An artificial neural network (ANN) model was developed for simulating and predicting critical dimension dc of glass forming alloys. A group of Zr-Al-Ni-Cu and Cu-Zr-Ti-Ni bulk metallic glasses were designed based on...An artificial neural network (ANN) model was developed for simulating and predicting critical dimension dc of glass forming alloys. A group of Zr-Al-Ni-Cu and Cu-Zr-Ti-Ni bulk metallic glasses were designed based on the dc and their de values were predicted by the ANN model. Zr-Al-Ni-Cu and Cu-Zr-Ti-Ni bulk metallic glasses were prepared by injecting into copper mold. The amorphous structures and the determination of the dc of as-cast alloys were ascertained using X-ray diffraction. The results show that the predicted de values of glass forming alloys are in agreement with the corresponding experimental values. Thus the developed ANN model is reliable and adequate for designing the composition and predicting the de of glass forming alloy.展开更多
In order to deeply understand the grain growth behaviors of Ni80A superalloy,a series of grain growth experiments were conducted at holding temperatures ranging from 1223 to 1423 K and holding time ranging from 0 to 3...In order to deeply understand the grain growth behaviors of Ni80A superalloy,a series of grain growth experiments were conducted at holding temperatures ranging from 1223 to 1423 K and holding time ranging from 0 to 3600 s.A back-propagation artificial neural network(BP-ANN)model and a Sellars model were solved based on the experimental data.The prediction and generalization capabilities of these two models were evaluated and compared on the basis of four statistical indicators.The results show that the solved BP-ANN model has better performance as it has higher correlation coefficient(r),lower average absolute relative error(AARE),lower absolute values of mean value(μ)and standard deviation(ω).Eventually,a response surface of average grain size to holding temperature and holding time is constructed based on the data expanded by the solved BP-ANN model,and the grain growth behaviors are described.展开更多
Objective To discover the pharmacological mechanisms of monotropein in colorectal cancer by network pharmacology methods.Methods The main-candidate-target network was constructed by the prediction of targets of monotr...Objective To discover the pharmacological mechanisms of monotropein in colorectal cancer by network pharmacology methods.Methods The main-candidate-target network was constructed by the prediction of targets of monotropein, collection of therapeutic targets of colorectal cancer drugs, and construction of the target network and layers of screening. The data were interpreted by pathway enrichment and target score calculation.Results This study:(1) Demonstrated the potential of monotropein to be a multi-target drug against colorectal cancer using a computational approach;(2) Discovered 10 candidate targets of monotropein, among which protein kinase B(AKT1)exhibited the highest relevance and importance to colorectal cancer and proto-oncogene tyrosine-protein kinase Src(SRC),Bruton’s tyrosine kinase(BTK), and heat shock protein HSP 90-alpha(HSP90 AA1) also exhibited high relevance;(3) Observed 32 possible pathways related to the effects of monotropein on colorectal cancer, which might explain the mechanism of its action;and(4) Established a method to assess the importance of targets in the network.Conclusions This study offered clues for the mechanism of the bioactivities of monotropein against colorectal cancer by network analysis. Monotropein has the potential to be a multi-target drug against colorectal cancer, which lays the foundation for its clinical applications and further study.展开更多
The closed form of solutions of Kac-van Moerbeke lattice and self-dual network equations are considered by proposing transformations based on Riccati equation, using symbolic computation. In contrast to the numerical ...The closed form of solutions of Kac-van Moerbeke lattice and self-dual network equations are considered by proposing transformations based on Riccati equation, using symbolic computation. In contrast to the numerical computation of travelling wave solutions for differential difference equations, our method obtains exact solutions which have physical relevance.展开更多
Lattice-valued logic plays an important role in multi-valued logic systems. A lattice valued logic system lp(X) is constructed. The syntax of lp(X) is discussed. It may be more convenient in application and study espe...Lattice-valued logic plays an important role in multi-valued logic systems. A lattice valued logic system lp(X) is constructed. The syntax of lp(X) is discussed. It may be more convenient in application and study especially in the case that the valuation domain is finite lattice implication algebra.展开更多
