Visualization of tumor angiogenesis can facilitate noninvasive evaluation of tumor vascular characteristics to supplement the conventional diagnostic imaging goals of depicting tumor location,size,and morphology.Hybri...Visualization of tumor angiogenesis can facilitate noninvasive evaluation of tumor vascular characteristics to supplement the conventional diagnostic imaging goals of depicting tumor location,size,and morphology.Hybrid imaging techniques combine anatomic [ultrasound,computed tomography(CT),and/or magnetic resonance imaging(MRI)] and molecular(single photon emission CT and positron emission tomography) imaging modalities.One example is real-time virtual sonography,which combines ultrasound(grayscale,colour Doppler,or dynamic contrast harmonic imaging) with contrast-enhanced CT/MRI.The benefits of fusion imaging include an increased diagnostic confidence,direct comparison of the lesions using different imaging modalities,more precise monitoring of interventional procedures,and reduced radiation exposure.展开更多
Objective： To discuss the biodistribution of ^99mTc-Ciprofloxacin （^99mTc-CPF） and its effectiveness of imaging in infection disease in mice. Methods： CPF was labeled with ^99mTc and its radiochemical purity and l...Objective： To discuss the biodistribution of ^99mTc-Ciprofloxacin （^99mTc-CPF） and its effectiveness of imaging in infection disease in mice. Methods： CPF was labeled with ^99mTc and its radiochemical purity and labeling rate were measured. Mice model of infection was established and the biodistribution of ^99m Tc-CPF in the model and whole-body scintigraphy were achieved. Results： ^99mTc-Ciprotech was stable within 6 hours at room temperature. The labeling rate of ^99mTc-CPF was over 90%. Most of radioactivity was cleared in liver and kidney, and the clearance from blood was rapid. Both biodistribution and imaging results showed a high uptake of ^99mTc-CPF in infection site. The infection tissue/normal tissue reached a peak as 4.30 at 4 h after injection. Condusion： ^99mTc-CPF is a sensitive radiopharmaceutical agent for scintigraphy of infection lesions, and it is easy to prepare.展开更多
This paper expounds upon the basic principle of scanning electron microscopy(SEM),the main features of image types,and different signals,and the applications and prospects in earth sciences research are reviewed.High-...This paper expounds upon the basic principle of scanning electron microscopy(SEM),the main features of image types,and different signals,and the applications and prospects in earth sciences research are reviewed.High-resolution field emission SEM allows observation and investigation of a very fine micro area in situ.Using low-vacuum mode SEM,geological insulating samples can be analyzed directly without coating,demonstrating the wide application prospect.Combined with backscatter detector(BSE),energy dispersal X-ray spectroscopy(EDS),cathodoluminescence spectrometry(CL),and electron back-scattering diffraction(EBSD),SEM can yield multiple types of information about geological samples at the same time,such as superficial microstructure,CL analysis,BSE image,component analysis,and crystal structure features.In this paper,we use examples to discuss the geological application of SEM.We stress that we should not only focus on the CL image analysis,but strengthen CL spectrum analyses of minerals.These results will effectively reveal the mineral crystal lattice defects and trace element composition and can help to reconstruct mineral growth conditions precisely.展开更多
基金Supported by Research Grant No. 570/2008,Entitled "Integrative Prediction Model of Malignant Transformation of Regeneration Lesions in Cirrhotic Liver Using Noninvasive Imaging Techniques,Immunohistochemical and Molecular Genetic Methods"Financed by the Romanian Ministry of EducationResearch-National Authority for Scientific Research (PN2-ID-PCE)
文摘Visualization of tumor angiogenesis can facilitate noninvasive evaluation of tumor vascular characteristics to supplement the conventional diagnostic imaging goals of depicting tumor location,size,and morphology.Hybrid imaging techniques combine anatomic [ultrasound,computed tomography(CT),and/or magnetic resonance imaging(MRI)] and molecular(single photon emission CT and positron emission tomography) imaging modalities.One example is real-time virtual sonography,which combines ultrasound(grayscale,colour Doppler,or dynamic contrast harmonic imaging) with contrast-enhanced CT/MRI.The benefits of fusion imaging include an increased diagnostic confidence,direct comparison of the lesions using different imaging modalities,more precise monitoring of interventional procedures,and reduced radiation exposure.
文摘Objective： To discuss the biodistribution of ^99mTc-Ciprofloxacin （^99mTc-CPF） and its effectiveness of imaging in infection disease in mice. Methods： CPF was labeled with ^99mTc and its radiochemical purity and labeling rate were measured. Mice model of infection was established and the biodistribution of ^99m Tc-CPF in the model and whole-body scintigraphy were achieved. Results： ^99mTc-Ciprotech was stable within 6 hours at room temperature. The labeling rate of ^99mTc-CPF was over 90%. Most of radioactivity was cleared in liver and kidney, and the clearance from blood was rapid. Both biodistribution and imaging results showed a high uptake of ^99mTc-CPF in infection site. The infection tissue/normal tissue reached a peak as 4.30 at 4 h after injection. Condusion： ^99mTc-CPF is a sensitive radiopharmaceutical agent for scintigraphy of infection lesions, and it is easy to prepare.
基金supported by the National Natural Science Foundation of China(Grant No.41402031)
文摘This paper expounds upon the basic principle of scanning electron microscopy(SEM),the main features of image types,and different signals,and the applications and prospects in earth sciences research are reviewed.High-resolution field emission SEM allows observation and investigation of a very fine micro area in situ.Using low-vacuum mode SEM,geological insulating samples can be analyzed directly without coating,demonstrating the wide application prospect.Combined with backscatter detector(BSE),energy dispersal X-ray spectroscopy(EDS),cathodoluminescence spectrometry(CL),and electron back-scattering diffraction(EBSD),SEM can yield multiple types of information about geological samples at the same time,such as superficial microstructure,CL analysis,BSE image,component analysis,and crystal structure features.In this paper,we use examples to discuss the geological application of SEM.We stress that we should not only focus on the CL image analysis,but strengthen CL spectrum analyses of minerals.These results will effectively reveal the mineral crystal lattice defects and trace element composition and can help to reconstruct mineral growth conditions precisely.
