A hidden line removal algorithm for bi parametric surfaces is presented and illustrated by some experimental results. The enclosure test is done using area coordinates. A technique of moving box of encirclement is p...A hidden line removal algorithm for bi parametric surfaces is presented and illustrated by some experimental results. The enclosure test is done using area coordinates. A technique of moving box of encirclement is presented. It is found that the algorithm is of general purpose, requires minimal computer storage, has high accuracy and simplicity, and is very easy to be implemented on a computer.展开更多
Demand response has been intensively studied in recent years. It can motivate customers to change their consumption patterns according to the dynamic(time-varying) electricity price, which is considered to be the most...Demand response has been intensively studied in recent years. It can motivate customers to change their consumption patterns according to the dynamic(time-varying) electricity price, which is considered to be the most cost-effective and reliable solution for smoothing the demand curve. However, many existing schemes, based on users' demand request in each period, require users to consume their requested electricity exactly, which sometimes causes inconvenience and losses to the utility, because customers cannot always be able to consume the accurate electricity demand due to various personal reasons. In this paper, we tackle this problem in a novel approach. Instead of charging after consumption, we adopt the prepayment mechanism to implement power request. Furthermore, we propose a trading market running by the control center to cope with the users' dynamic demand. It is noteworthy that both users' original demand and trading records are protected against potential adversaries including the curious control center. Through the numerical simulation, we demonstrate that our scheme is highly efficient in both computation and communication.展开更多
Among several implicitization methods, the method based on resultant computation is a simple and direct one, but it often brings extraneous factors which are difficult to remove. This paper studies a class of rational...Among several implicitization methods, the method based on resultant computation is a simple and direct one, but it often brings extraneous factors which are difficult to remove. This paper studies a class of rational space curves and rational surfaces by implicitization with univaxiate resultant computations. This method is more efficient than the other algorithms in finding implicit equations for this class of rational curves and surfaces.展开更多
Active targeting drug delivery systems （TDDS）, which could improve drug therapeutic efficacy and reduce toxicity, are still the focus of many scientific researches in cancer therapy. The drug circulation time and tu...Active targeting drug delivery systems （TDDS）, which could improve drug therapeutic efficacy and reduce toxicity, are still the focus of many scientific researches in cancer therapy. The drug circulation time and tumor accumulation could be significantly increased with the application of sterically stabilized liposome （SSL）. SSL could also be modified easily with certain ligands to achieve targeting drug delivery. Because many tumors overexpress somatostatin receptors （SSTRs）, octreotide （OCT） becomes a potential targeting ligand due to its high affinity to SSTRs, especially to subtype 2 （SSTR2）. In this study, OCT was conjugated to methoxypolyethyleneglycol-distearoyl-phosphatidylethanolamine （DSPE-PEG2000）, and doxorubicin （DOX）-loaded SSL with a variable percentage of octreotide-methoxypolyethyleneglycol-distearoyl-phosphatidylethanolamine （DSPE-PEG/00o-OCT） were prepared （OCT-SSL-DOX）. All liposomes were about 90 nm in diameter and negatively charged on the surface, with DOX encapsulation efficiency at above 95%. OCT modification exhibited little effect on the physicochemical properties of SSL. In this study, cellular delivery efficacy of all prepared liposomes was evaluated in SSTIL2-positive cells in vitro by flow cytometry for the optimization of the OCT density on the surface of liposomes. Lipid formulation containing 1.5% DSPE-PEG20oo-OCT exhibited the highest efficiency of intracellular drug delivery. The modification of OCT did not alter the release behaviors of liposomal DOX in vitro, but OCT-SSL-DOX increased the cytotoxicity and improved the anti-tumor effect of liposomal DOX in SST1L2- positive cells and tumor-bearing mice models. In summary, OCT-modified SSL succeeded in increasing intracellular delivery and enhancing therapeutic efficacy of encapsulated anticancer agent, suggesting that it might be a promising TDDS for the treatment of SSTR2-overexpressing cancers.展开更多
In this paper we present a new representation of curve, named parametric curve with an implicit domain(PCID), which is a curve that exists in parametric form defined on an implicit domain. PCID provides a bridge betwe...In this paper we present a new representation of curve, named parametric curve with an implicit domain(PCID), which is a curve that exists in parametric form defined on an implicit domain. PCID provides a bridge between parametric curve and implicit curve because the conversion of parametric form or implicit form to PCID is very convenient and efficient. We propose a framework model for mapping given points to the implicit curve in a homeomorphic manner. The resulting map is continuous and does not overlap. This framework can be used for many applications such as compatible triangulation, image deformation and fisheye views. We also present some examples and experimental results to demonstrate the effectiveness of the framework of our proposed model.展开更多
It is important to reconstruct a continuous surface representation of the point cloud scanned from a human body. In this paper a new implicit surface method is proposed to reconstruct the human body surface from the p...It is important to reconstruct a continuous surface representation of the point cloud scanned from a human body. In this paper a new implicit surface method is proposed to reconstruct the human body surface from the points based on the combination of radial basis functions （RBFs） and adaptive partition of unity （PoU）. The whole 3D domain of the scanned human body is firstly subdivided into a set of overlapping subdomalns based on the improved octrees. The smooth local surfaces are then computed in the subdomalns based on RBFs. And finally the global human body surface is reconstructed by blending the local surfaces with the adaptive PoU functions. This method is robust for the surface reconstruction of the scanned human body even with large or non-uniform point cloud which has a sharp density variation.展开更多
An algorithm is given for computing in a very efficient way the topology of two real algebraic plane curves defined implicitly.The authors preform a symbolic pre-processing that allows us later to execute all numerica...An algorithm is given for computing in a very efficient way the topology of two real algebraic plane curves defined implicitly.The authors preform a symbolic pre-processing that allows us later to execute all numerical computations in an accurate way.展开更多
文摘A hidden line removal algorithm for bi parametric surfaces is presented and illustrated by some experimental results. The enclosure test is done using area coordinates. A technique of moving box of encirclement is presented. It is found that the algorithm is of general purpose, requires minimal computer storage, has high accuracy and simplicity, and is very easy to be implemented on a computer.