With the large-signal model extracted from the InGaP/GaAs HBT with three fingers,a three-stage,class AB power amplifier at ISM band is designed.Through the optimization of the traditional bias network,the gain compres...With the large-signal model extracted from the InGaP/GaAs HBT with three fingers,a three-stage,class AB power amplifier at ISM band is designed.Through the optimization of the traditional bias network,the gain compression at the low input power level is eliminated successfully.At 3.5V of supply voltage of the power amplifier after optimization exhibits 30dBm of maximum linear output power,43.4% of power added efficiency 109.7mA of a quite low quiescent bias current ,29.1dB of the corresponding gain,and -100dBc of the adjacent channel power rejection (ACPR) at the output power of 30dBm.展开更多
A neuro-space mapping(Neuro-SM) for modeling heterojunction bipolar transistor(HBT) is presented, which can automatically modify the input signals of the given model by neural network. The novel Neuro-SM formulations ...A neuro-space mapping(Neuro-SM) for modeling heterojunction bipolar transistor(HBT) is presented, which can automatically modify the input signals of the given model by neural network. The novel Neuro-SM formulations for DC and small-signal simulation are proposed to obtain the mapping network. Simulation results show that the errors between Neuro-SM models and the accurate data are less than 1%, demonstrating that the accurcy of the proposed method is higher than those of the existing models.展开更多
We investigate cooperative behaviors of lattice-embedded scale-free networking agents in the prisoner'sdilemma game model by employing two initial strategy distribution mechanisms,which are specific distribution t...We investigate cooperative behaviors of lattice-embedded scale-free networking agents in the prisoner'sdilemma game model by employing two initial strategy distribution mechanisms,which are specific distribution to themost connected sites (hubs) and random distribution.Our study indicates that the game dynamics crucially dependson the underlying spatial network structure with different strategy distribution mechanism.The cooperators' specificdistribution contributes to an enhanced level of cooperation in the system compared with random one,and cooperationis robust to cooperators' specific distribution but fragile to defectors' specific distribution.Especially,unlike the specificcase,increasing heterogeneity of network does not always favor the emergence of cooperation under random mechanism.Furthermore,we study the geographical effects and find that the graphically constrained network structure tends toimprove the evolution of cooperation in random case and in specific one for a large temptation to defect.展开更多
Wafer bin map(WBM)inspection is a critical approach for evaluating the semiconductor manufacturing process.An excellent inspection algorithm can improve the production efficiency and yield.This paper proposes a WBM de...Wafer bin map(WBM)inspection is a critical approach for evaluating the semiconductor manufacturing process.An excellent inspection algorithm can improve the production efficiency and yield.This paper proposes a WBM defect pattern inspection strategy based on the DenseNet deep learning model,the structure and training loss function are improved according to the characteristics of the WBM.In addition,a constrained mean filtering algorithm is proposed to filter the noise grains.In model prediction,an entropy-based Monte Carlo dropout algorithm is employed to quantify the uncertainty of the model decision.The experimental results show that the recognition ability of the improved DenseNet is better than that of traditional algorithms in terms of typical WBM defect patterns.Analyzing the model uncertainty can not only effectively reduce the miss or false detection rate but also help to identify new patterns.展开更多
First-principles calculations have been performed to investigate energetics and site preference of carbon (C) in a tungsten (W) 5(310)/[001] grain boundary (GB). We calculate the solution energies of the C atom in the...First-principles calculations have been performed to investigate energetics and site preference of carbon (C) in a tungsten (W) 5(310)/[001] grain boundary (GB). We calculate the solution energies of the C atom in the GB, which show that the interstitial C is energetically favored over the substitutional C. The segregation energy is calculated to be 3.95 eV for the energetically favorable GB interstitial site, indicating that C energetically prefers to segregate into the W GB. Based on the Rice-Wang model, our total energy calculations show that C has a significant beneficial effect on the W GB cohesion.展开更多
A new type of single-walled carbon nanotube (SWNT) thin-film transistor (TFT) structure with a nanomesh network channel has been fabricated from a pre- separated semiconducting nanotube solution and simultaneously...A new type of single-walled carbon nanotube (SWNT) thin-film transistor (TFT) structure with a nanomesh network channel has been fabricated from a pre- separated semiconducting nanotube solution and simultaneously achieved both high uniformity and a high on/off ratio for application in large-scale integrated circuits. The nanomesh structure is prepared on a high-density SWNT network channel and enables a high on/off ratio while maintaining the excellent uniformity of the electrical properties of the SWNT TFTs. These effects are attributed to the effective elimination of metallic paths across the source/drain electrodes by forming the nanomesh structure in the high-density SWNT network channel. Therefore, our approach can serve as a critical foundation for future nanotube-based thin- film display electronics.展开更多
