透明质酸钠与曲安奈得治疗颞下颌关节滑膜炎的对比观察

目的:探索治疗颞下颌关节继发性滑膜炎的方法。方法:选择颞下颌关节滑膜炎患者67例,随机分成2组,分别采用透明质酸钠和曲安奈得行关节腔注射治疗,对比2种药物的治疗效果,并计算各组总有效率并进行χ2检验。结果:治疗后1周、1、3月复诊,1周时2组有显著差异,曲安奈得好于透明质酸钠(P<0.05);1月时2组无明显差异(P>0.05);3月时2组又有显著差异,透明质酸钠好于曲安奈得(P<0.01)。结论:短期效果曲安奈得比透明质酸钠好,长期疗效透明质酸钠比曲安奈得好。

曲安奈得联合仙卡治疗瘢痕疙瘩101例疗效观察

目的探讨曲安奈得联合仙卡治疗瘢痕疙瘩的疗效。方法对我院收治的101例患者采用曲安奈得局部注射联合仙卡治疗瘢痕疙瘩,观察疗效。结果101例患者身体不同部位共分布123块瘢痕疙瘩病变,达到临床治愈标准的有72块,显效43块,无效8块,有效率(治愈+显效)达93.5%。痛痒症状在注药后3-5d内基本消失。结论曲安奈得联合仙卡治疗瘢痕疙瘩效果好、疗效可靠。

玻璃酸钠联合曲安奈得膝关节腔内注射治疗创伤性滑膜炎230例

膝关节创伤性滑膜炎为运动创伤中的常见病，它严重影响运动员训练和比赛。我们于2000年7月-2003年5月采用玻璃酸钠联合曲安奈得膝关节腔内注射治疗创伤性滑膜炎230例，效果满意，现报告如下。

曲安奈得局部注射治疗少年儿童眼眶血管瘤

目的探讨曲安奈得局部注射治疗少年儿童眼眶血管瘤的疗效。方法采用曲安奈得、地塞米松及利多卡因混合液在血管瘤内注射,2周1次,3次为一疗程。结果本组18例中,显效9例,有效4例,无效5例,总有效率为72.22%。结论曲安奈得局部注射治疗少年儿童眼眶血管瘤疗效较佳,不良反应小,临床应用方便。

曲安奈得注射治疗瘢痕疙瘩的临床疗效分析

目的探讨曲安奈得注射治疗瘢痕疙瘩的疗效。方法296例患者采用曲安奈得加利多卡因联合加压注射于瘢痕疙瘩内的疗效观察。结果296例患者治疗后疼痛瘙痒消除,瘢痕不同程度变平变软缩小,颜色变浅,随访1年无明显复发。结论采用曲安奈得注射治疗瘢痕疙瘩具有美容效果好、疗效可靠的优点。

5-氟尿嘧啶联合曲安奈得治疗翼状胬肉的护理配合

[目的 ]总结 96例 5 -氟尿嘧啶联合曲安奈得局部注射治疗翼状胬肉的疗效及护理配合。 [方法 ]采用 5 -氟尿嘧啶联合曲安奈得局部注射疗法。 [结果 ]总有效率为 91.67% ,显效率为 70 .83 %。 [结论 ] 5 -氟尿嘧啶联合曲安奈得局部注射对各型翼状胬肉都有较好的疗效 ,尤其适用于静止期胬肉 ,注射前注意完善检查 ,做好心理护理 ,注射过程中动作要轻 。

曲安奈得注射液在治疗第三腰椎横突综合征中的应用

目的观察分析曲安奈得注射液治疗第三腰椎横突综合征的疗效。方法对2006年6月～2008年6月92例第三腰椎横突综合征患者应用曲安奈得注射液治疗进行回顾性分析总结。结果运用曲安奈得注射液治疗第三腰椎横突综合征总有效率97.83%,且未发现并发症和副作用。结论曲安奈得局部注射治疗第三腰推横突综合征能达到简、便、廉、效的治疗结果,值得推广。

曲安奈得:用于玻璃体内注射的配制法

目的:具有抗增生、抗水肿、抗炎和血管稳定作用的曲安奈得(TA)混悬液在眼水肿、新生血管和增生性疾病,特别是黄斑疾病的应用正在不断增加。本文描述玻璃体内注射用的TA的配制法并分析赋形剂(苯甲基乙醇)过滤后的实际剂量。方法:从40mgVolonA瓶中,相当于Kenalog40mg,抽取0.625mL结晶混悬液,相当于TA25mg。在无菌条件下,过滤混悬液以去除溶剂苯甲基乙醇,结晶体用9g/L氯化钠洗涤4次,进行TA玻璃体注射。需要密切随访,监测在头2wk内的眼内炎和1￣2mo的高眼压。结果:预期25mgTA的浓度在溶剂过滤后测量为23.8mg。在另一个药学实验室,同样过滤后结果是12.8mg,均不是预期的剂量25mgTA。结论:还没有玻璃体内注射TA的标准剂量。手术医生应该知道过滤后玻璃体内注射TA的剂量将比预期的要少。需要在注射后密切随访:在第1wk监测无菌性眼内炎或假性眼内炎,在第2wk要识别感染性眼内炎,它可能出现在无痛和不充血的眼,但必须立即治疗。继发性高眼压可能在注射后1￣2mo发生;一般可用抗青光眼药物控制。