基金supported by the National Key Research and Development Plan of China under Grant No.2016YFB0800301the Fund of Science and Technology on Communication Networks Laboratory under Grant No.KX162600024Youth Innovation Promotion Association CAS under Grant No.2016394
文摘Demand response has been intensively studied in recent years. It can motivate customers to change their consumption patterns according to the dynamic(time-varying) electricity price, which is considered to be the most cost-effective and reliable solution for smoothing the demand curve. However, many existing schemes, based on users' demand request in each period, require users to consume their requested electricity exactly, which sometimes causes inconvenience and losses to the utility, because customers cannot always be able to consume the accurate electricity demand due to various personal reasons. In this paper, we tackle this problem in a novel approach. Instead of charging after consumption, we adopt the prepayment mechanism to implement power request. Furthermore, we propose a trading market running by the control center to cope with the users' dynamic demand. It is noteworthy that both users' original demand and trading records are protected against potential adversaries including the curious control center. Through the numerical simulation, we demonstrate that our scheme is highly efficient in both computation and communication.
基金supported by the Natural Science Foundation of China under Grant No. 10901163the Knowledge Innovation Program of the Chinese Academy of Sciences
文摘Among several implicitization methods, the method based on resultant computation is a simple and direct one, but it often brings extraneous factors which are difficult to remove. This paper studies a class of rational space curves and rational surfaces by implicitization with univaxiate resultant computations. This method is more efficient than the other algorithms in finding implicit equations for this class of rational curves and surfaces.
基金National Basic Research Program of China(Grant No.2009CB930300)State Key Projects(Grant No.2009ZX09310-001)the 863 Project of China(Grant No.2007AA021811)
文摘Active targeting drug delivery systems （TDDS）, which could improve drug therapeutic efficacy and reduce toxicity, are still the focus of many scientific researches in cancer therapy. The drug circulation time and tumor accumulation could be significantly increased with the application of sterically stabilized liposome （SSL）. SSL could also be modified easily with certain ligands to achieve targeting drug delivery. Because many tumors overexpress somatostatin receptors （SSTRs）, octreotide （OCT） becomes a potential targeting ligand due to its high affinity to SSTRs, especially to subtype 2 （SSTR2）. In this study, OCT was conjugated to methoxypolyethyleneglycol-distearoyl-phosphatidylethanolamine （DSPE-PEG2000）, and doxorubicin （DOX）-loaded SSL with a variable percentage of octreotide-methoxypolyethyleneglycol-distearoyl-phosphatidylethanolamine （DSPE-PEG/00o-OCT） were prepared （OCT-SSL-DOX）. All liposomes were about 90 nm in diameter and negatively charged on the surface, with DOX encapsulation efficiency at above 95%. OCT modification exhibited little effect on the physicochemical properties of SSL. In this study, cellular delivery efficacy of all prepared liposomes was evaluated in SSTIL2-positive cells in vitro by flow cytometry for the optimization of the OCT density on the surface of liposomes. Lipid formulation containing 1.5% DSPE-PEG20oo-OCT exhibited the highest efficiency of intracellular drug delivery. The modification of OCT did not alter the release behaviors of liposomal DOX in vitro, but OCT-SSL-DOX increased the cytotoxicity and improved the anti-tumor effect of liposomal DOX in SST1L2- positive cells and tumor-bearing mice models. In summary, OCT-modified SSL succeeded in increasing intracellular delivery and enhancing therapeutic efficacy of encapsulated anticancer agent, suggesting that it might be a promising TDDS for the treatment of SSTR2-overexpressing cancers.
基金supported by National Natural Science Foundation of China(Grant Nos.11031007,11171322,61222206 and 11371341)One Hundred Talent Project of the Chinese Academy of Sciencesthe Program for New Century Excellent Talents in University(Grant No.NCET-11-0881)
文摘In this paper we present a new representation of curve, named parametric curve with an implicit domain(PCID), which is a curve that exists in parametric form defined on an implicit domain. PCID provides a bridge between parametric curve and implicit curve because the conversion of parametric form or implicit form to PCID is very convenient and efficient. We propose a framework model for mapping given points to the implicit curve in a homeomorphic manner. The resulting map is continuous and does not overlap. This framework can be used for many applications such as compatible triangulation, image deformation and fisheye views. We also present some examples and experimental results to demonstrate the effectiveness of the framework of our proposed model.
基金the National Natural Science Foundation of China (No. 50575139)the Shanghai Special Fund of Informatization (No. 088)
文摘It is important to reconstruct a continuous surface representation of the point cloud scanned from a human body. In this paper a new implicit surface method is proposed to reconstruct the human body surface from the points based on the combination of radial basis functions （RBFs） and adaptive partition of unity （PoU）. The whole 3D domain of the scanned human body is firstly subdivided into a set of overlapping subdomalns based on the improved octrees. The smooth local surfaces are then computed in the subdomalns based on RBFs. And finally the global human body surface is reconstructed by blending the local surfaces with the adaptive PoU functions. This method is robust for the surface reconstruction of the scanned human body even with large or non-uniform point cloud which has a sharp density variation.
文摘An algorithm is given for computing in a very efficient way the topology of two real algebraic plane curves defined implicitly.The authors preform a symbolic pre-processing that allows us later to execute all numerical computations in an accurate way.