Ultralong phosphorescent materials have numerous applications across biological imaging, lightemitting devices, X-ray detection and anti-counterfeiting. Triplet-state molecular phosphorescence typically accompanies th...Ultralong phosphorescent materials have numerous applications across biological imaging, lightemitting devices, X-ray detection and anti-counterfeiting. Triplet-state molecular phosphorescence typically accompanies the singlet-state fluorescence during photoluminescence, and it is still difficult to achieve direct triplet photoemission as ultralong room temperature phosphorescence(RTP). Here, we have designed Zn-IMDC(IMDC, 4,5-imidazoledicarboxylic acid) and Cd-IMDC, two-dimensional(2D)hydrogen-bond organized metal–organic crystalline microsheets that exhibit rarely direct ultralong RTP upon UV excitation, benefiting from the appropriate heavy-atom effect and multiple triplet energy levels. The excitation-dependent and thermally stimulated ultralong phosphorescence endow the metal–organic systems great opportunities for information safety application and temperature-gated afterglow emission. The well-defined 2D microsheets present color-tunable and anisotropic optical waveguides under different excitation and temperature conditions, providing an effective way to obtain intelligent RTP-based photonic systems at the micro-and nano-scales.展开更多
The geometrical matching/mismatching of lattices overlapped in 1, 2 and 3 dimensions have been analyzed systematically by variation of lattice misfit in a large range, far beyond the limits for semicoherent interfaces...The geometrical matching/mismatching of lattices overlapped in 1, 2 and 3 dimensions have been analyzed systematically by variation of lattice misfit in a large range, far beyond the limits for semicoherent interfaces. In order to evaluate the degree of matching, the density of good matching site (GMS) between two lattices is calculated. The analysis shows that the GMS density remains approximately constant, irrespectively to the degree of lattice misfit. This constant, defined as the average GMS density, decreases exponentially with the increasing dimension of misfit. Typically, for 6 = 15%, the average GMS densities are approximately 30%, 7%, and 1.4% for 1D, 2D, and 3D lattice misfits, respectively. The GMS density deviates significantly if a CSL of small X can be defined. The relationship between the GMS distribution and O-lattice is investigated. It indicates that an abrupt increase in the GMS density in an interface parallel to a principal O-lattice plane is equivalent to a reduction of dimension of misfit. This shows the agreement between the selections of principal O-lattice planes as candidates of the preferred interfaces and the condition that interfaces with high GMS density are preferred.展开更多
基金Project(50874045)supported by the National Natural Science Foundation of China
文摘An artificial neural network (ANN) model was developed for simulating and predicting critical dimension dc of glass forming alloys. A group of Zr-Al-Ni-Cu and Cu-Zr-Ti-Ni bulk metallic glasses were designed based on the dc and their de values were predicted by the ANN model. Zr-Al-Ni-Cu and Cu-Zr-Ti-Ni bulk metallic glasses were prepared by injecting into copper mold. The amorphous structures and the determination of the dc of as-cast alloys were ascertained using X-ray diffraction. The results show that the predicted de values of glass forming alloys are in agreement with the corresponding experimental values. Thus the developed ANN model is reliable and adequate for designing the composition and predicting the de of glass forming alloy.
基金Project(cstc2018jcyjAX0459)supported by Chongqing Basic Research and Frontier Exploration Program,ChinaProjects(2019CDQYTM027,2019CDJGFCL003)supported by the Fundamental Research Funds for the Central Universities,China。
文摘In order to deeply understand the grain growth behaviors of Ni80A superalloy,a series of grain growth experiments were conducted at holding temperatures ranging from 1223 to 1423 K and holding time ranging from 0 to 3600 s.A back-propagation artificial neural network(BP-ANN)model and a Sellars model were solved based on the experimental data.The prediction and generalization capabilities of these two models were evaluated and compared on the basis of four statistical indicators.The results show that the solved BP-ANN model has better performance as it has higher correlation coefficient(r),lower average absolute relative error(AARE),lower absolute values of mean value(μ)and standard deviation(ω).Eventually,a response surface of average grain size to holding temperature and holding time is constructed based on the data expanded by the solved BP-ANN model,and the grain growth behaviors are described.
基金the funding support from the Joint Research Fund for Overseas Chinese,Hong Kong and Macao Young Scholars of National Science Foundation of China(No.81929003)the Science and Technology Development Fund,Macao SAR(No.0027/2017/AMJ)the National Key Research and Development Program of China(No.2017YFE0119900).
