patients and controls were extracted from peripheral blood and the 300 bp target DNA was amplified with Polymerase Chain Reaction. The products were then digested with restriction endonuclease HinclI, followed by agarose electrophoresis to identify the genotype. Results: We found a significant difference in the frequency of the XRCC4 G-1394T genotype between the colorectal cancer and control groups in female (1/127 vs 8/122, P〈0.05). Those with G/T at XRCC4 G-1394T showed a decreased risk of colorectal cancer susceptibility compared with those with T/T (OR 0.113, 95%CI 0.014-0.932). However, in overall population or in male, there was no significant difference of the distribution between the colorectal cancer and control groups. Conclusion: Our findings with decreased risk of colorectal cancer susceptibility suggested that the G allele of XRCC4 G-1394T were associated in female.展开更多
文摘CULTURAL and creative industries(CCI)are regarded as a positive force in promoting consumption,international trade,and employment,and also for strengthening social cohesion.This is because the CCI feature strong industrial integration,high added value,and are environment-friendly.
文摘Floor diaphragms may provide an effective solution for reducing the seismic vulnerability of masonry buildings. Unfortunately, diaphragms are usually not present in historical building with wooden floors but often they are non present even in old R/C buildings where floors were made without shear reinforcement. A possible strengthening technique could be based on the application of a thin concrete plate reintbrced with a welded mesh. In order to reduce the thickness of the plate, some suitable solutions may be obtained by using Fiber Reinforced Concrete (FRC) since the minimum concrete cover is no longer required because the reinforcement (fibers) is spread all over the concrete matrix. The adoption of FRC floor diaphragms is proposed and discussed in this paper; the early results from a preliminary numerical study are analyzed in order to asses the feasibility of this new strengthening technique and better organize an experimental program that is currently in progress.
文摘Objective: To investigate the association of XRCC4 polymorphic variants at G-1394T (rs6869366) with colorectal cancer susceptibility. Methods: In this hospital-based case-control study, the association of XRCC4 polymorphism with colorectal cancer risk in Chinese population was investigated. In total, 171 patients with colorectal cancer and 171 healthy individuals matched for age and gender were selected. The genomic DNAs of the patients and controls were extracted from peripheral blood and the 300 bp target DNA was amplified with Polymerase Chain Reaction. The products were then digested with restriction endonuclease HinclI, followed by agarose electrophoresis to identify the genotype. Results: We found a significant difference in the frequency of the XRCC4 G-1394T genotype between the colorectal cancer and control groups in female (1/127 vs 8/122, P〈0.05). Those with G/T at XRCC4 G-1394T showed a decreased risk of colorectal cancer susceptibility compared with those with T/T (OR 0.113, 95%CI 0.014-0.932). However, in overall population or in male, there was no significant difference of the distribution between the colorectal cancer and control groups. Conclusion: Our findings with decreased risk of colorectal cancer susceptibility suggested that the G allele of XRCC4 G-1394T were associated in female.