曲安奈得治疗前色素膜炎的临床观察

目的观察曲安奈得治疗前色素膜炎的临床效果。方法应用曲安奈得注射液20mg于患眼球结膜下注射,每半月1次,最多注射3次。同时予散瞳等治疗。结果治疗85例98眼,治愈76例87眼(88.8%),好转8例9眼(9.2%),无效1例2眼(2%)。无停药反跳现象及全身副作用和眼部并发症。结论曲安奈得结膜下注射治疗前色素膜炎疗效好,可明显减少结膜下注射及滴眼次数,防止皮质类固醇激素停药后的反跳现象,减少全身长期应用皮质类固醇的副作用。

曲安奈得配合针刀治疗弹响指26例临床疗效观察

弹响指又称扳机指,又称手指屈肌腱腱鞘炎,是腱鞘机械性摩擦而引起的慢性无菌性炎性改变。是门诊的常见病,多见于手工劳动者,以拇指、中指、环指最多见。主要为掌指关节掌侧局限性疼痛和手指活动受限,随腱鞘狭窄加重和肌腱受压呈葫芦状膨大,检查时可触及掌骨头局部结节物,手指屈伸时可感结节状物滑动,常因腱鞘狭窄而受阻,继续用力时可突然滑过,并伴有弹响或弹跳疼痛。

玻璃体腔注射曲安奈得后黄斑格栅光凝治疗弥漫性糖尿病性黄斑水肿

Objective:To evaluate the clinical outcomes of macular laser photocoagulation after the intravitreal injection of 4 mg of triamcinolone acetonide(IVTA)for diffuse diabetic macular edema(DME).Methods:Eighty-six eyes of 74 patients with diffuse DME were randomized into 2 groups.The laser group eyes(n=48)were subjected to a macular grid laser photocoagulation 3 weeks after IVTA.The control group eyes(n=38)underwent only IVTA.Both groups were compared with regard to the changes in visual acuity and central macular thickness at 3 weeks,3 months,and 6 months after IVTA.Results:The mean central macular thickness before,3 weeks after,and 3 and 6 months after IVTA were 538,250,295,and 301μ m in the laser group vs 510,227,302,and 437 μ m in the control group,respectively.The logMAR visual acuities were not significantly different between the 2 groups at baseline and at 3 weeks after IVTA but were significantly better in the laser group at 3(P=.02)and 6 months(P<.001)after IVTA.Conclusions:Macular laser coagulation effectively maintains improved visual acuity after IVTA for diffuse DME and is believed to reduce recurrent DME after IVTA.

维替泊芬光动力疗法和玻璃体内注射曲安奈得治疗新生血管性老年性黄斑变性的疗效研究

Purpose:To examine the efficacy of photodynamic therapy(PDT)with verteporfin and intravitreal triamcinolone acetonide in the treatment of neovascular age-related macular degeneration(AMD).Design:Retrospective,interventional case series.Methods:Sixty eyes of 56 patients with neovascular AMD were treated with PDT with verteporfin followed by an intravitreal injection of 4 mg triamcinolone acetonide.The main outcome measures were visual acuity(VA),retreatment frequency with PDT(and triamcinolone),and frequency of side effects.Results:Mean follow-up was 15.9 months(range 12 to 30 months,median 15 months).Twenty-three(38.3%)of 60 eyes had a stable result at 12 months’follow-up(that is,loss/gain < three lines)and 34(56.7%)of 60 had a loss of 3 lines or more.Three patients(5%)had an improvement of 3 lines or more.Lesion type,patient age,and lesion size had no influence on the outcome,but baseline VA had a statistically significant effect(P=.006).The median number of PDT-intravitreal triamcinolone acetonide treatments was one.One-third(20 of 60)of all eyes had an increase in intraocular pressure(IOP)that required therapy.There were no cases of endophthalmitis,but 13 patients(21.6%)developed severe cataract that required surgery.Conclusions:The combination of PDT and intravitreal triamcinolone acetonide requires careful consideration as a treatment option for neovascular AMD.In our case series,this treatment combination did not prevent a considerable decrease in VA.The main benefit of this combination treatment was a low number of verteporfin treatments.Baseline VA was the main predictor of the final outcome.

曲安奈得用于增生性糖尿病性视网膜病变全视网膜光凝的辅助治疗

Objective:To evaluate intravitreal injection of triamcinolone acetonide before laser panretinal photocoagulation(PRP)in the treatment of proliferative diabetic retinopathy.Methods:This interventional case series included 9 patients with bilateral proliferative diabetic retinopathy.One eye received intravitreal triamcinolone before PRP(injected eye)and the other,PRP alone(control eye).The main outcome measures were the change in planimetric area of fluorescein leakage from retinal neovascularization and in central macular thickness on optical coherence tomography at 3,6,9,and 12months.Secondary end points were change in vision,intraocular pressure,and cataract progression.Results:All patients completed 9 months and 5 patients,12 months of follow-up.Initial mean(SD)planimetric area of fluorescein leakage and central macular thickness were 7.22(5.70)mm2 and 372.11(91.88)μ m in injected eyes and 9.08(6.17)mm2 and 355.33(115.23)μ m in control eyes,respectively.At the 9-and 12-month intervals,the planimetric area of fluorescein leakage decreased by 86% and 88% in injected eyes and 33% and 50% in controls,respectively.Central macular thickness significantly decreased in injected eyes and increased in control eyes.Vision slightly improved in injected eyes and worsened in control eyes.Conclusion:Intravitreal injection of triamcinolone before PRP may be useful in improving the effects of PRP in eyes with proliferative diabetic retinopathy by reducing neovascularization and macular thickening.