文摘Objective To discover the pharmacological mechanisms of monotropein in colorectal cancer by network pharmacology methods.Methods The main-candidate-target network was constructed by the prediction of targets of monotropein, collection of therapeutic targets of colorectal cancer drugs, and construction of the target network and layers of screening. The data were interpreted by pathway enrichment and target score calculation.Results This study:(1) Demonstrated the potential of monotropein to be a multi-target drug against colorectal cancer using a computational approach;(2) Discovered 10 candidate targets of monotropein, among which protein kinase B(AKT1)exhibited the highest relevance and importance to colorectal cancer and proto-oncogene tyrosine-protein kinase Src(SRC),Bruton’s tyrosine kinase(BTK), and heat shock protein HSP 90-alpha(HSP90 AA1) also exhibited high relevance;(3) Observed 32 possible pathways related to the effects of monotropein on colorectal cancer, which might explain the mechanism of its action;and(4) Established a method to assess the importance of targets in the network.Conclusions This study offered clues for the mechanism of the bioactivities of monotropein against colorectal cancer by network analysis. Monotropein has the potential to be a multi-target drug against colorectal cancer, which lays the foundation for its clinical applications and further study.
基金The project supported by "973" Project under Grant No.2004CB318000, the Doctor Start-up Foundation of Liaoning Province of China under Grant No. 20041066, and the Science Research Plan of Liaoning Education Bureau under Grant No. 2004F099
文摘The closed form of solutions of Kac-van Moerbeke lattice and self-dual network equations are considered by proposing transformations based on Riccati equation, using symbolic computation. In contrast to the numerical computation of travelling wave solutions for differential difference equations, our method obtains exact solutions which have physical relevance.
基金The National Science Fund of China(No.60074014,60474022)The Project Fund of Zhejiang Science and Technology Depart ment,China(No.2005C31005)
文摘Lattice-valued logic plays an important role in multi-valued logic systems. A lattice valued logic system lp(X) is constructed. The syntax of lp(X) is discussed. It may be more convenient in application and study especially in the case that the valuation domain is finite lattice implication algebra.
文摘With the large-signal model extracted from the InGaP/GaAs HBT with three fingers,a three-stage,class AB power amplifier at ISM band is designed.Through the optimization of the traditional bias network,the gain compression at the low input power level is eliminated successfully.At 3.5V of supply voltage of the power amplifier after optimization exhibits 30dBm of maximum linear output power,43.4% of power added efficiency 109.7mA of a quite low quiescent bias current ,29.1dB of the corresponding gain,and -100dBc of the adjacent channel power rejection (ACPR) at the output power of 30dBm.
基金Supported by the National Natural Science Foundation of China(No.61271067)
文摘A neuro-space mapping(Neuro-SM) for modeling heterojunction bipolar transistor(HBT) is presented, which can automatically modify the input signals of the given model by neural network. The novel Neuro-SM formulations for DC and small-signal simulation are proposed to obtain the mapping network. Simulation results show that the errors between Neuro-SM models and the accurate data are less than 1%, demonstrating that the accurcy of the proposed method is higher than those of the existing models.
文摘We investigate cooperative behaviors of lattice-embedded scale-free networking agents in the prisoner'sdilemma game model by employing two initial strategy distribution mechanisms,which are specific distribution to themost connected sites (hubs) and random distribution.Our study indicates that the game dynamics crucially dependson the underlying spatial network structure with different strategy distribution mechanism.The cooperators' specificdistribution contributes to an enhanced level of cooperation in the system compared with random one,and cooperationis robust to cooperators' specific distribution but fragile to defectors' specific distribution.Especially,unlike the specificcase,increasing heterogeneity of network does not always favor the emergence of cooperation under random mechanism.Furthermore,we study the geographical effects and find that the graphically constrained network structure tends toimprove the evolution of cooperation in random case and in specific one for a large temptation to defect.
