目的:研究薄荷油β-环糊精包合物的最佳制备工艺。方法:用正交实验法研究配比、温度、时间三个因素对薄荷油β-环糊精包合物的饱和水溶液法的制备工艺的影响,考察包合物的收率,并用TLC、显微影像验证包合物的形成。结果:最佳的工艺条件...目的:研究薄荷油β-环糊精包合物的最佳制备工艺。方法:用正交实验法研究配比、温度、时间三个因素对薄荷油β-环糊精包合物的饱和水溶液法的制备工艺的影响,考察包合物的收率,并用TLC、显微影像验证包合物的形成。结果:最佳的工艺条件薄荷油2.5 m l,包合温度50℃,包合时间3.5 h。结论:此方法可用于制备薄荷油β-环糊精包合物。展开更多
A system for in vitro investigation of ultrasound contrast agent's enhancement effect is presented and evaluated. It includes the digital B-mode ultrasound scanner Belson3000A, the tissue-mimicking ultrasound phantom...A system for in vitro investigation of ultrasound contrast agent's enhancement effect is presented and evaluated. It includes the digital B-mode ultrasound scanner Belson3000A, the tissue-mimicking ultrasound phantoms and the software which is used for image quantitative analysis. The linear range, optimal settings and repeatability of the system are assessed and explored by scanning the ultrasound phantoms with different reflective intensities. The measurements are performed under an acoustic power from 4.8 to 12.3 mW, the scanner centre frequency is 3.5 MH and the gain setting is 50 dB. Both a self-made surfactant encapsulated microbubble and a commercial ultrasound contrast agent are scanned. The results show that the pixel intensity of ultrasonic images increases with the increase in the sound power, and for the stronger reflective phantoms of more particles, the increasing trend is much more evident. The system is optimal for evaluating the microbubble contrast agents' enhancement effects. It presents a simple, effective and real-time means for characterizing the enhancement ability of microbubbles.展开更多
文摘目的:研究薄荷油β-环糊精包合物的最佳制备工艺。方法:用正交实验法研究配比、温度、时间三个因素对薄荷油β-环糊精包合物的饱和水溶液法的制备工艺的影响,考察包合物的收率,并用TLC、显微影像验证包合物的形成。结果:最佳的工艺条件薄荷油2.5 m l,包合温度50℃,包合时间3.5 h。结论:此方法可用于制备薄荷油β-环糊精包合物。
基金The National Basic Research Program of China (973Program) (No.2006CB933206)the National Natural Science Foundation of China(No.50872021,60725101)
文摘A system for in vitro investigation of ultrasound contrast agent's enhancement effect is presented and evaluated. It includes the digital B-mode ultrasound scanner Belson3000A, the tissue-mimicking ultrasound phantoms and the software which is used for image quantitative analysis. The linear range, optimal settings and repeatability of the system are assessed and explored by scanning the ultrasound phantoms with different reflective intensities. The measurements are performed under an acoustic power from 4.8 to 12.3 mW, the scanner centre frequency is 3.5 MH and the gain setting is 50 dB. Both a self-made surfactant encapsulated microbubble and a commercial ultrasound contrast agent are scanned. The results show that the pixel intensity of ultrasonic images increases with the increase in the sound power, and for the stronger reflective phantoms of more particles, the increasing trend is much more evident. The system is optimal for evaluating the microbubble contrast agents' enhancement effects. It presents a simple, effective and real-time means for characterizing the enhancement ability of microbubbles.