A HPLC method for determination of gatifloxacin and sodium chloride injection was presented. A Shim-Pack CLC-ODS column was used with mobile phase of 0.02 mol/L potassium dihydrogen phosphate buffer solution ( pH4.0 ...A HPLC method for determination of gatifloxacin and sodium chloride injection was presented. A Shim-Pack CLC-ODS column was used with mobile phase of 0.02 mol/L potassium dihydrogen phosphate buffer solution ( pH4.0 , adjusted with H3PO4)-acetonitrile (85∶15, containing 2 mmol/L tetrabutylammonium bromide) at detection wavelength of 292 nm . It had a good linearity over the concentration range of 4~ 32 μg/ml . The average recovery was 98.5% with RSD of 0.7% .展开更多
文摘A HPLC method for determination of gatifloxacin and sodium chloride injection was presented. A Shim-Pack CLC-ODS column was used with mobile phase of 0.02 mol/L potassium dihydrogen phosphate buffer solution ( pH4.0 , adjusted with H3PO4)-acetonitrile (85∶15, containing 2 mmol/L tetrabutylammonium bromide) at detection wavelength of 292 nm . It had a good linearity over the concentration range of 4~ 32 μg/ml . The average recovery was 98.5% with RSD of 0.7% .