基金Project(Z135060009002)supported by the Ministry of Industry and Information Technology of ChinaProject(KZ202010005004)supported by Beijing Municipal Commission of Education and Beijing Municipal Natural Science Foundation of China。
文摘Wafer bin map(WBM)inspection is a critical approach for evaluating the semiconductor manufacturing process.An excellent inspection algorithm can improve the production efficiency and yield.This paper proposes a WBM defect pattern inspection strategy based on the DenseNet deep learning model,the structure and training loss function are improved according to the characteristics of the WBM.In addition,a constrained mean filtering algorithm is proposed to filter the noise grains.In model prediction,an entropy-based Monte Carlo dropout algorithm is employed to quantify the uncertainty of the model decision.The experimental results show that the recognition ability of the improved DenseNet is better than that of traditional algorithms in terms of typical WBM defect patterns.Analyzing the model uncertainty can not only effectively reduce the miss or false detection rate but also help to identify new patterns.
基金supported by the National Magnetic Confinement Fusion Program (Grant No.2009GB106003)the National Natural Science Foundation of China (Grant No.50871009)support of the Innovation Foundation of BUAA for PhD Graduates
文摘First-principles calculations have been performed to investigate energetics and site preference of carbon (C) in a tungsten (W) 5(310)/[001] grain boundary (GB). We calculate the solution energies of the C atom in the GB, which show that the interstitial C is energetically favored over the substitutional C. The segregation energy is calculated to be 3.95 eV for the energetically favorable GB interstitial site, indicating that C energetically prefers to segregate into the W GB. Based on the Rice-Wang model, our total energy calculations show that C has a significant beneficial effect on the W GB cohesion.
文摘A new type of single-walled carbon nanotube (SWNT) thin-film transistor (TFT) structure with a nanomesh network channel has been fabricated from a pre- separated semiconducting nanotube solution and simultaneously achieved both high uniformity and a high on/off ratio for application in large-scale integrated circuits. The nanomesh structure is prepared on a high-density SWNT network channel and enables a high on/off ratio while maintaining the excellent uniformity of the electrical properties of the SWNT TFTs. These effects are attributed to the effective elimination of metallic paths across the source/drain electrodes by forming the nanomesh structure in the high-density SWNT network channel. Therefore, our approach can serve as a critical foundation for future nanotube-based thin- film display electronics.
基金supported by the Beijing Municipal Natural Science Foundation(JQ20003)the National Natural Science Foundation of China(21771021,21822501,and 22061130206)+3 种基金the Fok Ying-Tong Education Foundation(171008)the Measurements Fund of Beijing Normal Universitythe State Key Laboratory of Heavy Oil Processing。
文摘Ultralong phosphorescent materials have numerous applications across biological imaging, lightemitting devices, X-ray detection and anti-counterfeiting. Triplet-state molecular phosphorescence typically accompanies the singlet-state fluorescence during photoluminescence, and it is still difficult to achieve direct triplet photoemission as ultralong room temperature phosphorescence(RTP). Here, we have designed Zn-IMDC(IMDC, 4,5-imidazoledicarboxylic acid) and Cd-IMDC, two-dimensional(2D)hydrogen-bond organized metal–organic crystalline microsheets that exhibit rarely direct ultralong RTP upon UV excitation, benefiting from the appropriate heavy-atom effect and multiple triplet energy levels. The excitation-dependent and thermally stimulated ultralong phosphorescence endow the metal–organic systems great opportunities for information safety application and temperature-gated afterglow emission. The well-defined 2D microsheets present color-tunable and anisotropic optical waveguides under different excitation and temperature conditions, providing an effective way to obtain intelligent RTP-based photonic systems at the micro-and nano-scales.
基金supported from the National Natural Science Foundation of China (Grant No. 1171088)the National Basic Research Program of China (Grant No. 12CB619403) from Chinese Ministry of Science and Technology
文摘The geometrical matching/mismatching of lattices overlapped in 1, 2 and 3 dimensions have been analyzed systematically by variation of lattice misfit in a large range, far beyond the limits for semicoherent interfaces. In order to evaluate the degree of matching, the density of good matching site (GMS) between two lattices is calculated. The analysis shows that the GMS density remains approximately constant, irrespectively to the degree of lattice misfit. This constant, defined as the average GMS density, decreases exponentially with the increasing dimension of misfit. Typically, for 6 = 15%, the average GMS densities are approximately 30%, 7%, and 1.4% for 1D, 2D, and 3D lattice misfits, respectively. The GMS density deviates significantly if a CSL of small X can be defined. The relationship between the GMS distribution and O-lattice is investigated. It indicates that an abrupt increase in the GMS density in an interface parallel to a principal O-lattice plane is equivalent to a reduction of dimension of misfit. This shows the agreement between the selections of principal O-lattice planes as candidates of the preferred interfaces and the condition that interfaces with high GMS density are preferred.