褥式血管吻合在手指钝性离断伤微创再植术中的应用分析

目的:探讨褥式血管吻合在手指钝性离断伤微创再植术中的应用分析。方法:回顾性分析本院2020年4月至2021年4月期间骨科手外显微骨三科收治的112例手指钝性离断伤患者,根据不同手术方法,将其分为单人褥式缝合组58例,双人褥式缝合组54例。比较两组患者手术时间、住院费用,并对所有患者进行术后6个月随访,参照英国医学会标准统计患指感觉、手指屈伸功能恢复情况(TAM)与患指成活率,对比两种缝合方式术后患指功能恢复优良率。结果:双人褥式缝合组患者手术时间短于单人褥式缝合组,住院费用少于单人褥式缝合组,差异有统计学意义(P<0.05);术后断指再植单人褥式缝合组成活55例,成活率94.83%,双人褥式缝合组成活52例,成活率96.30%,差异无统计学意义(P>0.05);术后感觉恢复:单人褥式缝合组优良率为82.76%,双人褥式缝合组优良率为93.34%,无显著差异(χ2=0.141,P=0.707);术后6个月参照TAM标准手指恢复情况中,两种褥式血管吻合方式TAM差异无统计学意义(P>0.05)。结论:在手指钝性离断伤微创再植术采用褥式血管吻合质量可靠,效果良好,尤其适用于双人褥式血管吻合,能缩短手术时间,减少患者住院费用,在手外显微外科或者创伤骨科方面有实际推广意义。

Detection and treatment of synchronous lesions in colorectal cancer: The clinical implication of perioperative colonoscopy

AIM： To evaluate the clinical significance of preand intra-operative colonoscopy for the detection of synchronous lesions in colon cancer.METHODS： Two hundred and sixty-five pre-operative and 51 intra-operative colonoscopic evaluations were performed in 316 colorectal cancer patients who underwent curative resection from January 2001 to June 2006. The incidence and characteristics of synchronous lesions and their influence on surgery were evaluated.RESULTS： Two hundred and eighty-two synchronous lesions were detected in 124 （39.2%） of 316 patients including all lesions regardless of their histologic type. True adenomatous polyps were found in 91 （28.8%） of 326 patients, and 27 （5.4% of all patients） patients had synchronous colon cancers. The preoperative identification of synchronous lesions altered the planned surgery in 37 （14.0%） of 265 patients. In 18 patients among the surgically removed cases, the lesions were removed by extending the resection range. Further segmental resection or polypectomy through enterotomy was necessary in 29 patients. Nineteen （37.2%） of 52 intraoperative colonoscopy cases had synchronous lesions. Additional surgical procedures including segmental bowel resection and polypectomy with enterotomy were necessary in 7 （23.7%） of 52 intraoperative colonoscopy cases to remove the lesions.CONCLUSION： Synchronous colorectal polyps or cancer are frequent and their preoperative detection is important for optimal surgical planning and treatment. Intraoperative colonoscopy is a useful option in cases where a preoperative colonoscopy is not feasible.

Dermatofibrosarcoma protuberans: from translocation to targeted therapy

Dermatofibrosarcoma protuberans(DFSP), the most common dermal sarcoma, is a low-grade, slow growing fibroblastic malignant neoplasm that most frequently affects middle aged adults and is characterized by a high local recurrence rate and a low propensity for metastasis. Wide surgical resection or Mohs micrographic surgery(MMS) are the preferred approaches for localized disease, while radiation therapy is warranted for inoperable disease or for cases with positive margins where re-excision is not possible. DFSP is generally regarded as refractory to conventional chemotherapy. Treatment options for systemic disease were limited until the discovery of a unique translocation, t(17;22)(q22;q13)(COL1A1;PDGFB) found in a majority of cases. In recent years, imatinib, a PDGFβR, ABL and KIT inhibitor, has revolutionized systemic therapy in DFSP. In this review, we summarize the epidemiological, clinical, histological and genetic characteristics of DFSP and update the readers on its current management.

The microsurgical treatment of glomus tumor at the nail bed of the finger

Objective： To discuss the diagnosis and treatment of glomus tumor at the nail bed of the finger. Methods： The course and therapeutic outcome of 12 cases of glomus tumor which were resected and confirmed by histology examination were analyzed. Results：All cases were followed up for six months up to 2 years, no recurrences were observed, the shape of the nait was normal. Conclusion： Microsurgical treatment of glomus tumors of the nail bed is effective.

THE EFFECTS OF INJURIES IN THE EXTREMITIES ON HUMAN COAGULATION STATUS

Objective To investigate the changes of blood coagulation status and the safety of emergency microsurgery in patients with acute trauma to their extremities. Methods Forty seven patients with open injuries to the extremities were divided into 3 groups: in Group Ia (n=20), the patients presented with open injury to a single limb without traumatic shock and chest or head injuries, and they did not undergo microsurgery; while in Group Ib (n=13), an emergency microsurgery was done. In Group Ⅱ , the patients suffered from multiple compound fractures of the extremities with traumatic shock and chest or head injuries. The blood coagulation status of all the patients was evaluated by testing platelet count (PLC), platelet adhesiveness (PadT), serum antithrombin Ⅲ (AT- Ⅲ ), and D-dimer (D-Di) level. Results In Groups Ia and Ib, only PadT was increased and AT- Ⅲ declined preoperatively, then they returned to normal 24h postoperatively. In Group Ⅱ, at different periods after trauma, there was significant evidence of Pg and AT-Ⅲ decline accompanied by high increase of PadT and D-Di level; at 24h postoperatively, the mean values were 49.3% (PadT), 2.7mg/L (D-Di), 1..1g/L (Pg), and 69.1% (AT-Ⅲ), respectively. All these changes got significant difference (P<0.05) when compared with the normal value and those of Groups Ia and Ib, and did not completely return to normal even 72h after operation. Conclusion An emergency microsurgery could be safely performed in patients with ordinary open injuries to their limbs without traumatic shock, however it should be done with caution in cases of severe injuries with traumatic shock, because hypercoagulation status would follow in several hours after injuries. D-Di measurement may be used as a screening test to predict and assess hypercoagulation status more early after trauma.

轴型皮瓣再造阴道126例经验体会

目的 总结 6种皮瓣再造阴道的临床经验。 方法 应用下腹部皮瓣、脐旁皮瓣、小阴唇皮瓣、阴囊皮瓣、阴茎皮瓣和阴股沟皮瓣再造阴道 12 6例。 结果 下腹部皮瓣坏死 1例 ,其余皮瓣全部成活 ,阴茎皮瓣法发生阴道口狭窄 1例 ,阴股沟皮瓣法有 3例阴道变浅。 结论 阴股沟皮瓣法距受区最近 ,转移方便 ,皮瓣薄 ,血管神经分布丰富 ,再造的阴道柔软 ,弹性好 ,有会阴部感觉 ,供区极隐蔽并可直接缝合 。